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Reinforcing cancer immunotherapy with engineered porous hollow mycobacterium tuberculosis loaded with tumor neoantigens
Published 2025-02-01“…One approach is to stimulate antigen-presenting cells (APCs) to uptake neoantigens. Mycobacterium tuberculosis (MTb) contains pathogen-associated molecular patterns (PAMPs) recognized by APCs and adhesion molecules that facilitate MTb invasion of APCs. …”
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Data Mining Mycobacterium tuberculosis Pathogenic Gene Transcription Factors and Their Regulatory Network Nodes
Published 2018-01-01“…Tuberculosis (TB) is one of the deadliest infectious diseases worldwide. In Mycobacterium tuberculosis, changes in gene expression are highly variable and involve many genes, so traditional single-gene screening of M. tuberculosis targets has been unable to meet the needs of clinical diagnosis. …”
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Binding of CXCL8/IL-8 to Mycobacterium tuberculosis Modulates the Innate Immune Response
Published 2015-01-01“…IL-8 may aid with mounting an adequate response during infection with Mycobacterium tuberculosis (M. tb); however, the underlying mechanism remains largely unknown. …”
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Exploring the Genetic Landscape of Mycobacterium tuberculosis: Unlocking the Differences in Between Latent and Active Tuberculosis
Published 2024-12-01“…Background: Tuberculosis (TB), caused by Mycobacterium tuberculosis (MTB), can enter a dormant phase within host tissues, complicating treatment and highlighting the need to investigate the genetic changes associated with dormancy. …”
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Global epidemiology of Mycobacterium tuberculosis lineage 4 insights from Ecuadorian genomic data
Published 2025-01-01“…Abstract Tuberculosis is a global public health concern, and understanding Mycobacterium tuberculosis transmission routes and genetic diversity of M. tuberculosis is crucial for outbreak control. …”
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The epidemiology and gene mutation characteristics of pyrazinamide-resistant Mycobacterium tuberculosis clinical isolates in Southern China
Published 2025-12-01“…This study investigates the epidemic trend of pyrazinamide (PZA)-resistant tuberculosis in Southern China over 11 years (2012–2022) and evaluates the mutation characteristics of PZA resistance-related genes (pncA, rpsA, and panD) in clinical Mycobacterium tuberculosis (M. tuberculosis) isolates. To fulfil these goals, we analyzed the phenotypic PZA resistance characteristics of 14,927 clinical isolates for which Bactec MGIT 960 PZA drug susceptibility testing (DST) results were available, revealing that 2,054 (13.76%) isolates were resistant to PZA. …”
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Association between the rifampicin resistance mutations and rifabutin susceptibility in Mycobacterium tuberculosis: A meta-analysis
Published 2025-01-01Subjects: “…Mycobacterium tuberculosis…”
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An exacerbated phosphate starvation response triggers Mycobacterium tuberculosis glycerol utilization at acidic pH
Published 2025-01-01Subjects: “…Mycobacterium tuberculosis…”
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Development and evaluation of a single-tube nested PCR with colorimetric assay for Mycobacterium tuberculosis detection
Published 2024-06-01“…Molecular techniques have revolutionized tuberculosis (TB) diagnosis by offering a faster and more sensitive approach, detecting Mycobacterium tuberculosis (Mtb) DNA directly from samples. …”
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Diverse Molecular Genotypes of Mycobacterium tuberculosis Complex Isolates Circulating in the Free State, South Africa
Published 2016-01-01“…The aim of the study was to describe the diversity of Mycobacterium tuberculosis (M. tuberculosis) strain families in the Free State province of South Africa. …”
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Benzylated Sulfamethoxazole Derivatives with Improved Safety Profile as Potential Anti-Mycobacterium tuberculosis and Antibacterial Agents
Published 2023-01-01“…The sulfamethoxazole derivatives were successfully biologically evaluated against Mycobacterium tuberculosis, Staphylococcus aureus, and Chinese Hamster Ovarian (CHO) cells. …”
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Antimycobacterial Activity, Synergism, and Mechanism of Action Evaluation of Novel Polycyclic Amines against Mycobacterium tuberculosis
Published 2021-01-01“…Mycobacterium tuberculosis has developed extensive resistance to numerous antimycobacterial agents used in the treatment of tuberculosis. …”
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Systematic review of innate immune responses against Mycobacterium tuberculosis complex infection in animal models
Published 2025-01-01“…BackgroundMycobacterium tuberculosis (Mtb) complex (MTBC) includes ten species that affect mammals and pose a significant global health concern. …”
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Kesesuaian Uji Cepat Antigen Mycobacterium tuberculosis dengan Pulasan BTA pada Tersangka Tuberkulosis Paru
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Detection of Mycobacterium tuberculosis DNA in intraocular fluid of 11 suspected tuberculous uveitis patients by multiplex PCR
Published 2025-01-01Subjects: Get full text
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Protease shaving of Mycobacterium tuberculosis facilitates vaccine antigen discovery and delivery of novel cargoes to the Mtb surface
Published 2025-02-01“…In this study, we established a multiplexed and quantitative biochemical strategy to study the surface of Mycobacterium tuberculosis (Mtb) and identified new vaccine targets. …”
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Identification of CTL Epitopes on Efflux Pumps of the ATP-Binding Cassette and the Major Facilitator Superfamily of Mycobacterium tuberculosis
Published 2021-01-01“…With the increasing number of drug-resistant Mycobacterium tuberculosis (MTB) strains and prevalence of coinfection of MTB with human immunodeficiency virus, many challenges remain in the prevention and treatment of tuberculosis. …”
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Caracterización genotípica con oligonucleótidos espaciadores de aislados multidrogorresistentes de Mycobacterium tuberculosis en Cuba
Published 2022-08-01Subjects: “…complejo Mycobacterium tuberculosis…”
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