A posterior probability approach for gene regulatory network inference in genetic perturbation data by William Chad Young, Adrian E. Raftery, Ka Yee Yeung

“…We propose a fast, simple method for inferring regulatory relationships between genes from knockdown experiments in the NIH LINCS dataset by calculating posterior probabilities, incorporating prior information. …”
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Cytotoxicity of Alkyl Derivatives of Protocetraric Acid by Danielle Bogo, Glaucia Alcantara, Ana Camila Micheletti, Neli Honda, Maria de Fátima Cepa Matos

“…In this work, we evaluated through the sulforhodamine B (SRB) assay the cytotoxic activity of seven alkyl ether derivatives of protocetraric acid (9´-O-alkyl protocetraric acid) against the following cell lines: HT-29 (colon carcinoma), 786-0 (kidney carcinoma), MCF7 (breast carcinoma), HEP2 (laryngeal carcinoma), PC-03 (prostate carcinoma), B16F10 (murine melanoma), UACC-62 (human melanoma), and NIH/3T3 (mouse embryonic fibroblast).  Most compounds were cytotoxic to tested cells, with GI50 < 100.0 μM, and did not show selectivity over them. …”
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Using Time Deformation to Filter Nonstationary Time Series with Multiple Time-Frequency Structures by Mengyuan Xu, Wayne A. Woodward, Henry L. Gray

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Presynaptic CRF1 Receptors Mediate the Ethanol Enhancement of GABAergic Transmission in the Mouse Central Amygdala by Zhiguo Nie, Eric P. Zorrilla, Samuel G. Madamba, Kenner C. Rice, Marissa Roberto, George Robert Siggins

“…A CRF1 (but not CRF2) KO construct and the CRF1-selective nonpeptide antagonist NIH-3 (LWH-63) blocked the augmenting effect of both CRF and ethanol on evoked IPSCs. …”
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Funding for research on cryptococcal disease: an analysis based on the G-finder report by Iraine Duarte, Marcio L. Rodrigues

“…The US National Institutes of Health (NIH) was the main funder, followed by the UK's Wellcome Trust. …”
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G-Filtering Nonstationary Time Series by Mengyuan Xu, Krista B. Cohlmia, Wayne A. Woodward, Henry L. Gray

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Building a Digital Health Research Platform to Enable Recruitment, Enrollment, Data Collection, and Follow-Up for a Highly Diverse Longitudinal US Cohort of 1 Million People in the... by Dave Klein, Aisha Montgomery, Mark Begale, Scott Sutherland, Sherilyn Sawyer, Jacob L McCauley, Letheshia Husbands, Deepti Joshi, Alan Ashbeck, Marcy Palmer, Praduman Jain

“…MethodsWe collaborated with community members, health care provider organizations (HPOs), and NIH leadership to design, build, and validate a secure, feature-rich digital platform to facilitate multisite, hybrid, and remote study participation and multimodal data collection in AOU. …”
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Descemet Endothelial Thickness Comparison Trial 1 (DETECT 1): outcome masked, placebo-controlled trial comparing two types of corneal transplant surgeries and effect of rho kinase... by Thomas M Lietman, Jennifer Rose-Nussbaumer, Bennie H Jeng, Benjamin F Arnold, Winston Chamberlain, Charles C Lin, Jennifer Y Li, William Gensheimer, Jameson Clover, Nicole Varnado, Sarah Abdelrahman

“…Dissemination of findings through peer-reviewed publications and national/international meetings will facilitate knowledge translation and guide clinical practice in the field of corneal transplantation.Ethics and dissemination A data and safety monitoring committee (DSMC) has been empaneled by the NEI.All study protocols will be subject to review and approval by WCG IRB as the single IRB of record.This study will comply with the National Institute of Health (NIH) Data Sharing Policy and Policy on the Dissemination of NIH-Funded Clinical Trial Information and the Clinical Trials Registration and Results Information Submission rule. …”
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Development of malaria diagnosis with convolutional neural network architectures: a CNN-based software for accurate cell image analysis. by Emrah ASLAN

“…The studies were carried out using the Malaria Dataset supplied by the National Institute of Health (NIH), and our proposed architecture was shown to function with 99.12% accuracy. …”
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The normal cell proliferation and wound healing effect of polysaccharides from Ganoderma amboinense by Shuangzhi Zhao, Ming Lei, Hui Xu, Hailun He, Alexander Suvorov, Junhua Wang, Jiying Qiu, Qingxin Zhou, Jinyu Yang, Leilei Chen

“…The wound healing effect of GAMPS (0.1 μg/μL) was obvious on NIH/3T3 and 3.75 μg/μL of GAMPS showed the strongest total antioxidant ability. …”
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Understanding factors that influence whether a woman will seek care for reproductive health: A national survey by Pooja Kanyadan, Latha Ganti, Rohan Mangal, Thor Stead, Lindsey Hahn, Marcos Sosa

“…Thirteen survey questions were designed, some of which were adapted from the NIH Healthcare Access and Utilization Survey. This study found that women of minority races (African American and Hispanic) were more likely to report that they didn’t feel like they were asked for their opinions about their healthcare. …”
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c-myb 反义RNA 重组载体构建及其包装细胞株的建立 by 马会慧, 姚集鲁, 李　刚, 姚春斓, 陈雪娟, 杨绍基

“…采用DOTAP 法将重组逆转录病毒载体转入包 装细胞, 以NIH3T3 细胞为靶细胞测定产病毒滴度。【结果】序列测定结果与GenBank 中序列一致。c-myb 基因片段已定向 克隆入pDOR。…”
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Poorly Differentiated Uterine or Cervical Sarcoma in a Young Dog by Michelle C. Cora, Jennifer A. Neel

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Exploring computational thinking, executive functions, visuospatial skills and experiences with toys in early childhood: Protocol for a controlled trial by Carolina Robledo-Castro, Camilo Vieira Mejía, Jennifer Chiu

“…To assess executive functions and visuospatial skills, standardized and validated neuropsychological measures will be used, including the Flanker task, the NIH Toolbox Card Sorting Test, the Corsi Block Test, the NEPSY-II Mental Rotation Test, the Pyramid of Mexico from the ENI-2 battery, and the Computational Thinking Test (CTt). …”
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HSV-TK 基因逆转录病毒重组体的构建和鉴定 by 谢文练　梁正东　吕　凌

“…摘　要　利用逆转录病毒载体pLNSX 构建了带HSV-TK 基因的逆转录病毒重组体pLNS - TK ,用磷酸钙沉淀法 转染PA317 包装细胞, 经G418 筛选抗性克隆, 建立了产生重组病毒的载体产生细胞系PA317/ TK, 用NIH3T3 细胞测 定病毒(CFU)滴度为3 ×108 L-1。提取PA 317/ TK 细胞的DNA 和细胞上清液的RNA, 在特异性引物引导下, 分别用 PCR 和RT-PCR检测证实PA317/ TK 细胞整合了HSV-TK 基因并产生重组病毒, 为HSV-TK 基因治疗恶性肿瘤的实 验研究打下了基础。…”
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The Impact of Mild Stroke on Participation in Physical Fitness Activities by Mary Hildebrand, Megan Brewer, Timothy Wolf

“…We used data from the Cognitive Rehabilitation and Research Group to examine changes in moderate to high intensity physical activity participation in persons who had a mild stroke as defined by an NIH Stroke Scale score of less than 6 (N=127). …”
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Chronic Inflammatory Demyelinating Polyneuropathy with Atypical Symptoms: A Rare Case of Tongue Fasciculation and Facial Muscle Weakness by Shafiq ur Rehman, Saba Zaidi, Mahzareen

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The Extracellular Matrix Contributes to Mechanotransduction in Uterine Fibroids by Phyllis C. Leppert, Friederike L. Jayes, James H. Segars

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Timp2 loss-of-function mutation and TIMP2 treatment in a murine model of NSCLC: Modulation of immunosuppression and oncogenic signaling by David Peeney, Sarvesh Kumar, Tej Pratap Singh, Yueqin Liu, Sandra M. Jensen, Ananda Chowdhury, Sasha Coates-Park, Joshua Rich, Sadeechya Gurung, Yu Fan, Daoud Meerzaman, William G. Stetler-Stevenson

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Comparison Of Outcome And Side Effects Profile Of Treatment Of Overactive Bladder With Different Classes Of Drugs by Nazish Sarfraz, Humera Akram, Afroza Abbas, Sadaf Shaheen, Zoobia Ashiq Awan, Eesha Yaqoob

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