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Targeting protein synthesis pathways in MYC-amplified medulloblastoma
Published 2025-01-01Subjects: Get full text
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Interactions between Myc and Mediators of Inflammation in Chronic Liver Diseases
Published 2015-01-01“…These mediators are the driving force of many inflammatory liver disorders, which often result in fibrosis, cirrhosis, and liver tumorigenesis. c-Myc is involved in many cellular events such as cell growth, proliferation, and differentiation. c-Myc upregulates IL-8, IL-10, TNF-α, and TGF-β, while IL-1, IL-2, IL-4, TNF-α, and TGF-β promote c-Myc expression. …”
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Temporal Requirements of cMyc Protein for Reprogramming Mouse Fibroblasts
Published 2012-01-01“…Thus, the feasibility of substituting cMyc transgene with (non-integrative) recombinant “pTAT-mcMyc” protein delivery was assessed, without compromising reprogramming efficiency or the pluripotent phenotype. …”
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Processivity of C-Myc-Induced Telomerase Activation in Rat Cell Lines
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EI24 Suppresses Tumorigenesis in Pancreatic Cancer via Regulating c-Myc
Published 2018-01-01“…EI24 overexpression also resulted in reduced c-Myc expression, an oncogene in PDAC, accompanied with increased LC3B-II formation, increased Beclin-1, and diminished p62. …”
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VEGFA, MYC, and JUN are abnormally elevated in the synovial tissue of patients with advanced osteoarthritis
Published 2025-01-01Subjects: Get full text
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PRMT6 promotes colorectal cancer progress via activating MYC signaling
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Transcriptomic data reveals MYC as an upstream regulator in laying hen follicular recruitment
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Effects of Polymorphisms in Myc-Related Genes on Bleeding Complications in Patients with Stable Warfarin Responses
Published 2019-01-01“…This study aimed to identify the possible effects of Myc and 8q24 polymorphisms on bleeding complications in patients who maintained international normalized ratio (INR) of 2.0-3.0 with warfarin therapy after cardiac valve replacement. …”
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The Role of Indoxyl Sulfate in Exacerbating Colorectal Cancer During Chronic Kidney Disease Progression: Insights into the Akt/β-Catenin/c-Myc and AhR/c-Myc Pathways in HCT-116 Colorectal Cancer Cells
Published 2025-01-01“…The AhR antagonist CH223191 also inhibited c-Myc upregulation, indicating involvement of the AhR/c-Myc pathway. …”
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Clinicopathological importance of immunohistochemical expression of OCT4, c-MYC and Ki-67 in colorectal cancer
Published 2024-12-01Subjects: Get full text
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Double-Hit Primary Plasma Cell Leukemia with IGH/MYC and IGH/CCND1 Translocations
Published 2020-01-01“…IGH/CCND1 and IGH/MYC translocations may have contributed to abrupt onset of pPCL in this case.…”
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Investigating the Expression of c-Myc and BIRC5 in TRAIL and PBOX-15 treated Metastatic Prostate Cancer Cells
Published 2024-12-01Subjects: Get full text
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Human Bone Marrow Mesenchymal Stem Cells Promote Gastric Cancer Growth via Regulating c-Myc
Published 2018-01-01“…Moreover, we found that the c-Myc inhibitor JQ1 and c-Myc siRNA decreased the expression of c-Myc in hBM-MSC-CM-treated tumor cells in vitro. …”
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Bufalin targets the SRC-3/c-Myc pathway in chemoresistant cells to regulate metastasis induced by chemoresistance in colorectal cancer
Published 2025-02-01Subjects: Get full text
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Identifikasi Ekspresi Gen Myc pada Subkultur MCF-7 Breast Cancer Cell Line dengan Sel Punca
Published 2018-12-01“…Tujuan penelitian ini adalah mengidentifikasi ekspresi gen Myc pada cell line MCF-7 sebelum dan sesudah pemberian sel punca. …”
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In-depth inference of transcriptional regulatory networks reveals NPM1 as a therapeutic ribosomal regulator in MYC-amplified medulloblastoma
Published 2025-01-01“…Inhibition of NPM1 led to apoptosis, reduced c-Myc stability, and impaired translation in MYC-amplified Group 3 MB cells. …”
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