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Blood biomarkers for vascular cognitive impairment based on neuronal function: a systematic review and meta-analysis
Published 2025-02-01“…Our findings reveal that peripheral Aβ42, Aβ42/Aβ40 ratio, NfL, and S100B significantly differ between VCI and non-VCI groups, indicating their potential as blood biomarkers for VCI.…”
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Blood-based biomarkers in mild behavioral impairment: an updated overview
Published 2025-02-01“…In this context, MBI has been associated with lower plasma Aβ42/Αβ40 ratio, higher plasma phosphorylated tau at threonine 181 (p-tau181), increased neurofilament light chain (NfL) levels, as well as disturbances in metabolic markers, including homocysteine, insulin and ferritin, suggesting a multifaceted neurobiological basis for this syndrome. …”
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Single-cell RNA sequencing highlights the role of distinct natural killer subsets in sporadic amyotrophic lateral sclerosis
Published 2025-01-01“…We analyzed differences in the proportions of PBMC, gene expression, and cell-cell communication patterns between ALS patients and HC, as well as their association with plasma neurofilament light (NfL) concentrations, a surrogate biomarker for neurodegeneration. …”
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Exploring cognitive and neuroimaging profiles of dementia subtypes of individuals with dementia in the Democratic Republic of Congo
Published 2025-02-01“…Core AD biomarkers (Aβ42/40 and p-tau181) and non-specific neurodegeneration biomarkers (NfL, GFAP) were measured in blood plasma. Neuroimaging structures were assessed using magnetic resonance imaging (MRI). …”
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An interpretable machine learning tool for in-home monitoring of agitation episodes in people living with dementia: a proof-of-concept studyResearch in context
Published 2025-02-01“…M.B. and A.K.S. are funded by the UK Dementia Research Institute [award number UKDRI-7002 and UKDRI-5209]. N.F.L., A.C., C.W. and S.K. are funded by the UK Dementia Research Institute [award number UK DRI-7002].…”
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