Liquid chromatography-tandem mass spectrometry for the quantification of ripretinib and its metabolites DP-5439 in human plasma by Jiahui Lin, Jiahui Lin, Aiting Jiang, Juntao Zheng, Jingjing Wu, Hao Li, Hao Li, Shirong Cai, Yulong He, Xiao Chen, Guoping Zhong, Ke-Jing Tang, Ke-Jing Tang, Xinhua Zhang, Yanzhe Xia

“…Plasma samples from ripretinib-treated patients of our hospital were collected for pharmacokinetic analysis.ResultsRipretinib and DP-5439 demonstrated a strong linear relationship over 10–5,000 μg/L (R2 > 0.99). Accuracy, precision, specificity, recoveries, matrix effect, stability, and dilution effect were all validated and found to meet the required criteria. …”
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Effect of acupoint application of Traditional Chinese Medicine on recovery of gastrointestinal function after cesarean section (中药穴位敷贴促进剖宫产术后胃肠功能恢复的效果观察)... by PENG Rufeng (彭茹凤), LI Fengmin (黎凤民), HUANG Ling (黄翎), HUANG Huan (黄环), SU Qiumei (苏秋梅)

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Gut microbiota influence on lung cancer risk through blood metabolite mediation: from a comprehensive Mendelian randomization analysis and genetic analysis by Yizhao Du, Qin Wang, Zongmei Zheng, Hailun Zhou, Yang Han, Ao Qi, Lijing Jiao, Lijing Jiao, Yabin Gong

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Особливості протимікробної дії препаратів полігексаніду до домінуючих збудників ранової інфекції в Україні: сучасні реалії... by O.A. Nazarchuk, P.S. Rusak, R.M. Chornopyshchuk, T.V. Denysko, I.M. Vovk, D.I. Grebeniuk, A.S. Skrypka, N.P. Chornopyshchuk

“…МЦК полігексаніду для клінічних штамів золотистого стафілококу мали найнижчі значення і достовірно відрізнялися від таких щодо E. coli у 2,21 раза, K. pneumoniae - в 1,99 раза, A. baumannii - у 3,4 раза, P. aeruginosa - у 4,52 раза. …”
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Decomposing the Poor-Non-Poor Gap in the Prevalence of Undiagnosed and Untreated Hypertension Among Bangladeshi Population by Mosiur Rahman, Mahfuza Khatun, Asrafun Naher Pinkey, Syed Emdadul Haque, Farhana Akhter Liza, Md. Nuruzzaman Haque, Prosannajid Sarkar, Tapan Kumar Roy, G. M. Rabiul Islam, Md. Rashed Alam, Mahmudul Hasan, Izzeldin Fadl Adam, Nguyen Huu Chau Duc, Saber Al-Sobaihi, Abid Hasan

“…People in the poor SES groups had a 0.88 times (95% confidence interval [CI] 0.77–0.99) lower likelihood of having hypertension compared to those in the non-poor SES group. …”
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Economic and environmental sustainability of agriculture production at the crop level by A.Z. Bi, K.B. Umesh, B. Md Abdul, D. Sivakumar, P. Srikanth

“…The sustainability scores of farmers were found to be 50.99 and 67.65 under the composite sustainability score under rainfed conditions. …”
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Gestational diabetes mellitus and offspring’s carotid intima–media thickness at birth: MySweetHeart Cohort study by Umberto Simeoni, Antje Horsch, Arnaud Chiolero, Yvan Vial, Nicole Sekarski, Jardena J Puder, Pascal Bovet, Stefano Di Bernardo, Yvan Mivelaz, Adina Mihaela Epure, Sandrine Estoppey Younes, Bobby Stuijfzand, Leah Gilbert, Stefano Lanzi, Justine Gross, Stefano Di Bernardo, Dan Quansah, Jean-Benoît Rossel, Amar Arhab, Sandrine Estoppey Younes, Seyda Mayerat

“…Offspring’s CIMT was measured by ultrasonography after birth (range 1–19 days).Results Data on CIMT were available for 99 offspring of women without GDM and 101 offspring of women with GDM. …”
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Prevalence of anaemia and the associated factors among hospitalised people living with HIV receiving antiretroviral therapy in Southwest China: a cross-sectional study by Jie Yuan, Hai Long, Min Liu, Juan He, Jue Liu, Yu Wu, Wenzhan Jing, Min Du, Manna Zhang, Yaping Wang, Su Song, Siqi Liu, Guiying Cao, Yuedong Liang, Xiaoxin Xie, Yanhua Fu

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PseudoCell: Hard Negative Mining as Pseudo Labeling for Deep Learning-Based Centroblast Cell Detection by Narongrid Seesawad, Piyalitt Ittichaiwong, Thapanun Sudhawiyangkul, Phattarapong Sawangjai, Peti Thuwajit, Paisarn Boonsakan, Supasan Sripodok, Kanyakorn Veerakanjana, Komgrid Charngkaew, Ananya Pongpaibul, Napat Angkathunyakul, Narit Hnoohom, Sumeth Yuenyong, Chanitra Thuwajit, Theerawit Wilaiprasitporn

“…Depending on the confidence threshold, <italic>PseudoCell</italic> can eliminate 58.18-99.35&#x0025; of irrelevant tissue areas on WSI, streamlining the diagnostic process. …”
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Investigation of vitamin D deficiency in girls with growth and development variations—a single center study by Panwang Huang, Panwang Huang, Beilei Zeng, Beilei Zeng, Feng Ren, Yuan Zhou, Yuan Zhou, Ye Li, Ye Li, Yinyin Huang, Yinyin Huang, Xingyu Liu, Xingyu Liu, Jiaxiu Zhou, Jiaxiu Zhou, Yaping Ma, Yaping Ma

“…The 25(OH)D &lt;20 ng/ml was used as the standard for vitamin D deficiency.ResultsThe levels of vitamin D in the early puberty group, menarche group, obesity group, short stature group, and control group were as follows: 20.23 ± 5.90 ng/ml, 17.85 ± 5.69 ng/ml, 21.31 ± 8.99 ng/ml, 27.90 ± 12.27 ng/ml, and 29.42 ± 12.65 ng/ml, respectively. …”
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Prevalence and determinants of HIV testing-seeking behaviors among women of reproductive age in Tanzania: analysis of the 2022 Demographic and health survey by Jackson Micheal Asingwire, Isaac isiko, Kuli Faith Rombe, Aaron Mwesigwa, Emmanuel Asher Ikwara, Haron Olot, Lenz Nwachinemere Okoro, Manankong Jane Precious Izunwanne, Blessing Onyinyechi Agunwa, Abdul Aziiz Bwana, William Yiga Kalemba, Ebuka Louis Anyamene

“…Women who have heard about PrEP but are not uncertain about its approval [AOR: 36.07, CI (3.33–390.25)], respondents who have tested before with HIV testing kits [AOR:35.99, CI (4.00–324.13)] and women who are aware of HIV testing kids but never tested with them before [AOR: 2.80, CI (1.19–6.58)] are predictors of HIV testing seeking behaviors. …”
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Abortion-related complications in Brazil: results from the World Health Organization Multi-country Survey on Abortion (MCS-A) by Nelio Neves Veiga Junior, Luiz Francisco Cintra Baccaro, Adriana Mendonça da Silva Alexandrino, Alexandre Volta Andrade do Nascimento, Camila Tereza Camilo Clerot, Cintya Andreia do Nascimento Santos, Claudia Lucrécia de Matos Silva, Claudio Lucio de Medeiros Albuquerque, Débora Paulo Santos, Demétrio Antonio Gonçalves da S. Gomes, Édson Cunha de Araújo Junior, Elizabete das Chagas Vilanova, Georgina Costa Teixeira, Graciete Helena Nascimento dos Santos, Guilherme Augusto Guerra Avelar, Iara Elce Lopes Barros, Jaqueline Polon Abboud, Jeane Cristina Antas Lins, Joanne Thalita Pereira Silva, Kelma H. Aguiar de Lucena, Lara Wanderley Paes Barbosa, Lia Ferreira Caixeta Barreto de Siqueira, Luciana de Melo Freitas Carneiro, Lucila Nagata, Márcia de Oliveira Pereira Lúcio, Maria Cleane Rodrigues da Silva, Maria da Conceição Ribeiro Simões, Maria Fernanda da Mota Magalhães, Mariana Viana Almeida, Michelle Regina Faria Lira, Nádia Martins de Paula Souza, Rafael Martins Papa, Rafael Ribeiro Matos, Renata Porto Pinheiro, Roberta Souza dos Anjos, Suelen Miranda de Jesus, Tedy Roger Flores Ynturias, Valéria Cristina Gonçalves, Viviane Resende de Abreu Caetano

“…Factors associated with PLTC/SMO vs mild complications were having a gestational age ≥ 13 weeks (pravlence ratio - PR = 3.09; 95% confidence interval - 95%CI: 1.42-6.72), having been treated in Maranhão (PR = 0.27; 95%CI: 0.12-0.63) and in Rondônia (PR = 0.64; 95%CI: 0.20-0.99). Factors associated with moderate vs. mild complications were expulsion of products of conception before arrival to health facility (PR = 2.55; 95%CI: 1.64-3.96) and having been treated in Maranhão (PR = 0.58; 95%CI: 0.38-0.87). …”
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Analisis Klasifikasi Sentimen Ulasan pada E-Commerce Shopee Berbasis Word Cloud dengan Metode Naive Bayes dan K-Nearest Neighbor by Josua Josen Alexander Limbong, Irwan Sembiring, kristoko dwi hartomo

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Community benefits of mass distribution of three types of dual-active-ingredient long-lasting insecticidal nets against malaria prevalence in Tanzania: evidence from a 3-year clust... by Eliud Andrea Lukole, Jackie Cook, Jacklin F Mosha, Nancy S Matowo, Manisha A Kulkarni, Elizabeth Mallya, Tatu Aziz, Jacklin Martin, Mark Rowland, Immo Kleinschmidt, Alphaxard Manjurano, Franklin W Mosha, Natacha Protopopoff

“…Among non-users, community-level usage of > 40% of dual-AI LLIN was significantly associated with protection against malaria infection: chlorfenapyr arm (OR: 0.44 (95% CI: 0.27–0.71), p = 0.0009), PBO arm (OR: 0.55 (95% CI: 0.33–0.94), p = 0.0277) and pyriproxyfen arm (OR: 0.61 (95% CI: 0.37–0.99), p = 0.0470) compared with non-users in clusters with > 40% usage of pyrethroid-only LLINs. …”
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Comparative analysis of ambient, in-home, and personal exposures reveals associations between breathing zone pollutant levels and asthma exacerbations in high-risk children by Camille M. Moore, Jonathan Thornburg, Elizabeth A. Secor, Katharine L. Hamlington, Allison M. Schiltz, Kristy L. Freeman, Jamie L. Everman, Tasha E. Fingerlin, Andrew H. Liu, Max A. Seibold

“…Personal NO2, O3, and PM10 exposures ranged from < 2 to 99.1 parts per billion (ppb), < 1.5 to 23.3 ppb, and < 1 to 141.9 𝜇g/m3, respectively. …”
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Meta Analysis of the Randomized Controlled Trial of Acupuncture for Ankylosing Spondylitis by Ping LI, Yinjie WANG, Jigang TIAN

“…However, there were no significant differences in improving the disease activity index of ankylosing spondylitis score [<italic>MD</italic>=-5.36, 95%<italic>CI</italic>(-12.99, -2.26), <italic>P</italic>=0.17], the functional index of ankylosing spondylitis score [<italic>MD</italic>=-4.25, 95%<italic>CI</italic>(-8.81, 0.31), <italic>P</italic>=0.07] and the adverse reaction rate [<italic>OR</italic>=0.12, 95%<italic>CI</italic>(0.01, 1.64), <italic>P</italic>=0.11] between the two groups(<italic>P</italic>&gt; 0.05). …”
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Maternal Macronutrient Intake and Associated Risk for Gestational Diabetes Mellitus: Results from the BORN2020 Study by Antigoni Tranidou, Ioannis Tsakiridis, Emmanuela Magriplis, Aikaterini Apostolopoulou, Violeta Chroni, Eirini Tsekitsidi, Ioustini Kalaitzopoulou, Nikolaos Pazaras, Michail Chourdakis, Themistoklis Dagklis

“…Pre-pregnancy energy intake exceeding EFSA recommendations was associated with increased GDM risk (aOR = 1.99, 95%CI: 1.37–2.86). During mid-gestation, higher dietary fiber intake (aOR = 1.05, 95%CI: 1.00–1.10), higher protein intake (aOR = 1.02, 95% CI: 1.00–1.04), and higher protein percentage of energy intake (aOR = 1.08, 95%CI: 1.01–1.17) were all significantly associated with increased GDM risk. …”
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Universal capillary screening for chronic autoimmune, metabolic and cardiovascular diseases: feasibility and acceptability of the UNISCREEN study by Sara Angiulli, Aurora Merolla, Elisa Borgonovo, Rebecca De Lorenzo, Serena Spadoni, Barbara Fontana, Giuseppina Manganaro, Elena Rela, Alberto Bongiovanni, Rita Peracino, Chiara Bellino, Giulia Pata, Eleonora Bianconi, Sabina Martinenghi, Francesca Ulivi, Cristina Renzi, Cristina Renzi, Emanuele Bosi, Emanuele Bosi, UNISCREEN Study Group, Sara Angiulli, Aurora Merolla, Alberto Bongiovanni, Rebecca De Lorenzo, Elena Rela, Rita Peracino, Chiara Bellino, Giuseppina Manganaro, Elisa Borgonovo, Sara Critelli, Aldo Fici, Martina Mallus, Giulia Morocutti, Giulia Pata, Clara Soggetti, Chiara Calabrese, Alberico Di Resta, Maria Pia Ruggiero, Antonella Spano’, Francesca Biasco, Manuel Stocchi, Pietro Melodia, Giuseppe Ancona, Andrea Laurenzi

“…Sufficient serum for late autoantibody testing was obtained in 99.7% of participants. The questionnaires showed overall satisfaction, with over 90% of participants considering capillary sampling simple and practical, and preferring it to venous sampling. …”
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Studying the Digital Intervention Engagement–Mediated Relationship Between Intrapersonal Measures and Pre-Exposure Prophylaxis Adherence in Sexual and Gender Minority Youth: Second... by Michael P Williams, Justin Manjourides, Louisa H Smith, Crissi B Rainer, Lisa B Hightow-Weidman, Danielle F Haley

“…ResultsFor every US $1 earned above the mean (US $96, SD US $35.1), participants had 2% (OR 0.98, 95% CI 0.97-0.99) lower odds of PrEP nonadherence. Frequently using phone apps to track health information was associated with a 71% (OR 0.29, 95% CI 0.06-0.96) lower odds of PrEP nonadherence. …”
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Associations of prenatal urinary melamine, melamine analogues, and aromatic amines with gestational duration and fetal growth in the ECHO Cohort by Giehae Choi, Xiaoshuang Xun, Deborah H. Bennett, John D. Meeker, Rachel Morello-Frosch, Sheela Sathyanarayana, Susan L Schantz, Leonardo Trasande, Deborah Watkins, Edo D. Pellizzari, Wenlong Li, Kurunthachalam Kannan, Tracey J. Woodruff, Jessie P. Buckley

“…Similarly in secondary analyses using categorical outcomes, an IQR increase in log2(melamine) was associated with 1.22 [0.99, 1.50] higher odds of post-term (>40 &amp; ≤42 weeks) as compared to full-term (≥38 &amp; ≤40 weeks). …”
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