Biological Safety Studies and Simultaneous Determination of Linagliptin and Synthetic Impurities by LC-PDA by Raquel Balestri Heleno Ferreira, Jonathaline Apollo Duarte, Flávio Dias Ferreira, Luis Flávio Souza de Oliveira, Michel Mansur Machado, Marcelo Donadel Malesuik, Fávero Reisdorfer Paula, Martin Steppe, Elfrides Eva Shermann Schapoval, Clésio Soldateli Paim

“…The % recovery of the LGT and added impurity were in the range of 92.92–99.79%. The precision of the method showed values less than 1.47% for LGT and less than 4.63% for impurities. …”
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Vocabulario, narración y argumentación en los primeros años de la infancia y la niñez. Una revisión de investigaciones / Vocabulary, narration and argumentation during the first ye... by Celia Renata Rosemberg, Alejandra Menti, Alejandra Stein, Florencia Alam, Maia Migdalek

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Study of cardiovascular risk in type 2 diabetic patients in the acute phase of the coronavirus infection and post-COVID period on the background of therapy with sodium-glucose cotr... by N.M. Kushnarоva, O.V. Zinych, A.A. Shuprovych, K.P. Komisarenko

“…In 9 months of treatment, a significant decrease was noted in serum level of homocysteine, which was elevated in the acute period of COVID-19 and reached normal values: in group 1, from 16.8 to 9.9; in group 2, from 14.4 to 10.1 μmol/l; p < 0.05. …”
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Predictors of Cardiovascular Autonomic Neuropathy Onset and Progression in a Cohort of Type 1 Diabetic Patients by M. Matta, A. Pavy-Le Traon, S. Perez-Lloret, C. Laporte, I. Berdugo, N. Nasr, H. Hanaire, J. M. Senard

“…Methods. 175 type 1 diabetic patients (mean age: 50 ± 11 years; female/male: 76/99) with positive bedside screening for CAN were included and underwent 2 standardized autonomic testings using 4 standardized tests (deep breathing, Valsalva maneuver, 30/15 ratio, and changes in blood pressure during standing), separated by 3 ± 1 years. …”
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A new distal radius fracture classification depending on the specific fragments through machine learning clustering method by Yuling Gao, Yanrui Zhao, Yang Liu, Shan Lei, Hanzhou Wang, Yuerong Lizhu, Tianchao Lu, Zhexian Cheng, Dong Wang, Binzhi Zhao, Ziyi Li, Junlin Zhou

“…There were no differences in the postoperative radiograph parameters, functional outcomes and incidences of complications for each type of volar side group and dorsal side group except that the 3.2 type DRFs showed less range of flexion (75.56±7.48)° and extension (61.65±9.9)° than other dorsal types. Conclusions A new intra-articular distal radius fractures classification was proposed based on the affection condition of volar or dorsal side. …”
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Relationship Between Sleep Time and Depressive Symptoms in Middle-Aged and Elderly Chinese: Mediating Role of Body Pain by Yang Z, Li B, Ma D, Lv Y, Qiu X, Zhang W, Wang J, Zhang Y, Xu C, Deng Y, Li J, Zhen X, Zhang J

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Anatomic characteristics of the lacrimal sac and adjacent bony structures–a computed tomographic-dacryocystography research by Xin-Han Cui, Yan-Wen Fang, Li-Min Zhang, Ji-Ni Qiu, Chao-Ran Zhang, Yan Wang

“…RESULTS: The height of the lacrimal sac was 12.99±2.10 mm in this study. The operculum of the middle turbinate (OMT) was located vertically in the lower third of the lacrimal sac. …”
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Incidence and survival of skin melanoma in Puglia: A comparison with the rest of Italy by Anna Maria Nannavecchia, Danila Bruno, Antonino Ardizzone, Enrico Caputo, Anna Melcarne, Antonia Mincuzzi, Fernando Palma, Lucia Bisceglia, Ida Galise, Francesco Cuccaro

“…Results: Age-adjusted incidence rates per 100,000 inhabitants in males were: Puglia 9.9 (95% confidence interval [CI] 9.1 to 10.8), AIRTUM Italy (AIRTUM pool) 12.0 (95% CI 11.6 to 12.4), Pool of Southern Italian registries (South pool) 7.1 (95% CI 6.6 to 7.6); in females: Puglia 9.7 (95% CI 8.9 to 10.6), AIRTUM pool 11.3 (95% CI 10.9 to 11.7), South pool 6.5 (95% CI 6.0 to 7.0). …”
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Detection of atrial fibrillation in primary care with radial pulse palpation, electronic blood pressure measurement and handheld single-lead electrocardiography: a diagnostic accur... by Wim A M Lucassen, Henk C P M van Weert, Bjorn Winkens, Henri E J H Stoffers, J André Knottnerus, Steven B Uittenbogaart, Nicole Verbiest-van Gurp, Petra M G Erkens

“…All negative predictive values were ≥99.7%.Conclusion In detecting AF, electronic blood pressure measurement (WatchBP Home A), but especially handheld ECG (MyDiagnostick) showed better diagnostic accuracy than radial pulse palpation.Trial registration number Netherlands Trial Register No. …”
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Prevalensi dan Tingkat Resistansi Silang Golongan Kuinolon Pada Escherichia coli Asal Usap Kloaka Ayam Layer by Nur Nur Hidayah, Maria Fatima Palupi, Novida Ariyani Ariyani, Indryana Indryana Indryana, Anna Miftahul Jannah, Siti Komariyah Komariyah, Rosana Anita Sari, Ambarwati Ambarwati Ambarwati, Emi Rusmiati Rusmiati, Nafisah Idrishanty Idrishanty, Fika Asti Fanani

“…Nilai (k) resistansi silang siprofloksasin terhadap empat kuinolon yang lain adalah 0,86-0,99. Hal ini menunjukkan  tingginya resistansi silang dalam golongan kuinolon. …”
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Assessing the validity and reliability of the Indonesian version of Patient-Reported Outcomes Measurement Information System (PROMIS) Global Health Scale v1.2 by Vitriana Biben, Farida Arisanti, Efi Fitriana, Erika Maklun, Vindy Margaretha Miguna, Nabilla Fikria Alviani

“…Structural validity results were χ2/df (1.53), RMSEA (0.04), RMR (0.03), and CFI (0.99). The reliability results showed that Cronbach's Alpha for Global Physical Health (GPH) and Global Mental Health (GMH) was 0.61 and 0.77, respectively. …”
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Optimization of Lactic Acid Production from Pineapple By-Products and an Inexpensive Nitrogen Source Using Lactiplantibacillus plantarum strain 4O8 by Joel Romial Ngouénam, Pierre Marie Kaktcham, Chancel Hector Momo Kenfack, Edith Marius Foko Kouam, François Zambou Ngoufack

“…A pineapple by-product concentration of 141.75 g/l, a nitrogen source volume of 108.99 ml/l, and a temperature of 30.89°C were recorded as the optimum conditions for LA production. …”
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Factors Associated with HIV Testing among Male Students Who Have Engaged in Sexual Behaviour in Zhejiang Province, China by Zhongrong Yang, Hui Wang, Qiaoqin Ma, Weiyong Chen, Xiang Zhao, Tingting Jiang, Wanjun Chen, Xin Zhou, Lin Chen

“…The results of multivariate analysis demonstrated that the participants who were in the junior grade level (adjusted odds ratio (AOR) = 1.59, 95% confidence interval (95% CI): 1.10–2.30) exhibited acceptance to male homosexual behaviour (AOR = 1.73, 95% CI: 1.19–2.52), had been exposed to testing publicity in the previous year (AOR = 1.51, 95% CI: 1.06–2.15), had been exposed to self-risk assessment for HIV infection (AOR = 2.66, 95% CI: 1.99–3.55), had male or bisexual partners (AOR = 1.60, 95% CI: 1.05–2.46), had a score for the scale indicating awareness of different testing methods between 2 and 5 (AOR = 2.19, 95% CI: 1.51–3.16) or greater than 6 (AOR = 1.49, 95% CI: 1.01–2.66), and had a score for the scale indicating knowledge of different testing facilities between 3 and 5 (AOR = 1.63, 95% CI: 1.00–2.66) were inclined to engage in HIV testing. …”
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Causal association between matrix metalloproteinases and diabetic neuropathy: a two-sample Mendelian randomization study by Chao Bai, Chao Bai, Wenwen Yang, Guangwei Qi, Liuyu Yang, Qingrui Wu, Jieguang Peng, Ning Wang, Tao Liu

“…To evaluate the analysis’ heterogeneity and potential pleiotropy, sensitivity examinations including MR-PRESSO analysis, Cochran’s Q test, and the leave-one-out test were conducted.ResultsIVW analysis revealed that genetically decreased serum MMP-2 level were causally associated with a high risk of DN (OR = 0.88, 95% CI: 0.79-0.99, P = 0.026). Genetically elevated serum MMP-16 level were causally associated with a high risk of DN (OR = 1.15, 95% CI: 1.01-1.32, P = 0.038). …”
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Maternal Uterine Artery Doppler and Serum Marker in the First Trimester as Predictive Markers for Small for Gestational Age Neonates and Preeclampsia: A Pilot Study by Je Yeon Lee, Kyung A Lee, So Yun Park, Soo Jung Kim, So-Yeon Shim, Young Ju Kim, Mi Hye Park

“…Regardless of whether a notch was present in the second trimester, a uterine artery notch in the first trimester was associated with an excellent negative predictive value (99.6%) for PE. <b>Conclusions</b>: This study suggests the clinical importance of assessing serum beta-hCG and the uterine artery notch in the first trimester to predict SGA and PE.…”
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Universal health coverage for women of reproductive ages: a survey-based comprehensive assessment of service utilisation and health expenditure in Tanzania by Jim Todd, Ties Boerma, Peter Binyaruka, Mark Urassa, Milly Marston, Sophia Adam Kagoye, Charles Mangya, Coleman Kishamawe

“…Coverage of antenatal (99.5%) and institutional delivery care (88%) were high; 7.3% of women reported at least one outpatient visit in the last 4 weeks, of which 81% were for their own non-maternal healthcare; 9.3% had been admitted to a hospital during the last year, and 74% of these admissions were for deliveries. …”
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倾向评分法评估Sutureless 技术治疗完全性肺静脉 异位引流的效果 by 高向民, 聂志强, 欧艳秋, 何标川, 袁海云, 曲艳吉, 刘小清

“…匹 配后，Sutureless组中位数体外循环时间87（74.5 ~ 103.0）min少于传统手术组99（76.5 ~ 123.5）min（P = 0.030）；Sutureless组 中位数主动脉阻断时间43（35 ~ 54.5）min 少于传统手术组55（40.5 ~ 705）min（P < 0.001）；复合事件发生率Sutureless 组 6.8%（5/73）显著低于传统手术组24.7%（18/73），HR的95%CI = 0.20（0.06 ~ 0.61），P = 0.005。…”
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基于红外相机技术的南滚河国家级自然保护区鸟兽多样性初步监测 by 陈彦一, 肖剑平, 王志胜, 陈德明, 李 旭

“…</i>调查到的兽类中相对丰富度最高的为赤麂<i>(Muntiacus vaginalis</i>,<i>I</i>_RA=10.19),其次是野猪(<i>Sus scrofa</i>,<i>I</i>_RA=9.25)、水鹿(<i>I</i>_RA=4.42)、黄鼬(<i>Mustela sibirica</i>,<i>I</i>_RA=2.36); 鸟类中相对丰富度最高的为白尾蓝地鸲(<i>Myiomela leucurum</i>,<i>I</i>_RA=2.34),其次是白鹇(<i>I</i>_RA=1.99)、紫啸鸫(<i>Myophonus caeruleus</i>,<i>I</i>_RA=1.24)、红原鸡(<i>I</i>_RA=0.75)。…”
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Machine learning-based modelling and analysis of carbonation depth of recycled aggregate concrete by Xuyong Chen, Xuan Liu, Shukai Cheng, Xiaoya Bian, Xixuan Bai, Xin Zheng, Xiong Xu, Zhifeng Xu

“…The results show that the extreme gradient boosting (XGB) model exhibited the highest accuracy with an R² of 0.99 and a mean absolute percentage error (MAPE) of 6.632 on the training set, and an R² of 0.953 and a MAPE of 13.243 on the test set. …”
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Prevalence of Hepatitis C Virus Among Hospitalized Patients in a Tertiary Hospital in Italy: The Basis for a National Screening Assessment Model? by Giulia Morsica, Massimo Locatelli, Gema Hernandez-Ibarburu, Francesca Rusconi, Alba Segovia-Hilara, Davide Di Napoli, Matteo Moro, Salvatore Mazzitelli, Hamid Hasson, Federico Esposti, Roberts Mazzuconi, Antonella Castagna

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