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Drosophila Models of Parkinson's Disease: Discovering Relevant Pathways and Novel Therapeutic Strategies
Published 2011-01-01“…Among them, Drosophila has emerged as a very valuable model organism in the study of either toxin-induced or genetically linked PD. …”
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22
Reducing maladaptive behavior in neuropsychiatric disorders using network modification
Published 2025-01-01“…In this proof-of-concept computational psychiatry study, we tested this approach in a simple model organism that is controlled by a neural network and that exhibits aversion-resistant alcohol drinking – a key maladaptive behavior associated with alcohol use disorder. …”
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23
Cross-species comparison of AlphaFold-derived G protein-coupled receptor structures reveals novel melatonin-related receptor in Neurospora crassa.
Published 2025-01-01“…This proof-of-concept study underscores the potential of N. crassa as a model organism for circadian research and demonstrates the broader applicability of using AlphaFold2, especially when sequence similarity does not lead to candidate genes, for identifying novel receptors across different species.…”
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24
Egg Microinjection for the Ladybird Beetle Harmonia axyridis
Published 2024-12-01“…H. axyridis is an emerging model organism for studying various biological fields, showing intraspecific polymorphisms exhibiting highly diverse color patterns on the elytra. …”
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25
Nematicidal Action of Microencapsulated Essential Oil of Flesh Fingered Citron
Published 2020-01-01“…Using Caenorhabditis elegans as a model organism, we explored the toxicity of (1) FFC EO microcapsules (MCs) and (2) four key compounds of the EOs. …”
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26
Comprehensive toxicity assessment of silver nanoparticles on Bacteria, human vein endothelial cells, and Caenorhabditis Elegans
Published 2025-03-01“…In this study, it was investigated the effects of AgNPs on bacteria (Escherichia coli and Bacillus subtilis), a model organism (Caenorhabditis elegans), and human vein endothelial cells (HUVECs) at low concentrations (10, 30, and 50 μg/mL).The AgNPs were synthesized using a chemical reduction method and thoroughly characterized, showing a hydrodynamic size of 55 nm, a zeta potential of −57 mV, and thermal decomposition temperatures ranging from 182 to 318 °C. …”
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27
Culturable Bacterial Communities Related to Different Larval Stages of Sanys irrosea (Guenee, 1852) (Lepidoptera: Noctuoidae)
Published 2022-12-01“…In this study, we purposed to isolate and identify the culturable bacterial species in internal organs (mostly gut parts) of Sanys irrosea (Guenee, 1852) (Lepidoptera: Noctuidae) which was selected as model organism. The bacterial flora of different development stages of S. irrosea was studied by culture dependent techniques and the isolated bacteria was identified by 16S rRNA sequencing and phylogenetic analysis. …”
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28
Harnessing Insect Chemosensory and Mechanosensory Receptors Involved in Feeding for Precision Pest Management
Published 2025-01-01“…This review highlights recent advancements in research on feeding-related sensory receptors, covering a wide range of insect species, from the model organism <i>Drosophila melanogaster</i> to agricultural and human pests. …”
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29
Zebrafish as a model for human epithelial pathology
Published 2025-02-01“…The advantages of using zebrafish as a model organism include rapid external development, ease of genetic manipulation, and advanced imaging capabilities, allowing for the real-time observation of disease processes. …”
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Modelling Peroxisomal Disorders in Zebrafish
Published 2025-01-01“…The zebrafish (<i>Danio rerio</i>) has become an attractive vertebrate model organism to investigate peroxisomal functions. Here, we provide an overview of the visualisation of peroxisomes in zebrafish, as well as the peroxisomal metabolic functions and peroxisomal protein inventory in comparison to human peroxisomes. …”
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31
Covariation Between Microbiome Composition and Host Transcriptome in the Gut of Wild Drosophila melanogaster: A Re‐Analysis
Published 2025-01-01“…The fruitfly Drosophila melanogaster is a preeminent model organism, amenable to field investigation by ‘omic analyses. …”
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32
Yeast as a Tool to Study Signaling Pathways in Mitochondrial Stress Response and Cytoprotection
Published 2012-01-01“…The yeast Saccharomyces cerevisiae has proven a valuable model organism in which several intracellular processes have been characterized in great detail, including the retrograde response to mitochondrial dysfunction and, more recently, programmed cell death. …”
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Divergent effects of entomopathogenic fungi and medicinal mushroom species on Drosophila melanogaster lifespan
Published 2024-12-01“…On the contrary, L. edodes showed a remarkable lifespan-extending effect on the model organism, with fruit fly individuals surviving for 55 culture days. …”
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34
Evaluation of the Hair Cell Regeneration in Zebrafish Larvae by Measuring and Quantifying the Startle Responses
Published 2017-01-01“…The zebrafish has become an established model organism for the study of hearing and balance systems in the past two decades. …”
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35
Seroprevalence of <i>Toxoplasma gondii</i> in White-Tailed Deer (<i>Odocoileus virginianus</i>) in New York State
Published 2025-01-01“…The parasitic protozoa, <i>Toxoplasma gondii</i> (<i>T. gondii</i>), is a model organism for one health because of its wide-ranging impacts on humans, wildlife, and domestic animals. …”
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Mutations of the Electron Transport Chain Affect Lifespan and ROS Levels in <i>C. elegans</i>
Published 2025-01-01“…Using <i>Caenorhabditis elegans</i> as a model organism, we discuss how ETC mutations manifest as developmental abnormalities, lifespan alterations, and changes in mtROS levels. …”
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37
Application of in vitro and in vivo models in the study of food allergy
Published 2018-12-01“…We also introduced zebrafish, a promising model organism for investigating immunity though lacking direct applications in food allergy to date, and focused on traumatic inflammation, bacterial infection and viral infection models. …”
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Toxic Effect and Molecular Mechanism of Arsenolipids on Promoting Aging in Caenorhabditis elegans
Published 2024-12-01“…In this study, we explored the effect of two arsenolipids with different molecular masses, AsHC 332 and AsHC 346, which are commonly found in seafood, on aging and lifespan-related indicators in the model organism Caenorhabditis elegans. The possible mechanism by which the arsenolipids promote aging was analyzed by measuring the expression of DAF-16 protein in the nematode, the longevity of aging mutants and stress-related genes. …”
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39
Investigation of non-alcoholic steatohepatitis in labidochromis caeruleus and xiphophorus hellerii
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40
Evolutionary patterns of the SSU rRNA (V4 region) secondary structure in genus Euplotes (Ciliophora, Spirotrichea): insights into cryptic species and primitive traits
Published 2025-01-01“…The genus Euplotes, a group of ciliated protists, has attracted attention as a model organism due to its widespread distribution and ease of cultivation. …”
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