Identification of maize kernel varieties based on interpretable ensemble algorithms by Chunguang Bi, Chunguang Bi, Xinhua Bi, Jinjing Liu, Hao Xie, Shuo Zhang, He Chen, Mohan Wang, Lei Shi, Lei Shi, Shaozhong Song

“…The base learner of the Stacking integration model was selected using diversity and performance indices, with parameters optimized through a differential evolution algorithm incorporating multiple mutation strategies and dynamic adjustment of mutation factors and recombination rates. …”
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Hereditary transthyretin amyloidosis incidentally diagnosed by video-associated lung surgery for lung cancer: A case report by Katsuhiro Itogawa, Shintaro Sato, Hideaki Yamakawa, Keiichi Akasaka, Masako Amano, Akiko Adachi, Hidekazu Matsushima

“…In addition, further pathological investigation of the background lung tissue revealed deposition of amyloid transthyretin (TTR), although no radiological findings suggestive of pulmonary amyloidosis were present. A genetic mutation screening test revealed pathological TTR gene mutation of heterozygous Tyr114His (p.Tyr134His). …”
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Serum connexin 26 as a potential marker of non-syndromic hearing loss by Hend M. Moness, Noha M. Abdullah, Doaa El Amrousy, Reham Gamal, Hatem A. Mohamed, Mohammed A. Gomaa, Shaimaa Moustafa Hafez, Zamzam Hassan Mohamed

“…Measuring of connexin 26 by ELISA is more sensitive and specific than 35 del G mutation where sensitivity was 11.45 and 5.7% for both hetero and homo mutation. …”
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A graph neural network approach for hierarchical mapping of breast cancer protein communities by Xiao Zhang, Qian Liu

“…The resulting hierarchical map of protein communities shows how gene-level mutations and survival information converge on protein communities at different scales. …”
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Assessment of MGMT and TERT Subtypes and Prognosis of Glioblastoma by Whole Tumor Apparent Diffusion Coefficient Histogram Analysis by Ling Chen, Min Wu, Yao Li, Lifang Tang, Chuyun Tang, Lizhao Huang, Tao Li, Li Zhu

“…Results: MGMT promoter methylation and TERT promoter mutation were detected in 53.2% and 44.3% of GBM patients, respectively. …”
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Enhancement of Streptomyces aureoverticillatus HN6 through mutagenesis for improved biocontrol of banana wilt disease: an WGS approach by Xiangnan Yan, Shakil Ahmad, Nazia Manzar, Yunfei Zhang, Coline C. Jaworski, Abhijeet Shankar Kashyap, Lanying Wang, Yanping Luo

“…These findings serve as a valuable technical reference for the mutation breeding of Streptomyces. Graphical Abstract…”
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Integrating multiomics analysis and machine learning to refine the molecular subtyping and prognostic analysis of stomach adenocarcinoma by Miaodong Wang, Qin He, Zeshan Chen, Yijue Qin

“…We downloaded the multiomics data of STAD patients in The Cancer Genome Atlas (TCGA)-STAD cohort, which included mRNA, microRNA, long non-coding RNA, somatic mutation, and DNA methylation data, from the sxdyc website. …”
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3′ Splice Site Sequences of Spinal Muscular Atrophy Related SMN2 Pre-mRNA Include Enhancers for Nearby Exons by Sunghee Cho, Heegyum Moon, Tiing Jen Loh, Hyun Kyung Oh, Hey-Ran Kim, Myung-Geun Shin, D. Joshua Liao, Jianhua Zhou, Xuexiu Zheng, Haihong Shen

“…Spinal muscular atrophy (SMA) is a human genetic disease which occurs because of the deletion or mutation of SMN1 gene. SMN1 gene encodes the SMN protein which plays a key role in spliceosome assembly. …”
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EXO1 is a key gene for lung-resident memory T cells and has diagnostic and predictive values for lung adenocarcinoma by Zhuoqi Li, Xiaoyan Lin, Yuanhui Yang, Mei Tian, Lu Zhang, Fujing Huang, Xiao Wen, Zhigang Wei, Yuan Tian

“…Moreover, patients with EXO1 mutation had worse DSS, DFI and PFI.…”
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Genetic markers on the distribution of ancient marine hunters in Priokhotye by B. A. Malyarchuk

“…The data on mitochondrial DNA polymorphism and the “Arctic” mutation distribution – the rs80356779-A variant of the CPT1A gene – were analyzed. …”
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Frameshift variation in the HMG-CoA reductase gene and unresponsiveness to cholesterol-lowering drugs in type 2 diabetes mellitus patients by Esmat Khaleqsefat, Khder Hussein Rasul, Ramiar Kamal Kheder, Sonia Baban, Jamil Baban

“…These two patients showed non-responsiveness to atorvastatin 40 mg due to a genetic mutation in the HMGCR gene. This mutation altered the amino acid sequence in the flap domain, replacing isoleucine with a stop codon. …”
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Ensemble machine learning models for lung cancer incidence risk prediction in the elderly: a retrospective longitudinal study by Songjing Chen, Sizhu Wu

“…Men ≥ 65 carrying C > A/G > T mutation had the highest lung cancer incidence decrease of 39.5% after five years quitting in stratified elderly groups, which were 1.83 times more than women ≥ 65 not carrying C > A/G > T mutation. …”
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Topology Optimization of the Network with Renewable Energy Sources Generation Based on a Modified Adapted Genetic Algorithm by A. M. Bramm, A. I. Khalyasmaa, S. A. Eroshenko, P. V. Matrenin, N. A. Papkova, D. A. Sekatski

“…The proposed genetic algorithm used two different functions of interbreeding, the function of mutation, selection of the best individuals and mass mutation (complete population renewal). …”
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Ongoing measles outbreak in Romania: Clinical investigation and molecular epidemiology performed on whole genome sequences. by Robert Hohan, Marius Surleac, Victor Daniel Miron, Andreea Tudor, Ana-Maria Tudor, Oana Săndulescu, Ovidiu Vlaicu, Victoria Aramă, Daniela Pițigoi, Adriana Hristea, Anca Cristina Drăgănescu, Dimitrios Paraskevis, Leontina Bănică, Dan Oțelea, Simona Paraschiv

“…Furthermore, these two clusters presented different mutation profiles in the hemagglutinin (HA) and neuraminidase (N) genes with implications for molecular surveillance.…”
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Monoallelic variants resulting in substitutions of MAB21L1 Arg51 Cause Aniridia and microphthalmia. by Hildegard Nikki Hall, Hemant Bengani, Robert B Hufnagel, Giuseppe Damante, Morad Ansari, Joseph A Marsh, Graeme R Grimes, Alex von Kriegsheim, David Moore, Lisa McKie, Jamalia Rahmat, Catia Mio, Moira Blyth, Wee Teik Keng, Lily Islam, Meriel McEntargart, Marcel M Mannens, Veronica Van Heyningen, Joe Rainger, Brian P Brooks, David R FitzPatrick

“…These mutations occurred de novo in 3/5 families, with the remaining families being compatible with autosomal dominant inheritance. …”
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Impact of Tunnel Groups on Pupil Diameter of Drivers on Mountainous Freeway in China: A Real-World Driving Study by Jianping Gao, Sijie Zhang, Yunyong He, Qi Zhang, Lu Sun, Chang Lu, Yi Wu, Enhuai He, Changfeng Yang

“…Subsequently, a related model for the PPDV of drivers and the length of the connecting zone between tunnels was established, its reliability evaluated, and the smooth mutation value obtained on the basis of the mutation theory. …”
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Assessment of Self-Activation and Inhibition of Wheat Coiled-Coil Domain Containing NLR Immune Receptor Yr10_CG by Nan Wu, Wanqing Jiang, Zhaoxia Xiang, Raheel Asghar, Mahinur S. Akkaya

“…However, we observed that mutations in the conserved MHD motif, specifically D502G, activated Yr10_CG and induced cell death. …”
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Deep Vein Thrombosis and Pulmonary Embolism Secondary to Thrombophilic Disorder: A Case Report by Satbir Kaur Malik, Vineetha Naga Lakshmi Giduturi, Sindhuri Goud Nimmala, Vijayashree Gokhale

“…The most common inherited thrombophilias—such as Factor V Leiden mutation, prothrombin G20210A mutation and deficiencies in protein C, protein S and antithrombin III—are a group of genetic conditions that predispose individuals to thrombotic events by influencing various factors involved in the coagulation cascade. …”
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Beyond the Definitions of the Phenotypic Complications of Sickle Cell Disease: An Update on Management by Samir K. Ballas, Muge R. Kesen, Morton F. Goldberg, Gerard A. Lutty, Carlton Dampier, Ifeyinwa Osunkwo, Winfred C. Wang, Carolyn Hoppe, Ward Hagar, Deepika S. Darbari, Punam Malik

“…The sickle hemoglobin is an abnormal hemoglobin due to point mutation (GAG → GTG) in exon 1 of the β globin gene resulting in the substitution of glutamic acid by valine at position 6 of the β globin polypeptide chain. …”
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Reducing neonatal Fc receptor binding enhances clearance and brain-to-blood ratio of TfR-delivered bispecific amyloid-β antibody by Eva Schlein, Ken G. Andersson, Tiffany Dallas, Stina Syvänen, Dag Sehlin

“…A variant of each antibody was designed to harbor a mutation to the neonatal Fc receptor (FcRn) binding domain, to increase clearance. …”
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