Assessment of Global and Local Alterations in Retinal Layer Thickness in Ins2 (Akita) Diabetic Mice by Spectral Domain Optical Coherence Tomography by Andrew W. Francis, Justin Wanek, Mahnaz Shahidi

“…The Ins2 (Akita) mouse is a spontaneous diabetic mouse model with a heterozygous mutation in the insulin 2 gene that results in sustained hyperglycemia. …”
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Trends and Progress on Antibiotic-Resistant Mycobacterium tuberculosis and Genes in relation to Human Immunodeficiency Virus by N. G. Mbewana Ntshanka, T. A. M. Msagati

“…Over and above, the impetuous evolution, mutation, and the transfer of resistant genes via horizontal gene transfer are well-known contributive factors towards the antimicrobial resistance problem. …”
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Reconstructing Village Druwe Land Administration to Protect the Communal Land in Bali by Sukirno Sukirno, Muh Afif Mahfud, Muhammad Fahad Malik

“…Therefore, the ideal construction of customary land administration in Bali is a change in legal politics to strong legal pluralism including changes in the conversion provisions of the Basic Agrarian Law which convert customary land to property rights, participatory land administration even up to the stage of citizen control and also detailed land administration including land history, land mutation, land boundaries and land stewardship.…”
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Comprehensive case report and literature review on perioperative management of multiple pheochromocytoma in a pediatric patient by Shenghua Yu, Tianxiao Zou, Sisi Wei, Yani Yu, Guili Ding

“…Subsequent genetic testing identified a mutation in the VHL gene. After further medical management, the left adrenal tumor was also successfully removed. …”
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A Novel MOEA/D for Multiobjective Scheduling of Flexible Manufacturing Systems by Xinnian Wang, Keyi Xing, Chao-Bo Yan, Mengchu Zhou

“…A type of a discrete differential evolution (DDE) algorithm is also developed for solving each subproblem. The mutation operator of the proposed DDE is based on the hamming distance of two randomly selected solutions, while the crossover operator is based on Generalization of Order Crossover. …”
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An enhanced dung beetle optimizer with multiple strategies for robot path planning by Wei Hu, Qi Zhang, Shan Ye

“…Thirdly, T-distribution mutation and differential evolutionary variation strategies are introduced to provide perturbation to enhance the diversity of the population and avoid falling into local optimization. …”
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The Study on Large-Diameter Drilling Prevention Method of Rock Burst in the Xinxing Coal by Gao Xu, Zuo Minghui, Shu Yanmin

“…The distribution of stress and plastic zone in drilling surrounding rock and its influence parameters are clarified, and the distribution of the “butterfly plastic zone” and the mutation condition of the “butterfly plastic zone” in trigger stress state are explored. …”
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The genetic architecture of local adaptation in a cline by Laroche, Fabien, Lenormand, Thomas

“…In particular, it required that migration rate was neither too low nor too large and that the full optimization of trait values could not be eventually achieved by a mutation at a single locus. Here, we investigate this question in a spatially-explicit model, considering two contiguous habitats with distinct trait optima on a circular stepping-stone. …”
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Rupture and Migration Law of Disturbed Overburden during Slicing Mining of Steeply Dipping Thick Coal Seam by Shuai Liu, Ke Yang, Chunan Tang, Xiaolou Chi

“…The results show that the mutation of the hinged rock beam structure in the lower region and the cantilever beam structure in the upper region of the lower slice disturbed overburden is the main cause of the rupture of the workface roof. …”
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Iron oxide nanoparticles coated with bioactive materials: a viable theragnostic strategy to improve osteosarcoma treatment by Amy Sarah Benjamin, Sunita Nayak

“…Understanding the complexities of tumor development and mutation is the need of the hour for the advancement of targeted therapies in cancer care. …”
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A 16-Year-Old Male with Thoracic Compression following Posterior Spinal Instrumentation and Fusion for Marfan-Associated Syndromic Scoliosis by Mason Uvodich, Ross Barman, Adam Reitz, Matthew Sexton

“…Marfan syndrome is an autosomal dominant disorder caused by a mutation in the FBN1 gene which affects connective tissue. …”
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Asymptomatic Familial Multiple Cerebral Cavernous Malformation in a 73-Year-Old Woman by Klenam Dzefi-Tettey, Emmanuel Kobina Mesi Edzie, Philip Narteh Gorleku, Henry Kusodzi, Abdul Raman Asemah

“…The familial form is an autosomal dominant gene mutation disorder. This condition can be diagnosed with magnetic resonance imaging (MRI) and computed tomography (CT) scan, but the modality of choice is MRI because of its high sensitivity. …”
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Identifying key genes in cancer networks using persistent homology by Rodrigo Henrique Ramos, Yago Augusto Bardelotte, Cynthia de Oliveira Lage Ferreira, Adenilso Simao

“…This study presents a novel method using Persistent Homology to analyze the role of driver genes in higher-order structures within Cancer Consensus Networks derived from main cellular pathways. We integrate mutation data from six cancer types and three biological functions: DNA Repair, Chromatin Organization, and Programmed Cell Death. …”
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Adding checkpoint inhibitors to first-line chemotherapy for NUT carcinoma patients by Sarah Haebe, Gesa Schuebbe, Philipp Jurmeister, Michael von Bergwelt-Baildon, C. Benedikt Westphalen, Ulrich M. Lauer, Wolfgang G. Kunz, Marion Subklewe, Oliver Weigert

“…We conducted a comprehensive analysis of this patient’s tumor, including Tumor Mutation Burden, Microsatellite Instability, and genetic profiling to explore further putative druggable targets. …”
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Characterization of the Protective HIV-1 CTL Epitopes and the Corresponding HLA Class I Alleles: A Step towards Designing CTL Based HIV-1 Vaccine by Sajib Chakraborty, Taibur Rahman, Rajib Chakravorty

“…Human immunodeficiency virus (HIV) possesses a major threat to the human life largely due to the unavailability of an efficacious vaccine and poor access to the antiretroviral drugs against this deadly virus. High mutation rate in the viral genome underlying the antigenic variability of the viral proteome is the major hindrance as far as the antibody based vaccine development is concerned. …”
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HapNetworkView: a tool for haplotype network exploration and visualization by Lianjiang Chi, Yi Dong, Ruizhen Wang, Suiyuan Yang, Lan Wu, Yongbiao Xue, Hua Chen

“…Results We present HapNetworkView, a user-friendly tool that facilitates the construction and interactive visualization of haplotype networks, enabling users to explore haplotypes and mutation information effectively. HapNetworkView offers both automatic optimization and manual adjustment for haplotype network layouts. …”
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Extensive Thrombosis of the Inferior Vena Cava and Left Renal Vein in a Neonate by Moez Kdous, Oussema Khlifi, Marwene Brahem, Mohamed Khrouf, Sarah Amari, Monia Ferchiou, Fethi Zhioua

“…A review of thrombophilia was carried out and a heterozygous mutation in Factor V was found in both the mother and the child.…”
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Differential Signature of the Centrosomal MARK4 Isoforms in Glioma by Ivana Magnani, Chiara Novielli, Laura Fontana, Silvia Tabano, Davide Rovina, Ramona F. Moroni, Dario Bauer, Stefania Mazzoleni, Elisa A. Colombo, Gabriella Tedeschi, Laura Monti, Giovanni Porta, Silvano Bosari, Carolina Frassoni, Rossella Galli, Lorenzo Bello, Lidia Larizza

“…Methods: We performed mutation analysis to identify sequence alterations possibly affecting MARK4 expression. …”
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De Novo or inherited: gonosomal mosaicism in hereditary angioedema due to C1 inhibitor deficiency by Laura Batlle-Masó, Laura Batlle-Masó, Laura Batlle-Masó, Janire Perurena-Prieto, Janire Perurena-Prieto, Janire Perurena-Prieto, Laura Viñas-Giménez, Laura Viñas-Giménez, Laura Viñas-Giménez, Aina Aguiló-Cucurull, Aina Aguiló-Cucurull, Paula Fernández-Álvarez, Johana Gil-Serrano, Johana Gil-Serrano, Johana Gil-Serrano, Mar Guilarte, Mar Guilarte, Mar Guilarte, Roger Colobran, Roger Colobran, Roger Colobran, Roger Colobran

“…In the patient, we identified a novel splice site mutation in SERPING1 (c.890-1G>C) and, by cDNA analysis, we confirmed its pathogenicity. …”
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One-step diagnosis of infection and lung cancer using metagenomic sequencing by Shaoqiang Li, Yangqing Zhan, Yan Wang, Weilong Li, Xidong Wang, Haoru Wang, Wenjun Sun, Xuefang Cao, Zhengtu Li, Feng Ye

“…Notably, more abundant CNV mutation types and higher mutation rates were observed in adenocarcinoma (ADC) compared to squamous cell carcinoma (SCC). …”
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