Showing 1 - 20 results of 20 for search '"Molecular Neurodegeneration"', query time: 0.05s Refine Results
  1. 1
    VCP regulates early tau seed amplification via specific cofactors

    VCP regulates early tau seed amplification via specific cofactors by Sushobhna Batra, Jaime Vaquer-Alicea, Clarissa Valdez, Skyler P. Taylor, Victor A. Manon, Anthony R. Vega, Omar M. Kashmer, Sourav Kolay, Andrew Lemoff, Nigel J. Cairns, Charles L. White, Marc I. Diamond

    Published 2025-01-01
    “…Molecular Neurodegeneration…”
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  2. 2
    Emerging targets of α-synuclein spreading in α-synucleinopathies: a review of mechanistic pathways and interventions

    Emerging targets of α-synuclein spreading in α-synucleinopathies: a review of mechanistic pathways and interventions by Grace Kuo, Ramhari Kumbhar, William Blair, Valina L. Dawson, Ted M. Dawson, Xiaobo Mao

    Published 2025-01-01
    “…Molecular Neurodegeneration…”
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  3. 3
    SIRT2 and ALDH1A1 as critical enzymes for astrocytic GABA production in Alzheimer’s disease

    SIRT2 and ALDH1A1 as critical enzymes for astrocytic GABA production in Alzheimer’s disease by Mridula Bhalla, Jinhyeong Joo, Daeun Kim, Jeong Im Shin, Yongmin Mason Park, Yeon Ha Ju, Uiyeol Park, Seonguk Yoo, Seung Jae Hyeon, Hyunbeom Lee, Junghee Lee, Hoon Ryu, C. Justin Lee

    Published 2025-01-01
    “…Molecular Neurodegeneration…”
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  4. 4
    Mis-localization of endogenous TDP-43 leads to ALS-like early-stage metabolic dysfunction and progressive motor deficits

    Mis-localization of endogenous TDP-43 leads to ALS-like early-stage metabolic dysfunction and progressive motor deficits by Yiying Hu, Alexander Hruscha, Chenchen Pan, Martina Schifferer, Michael K. Schmidt, Brigitte Nuscher, Martin Giera, Sarantos Kostidis, Özge Burhan, Frauke van Bebber, Dieter Edbauer, Thomas Arzberger, Christian Haass, Bettina Schmid

    Published 2024-06-01
    “…Molecular Neurodegeneration…”
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  5. 5
    Molecular and cellular characteristics of cerebrovascular cell types and their contribution to neurodegenerative diseases

    Molecular and cellular characteristics of cerebrovascular cell types and their contribution to neurodegenerative diseases by Francisco J. Garcia, Myriam Heiman

    Published 2025-01-01
    “…Molecular Neurodegeneration…”
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  6. 6
    Distinct regulation of Tau Monomer and aggregate uptake and intracellular accumulation in human neurons

    Distinct regulation of Tau Monomer and aggregate uptake and intracellular accumulation in human neurons by Amir T. Marvian, Tabea Strauss, Qilin Tang, Benjamin J. Tuck, Sophie Keeling, Daniel Rüdiger, Negar Mirzazadeh Dizaji, Hossein Mohammad-Beigi, Brigitte Nuscher, Pijush Chakraborty, Duncan S. Sutherland, William A. McEwan, Thomas Köglsperger, Stefan Zahler, Markus Zweckstetter, Stefan F. Lichtenthaler, Wolfgang Wurst, Sigrid Schwarz, Günter Höglinger

    Published 2024-12-01
    “…Molecular Neurodegeneration…”
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  7. 7
    The transcription factor combination MEF2 and KLF7 promotes axonal sprouting in the injured spinal cord with functional improvement and regeneration-associated gene expression

    The transcription factor combination MEF2 and KLF7 promotes axonal sprouting in the injured spinal cord with functional improvement and regeneration-associated gene expression by Callan L. Attwell, Inés Maldonado-Lasunción, Ruben Eggers, Bastiaan A. Bijleveld, Ward M. Ellenbroek, Natascha Siersema, Lotte Razenberg, Dédé Lamme, Nitish D. Fagoe, Ronald E. van Kesteren, August B. Smit, Joost Verhaagen, Matthew R. J. Mason

    Published 2025-02-01
    “…Molecular Neurodegeneration…”
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  8. 8
    Disparate and shared transcriptomic signatures associated with cortical atrophy in genetic behavioral variant frontotemporal degeneration

    Disparate and shared transcriptomic signatures associated with cortical atrophy in genetic behavioral variant frontotemporal degeneration by Ting Shen, Jacob W. Vogel, Vivianna M. Van Deerlin, EunRan Suh, Laynie Dratch, Jeffrey S. Phillips, Lauren Massimo, Edward B. Lee, David J. Irwin, Corey T. McMillan

    Published 2025-02-01
    “…Molecular Neurodegeneration…”
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  9. 9
    Loss of MEF2C function by enhancer mutation leads to neuronal mitochondria dysfunction and motor deficits in mice

    Loss of MEF2C function by enhancer mutation leads to neuronal mitochondria dysfunction and motor deficits in mice by Ali Yousefian-Jazi, Suhyun Kim, Jiyeon Chu, Seung-Hye Choi, Phuong Thi Thanh Nguyen, Uiyeol Park, Min-gyeong Kim, Hongik Hwang, Kyungeun Lee, Yeyun Kim, Seung Jae Hyeon, Hyewhon Rhim, Hannah L. Ryu, Grewo Lim, Thor D. Stein, Kayeong Lim, Hoon Ryu, Junghee Lee

    Published 2025-02-01
    “…Molecular Neurodegeneration…”
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  10. 10
    APOE Christchurch enhances a disease-associated microglial response to plaque but suppresses response to tau pathology

    APOE Christchurch enhances a disease-associated microglial response to plaque but suppresses response to tau pathology by Kristine M. Tran, Nellie E. Kwang, Claire A. Butler, Angela Gomez-Arboledas, Shimako Kawauchi, Cassandra Mar, Donna Chao, Rocio A. Barahona, Celia Da Cunha, Kate I. Tsourmas, Zechuan Shi, Shuling Wang, Sherilyn Collins, Amber Walker, Kai-Xuan Shi, Joshua A. Alcantara, Jonathan Neumann, Duc M. Duong, Nicholas T. Seyfried, Andrea J. Tenner, Frank M. LaFerla, Lindsay A. Hohsfield, Vivek Swarup, Grant R. MacGregor, Kim N. Green

    Published 2025-01-01
    “…Molecular Neurodegeneration…”
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  11. 11
    Lewy body diseases and the gut

    Lewy body diseases and the gut by Timothy R. Sampson, Malú Gámez Tansey, Andrew B. West, Rodger A. Liddle

    Published 2025-01-01
    “…Molecular Neurodegeneration…”
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  12. 12
    Cell-specific transcriptional signatures of vascular cells in Alzheimer’s disease: perspectives, pathways, and therapeutic directions

    Cell-specific transcriptional signatures of vascular cells in Alzheimer’s disease: perspectives, pathways, and therapeutic directions by Soumilee Chaudhuri, Minyoung Cho, Julia C. Stumpff, Paula J. Bice, Özkan İş, Nilüfer Ertekin-Taner, Andrew J. Saykin, Kwangsik Nho

    Published 2025-01-01
    “…Molecular Neurodegeneration…”
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  13. 13
    Chitinase-3-like-1: a multifaceted player in neuroinflammation and degenerative pathologies with therapeutic implications

    Chitinase-3-like-1: a multifaceted player in neuroinflammation and degenerative pathologies with therapeutic implications by Pharaoh Fellow Mwale, Cheng-Ta Hsieh, Ting-Lin Yen, Jing-Shiun Jan, Rajeev Taliyan, Chih-Hao Yang, Wen-Bin Yang

    Published 2025-01-01
    “…Molecular Neurodegeneration…”
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  14. 14
    Cellular senescence induced by cholesterol accumulation is mediated by lysosomal ABCA1 in APOE4 and AD

    Cellular senescence induced by cholesterol accumulation is mediated by lysosomal ABCA1 in APOE4 and AD by Shaowei Wang, Boyang Li, Jie Li, Zhiheng Cai, Cristelle Hugo, Yi Sun, Lu Qian, Julia TCW, Helena C. Chui, Dante Dikeman, Isaac Asante, Stan G. Louie, David A. Bennett, Zoe Arvanitakis, Alan T. Remaley, Bilal E. Kerman, Hussein N. Yassine

    Published 2025-02-01
    “…Molecular Neurodegeneration…”
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  15. 15
    Lipidome disruption in Alzheimer’s disease brain: detection, pathological mechanisms, and therapeutic implications

    Lipidome disruption in Alzheimer’s disease brain: detection, pathological mechanisms, and therapeutic implications by Sijia He, Ziying Xu, Xianlin Han

    Published 2025-01-01
    “…Molecular Neurodegeneration…”
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  16. 16
    Aging-associated sensory decline and Alzheimer’s disease

    Aging-associated sensory decline and Alzheimer’s disease by Suji Hong, Seung-Hyun Baek, Mitchell K. P. Lai, Thiruma V. Arumugam, Dong-Gyu Jo

    Published 2024-12-01
    “…Molecular Neurodegeneration…”
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  17. 17
    Upregulated astrocyte HDAC7 induces Alzheimer-like tau pathologies via deacetylating transcription factor-EB and inhibiting lysosome biogenesis

    Upregulated astrocyte HDAC7 induces Alzheimer-like tau pathologies via deacetylating transcription factor-EB and inhibiting lysosome biogenesis by Jinwang Ye, Suyue Zhong, Huali Wan, Xing Guo, Xuanbao Yao, Qiong Liu, Liming Chen, Jian-Zhi Wang, Shifeng Xiao

    Published 2025-01-01
    “…Molecular Neurodegeneration…”
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  18. 18
    RNA-Targeting CRISPR/CasRx system relieves disease symptoms in Huntington’s disease models

    RNA-Targeting CRISPR/CasRx system relieves disease symptoms in Huntington’s disease models by Yingqi Lin, Caijuan Li, Yizhi Chen, Jiale Gao, Jiawei Li, Chunhui Huang, Zhaoming Liu, Wei Wang, Xiao Zheng, Xichen Song, Jianhao Wu, Jiaxi Wu, Oscar Junhong Luo, Zhuchi Tu, Shihua Li, Xiao-Jiang Li, Liangxue Lai, Sen Yan

    Published 2025-01-01
    “…Molecular Neurodegeneration…”
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  19. 19
    Genetic context modulates aging and degeneration in the murine retina

    Genetic context modulates aging and degeneration in the murine retina by Olivia J. Marola, Michael MacLean, Travis L. Cossette, Cory A. Diemler, Amanda A. Hewes, Alaina M. Reagan, Jonathan Nyandu Kanyinda, Daniel A. Skelly, Gareth R. Howell

    Published 2025-01-01
    “…Molecular Neurodegeneration…”
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  20. 20
    Positron emission tomography tracers for synucleinopathies

    Positron emission tomography tracers for synucleinopathies by Jie Xiang, Zhentao Zhang, Shengxi Wu, Keqiang Ye

    Published 2025-01-01
    “…Molecular Neurodegeneration…”
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