Primary Terminal Haemochromatosis in a 50 Year-Old Patient by M. I. Gonik, M. S. Zharkova, O. Yu. Kiseleva, E. V. Berezina, Sh. A. Ondos, Yu. V. Lerner, E. A. Kogan, V. T. Ivashkin

“…Echocardiographic evidence of dilated cardiomyopathy of all chambers, a reduced 24% ejection fraction at absent acute myocardial infarction. Primary haemochromatosis was suspected upon high ferritin, transferrin iron saturation and multiple organ dysfunction. …”
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Epidemiological characteristics of stroke incidence from 2017 to 2022 in Songjiang District, Shanghai by SU Xuyan, WANG Yuzhuo, WU Yiling, HE Jingyi, YANG Peng, LANG Dongchen, JIANG Yonggen, ZHAO Genming, ZHENG Yang

“…ObjectiveTo investigate the prevalence of stroke in Songjiang District from 2017 to 2022, to analyze the epidemiological characteristics of stroke incidence, so as to provide a scientific basis for the formulation of stroke prevention and control policies.MethodsData of new stroke incidence from 2017 to 2022 in Songjiang District were obtained from the Shanghai Stroke and Acute Myocardial Infarction Registration and Reporting Information System. …”
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Association of β-Blocker Therapy at Discharge with Clinical Outcomes after Acute Coronary Syndrome in Patients without Heart Failure by Yan Chen, Xiao-fang Tang, Run-lin Gao, Yue-jin Yang, Bo Xu, Jin-qing Yuan

“…During a 2-year follow-up, no significant association was observed of β-blocker use with all-cause mortality (with β-blockers 47/5,043 (0.9%) vs. without β-blocker use 8/588 (1.4%); hazard ratio (HR) 0.762, 95% confidence interval 0.36 to 1.64; P=0.485), cardiac death, myocardial infarction (MI), or major adverse cardiovascular and cerebrovascular events. …”
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Risk Factors for Coronary Events After Robotic Hybrid Off-Pump Coronary Revascularization by Aleksander Dokollari, Beatrice Bacchi, Serge Sicouri, Francesco Cabrucci, Massimo Bonacchi, Danielle Spragan, Mary Ann C. Wertan, Nitin Ghorpade, Stephanie Kjelstrom, Georgia Montone, Yoshiyuki Yamashita, Basel Ramlawi, Francis Sutter

“…Objectives: The impact of long-term complications after robotic hybrid coronary revascularization (HCR), including persistent angina, repeat revascularization, and myocardial infarction (MI), remains limited. This study aims to determine the risk factors for coronary events after robotic HCR and their time-varying effects on outcomes. …”
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Relationship Between Myocardial Strain and Extracellular Volume: Exploratory Study in Patients with Severe Aortic Stenosis Undergoing Photon-Counting Detector CT by Costanza Lisi, Victor Mergen, Lukas J. Moser, Konstantin Klambauer, Jonathan Michel, Albert M. Kasel, Hatem Alkadhi, Matthias Eberhard

“…Patients with prior myocardial infarction (<i>n</i> = 6) had reduced median global longitudinal strain values (−9.1% versus −21.7%, <i>p</i> < 0.001) but no significant differences in global mid-myocardial ECV (<i>p</i> > 0.05). …”
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Stemness Maintenance Properties in Human Oral Stem Cells after Long-Term Passage by Francesca Diomede, Thangavelu Soundara Rajan, Valentina Gatta, Marco D’Aurora, Ilaria Merciaro, Marco Marchisio, Aurelio Muttini, Sergio Caputi, Placido Bramanti, Emanuela Mazzon, Oriana Trubiani

“…Neural crest-derived mesenchymal stem cells (MSCs) from human oral tissues possess immunomodulatory and regenerative properties and are emerging as a potential therapeutic tool to treat diverse diseases, such as multiple sclerosis, myocardial infarction, and connective tissue damages. In addition to cell-surface antigens, dental MSCs express embryonic stem cell markers as neural crest cells originate from the ectoderm layer. …”
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Efficacy and Safety of Dual Antiplatelet Therapy in Patients Undergoing Coronary Stent Implantation: A Systematic Review and Network Meta-Analysis by Yi Xu, Yimin Shen, Delong Chen, Pengfei Zhao, Jun Jiang

“…Primary endpoints were all-cause mortality, cardiac death, myocardial infarction (MI), major bleeding, any bleeding, definite or probable stent thrombosis (ST), and net adverse clinical events (NACE). …”
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Role of Cardiac Magnetic Resonance Imaging in Detecting Myocardial Viability in Patients with Chronic Ischaemic Heart Disease: A Prospective Observational Study by Subhosree Dey, Parul Dutta, Bornali Dutta, Baloy Jyoti Talukdar, Sushant Agarwal, Dhiraj Baruah

“…The assessment of myocardial viability using Contrast-enhanced Magnetic Resonance Imaging (CE-MRI) has become a quintessential imaging method for the guidance of treatment in patients with Myocardial Infarction (MI). Aim: To assess cardiac morphology, function, perfusion and myocardial viability in patients with chronic ischaemic heart disease, and to stratify patients into conservative and operative management based on the myocardial viability. …”
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The Optimal Intervention Time of Bone Marrow Mesenchymal Stem Cells in Ameliorating Cardiac Fibrosis Induced by Viral Myocarditis: A Randomized Controlled Trial in Mice by Tingting Wu, Yuan Xie, Jing Huang, Ping Li, Xuliang Wang, Yaoyao Yan, Tianhe Xia, Lei Li, Feng Zhu, Hao Li, Rongzhou Wu

“…Bone marrow-derived mesenchymal stem cells (BMSCs) have recently been introduced to treat cardiovascular diseases, such as myocardial infarction and dilated cardiomyopathy. Nevertheless, there are few researches focused on the application of BMSCs in treating viral myocarditis, not to mention its optimal intervention timer potential mechanisms. …”
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Nicotine dependence is associated with an increased risk of developing chronic, non-communicable inflammatory disease: a large-scale retrospective cohort study by Khalaf Kridin, Khalaf Kridin, Khalaf Kridin, Cristian Papara, Katja Bieber, David A. De Luca, Jan Philipp Klein, Marlene A. Ludwig, Philip Curman, Philip Curman, Philip Curman, Philip Curman, Artem Vorobyev, Astrid Dempfle, Ralf J. Ludwig

“…Using propensity score matching (PSM) to control for age, sex, ethnicity, and other CID risk factors, we contrasted the risk of developing any or any of the 38 CIDs in 881,192 EHRs from individuals with nicotine dependence to PSM-matched unexposed counterparts.ResultsThe analytical pipeline was validated by demonstrating an increased risk of individuals exposed to nicotine dependence for subsequent diagnosis of myocardial infarction, malignant neoplasm of the lung, and chronic obstructive pulmonary disease. …”
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Aspirin modulates generation of procoagulant phospholipids in cardiovascular disease, by regulating LPCAT3 by Majd B. Protty, Victoria J. Tyrrell, Ali A. Hajeyah, Bethan Morgan, Daniela Costa, Yong Li, Anirban Choudhury, Rito Mitra, David Bosanquet, Alex Reed, Iuliia K. Denisenko, Katsuyuki Nagata, Hideo Shindou, Benjamin F. Cravatt, Alastair W. Poole, Takao Shimizu, Zaheer Yousef, Peter W. Collins, Valerie B. O’Donnell

“…Limb or coronary (ST-elevation myocardial infarction, STEMI) thrombi displayed a platelet eoxPL signature while carotid thrombi had a white cell profile. …”
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Clinical Profile and Outcome in Patients with Coronary Slow Flow Phenomenon by Xiaogang Zhu, Hua Shen, Fei Gao, Sijing Wu, Qian Ma, Shuo Jia, Ziwei Zhao, Shan Tong, Zhihao Zhang, Yujie Zhou

“…Two teams (clinical center and core lab) were blind to patient data for the assessment of coronary angiograph using corrected thrombolysis in myocardial infarction (TIMI) frame count (CTFC). The study cohort consisted of 429 patients (294 men, 68.5%), aged from 30 to 78 years (mean, 54 years). …”
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Predictors of long-term symptom burden and quality of life in patients hospitalised with chest pain: a prospective observational study by Tone Merete Norekvål, Jørund Langørgen, Torbjørn Omland, Øyvind Skadberg, Kjell Vikenes, Nasir Saeed, Ole-Thomas Steiro, Hilde Lunde Tjora, Rune Oskar Bjørneklett, Vernon Vijay Singha Bonarjee, Øistein Rønneberg Mjelva, Kristin Moberg Aakre

“…Discharge diagnoses were non-ST elevation myocardial infarction (NSTEMI) (14.2%), UAP (17.1%), non-coronary cardiac disease (6.6%), non-cardiac disease (6.3%) and non-cardiac chest pain (NCCP) (55.6%). …”
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Oxidative Stress, Antioxidant Capacity, and Inflammatory Markers in Patients with Idiopathic Complete Heart Block by Shobhit Shah, Monika Bhandari, Pravesh Vishwakarma, Wahid Ali, Mohammad Kaleem Ahmad, Abhishek Singh, Ayush Shukla, Akhil Kumar Sharma, Gaurav Chaudhary, Akshyaya Pradhan, Sharad Chandra, Rishi Sethi, S. K. Dwivedi

“…Individuals with drug-induced CHB and acute myocardial infarction were not accepted. Results: Out of 60 patients, the gender distribution was 37 men and 23 women, with a mean age of 62.48 ± 7.98 years. …”
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Exosomes Derived from Apelin-Pretreated Mesenchymal Stem Cells Ameliorate Sepsis-Induced Myocardial Dysfunction by Alleviating Cardiomyocyte Pyroptosis via Delivery of miR-34a-5p by Li T, Zhao Y, Cao Z, Shen Y, Chen J, Huang X, Shao Z, Zeng Y, Chen Q, Yan X, Li X, Zhang Y, Hu B

“…Our previous study demonstrated that Apelin pretreatment enhanced the therapeutic benefit of MSCs in myocardial infarction by improving their paracrine effects. …”
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Comparison of biodegradable and durable polymer drug-eluting stents in acute coronary syndrome: a meta-analysis by Tingting Wei, Can Huang, Yifan Zeng, Haoyong Yuan, Zhongshi Wu, Ting Lu, Yalin Liu

“…Safety endpoints included all-cause death, cardiac death, target vessel myocardial infarction and stent thrombosis (ST).Methods We searched PubMed, Medline, Embase and the Cochrane Controlled Register of Trials for comparative studies of BP-DES and DP-DES in patients with ACS from January 2000 to July 2021. …”
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Both Low and High Postprocedural hsCRP Associate with Increased Risk of Death in Acute Coronary Syndrome Patients Treated by Percutaneous Coronary Intervention by Runzhen Chen, Chen Liu, Peng Zhou, Yu Tan, Zhaoxue Sheng, Jiannan Li, Jinying Zhou, Yi Chen, Li Song, Hanjun Zhao, Hongbing Yan

“…Inflammation poses dual effects after myocardial infarction, but robust evidence shows that high-sensitivity C-reactive protein (hsCRP), as an inflammatory marker, is constantly associated with worse outcomes. …”
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Association of Time in Target Range of Resting Heart Rate With Adverse Clinical Outcomes in Patients With Acute Coronary Syndromes After Percutaneous Coronary Intervention by Jianmei Zheng, Cen Chen, Zhongcai Fan, Qiang Ye, Yi Zhong, Jinsong Li, Hao Huang, Jianping Deng, Jinghong Zhao, Tinglin Xiong, Wenjie Tian, Xuemei Zhang

“…MACE was defined as a composite of cardiac death, nonfatal recurrent myocardial infarction, ischemic-driven revascularization, and ischemic stroke. …”
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Cardiovascular outcomes associated with treatment of type 2 diabetes in patients with ischaemic heart failure by Thomas R. Godec, Daniel I. Bromage, Mar Pujades‐Rodriguez, Antonio Cannatà, Arturo Gonzalez‐Izquierdo, Spiros Denaxas, Harry Hemingway, Ajay M. Shah, Derek M. Yellon, Theresa A. McDonagh

“…Abstract Aim The optimal strategy for diabetes control in patients with heart failure (HF) following myocardial infarction (MI) remains unknown. Metformin, a guideline‐recommended therapy for patients with chronic HF and type 2 diabetes mellitus (T2DM), is associated with reduced mortality and HF hospitalizations. …”
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Predictors of late complications after coronary artery bypass grafting in patients with stable coronary heart disease by O.J. Zharinov, К.O. Mikhaliev, O.A. Yepanchintseva, B.M. Todurov

“…In general, 29 late complications (3 cases of heart failure, 3 – first diagnosed atrial fibrillation (AF), 4 – acute coronary syndrome, 11 – left ventricular ejection fraction (LV EF) relative decrease more than 10 %, 2 – formation of atrial fibrillation permanent form, 2 – acute myocardial infarction and 4 deaths) were diagnosed in 24 patients. …”
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