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201
Causal Relationship Between Emotional Disorders and Thyroid Disorders: A Bidirectional Two‐Sample Mendelian Randomization Study
Published 2025-01-01“…Methods We employed several methods, including inverse‐variance weighted (IVW), weighted median, weighted mode, and MR Egger regression. Additionally, sensitivity analyses were conducted using MR‐Egger, MR Pleiotropy Residual Sum and Outlier (MR‐PRESSO), Cochran's Q, and leave‐one‐out methods. …”
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202
Physical activities and breast cancer: a Mendelian randomization study
Published 2024-11-01“…The inverse variance weighted method was employed as the primary approach for two-sample MR. Additionally, the MR-PRESSO (MR-Pleiotropy RESidual Sum and Outlier) method was utilized to eliminate outliers. …”
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203
A Bidirectional Mendelian Randomization Study Investigating the Causal Relationship Between Ankylosing Spondylitis and Chronic Obstructive Pulmonary Disease
Published 2025-02-01“…The analysis utilized publicly available statistics on AS and COPD from the Genome-wide Association Study (GWAS). The primary MR method employed was Inverse-Variance Weighting (IVW), supplemented by additional MR methods such as weighted median, MR-Egger, simple mode, and weighted mode. …”
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204
Potential and costs required for methane removal to compete with BECCS as a mitigation option
Published 2025-01-01“…MR is technologically very challenging and potentially very expensive, so the main question is at which cost per ton of methane removed is MR more cost effective than CDR. …”
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205
Systematic comparison of Mendelian randomisation studies and randomised controlled trials using electronic databases
Published 2023-09-01“…Among intervention types that can be mimicked by MR, only trials of pharmaceutical interventions could be automatically matched to MR results due to insufficient annotation with Medical Subject Headings ontology. …”
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206
Surgical Outcome of Medial Rectus Resection in Recurrent Exotropia: A Novel Surgical Formula
Published 2015-01-01“…All surgeries were performed according to the formula: 1.0 mm MR muscle resection for every 5 prism dioptres (PD) of exotropia, with an addition of 0.5 mm to each MR muscle operated on. …”
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207
Biological Reduction of Perchlorate from Spent Modified Reed Mediated by an Enriched Microbial Culture
Published 2023-01-01“…Disposal of untreated perchlorate-laden modified reed (MR) generated in the treatment of contaminated water risks further contamination issues. …”
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208
Choice white grease used for manufacturing a protein-encapsulated fat blend source for neonatal calves
Published 2025-02-01“…ABSTRACT: Protein-encapsulated fat (PEF) blends are routinely used for manufacturing calf milk replacers (MR). The use of PEF blends improves fat mixability to ensure MR when mixed and fed as a homogeneous solution for neonatal calves. …”
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209
Causal association between non-thyroidal autoimmune diseases and Graves' ophthalmopathy: A mendelian randomization study
Published 2025-02-01“…Cochran's Q statistic was used to assess the heterogeneity between SNP estimates. MR-Egger regression was used to evaluate horizontal pleiotropy and MR pleiotropy residual sum and outlier (MR-PRESSO) test was used to detect the outliers. …”
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210
Association between chronic obstructive pulmonary disease and osteoporosis: Mendelian randomization combined with bibliometric analysis
Published 2025-02-01“…The results of the primary IVW MR Analysis were generally supported by our sensitivity MR Analysis. …”
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211
Newton Method to Recover the Phase Accumulated during MRI Data Acquisition
Published 2012-01-01“…For an internal conductivity image, magnetic resonance electrical impedance tomography (MREIT) injects an electric current into an object and measures the induced magnetic flux density, which appears in the phase part of the acquired MR image data. To maximize signal intensity, the injected current nonlinear encoding (ICNE) method extends the duration of the current injection until the end of the MR data reading. …”
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212
Phenotyping determination of cyp1a2 enzyme activity using caffeine in sheep
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213
Is Vitamin D Deficiency the Cause or the Effect of Systemic Lupus Erythematosus: Evidence from Bidirectional Mendelian Randomization Analysis
Published 2022-01-01“…Sensitivity analyses including maximum likelihood, MR-Egger method, penalized weighted median method, MR-PRESSO, MR-RAPS, and MR-radial method were conducted. …”
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214
Mendelian randomization analysis reveals causal relationship between tonsillectomy and irritable bowel syndrome
Published 2025-01-01“…Instrumental variables (IVs) were SNPs strongly correlated and independent of tonsillectomy. MR-PRESSO was used for outlier removal. IVW was the primary MR analysis method, supplemented by MR-Egger regression, WM, WME, and simple mode. …”
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215
Causal linkage between adult height and kidney function: An integrated population-scale observational analysis and Mendelian randomization study.
Published 2021-01-01“…Second, the genetic instrument for adult height, as reported by the GIANT consortium, was implemented, and summary-level MR of eGFRcreatinine and CKDcreatinine in a CKDGen genome-wide association study was performed (N = 567,460), with multivariable MR being adjusted for the effects of genetic predisposition on body mass index. …”
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216
Causal Associations Between Sarcopenia and Gestational Diabetes Mellitus
Published 2025-02-01“…A bi-directional MR study was conducted. First, a forward MR analysis evaluated the causality of sarcopenia on GDM risk, with sarcopenia-related traits as exposures and GDM as the outcome. …”
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217
Associations among immunophenotype, plasma metabolites, and benign prostatic hyperplasia: a mediation Mendelian randomization study
Published 2025-01-01“…Objective To explore the potential causal relationship between immune cells, plasma metabolites and benign prostatic hyperplasia (BPH) and the mediating role of plasma metabolism by using the mediated Mendelian randomization (MR) method. Methods Two-sample bidirectional MR analysis was used to predict the immune phenotype that may affect BPH, and immune cells that were adversely affected by BPH were excluded. …”
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218
Bias-corrected serum creatinine from UK Biobank electronic medical records generates an important data resource for kidney function trajectories
Published 2025-01-01“…When comparing eMR-based with SC-based creatinine by calendar year (n = 70,231), we found a year-specific multiplicative bias for eMR-based creatinine that decreased over time (factor 0.84 for 2007, 0.97 for 2013). …”
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219
Diabetes and tuberculosis: a systematic review and meta-analyis of mendelian randomization evidence
Published 2025-02-01“…Studies were screened based on pre-specified inclusion criteria and assessed for quality using the STROBE-MR guidelines. Data extraction focused on study characteristics, MR methodology, and causal effect estimates. …”
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220
Transcatheter edge to edge compared with surgery in older patients with degenerative mitral valve regurgitation
Published 2025-01-01“…Abstract Objectives Transcatheter edge-to-edge repair (TEER) is an alternative for patients with severe degenerative mitral regurgitation (MR). The objective of this study was to compare the outcomes of surgery and TEER in older patients with degenerative MR patients using real life data. …”
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