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2041
Synthesis, Structure, and Anticancerous Properties of Silver Complexes
Published 2013-01-01“…Although the “war on cancer” is now in its fourth decade and much progress has been made in categorizing the environmental causes and cellular and molecular biological basis for this dreaded disease, we still do not have a precise understanding of the differences between a cancer cell and its normal counterpart. …”
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2042
Genetic analysis of weak expression of ABO blood group antigens in neonates
Published 2025-01-01“…[Objective] To perform genetic analysis on samples with weak agglutination and mixed agglutination of ABO blood group antigens in neonates, and to investigate the molecular biological characteristics of ABO subtypes in neonates. …”
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2043
Identification of Pratylenchus coffeae as a causal agent of root rot disease in Sorghum bicolor in China
Published 2025-01-01“…Afterward, the GL-1 population of root-lesion nematodes was identified as P. coffeae through a combination of morphological, rDNA-ITS and rDNA-28 S D2-D3 region techniques for molecular biological identification. We also conducted greenhouse experiments to assess the parasitism and pathogenicity of GL-1 and four other P. coffeae populations on sorghum through pot inoculation. …”
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2044
Isolation and identification of the causal agent of gummy stem blight disease in Cucumis sativus caused by a bacterial pathogen in China
Published 2025-01-01“…Therefore, combined with morphological and molecular biological features, strain HlJ-3 was identified as B. subtilis. …”
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2045
Evaluation of Prognostic Factors Following Flow-Cytometric DNA Analysis after Cytokeratin Labelling: II. Cervical and Endometrial Cancer
Published 2002-01-01“…Especially DNA‐aneuploidy (DI>1.3) is one of the most important independent molecular biological prognostic factors. While diagnostic curettage we could identify risk patients even preoperatively by determination of the prognostic factors like histologic tumor type, grading, cervical involvement and DNA‐ploidy. …”
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2046
“Lung-on-a-chip” as an instrument for studying the pathophysiology of human respiration
Published 2024-12-01“…“Lung-on-a-chip” (LoC) is a microfluidic device, imitating the gas-fluid interface of the pulmonary alveole in the human lung and intended for pathophysiological, pharmacological and molecular-biological studies of the air-blood barrier in vitro. …”
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2047
Association Study between Folate Pathway Gene Single Nucleotide Polymorphisms and Gastric Cancer in Koreans
Published 2012-09-01“…Gastric cancer is ranked as the most common cancer in Koreans. A recent molecular biological study about the folate pathway gene revealed the correlation with a couple of cancer types. …”
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2048
CLINICAL IMMUNOLOGY AND ALLERGOLOGY AS AN IMPORTANT COMPONENT OF CONTINUOUS MEDICAL EDUCATION OF DOCTORS
Published 2022-12-01“…The analysis of theoretical data shows that doctors, clinical immunologists, allergists, and specialists of related disciplines increasingly use the developments of the latest molecular-biological and hybridoma technologies in daily practical activities, which enables personalized approaches to the diagnosis of diseases and targeted therapy. …”
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2049
Preventive Effect of Liupao Tea Polyphenols on HCl/Ethanol-Induced Gastric Injury in Mice
Published 2020-01-01“…After a model of gastric injury in mice was established, mouse serum and tissues were analyzed by biochemical and molecular biological methods. The results showed that Liupao tea polyphenols (LTPs) could effectively reduce the area of gastric mucosal lesions, decrease the volume of gastric juice, and increase the pH of gastric juice in mice with gastric injury. …”
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2050
Irisin reshapes bone metabolic homeostasis to delay age-related osteoporosis by regulating the multipotent differentiation of BMSCs via Wnt pathway
Published 2025-01-01“…Nonetheless, the targeting effect of irisin on age-related osteoporosis and its underlying molecular biological mechanisms remain unclear.MethodsThe specific role of irisin in osteogenic-adipogenic differentiation in young or aging BMSCs was evaluated by multiple cells staining and quantitative real-time PCR (RT-qPCR) analysis. …”
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2051
Development of a duplex real-time recombinase aided amplification assay for the simultaneous and rapid detection of PCV3 and PCV4
Published 2025-02-01“…Results The established assay was more convenient and simpler operation compared with conventional molecular biological assays. The assay achieved a detection limit of 73.67 copies/reaction for each circovirus (at 95% probability by probit regression analysis) and showed high specificity and no cross-reactivity with other important porcine viruses (including PCV2). …”
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2052
Smaller sizes of polyethylene terephthalate microplastics mainly stimulate heterotrophic N2O production in aerobic granular sludge systems
Published 2025-05-01“…In this study, the effects of PET MPs with two common particle sizes of effluent from WWTPs (0.1 and 0.5 mm) on N2O turnovers, production pathways and N2O-sink capability were systematically disclosed in AGS systems by a series of biochemical tests and molecular biological means to achieve the goal of carbon neutrality. …”
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2053
Scientific support to plant breeding and seed production in Siberia in the XXI century
Published 2021-07-01“…The need for the introduction of modern molecular biological methods, bioengineering and IT technology is demonstrated and discussed. …”
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2054
<i>Macrostomum lignano</i> as a model to study the genetics and genomics of parasitic flatworms
Published 2021-03-01“…Parasitic flatworms have complex life cycles, are laborious and expensive in culturing, and have a range of anatomic and physiological adaptations that complicate the application of standard molecular-biological methods. On the other hand, free-living flatworm species, evolutionarily close to parasitic flatworms, do not have the abovementioned diff iculties, which makes them potential alternative models to search for and study homologous genes. …”
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2055
Comparative Study on Muscle Fiber Types of Longissimus Dorsi of Xinjiang Brown Cattle and Angus Cattle of Different Months
Published 2022-01-01“…The muscle histological and molecular biological reasons for the quality difference between Xinjiang brown cattle and Angus beef were discussed. …”
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2056
Association of Autoantibodies against M2-Muscarinic Acetylcholine Receptor with Atrial Fibrosis in Atrial Fibrillation Patients
Published 2019-01-01“…Left atrial appendages were subjected to histological and molecular biological assays. Patients in the AF group received follow-up for two years. …”
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2057
Deciphering CSU pathogenesis: Network toxicologyand molecular dynamics of DOTP exposure
Published 2025-02-01“…Conclusion: This study clarifies the potential molecular mechanisms of DOTP-induced CSU and underscores the efficacy of network toxicology, molecular docking, and molecular dynamics simulations in assessing the toxicity of food and environmental pollutants and their related molecular biological mechanisms. These findings offer new insights for future research, enhance our comprehension of the potential health impacts of food and environmental pollutants, and establish a scientific foundation for the development of prevention and treatment strategies.…”
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2058
A novel strategy for the protective effect of ginsenoside Rg1 against ovarian reserve decline by the PINK1 pathway
Published 2025-12-01“…Although ginsenoside Rg1 is known to modulate mitophagy, its effectiveness in mitigating ovarian reserve decline remains unclear.Objective To investigate the role of ginsenoside Rg1 in promoting mitophagy to preserve ovarian reserve.Materials and methods Ovarian reserve function, reproductive capacity, oxidative stress levels, and mitochondrial function were compared between ginsenoside Rg1-treated and untreated naturally aged female Drosophila using behavioral, histological, and molecular biological techniques. The protective effects of ginsenoside Rg1 were analyzed in a Drosophila model of oxidative damage induced by tert-butyl hydroperoxide. …”
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2059
MicroRNA-451a is a candidate biomarker and therapeutic target for major depressive disorder
Published 2024-02-01“…Eight-week-old male C57BL/6 mice had miR-451a overexpression in the medial prefrontal cortex (mPFC) via adeno-associated virus serotype 9 vectors encoding a pri-mmu-miR-451a-GFP fusion protein followed by behavioural and pathological analyses. Finally, molecular biological experiments were conducted to investigate the potential mechanism of miR-451a against depression.Results The serum levels of miRNA-451a were significantly lower in patients with MDD, with a negative correlation with the Hamilton Depression Scale scores. …”
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2060
QRFP43 modulates the activity of the hypothalamic-pituitary-thyroid axis in female sheep
Published 2025-01-01“…Hypothalamic, pituitary and thyroid glands were collected and preserved for further immunohistochemical and molecular biological analyses. Additionally, blood samples were collected during the experiment for subsequent RIA determinations. …”
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