Construction and Comparison of Machine Learning-Based Risk Prediction Models for Major Adverse Cardiovascular Events in Perimenopausal Women by Chen A, Chang X, Bian X, Zhang F, Ma S, Chen X

“…Major adverse cardiovascular events (MACE) are the combination of clinical events including heart failure, myocardial infarction and other cardiovascular diseases. …”
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Catlet scoring system as a new predictor for in-stent restenosis in patients with chronic coronary artery disease undergoing percutaneous coronary intervention with drug-eluting st... by Juan Wang, Mingchao Zhang, Weipeng Gan, Mingxing Xu, JiaYan Zhou, Lingfei Yang, Yongsheng Ke

“…Preliminary studies have demonstrated its superiority over the the Synergy between percutaneous coronary intervention with Taxus and Cardiac Surgery (SYNTAX) score with respect to outcome predictions for acute myocardial infarction (AMI) patients. However, there are fewer studies on the prognostic in chronic coronary artery disease(CAD). …”
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E-HEART score: A novel scoring system for undifferentiated chest pain in the emergency department by V. Yuvaraj, Sachin Sujir Nayak, S. Vimal Krishnan

“…The accuracy of the E-HEART score was compared with other conventional risk stratification scoring systems such as the thrombolysis in myocardial infarction (TIMI), history, electrocardiogram, age, and risk factors, Troponin Only Manchester ACS (T-MACS), and HEART scores. …”
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Revealing the limitations of 10-year MACE observations: 20-year observed total cardiovascular burden in the EPIC-Norfolk study by Frank LJ Visseren, Harald T Jorstad, Marjolein Snaterse, S Matthijs Boekholdt, Tinka J van Trier, Jannick AN Dorresteijn, Manon van den Bogaart, Wilma JM Scholte op Reimer, Ron JG Peters

“…Therefore, we aimed to quantify how well 10-year observed incidence reflects 20-year observed incidence and how MACE reflects total CVD events across demographic groups, using observations in long-term prospective data.Methods In individuals aged 40–79 without CVD or diabetes from the population-based EPIC-Norfolk cohort, we compared the first occurrence of 10 and 20 years (1) 3-point MACE events (non-fatal myocardial infarction+non-fatal stroke+fatal CVD) and (2) total CVD events (all non-fatal and fatal CVD events leading to hospitalisation), stratified by sex and age.Results Among 22 569 participants (57% women), incident 10-year and 20-year 3-point MACE was 5.3% and 15.5%, respectively, yielding 20/10 year ratios from 2.2 (in older men) to 4.5 (in younger women). …”
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TRPV1 Activation Attenuates High-Salt Diet-Induced Cardiac Hypertrophy and Fibrosis through PPAR-δ Upregulation by Feng Gao, Yi Liang, Xiang Wang, Zongshi Lu, Li Li, Shanjun Zhu, Daoyan Liu, Zhencheng Yan, Zhiming Zhu

“…Transient receptor potential vanilloid type 1 (TRPV1), a specific receptor for capsaicin, exerts a protective role in cardiac remodeling that resulted from myocardial infarction, and peroxisome proliferation-activated receptors δ (PPAR-δ) play an important role in metabolic myocardium remodeling. …”
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Enhanced Generation of Human Induced Pluripotent Stem Cells from Peripheral Blood and Using Their Mesoderm Differentiation Ability to Regenerate Infarcted Myocardium by Ju-Young Kim, Han-Mo Yang, Joo-Eun Lee, Mika Jeon, Sang-Bum Bang, Jihye You, Joonoh Kim, Jaewon Lee, Jin Hur, Hyo-Soo Kim

“…In contrast, histone H3 lysine 9 acetylation was downregulated during the differentiation process of the CiMS-iPSCs. In the myocardial infarction model, the CiMS-iPSCs group showed more therapeutic potential in regenerating the myocardium than other cell types. …”
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Relationship between the ST-Segment Resolution and Microvascular Dysfunction in Patients Who Underwent Primary Percutaneous Coronary Intervention by Byung Gyu Kim, Sung Woo Cho, Jeong-Ha Ha, Hyo Seung Ahn, Hye Young Lee, Gwang Sil Kim, Young Sup Byun, Kun Joo Rhee, Jong Chun Nah, Byung Ok Kim

“…A total of 73 consecutive patients with ST-segment elevation myocardial infarction (STEMI) who underwent successful PPCI were evaluated. …”
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The Impact of Complete Revascularization in Symptomatic Severe Left Ventricular Dysfunction between Coronary Artery Bypass Graft and Percutaneous Coronary Intervention by Hsiu-Yu Fang, Yen-Nan Fang, Yin-Chia Chen, Jiunn-Jye Sheu, Wei-Chieh Lee

“…The patients (N = 236) who were diagnosed with dilated cardiomyopathy or valvular heart disease without coronary artery stenosis, those with prior history of CABG or valvular surgery (N = 59), those who presented ST-segment elevated myocardial infarction (STEMI), those with a CAD and SYNTAX score of  ≦ 22 (N = 175), those who received emergent CABG for coronary perforation (N = 3), and those who had NYHA class ≦ 2 (N = 65) were excluded. …”
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CD137 Signaling Promotes Endothelial Apoptosis by Inhibiting Nrf2 Pathway, and Upregulating NF-κB Pathway by Tianxin Geng, Yang Yan, Yue Zhang, Liangjie Xu, Guangyao Zang, Jin Chuan Yan

“…Serum samples were collected from 11 patients with acute myocardial infarction and 4 controls. Peritoneal injection of agonist-CD137 recombinant protein in ApoE−/− mice was used to determine whether CD137 signaling can promote apoptosis in vivo, and human umbilical vein endothelial cells treated with agonist-CD137 recombinant protein, M5580 (a Nrf2 pathway agonist) and CAPE (a NF-κB pathway inhibitor) were used to explore the effect of Nrf2 and NF-κB pathway in CD137 signaling-induced ECs apoptosis in vitro. …”
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Arterial Thromboembolism in Patients With Advanced Lung Cancer: Secondary Analyses of the Rising‐VTE/NEJ037 Study by Naoki Furuya, Yukari Tsubata, Takamasa Hotta, Toshihide Yokoyama, Masahiro Yamasaki, Nobuhisa Ishikawa, Kazunori Fujitaka, Tetsuya Kubota, Kunihiko Kobayashi, Takeshi Isobe

“…The most common location for ATE was cerebral infarction (N = 31, 75.6%), followed by myocardial infarction (N = 4, 9.8%). Multivariate analysis determined the incidence of VTE, D‐dimer, a comorbidity of atrial fibrillation, and four other factors as independent risk factors of ATE. …”
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Association between normal weight obesity and comorbidities and events of cardiovascular diseases among adults in South China. by Miaomiao Ma, Deliang Lv, Xiaobing Wu, Yuqing Chen, Shimiao Dai, Yutian Luo, Hui Yang, Wei Xie, Fengzhu Xie, Qinggang Shang, Ziyang Zhang, Zhiguang Zhao, Ji-Chang Zhou

“…The cardiovascular comorbidities being studied were abdominal obesity (AO), diabetes, hypertension, dyslipidemia, metabolic syndrome, and chronic kidney disease, while the CVD events were occurrences of myocardial infarction and strokes. Questionnaire surveys, physical examinations, and laboratory tests were performed. …”
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Diabetes Complications at Presentation and One Year by Glycated Haemoglobin at Diagnosis in a Multiethnic and Diverse Socioeconomic Population: Results from the South London Diabet... by Mohsin Azam, Lindsey Marwood, Khalida Ismail, Tyrrell Evans, Sobha Sivaprasad, Kirsty Winkley, Stephanie Anne Amiel

“…At recruitment and one year, there were no between-group differences in the prevalence of diabetic complications, except that those diagnosed with HbA1c<48 mmol/mol had more sensory neuropathy at recruitment (p=0.039) and, at one year, had new myocardial infarction (p=0.012) but less microalbuminuria (p=0.012). …”
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Diabetic retinopathy further increases risk of cardiovascular disease mortality in a high-risk cohort by Richard Kha, Yasemin Kapucu, Mayuri Indrakumar, George Burlutsky, Aravinda Thiagalingam, Pramesh Kovoor, Paul Mitchell, Gerald Liew

“…After controlling for age, sex, BMI, diabetes, total cholesterol, smoking status, hypertension, previous myocardial infarction and stroke, any DR was associated with 1.8-fold higher risk of CVD mortality (Hazard Ratio [HR] 1.84, 95% Confidence Interval [95% CI: 1.30–2.61]). …”
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Impact of Acute Myocardial Injury on Short‐ and Long‐Term Outcomes in Patients With Primary Intracerebral Hemorrhage by Shenghui Ma, Jiawen Li, Qi Kong, Zhiming Xu, Haojie Wu, Yujia Jin, Xianghua Ye, Dong Luo, Lusha Tong, Feng Gao

“…The fourth Universal Definition of Myocardial Infarction introduced for the first time the criteria for acute myocardial injury (AMI). …”
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Knowledge, attitudes, and beliefs regarding acute coronary syndrome in patients with type 2 diabetes: a cross-sectional study by Mohammad Amerzadeh, Mahdie Bahrami, Mojtaba Senmar, Zahra Hosseinkhani, Zahra Shafiei Kisomi

“…Inclusion criteria included a willingness to participate in the study, mental health status (based on existing records), and no history of myocardial infarction (MI). Data collection tools comprised a demographic questionnaire and the ACS Response questionnaire. …”
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Adherence to guidelines for creatinine and potassium monitoring and discontinuation following renin–angiotensin system blockade: a UK general practice-based cohort study by Henrik Toft Sørensen, Liam Smeeth, Dorothea Nitsch, Morten Schmidt, Laurie A Tomlinson, Krishnan Bhaskaran, Kathryn E Mansfield

“…Although patients with prior myocardial infarction, hypertension or baseline potassium &gt;5 mmol/L were at high risk of ≥30% increase in creatinine after ACEI/ARB initiation, there was no evidence that they were more frequently monitored.Conclusions Only one-tenth of patients initiating ACEI/ARB therapy receive the guideline-recommended creatinine monitoring. …”
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Cardiovascular Profile and Cardiovascular Imaging After Bariatric Surgery: A Narrative Review by Mihaela Toader, Liliana Gheorghe, Costin Chirica, Ionuț-Alexandru Ghicu, Sabina-Ioana Chirica, Andreea Isabela Mazga, Danisia Haba, Mădălina Maxim, Ancuța Andreea Miler, Daniela Crișu, Mihai Ștefan Cristian Haba, Daniel Vasile Timofte

“…<i>Results</i>: BaS has been found to be strongly associated with a reduced incidence of severe complications in individuals with a history of myocardial infarction (MI) and severe obesity. Specifically, this procedure is linked to a lower occurrence of major adverse cardiovascular events and a decrease in overall mortality. …”
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Increased indexed proximal aortic diameter is a predictor of poor prognosis in maintenance hemodialysis patients by Junwei Xu, Wenyi Tang, Lizheng Song, Yuxi Huang, Li Xiao, Fangyuan Cheng, Qianglin Guan, Mei Xu, Chuoxin Ma, Jian Chen, Jianting Ke

“…The secondary endpoint was major adverse cardiovascular events (MACE), including cardiovascular mortality, myocardial infarction and stroke. Cox proportional hazards models were conducted to evaluate the association between baseline ARD/BSA and clinical outcomes.Results A total of 391 patients were included in this study. …”
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Percutaneous coronary intervention supported by intra-aortic balloon pump in treating one case of cardiogenic shock and related integrated nursing of traditional Chinese and wester... by WANG Zhaojia (王兆嘉), LI Xiao (李霄), LIU Shanshan (刘珊珊), ZHANG Lina (张丽娜), ZHANG Nan (张楠), TANG Ling (唐玲)

“…This paper summarized the integrated nursing of traditional Chinese and western medicine for a patient undergoing percutaneous coronary intervention (PCI) supported by intra-aortic balloon pump(IABP) for cardiogenic shock acute caused by anterior myocardial infarction. Key issues of nursing included symptomatic nursing, acupoint application, auricular point pressing therapy, oral care with Chinese herbal medicine were carried during the treatment period. …”
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Cardiac CT reveals high prevalence of coronary artery disease in esophageal cancer eligible for radiotherapy by Akinori Takada, Satoshi Nakamura, Yutaka Toyomasu, Takamitsu Mase, Tomoko Kawamura, Suguru Araki, Yoshitaka Suzuki, Masaki Ohi, Hajime Sakuma, Yoshihito Nomoto, Kakuya Kitagawa

“…Late enhancement, indicating myocardial infarction, was observed in seven patients (17%). …”
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