Identifying plasma exosome antigens as a potential diagnostic biomarker for tuberculosis disease by Yan Jiang, Li Yan, Baoru Zhou, Jianming Hong, Huixing Tan, Xiaonan Li, Yong Wang

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Tuberculosis in the incarcerated population by Pablo Cristiano de Souza, Rodrigo de Macedo Couto, Alec Brian Lacerda, Pãmela Rodrigues de Souza Silva, Omar Ariel Espinosa, Jaqueline Costa Lima

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MCL Plays an Anti-Inflammatory Role in Mycobacterium tuberculosis-Induced Immune Response by Inhibiting NF-κB and NLRP3 Inflammasome Activation by Qingwen Zhang, Xinru Jiang, Weigang He, Kailin Wei, Jinxia Sun, Xiangyang Qin, Yuejuan Zheng, Xin Jiang

“…Mycobacterium tuberculosis (Mtb) remains a significant menace to global health as it induces granulomatous lung lesions and systemic inflammatory responses during active tuberculosis (TB). …”
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Different Transcriptional Profiles of Human Monocyte-Derived Dendritic Cells Infected with Distinct Strains of Mycobacterium tuberculosis and Mycobacterium bovis Bacillus Calmette-Guérin by Nunzia Sanarico, Alessia Colone, Manuela Grassi, Viviana Speranza, Daniela Giovannini, Antonio Ciaramella, Vittorio Colizzi, Francesca Mariani

“…In order to analyze dendritic cells (DCs) activation following infection with different mycobacterial strains, we studied the expression profiles of 165 genes of human monocyte-derived DCs infected with H37Rv, a virulent Mycobacterium tuberculosis (MTB) laboratory strain, CMT97, a clinical MTB isolate, Mycobacterium bovis bacillus Calmette-Guérin (BCG), Aventis Pasteur, and BCG Japan, both employed as vaccine against tuberculosis. …”
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Mycobacterium tuberculosis and Dual M. tuberculosis/M. bovis Infection as the Cause of Tuberculosis in a Gorilla and a Lioness, Respectively, in Ibadan Zoo, Nigeria by Aina Adeogun, Olutayo Omobowale, Chiaka Owuamanam, Olugbenga Alaka, Victor Taiwo, Dick van Soolingen, Simeon Cadmus

“…Here, we present cases of Mycobacterium tuberculosis and M. tuberculosis/M. bovis infections in a female gorilla and a lioness, respectively, in a zoo in Ibadan, Nigeria. …”
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Evaluating the Contribution of Nocardia spp. and Mycobacterium tuberculosis to Pulmonary Infections among HIV and Non-HIV Patients at the Komfo Anokye Teaching Hospital, Ghana by Samuel Asamoah Sakyi, Kwabena Owusu Danquah, Richard Dadzie Ephraim, Anthony Enimil, Venus Frimpong, Linda Ahenkorah Fondjo, Esther Love Darkoh

“…Detection of Mycobacterium tuberculosis by fluorescence-based Ziehl–Neelsen staining, culture, and PCR yielded 9 (15%), 11 (18.3%), and 12 (20%), respectively. …”
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Elucidating the knowledge, attitude, and stigma associated with tuberculosis: a community based descriptive study in Wau and Jur River, South Sudan by Peter Michael Marin, Morten Tryland, Musso Munyeme, Ambrose Samuel Jubara, Enock Matovu, Peter Waiswa, Javier Sanchez Romano, Francis Mutebi, David Onafruo, Estella Kitale, Esther Sabbath, Kayla J. Buhler, Clovice Kankya

Subjects: “…Mycobacterium tuberculosis…”
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Evaluation of a Commercial Multiplex Real-Time PCR with Melting Curve Analysis for the Detection of <i>Mycobacterium tuberculosis</i> Complex and Five Nontuberculous Mycobacterial Species by Keun Ju Kim, Yunhee Chang, Seung Gyu Yun, Myung-Hyun Nam, Yunjung Cho

“…Background: Accurate and timely diagnosis of mycobacterial infections, including <i>Mycobacterium tuberculosis</i> complex (MTBC) and nontuberculous mycobacteria (NTM), is crucial for effective disease management. …”
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Fitness costs of Mycobacterium tuberculosis resistant to rifampicin is compensated by rapid Th2 polarization mediated by early and high IL-4 production during mice infection by Ma. Fernanda Arce-Aceves, Roberto Espinosa-Neira, Dulce A. Mata-Espinosa, Jorge A. Barrios-Payan, Hugo G. Castelán-Sánchez, Sofía L. Alcaraz-Estrada, Mauricio Castañón-Arreola, Rogelio Hernández-Pando

“…Abstract It was a general belief that drug resistance in Mycobacterium tuberculosis (Mtb) was associated with lesser virulence, particularly rifampicin resistance, which is usually produced by mutations in the RNA polymerase Beta subunit (RpoB). …”
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Peptidoglycan-Like Components in Z-100, Extracted from Mycobacterium tuberculosis Strain Aoyama B, Increase IL-12p40 via NOD2 by Takayuki Horii, Yuki Orikawa, Yuta Ohira, Runa Eta, Uiko Tominaga, Takanori Sato, Takao Tanaka

“…Z-100 is a hot-water extract of the human-type Mycobacterium tuberculosis strain Aoyama B. While Z-100’s macrophage-mediated immunomodulatory effects have been reported, the mechanistic details have not been fully clarified. …”
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Culture-independent detection of Mycobacterium tuberculosis complex DNA using targeted next generation sequencing in African buffalo (Syncerus caffer) oronasal swabs in South Africa by Sinegugu Kholeka Mhlophe, Charlene Clarke, Giovanni Ghielmetti, Giovanni Ghielmetti, Megan Matthews, Tanya Jane Kerr, Michele Ann Miller, Wynand Johan Goosen, Wynand Johan Goosen

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Clinical Evaluation of a Rapid Reciprocal-Flow PCR Assay and Real-Time PCR Assay with Quenching Probe for Detection of <i>Mycobacterium tuberculosis</i> Complex by Kosuke Kosai, Keisuke Matsumoto, Takahisa Ishikawa, Yasuhide Kawamoto, Norihiko Akamatsu, Kenji Ota, Fujiko Mitsumoto-Kaseida, Norihito Kaku, Hiroo Hasegawa, Koichi Izumikawa, Hiroshi Mukae, Katsunori Yanagihara

“…This study investigated the diagnostic efficiencies of two assays for the detection of <i>Mycobacterium tuberculosis</i> complex: (1) the reciprocal-flow real-time polymerase chain reaction (PCR)-based GeneSoC assay and (2) the real-time PCR based GENECUBE MTB assay with quenching probe. …”
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Mycobacterium tuberculosis Multidrug-Resistant Strain M Induces Low IL-8 and Inhibits TNF-α Secretion by Bronchial Epithelial Cells Altering Neutrophil Effector Functions by Denise Kviatcovsky, Leonardo Rivadeneyra, Luciana Balboa, Noemí Yokobori, Beatriz López, Viviana Ritacco, Mirta Schattner, María del Carmen Sasiain, Silvia de la Barrera

“…M strain, the most prevalent multidrug-resistant strain of Mycobacterium tuberculosis (Mtb) in Argentina, has mounted mechanisms to evade innate immune response. …”
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Mycobacterium tuberculosis Lineage Distribution Using Whole-Genome Sequencing and Bedaquiline, Clofazimine, and Linezolid Phenotypic Profiles among Rifampicin-Resistant Isolates from West Java, Indonesia by Andriansjah Rukmana, Cynthia Gozali, Linda Erlina

“…Tuberculosis (TB) is caused by Mycobacterium tuberculosis infection. Indonesia is ranked second in the world for TB cases. …”
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Analytical and clinical validation of a novel MeltPlus TB-NTM/RIF platform for simultaneous detection of Mycobacterium tuberculosis complex, Non-Tuberculous Mycobacteria and rifampicin resistance by Zhuo Wang, Yuanwu Zou, Zihan Wei, Guanghong Bai, Xiaolin Wang, Shaoyi Qu, Jie Shi, Yaping Jiang, Cuijiao Gu

“…BackgroundRapid and accurate diagnosis of tuberculosis, particularly rifampin (RIF)-resistant tuberculosis (RR-TB) and Non-Tuberculous Mycobacteria (NTM), is essential for implementing appropriate proper therapy to benefit patients and improve TB/NTM patient management.MethodsIn this study, we developed a novel MeltPlus MTB-NTM/RIF platform, designed to simultaneously detect Mycobacterium tuberculosis complex (MTBC), NTM and RIF resistance. …”
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Using In Silico Methods to Identify Protein Tyrosine Kinase A (PtkA) Homolog in Non-Tuberculous Mycobacteria (NTM) by Swati Jaiswal, Sanjay Kumar

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Tuberculosis en la población privada de libertad by Pablo Cristiano de Souza, Rodrigo de Macedo Couto, Alec Brian Lacerda, Pãmela Rodrigues de Souza Silva, Omar Ariel Espinosa, Jaqueline Costa Lima

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Tuberculous Osteomyelitis of the Scapular Spine Revealing HIV-1 Infection by Khaoula Idsaid, Malika Idalene, Khadija Danaoui, Wiam Ait Driss, Rania Elfargani, Nabila Soraa, Noura Tassi

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Tuberculose na população privada de liberdade by Pablo Cristiano de Souza, Rodrigo de Macedo Couto, Alec Brian Lacerda, Pãmela Rodrigues de Souza Silva, Omar Ariel Espinosa, Jaqueline Costa Lima

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Cloning, expression, and purification of fusion antigens MPT83 and ESAT6 from the local strain of Mycobacterium tuberculosis in Escherichia coli as a seed vaccine candidate against tuberculosis by Rusdina Bte Ladju, Ahyar Ahmad, Abdul Karim, Rugaiyah Arfah, Rosana Agus, Najdah Hidayah, Muhammad Nasrum Massi, Astutiati Nurhasanah, Harningsih Karim, Irda Handayani

“…Eradicating tuberculosis (TB) globally is increasingly challenging with the growing number of drug-resistant Mycobacterium tuberculosis (M. tuberculosis) strains. The development of more potent TB vaccines is critical to complement overall TB control strategies and overcome the growing challenge of drug resistance. …”
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