Integrating rapamycin with novel PI3K/Akt/mTOR inhibitor microRNAs on NOTCH1-driven T-cell acute lymphoblastic leukemia (T-ALL) by Fateme Arjmand, Samaneh Shojaei, Mitra Khalili, Hossein Dinmohammadi, Behzad Poopak, Samira Mohammadi-Yeganeh, Yousef Mortazavi

Subjects: Get full text

Protective Effects of NaHS/miR-133a-3p on Lipopolysaccharide-Induced Cardiomyocytes Injury by Yi-Mei Jin, Ai-Rong Huang, Mei-qian Yu, Wan-Ding Ye, Xiao-guang Hu, Hua-min Wang, Zhi-wei Xu, Dong-shi Liang

“…The second experiment added a fourth group, the LPS + NaHS + miR-133a-3p inhibition group, with the aim to preliminarily explore whether miR-133-3p exerts a protective function downstream of NaHS. …”
Get full text

Stability of miR-126 in Urine and Its Potential as a Biomarker for Renal Endothelial Injury with Diabetic Nephropathy by Yang Liu, Guangqiang Gao, Chun Yang, Kun Zhou, Baozhong Shen, Hongyan Liang, Xiaofeng Jiang

“…The purpose of the present study was to assess the feasibility of using miR-126 in the urine as a biomarker for diabetic nephropathy. …”
Get full text

circRNA18_46222157_46248185 inhibits melanogenesis by targeting miR-211/ pathway in goat melanocytes by Kai Yuan Ji, Xue Qing Zhang, Yi Wei Zhao, Chun E Liang, Xin Yuan, Yun Hai Zhang

“…Overexpression of miR-211 in melanocytes significantly augmented (p<0.01) melanin production. …”
Get full text

The Expression of miR-192 and Its Significance in Diabetic Nephropathy Patients with Different Urine Albumin Creatinine Ratio by Xiaoyu Ma, Canlu Lu, Chuan Lv, Can Wu, Qiuyue Wang

“…To investigate the expression of miR-192 and its significance in diabetic nephropathy (DN) patients. …”
Get full text

Hsa-miR-105-1 Regulates Cisplatin-Resistance in Ovarian Carcinoma Cells by Targeting ANXA9 by Xinxin Kou, Hui Ding, Lei Li, Hongtu Chao

“…In this study, we examined how Hsa-miR-105-1 functions in cisplatin-resistant OC cells. …”
Get full text

miR-21 Overexpression Promotes Esophageal Squamous Cell Carcinoma Invasion and Migration by Repressing Tropomyosin 1 by Zhuojian Shen, Xia Xu, Liangzhan Lv, Honglue Dai, Ju Chen, Baishen Chen

“…Inhibition of miR-21 reduced migration and invasion in two ESCC cell lines, and overexpression of miR-21 promoted migration and invasion in vitro. …”
Get full text

miR-141-3p is Poorly Expressed in Polycystic Ovary Syndrome and Correlates with Glucose and Lipid Metabolism by Lingye Fan, Chunyan Wang, Ping Zhan, Yaofang Liu

“…Polycystic ovary syndrome (PCOS) is a common endocrinopathy with high prevalence. miR-141-3p downregulation was reported in PCOS rats. …”
Get full text

miR-1233-3p Inhibits Angiopoietin-1-Induced Endothelial Cell Survival, Migration, and Differentiation by Veronica Sanchez, Sharon Harel, Anas Khalid Sa’ub, Dominique Mayaki, Sabah N. A. Hussain

“…Moreover, miR-1233-3p overexpression resulted in reversal of the anti-apoptotic, pro-migration, and pro-differentiation effects of Ang-1. …”
Get full text

Intranasal Delivery of miR-146a Mimics Delayed Seizure Onset in the Lithium-Pilocarpine Mouse Model by Hua Tao, Jianghao Zhao, Tingting Liu, Yujie Cai, Xu Zhou, Huaijie Xing, Yan Wang, Mingkang Yin, Wangtao Zhong, Zhou Liu, Keshen Li, Bin Zhao, Haihong Zhou, Lili Cui

“…Unveiling the key mechanism of temporal lobe epilepsy (TLE) for the development of novel treatments is of increasing interest, and anti-inflammatory miR-146a is now considered a promising molecular target for TLE. …”
Get full text

circ_0001588 Induces the Malignant Progression of Hepatocellular Carcinoma by Modulating miR-874/CDK4 Signaling by Xiaoyun Bin, Yichen Chen, Jiasheng Ma, Renchao Tang, Zhenrong Zhao, Kangxuan Wang, Jianchu Wang

“…Using luciferase binding assays, we proved that circ_0001588 functions as a molecular ceRNA of miR-874 and that CDK4 acts as a downstream target of miR-874 in HCC. …”
Get full text

LINC00707 Regulates miR-382-5p/VEGFA Pathway to Enhance Cervical Cancer Progression by Hua Guo, Jing Li, Furong Fan, Ping Zhou

“…Subsequently, lack of VEGFA expression reversed the influence of miR-382-5p knockdown on cervical cancer cells. In conclusion, our findings evidenced the significant role of LINC00707-miR-382-5p-VEGFA network in cervical cancer and it can provide an attractive target.…”
Get full text

DNA Methylation Is Involved in the Expression of miR-142-3p in Fibroblasts and Induced Pluripotent Stem Cells by Siti Razila Abdul Razak, Yukihiro Baba, Hiromitsu Nakauchi, Makoto Otsu, Sumiko Watanabe

“…Loss-of-function analyses of miR-142-3p suggested that miR-142-3p plays roles in the proliferation and differentiation of induced pluripotent stem cells. …”
Get full text

miR-24-3p/KLF8 Signaling Axis Contributes to LUAD Metastasis by Regulating EMT by Pengyu Jing, Nianlin Xie, Nan Zhao, Ximing Zhu, Pei Li, Guizhou Gao, Haizhou Dang, Zhongping Gu

“…This study explored the functions and mechanisms of miR-24-3p/KLF8 signaling in advanced LUAD. The expression level of miR-24-3p and KLF8 were tested in LUAD patients, and the corelation of miR-24-3p and KLF8 was evaluated. …”
Get full text

Was mir wichtig war, wurde und ist. Bücher, Publikationen, Dokumente nicht nur musiktheoretisch-musikwissenschaftlicher Herkunft by Hartmut Fladt

Get full text

miR-504 Promoted Gastric Cancer Cell Proliferation and Inhibited Cell Apoptosis by Targeting RBM4 by Yi Zhang, Hongmei Yong, Jing Fu, Guangyi Gao, Huichang Shi, Xueyi Zhou, Mingsheng Fu

“…The purpose of this study was to explore the role and underlying mechanism of miR-504 and RBM4 in gastric cancer. Methods. The qRT-PCR or Western blot was performed to determine the expressions of miR-504 and RBM4 in the gastric cancer tissues and normal tissues. …”
Get full text

Elevation of Circulating miR-210 Participates in the Occurrence and Development of Type 2 Diabetes Mellitus and Its Complications by Xi Chen, Feng Tian, Zhilian Sun, Guoqing Zeng, Ping Tang

“…This study is aimed at analyzing the correlation of circulating miR-210 level and obesity-associated T2DM and then investigating the underlying mechanism of circulating miR-210 in T2DM. …”
Get full text

miR-21 and cathepsin B in familial Mediterranean fever: novel findings regarding their impact on disease severity by Emrah Yucesan, Mehmet Yildiz, Ramila Hajiyeva

“…Only miR-21-5p was negatively correlated with IL-1β (r=−0.855; p&lt;0.001). …”
Get full text

miR-142 deficit in T cells during blast crisis promotes chronic myeloid leukemia immune escape by Fang Chen, Dandan Zhao, Yongfang Xu, Yi Zhang, Min-Hsuan Chen, Khyatiben V. Pathak, Nate Hansen, Brooke Lovell, Yong Liang, Katrina Estrella, Wei-Le Wang, Lucy Ghoda, Russell Rockne, Xiwei Wu, Haris Ali, Jianhua Yu, Michael A. Caligiuri, Stephen J. Forman, Jeff M. Trent, Ya-Huei Kuo, Ling Li, Piotr Swiderski, Jianying Zhang, Marcin Kortylewski, Le Xuan Truong Nguyen, Patrick Pirrotte, Mark Boldin, Guido Marcucci, Bin Zhang

“…Abstract We reported that an acquired miR-142 deficit transforms chronic phase (CP) chronic myeloid leukemia (CML) leukemic stem cells (LSCs) into blast crisis (BC) LSCs. …”
Get full text