Targeted Next-Generation Sequencing in Pneumonia: Applications in the Detection of Responsible Pathogens, Antimicrobial Resistance, and Virulence by Liu B, Bao Z, Chen W, Xi X, Ge X, Zhou J, Zheng X, Zhang P, Deng W, Ding R, Zhou M, Fang J

“…., Nanjing, 210018, People’s Republic of China; 6Department of Pulmonary and Critical Care Medicine, Zhoushan Branch of Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Zhoushan, 316000, People’s Republic of China; 7Department of Pharmacy, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jie Fang, Department of Pharmacy, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197, Rui Jin 2nd Road, Shanghai, 200025, People’s Republic of China, Email fj40517@rjh.com.cn Min Zhou, Department of Pulmonary and Critical Care Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197, Rui Jin 2nd Road, Shanghai, 200025, People’s Republic of China, Email doctor_zhou_99@163.comBackground: Targeted next-generation sequencing (tNGS) is a high-throughput and cost-effective diagnostic alternative for pneumonia, with the ability to simultaneously detect pathogens, antimicrobial resistance genes, and virulence genes. …”
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Lattes/Lattara (Hérault), comptoir étrusque du littoral languedocien by Éric Gailledrat, Ariane Vacheret

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Laser powder bed fusion processed LaCe(Fe, Mn, Si)₁₃ lattices for magnetic refrigeration: Process optimization, microstructure, and magnetocaloric performance by Kun Sun, Yuting Zhang, Sheng Li, Zhaohe Gao, Xue Cao, Ziling Peng, Pengyan Huang, Abd El-Moez A. Mohamed, Zhigang Zheng, Minki Jeong, Yu-Lung Chiu, Yang Lu, Moataz M. Attallah

“…The ΔSm of HTHed Diamond around Tc (1.13 J kg−1K−1 at 219.5 K) is slightly higher than HTHed Gyroid (0.99 J kg−1K−1 at 250.5 K). Essentially, our work accelerates the search for optimal process parameters and guides the direction for lattice design of LaCe(Fe,Mn,Si)13.…”
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Establishing a radiomics model using contrast-enhanced ultrasound for preoperative prediction of neoplastic gallbladder polyps exceeding 10 mm by Dong Jiang, Yi Qian, Yijun Gu, Ru Wang, Hua Yu, Zhenmeng Wang, Hui Dong, Dongyu Chen, Yan Chen, Haozheng Jiang, Yiran Li

“…This model, derived from machine learning frameworks including Support Vector Machine (SVM), Logistic Regression (LR), Multilayer Perceptron (MLP), k-Nearest Neighbors (KNN), and eXtreme Gradient Boosting (XGBoost) with fivefold cross-validation, showed AUCs of 0.95 (95% CI: 0.90–0.99) and 0.87 (95% CI: 0.72–1.0) in internal validation. …”
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Intracranial complications in adult patients with severe pneumococcal meningitis: a retrospective multicenter cohort study by Camille Legouy, Renaud Cornic, Keyvan Razazi, Damien Contou, Stéphane Legriel, Eve Garrigues, Pauline Buiche, Maxens Decavèle, Sarah Benghanem, Thomas Rambaud, Jérôme Aboab, Marina Esposito-Farèse, Jean-François Timsit, Camille Couffignal, Romain Sonneville

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İlk En Kapsamlı Türkçe Fıkıh Eseri: Hukukı İslâmiyye ve Istılahatı Fıkhiyye Kamusu by Talip Türcan

“…Methal’in ilk bölümü (Birinci Kitap), fıkıh usûlü terimlerine, usûlün temel konularına, Mecelle’deki 99 küllî kâide ile diğer bir kısım küllî fıkıh kâidelerinin şerhine ayrılmıştır. …”
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Prehospital scale to differentiate intracerebral hemorrhage from large-vessel occlusion patients: a prospective cohort study by A. Freixa-Cruz, G. Jimenez-Jimenez, G. Mauri-Capdevila, Y. Gallego-Sánchez, A. García-Díaz, R. Mitjana-Penella, M. Paul-Arias, C. Pereira-Priego, E. Ruiz-Fernández, S. Salvany-Montserrat, A. Sancho-Saldaña, E. San-Pedro-Murillo, E. Saureu, D. Vázquez-Justes, Francisco Purroy

“…A score ≥ 4 exhibited a sensitivity of 0.10, a specificity of 0.99, a positive predictive value of 0.21, and a negative predictive value of 0.98. …”
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Association of Cardiovascular Risk Factors With Major and Minor Electrocardiographic Abnormalities: A Report From the Cross‐Sectional Phase of Tehran Cohort Study by Pooria Ahmadi, Sajjad Ahmadi‐Renani, Parmida Sadat Pezeshki, Sepehr Nayebirad, Arash Jalali, Akbar Shafiee, Aryan Ayati, Arian Afzalian, Farshid Alaeddini, Soheil Saadat, Farzad Masoudkabir, Ali Vasheghani‐Farahani, Saeed Sadeghian, Mohamamdali Boroumand, Abbasali Karimi, Boshra Pourbashash, Kaveh Hosseini, Frits R. Rosendaal

“…Results A total of 756 (9.9%) participants had major ECG abnormalities, while minor abnormalities were detected in 2526 (33.1%). …”
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Phytochemical Analysis, Antioxidant Activity, Antimicrobial Activity, and Cytotoxicity of Chaptalia nutans Leaves by Letiele Bruck de Souza, Amanda Leitão Gindri, Thainara de Andrade Fortes, Thais Felli Kubiça, Jefferson Enderle, Rafael Roehrs, Sidnei Moura e Silva, Vanusa Manfredini, Elton Luís Gasparotto Denardin

“…A quantitative phytochemical study indicated the total phenol (30.17 ± 1.44 mg/g), flavonoid (21.64 ± 0.66 mg/g), and condensed tannins (9.58 ± 0.99 mg/g). DPPH (345.41 ± 5.35 μg/mL) and FRAP (379.98 ± 39.25 μM FeSO4/mg sample) show to extract of C. nutans leaves an intermediate value, indicating moderate antioxidant activity of the extract. …”
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Analysis and comparison of the trends in burden of spinal cord injury in China and worldwide from 1990 to 2021: an analysis of the global burden of disease study 2021 by Hao Qin, Yuhang Diao, Mingyu Hao, Zhitan Wang, Minghao Xie, Xiaojun Hu, Tao Zhu

“…The autoregressive integrated moving average (ARIMA) model was then applied to project SCI trends for the next 15 years.ResultsIn 2021, the prevalence and incidence of SCI in China reached 2,766,277 and 99,363 cases, respectively, marking increases of 63.27 and 43.27% since 1990. …”
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Comprehensive evaluation of physico-chemical, antioxidant, and antimicrobial properties in commercial soaps: A study on bar soaps and liquid hand wash by Jannatul Ferdous Nova, Susmita Zaman Smrity, Mahadi Hasan, Md. Tariquzzaman, Md Al Amin Hossain, Md. Tanvirul Islam, Md. Raysul Islam, Selina Akter, Md. Sifat Rahi, Md. Tuhinur R. Joy, Zannatul Kowser

“…Combining all the parameters, SN 3 has good results among bar soaps with mild moisturizing and cleansing properties (MC-8.30 ± 0.035 %, FH-22.33 ± 0.29 cm), is safe for the skin (pH-9.83 ± 0.02, TAC-0.99 ± 0.03), has good TFM values (72.89 %), has proficient bacteria growth-inhibiting properties (ZI-18.67 ± 0.29 mm/100 % conc.) and has the ability to remove free radicals (357.41 ± 2.07 μg/mL). …”
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Health-related quality of life and health state utility value in idiopathic pulmonary fibrosis: a systematic review and meta-analysis by Guixiang Zhao, Siyuan Lei, Ya Li, Zhenzhen Feng, Jiansheng Li

“…The results of the meta-analysis revealed that the pooled SGRQ total score was 45.28 (95% confidence interval [CI] 41.10-49.47), the mean EQ-5D utility score was 0.75 (95% CI: 0.72–0.79), the total EQ-5D VAS score was 66.88 (95% CI: 63.75–70.01), and the pooled SF-36 physical component summary (PCS) and mental component summary (MCS) score were 36.70 (95% CI: 32.98–40.41) and 48.99 (95% CI: 47.44–50.55), respectively. The total KBILD score was 58.31 (95% CI: 55.43–61.19), the IPF specific version of the SGRQ (SGRQ-I) was 40.38 (95% CI: 28.81–51.96) and the Leicester Cough Questionnaire (LCQ) score was 16.09 (95% CI: 15.45–16.74). …”
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Risk factors for gastric cancer and related serological levels in Fujian, China: hospital-based case–control study by Lin Cai, Wen Wang, Ping Yuan, Lan Lin, Kuicheng Zheng, Sihan Wu, Liangxiang Huang, Bingshan Wu, Tiehui Chen, Xiaoqing Li

“…Eating hot food (OR=2.32), eating pickled vegetables (OR=4.05) and often feel troubled (OR=2.21) were found to significantly increase the risk of gastric cancer (all p<0.05), while consuming onion or garlic (OR=0.35), drinking tea (OR=0.26), eating fresh fruits (OR=0.55), and high serum PG I (OR=0.99) or PG I/II ratio (OR=0.73) were found to be protective against gastric cancer.Conclusion Study results showed that serum PG, G-17 and H. pylori antibodies could be useful indicators for early diagnosis of gastric cancer. …”
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Acute phase responses in clinically healthy multiparous Holsteins with and without calcium dysregulation during the early postpartum period by J.A. Seminara, C.R. Seely, J.A.A. McArt

“…Dyscalcemic cows had elevated concentrations of SAA beginning at 2 DIM (eucalcemic: mean = 13.88 µg/mL, 95% CI = 11.34 to 16.99 µg/mL; dyscalcemic: mean = 32.95 µg/mL, 95% CI = 24.55 to 44.21 µg/mL) and continuing through 4 DIM (eucalcemic: mean = 8.14 µg/mL, 95% CI = 6.66 to 9.95 µg/mL; dyscalcemic: mean = 30.01 µg/mL, 95% CI = 22.60 to 39.83 µg/mL). …”
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Gegen Qinlian Decoction Attenuates Colitis-Associated Colorectal Cancer via Suppressing TLR4 Signaling Pathway Based on Network Pharmacology and In Vivo/In Vitro Experimental Valid... by Yaoyao Xu, Qiaoyan Cai, Chunyu Zhao, Weixiang Zhang, Xinting Xu, Haowei Lin, Yuxing Lin, Daxin Chen, Shan Lin, Peizhi Jia, Meiling Wang, Ling Zhang, Wei Lin

“…Through data platform analysis, it was concluded that there were 1104 target genes of GQD and 2022 target genes of CAC. Moreover, there were 99 intersecting genes between GQD and CAC. The core targets of GQD contained NFKB1, IL1B, IL6, TLR4, and TNF, and GQD reduced inflammation by inhibiting the TLR4 signaling pathway. …”
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Safe distances for transforaminal posterior lumbar interbody fusion under one-hole split endoscopy: three-dimensional reconstruction measurement of 1-degree degenerative lumbar spo... by Changzhen Liu, Jiabin Ren, Zhaozhong Sun, Sa Li, Zhimeng Feng, Yuefei Li

“…Results In the DLS group and non-DLS group, the VD1 were (10.97 ± 2.15) mm and (11.32 ± 1.70) mm, the VD2 were (11.06 ± 1.75) mm and (10.96 ± 0.91) mm, the VD3 were (4.76 ± 1.54) mm and (5.01 ± 1.02) mm, the HD1 were (10.54 ± 1.49) mm and (10.97 ± 1.06) mm, the HD2 were (17.43 ± 2.01) mm and (17.32 ± 1.70) mm, and the HD3 were (2.21 ± 0.99) mm and (2.11 ± 1.33) mm. These measurement distances were not significantly different between the two groups. …”
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تاثیر بذر و پیش‌تیمار آن بر عملکرد و صفات دو رقم پیاز خوراکی (Allium cepa L.) by موسی ایزدخوان شیشوان, مهدی تاج بخش شیشوان, بهمن پاسبان اسلام, جلال جلیلیان

“…پرایمینگ بذر موجب بهبود عملکرد بیولوژیکی و صفات رویشی و فنولوژی گردید به طوری که بیشترین عملکرد بیولوژیکی، سطح برگ، شاخص سطح برگ و شاخص سوخ‌دهی به ترتیب 98/105تن در هکتار 77/123 سانتی‌مترمربع،25/8 و 99/4 به پرایمینگ با فولامین تعلق داشت و کمترین آنها از تیمار شاهد به‌دست آمد. …”
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Computational Fluid Dynamics Analysis of Nasal Airway Changes after Treatment with C-Expander by Wang Xiao, Siling Liu, Yanqin Lu, Lei Lei, Ning Liu, Xiaoping Shen, Yuhong He, Ousheng Liu

“…The nasal pressure drop decreased from 36.34±3.99 Pa to 30.70±3.17 Pa (P<0.05), while the value of the maximum velocity decreased from 6.50±0.31 m/s to 5.85±0.37 m/s (P<0.05). …”
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Performance of a hybrid capture-based target enrichment next-generation sequencing for the identification of respiratory pathogens and resistance-associated genes in patients with... by Wei-Yu Hsu, Ting-Wei Kao, Hsin-Ching Cho, Sheng-Yuan Ruan, Tai-Fen Lee, Yu-Tsung Huang, Jung-Yien Chien

“…Overall, the positive and negative agreement rates for bacterial detection were 63.6% and 97.5% between RPIP and culture methods, respectively, and 55.8% and 99.4% between FilmArray-PN and culture methods, respectively. …”
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L’africanisation de l’Église évangélique au Maroc : revitalisation d’une institution religieuse et dynamiques d’individualisation by Bernard Coyault

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