Noninvasive in vivo imaging of macrophages: understanding tumor microenvironments and delivery of therapeutics by Prakash Gangadaran, Akanksha Onkar, Ramya Lakshmi Rajendran, Anshika Goenka, Ji Min Oh, Fatima Khan, ArulJothi Kandasamy Nagarajan, Sathish Muthu, Anand Krishnan, Chae Moon Hong, Byeong-Cheol Ahn

“…The review concludes by offering insights into the applicability of molecular imaging techniques for real time monitoring of macrophages in preclinical and clinical scenarios.…”
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Duodenal Organoids From Metabolic Dysfunction-Associated Steatohepatitis Patients Exhibit Absorptive and Barrier Alterations by Alia Hadefi, Morgane Leprovots, Gilles Dinsart, Maryam Marefati, Marjorie Vermeersch, Daniel Monteyne, David Pérez-Morga, Anne Lefort, Frédérick Libert, Laurine Verset, Claire Liefferinckx, Christophe Moreno, Jacques Devière, Eric Trépo, Marie-Isabelle Garcia

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Discordance between 90Y-PET/CT(MR)-estimated activity and dose calibrator measured administered activity: an international study in SIRT patients treated with resin and glass micro... by Thomas Carlier, Silvano Gnesin, Justin K. Mikell, Maurizio Conti, John O. Prior, Niklaus Schaefer, Maria del Sol Pérez Lago, Clément Bailly, Yuni K. Dewaraja, Thiago V. M. Lima

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Mathematical Study and Numerical Simulation of Multispectral Bioluminescence Tomography by Weimin Han, Wenxiang Cong, Ge Wang

“…Multispectral bioluminescence tomography (BLT) attracts increasingly more attention in the area of optical molecular imaging. In this paper, we analyze the properties of the solutions to the regularized and discretized multispectral BLT problems. …”
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Radiomic prediction for durable response to high‐dose methotrexate‐based chemotherapy in primary central nervous system lymphoma by Haoyi Li, Mingming Xiong, Ming Li, Caixia Sun, Dao Zheng, Leilei Yuan, Qian Chen, Song Lin, Zhenyu Liu, Xiaohui Ren

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Physical parameters and biological factors affect the abscopal effect of combining radiotherapy with immunotherapy: an update on preclinical works by Wangcai Ren, Jialing Wen, Gang Guo, Gang Guo, Wenchao Gu, Shenke Zhang, Shenke Zhang, Chang Liu, Chang Liu, Kensuke Osada, Takashi Shimokawa, Qiaojuan Wang, Qiaojuan Wang, Yue Wang, Yue Wang, Xuanzhang Tu, Chen Li, Li Sui, Liqiu Ma, Liqiu Ma, Liqiu Ma

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Diagnostic impact of DNA methylation classification in adult and pediatric CNS tumors by Laetitia Lebrun, Nathalie Gilis, Manon Dausort, Chloé Gillard, Stefan Rusu, Karim Slimani, Olivier De Witte, Fabienne Escande, Florence Lefranc, Nicky D’Haene, Claude Alain Maurage, Isabelle Salmon

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Improving timing resolution of BGO for TOF-PET: a comparative analysis with and without deep learning by Francis Loignon-Houle, Nicolaus Kratochwil, Maxime Toussaint, Carsten Lowis, Gerard Ariño-Estrada, Antonio J. Gonzalez, Etiennette Auffray, Roger Lecomte

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Metagenomic and Transcriptomic Analysis Reveals Crosstalk Between Intratumor Mycobiome and Hosts in Early‐Stage Nonsmoking Lung Adenocarcinoma Patients by Yaohui Sun, Zhiming Gan, Shijiancong Liu, Sheng Zhang, Wei Zhong, Jian Liu, Xiuting Huang, Wei He, Hongcheng Zhong, Qingdong Cao

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Repeated positron emission tomography tracing neutrophil elastase in a porcine intensive-care sepsis model by Frida Wilske, Olof Eriksson, Rose-Marie Amini, Sergio Estrada, Helena Janols, Amina Khalil, Anders Larsson, Miklós Lipcsey, Sara Mangsbo, Jonathan Sigfridsson, Jan Sjölin, Paul Skorup, Anders Wall, Viola Wilson, Markus Castegren, Gunnar Antoni

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Iron(III)–Quercetin Complex: In Vivo Acute Toxicity and Biodistribution of Novel MRI Agent by Innuan P, Kongkarnka S, Thongtharb A, Kantapan J, Dechsupa N

“…Phattarawadee Innuan,1,2 Sarawut Kongkarnka,3 Atigan Thongtharb,4 Jiraporn Kantapan,1,2 Nathupakorn Dechsupa1,2 1Molecular Imaging and Therapy Research Unit, Department of Radiologic Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, 50200, Thailand; 2Department of Radiologic Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, 50200, Thailand; 3Department of Pathology, Faculty of Medicine, Chiang Mai University, Chiang Mai, 50200, Thailand; 4Department of Companion Animal and Wildlife Clinic, Faculty of Veterinary Medicine, Chiang Mai University, Chiang Mai, 50100, ThailandCorrespondence: Nathupakorn Dechsupa; Jiraporn Kantapan, Molecular Imaging and Therapy Research Unit, Department of Radiologic Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, 50200, Thailand, Email nathupakorn.d@cmu.ac.th; Jiraporn.kan@cmu.ac.thBackground: The iron(III)–quercetin complex, known as “IronQ”, is an innovative MRI contrast agent composed of one Fe(III) ion and two quercetin molecules. …”
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First‐in‐human orbital tumor surgery guided by near‐infrared II window fluorescence imaging: A feasibility study by Zeyu Zhang, Lishuang Guo, Lan Yao, Yueyue Li, Yan Hei, Qi Wang, Xiaoyi Wang, Rui Ma, Xinji Yang, Zhenhua Hu, Wei Wu

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Oligodendrocyte precursor cells facilitate neuronal lysosome release by Li-Pao Fang, Ching-Hsin Lin, Yasser Medlej, Renping Zhao, Hsin-Fang Chang, Qilin Guo, Zhonghao Wu, Yixun Su, Na Zhao, Davide Gobbo, Amanda Wyatt, Vanessa Wahl, Frederic Fiore, Szu-Min Tu, Ulrich Boehm, Wenhui Huang, Shan Bian, Amit Agarwal, Marcel A. Lauterbach, Chenju Yi, Jianqin Niu, Anja Scheller, Frank Kirchhoff, Xianshu Bai

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Non‐Invasive Photoacoustic Cerebrovascular Monitoring of Early‐Stage Ischemic Strokes In Vivo by Jiwoong Kim, Joo Young Kweon, Seongwook Choi, Hyunseo Jeon, Minsik Sung, Rongkang Gao, Chengbo Liu, Chulhong Kim, Yong Joo Ahn

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Improving the Performance of Phase-Change Perfluorocarbon Droplets for Medical Ultrasonography: Current Progress, Challenges, and Prospects by Paul S. Sheeran, Paul A. Dayton

“…In this review, we survey our recent work to enhance the performance of phase-change agents for ultrasound through a variety of techniques in order to provide increased efficacy in therapeutic applications of ultrasound and enable previously unexplored applications in diagnostic and molecular imaging.…”
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First Clinical Experience of ⁶⁸Ga-FAPI PET/CT in Tertiary Cancer Center: Identifying Pearls and Pitfalls by Akram Al-Ibraheem, Ahmed Saad Abdlkadir, Ula Al-Rasheed, Dhuha Al-Adhami, Feras Istatieh, Farah Anwar, Marwah Abdulrahman, Rula Amarin, Issa Mohamad, Asem Mansour

“…This retrospective study aims to explore tracer uptake metrics across various epithelial neoplasms, identify diagnostic pitfalls associated with ⁶⁸Ga-FAPI PET/CT, and evaluate the influence of ⁶⁸Ga-FAPI PET/CT staging results on changes in therapeutic intent compared to gold standard molecular imaging modalities. <b>Methods:</b> A total of 48 patients with biopsy-confirmed solid tumors underwent 77 ⁶⁸Ga-FAPI PET/CT examinations for molecular imaging assessment, encompassing neoplasms originating from the gastrointestinal tract, head and neck, hepatobiliary system, pancreas, breast, and lung. …”
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EGFR-Mutant Lung Adenocarcinoma Mimicking a Pneumonia by Álvaro Taus, Flavio Zuccarino, Carlos Trampal, Edurne Arriola

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Autophagy-lysosome pathway in insulin & glucagon homeostasis by Yi Wu, Yi Wu, Yi Wu, Hui Wang, Huoyan Xu

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Modern Endoscopic Imaging in Diagnosis and Surveillance of Inflammatory Bowel Disease Patients by Gheorghe Hundorfean, Stephen P. Pereira, John G. Karstensen, Peter Vilmann, Adrian Saftoiu

“…Here, we review the relevant literature regarding commonly used endoscopic techniques (dye-based and digital chromoendoscopy, high-definition endoscopy, capsule endoscopy, and endosonography), as well as advanced and experimental technologies (full-spectrum endoscopy, endocytoscopy, autofluorescence, laser endoscopy, and endomicroscopy, including molecular imaging), applicable to inflammatory bowel diseases and emerging for implementation into everyday practice. …”
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