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1061
A comparative analysis of global and Chinese trends in the burden of kidney cancer from 1990 to 2021
Published 2025-02-01“…Additionally, the age-standardized rate of kidney cancer in males was notably higher than in females, particularly among middle-aged males. The (1-MIR) of renal cancer increased from 0.36 to 0.62 in China and from 0.49 to 0.58 globally. …”
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1062
Downregulation of LPAR1 Promotes Invasive Behavior in Papillary Thyroid Carcinoma Cells
Published 2024-09-01“…LPAR1 expression correlated positively with immune infiltrates such as CD4 + T cells, macrophages, neutrophils, and myeloid dendritic cells but negatively with B cells. Additionally, miR-221-5p was predicted to target LPAR1 in PTC. …”
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1063
An Integrating Approach for Genome-Wide Screening of MicroRNA Polymorphisms Mediated Drug Response Alterations
Published 2017-01-01“…We developed a user-friendly online database of this approach named Mir2Drug.…”
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1064
Predicting the Progress of Tuberculosis by Inflammatory Response-Related Genes Based on Multiple Machine Learning Comprehensive Analysis
Published 2023-01-01“…The results of the miRNA–genes network analysis suggested a potential role of hsa-miR-3163 in the molecular mechanism of LTBI progressing into ATB. …”
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1065
Comparative analysis of the whole transcriptome landscapes of muscle and adipose tissue in Qinchuan beef cattle
Published 2025-01-01“…Among them, 55 ceRNA axes were involved, including circRNA12990 - bta-miR-133a_L-1R + 1 - MYO6/ZEB2, circRNA2893/MSTRG.28538.1/MSTRG.11613.4 - pma-miR-145-5p_R + 2 - EYA4 and MSTRG.26982.1 - bta-let-7e_R + 1 - RBM40. …”
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1066
To Develop Biomarkers for Diabetic Nephropathy Based on Genes Related to Fibrosis and Propionate Metabolism and Their Functional Validation
Published 2024-01-01“…Moreover, 8 TFs, 60 miRNAs, and 7 mRNAs formed the TF–miRNA–mRNA regulatory network, including USF1-hsa-mir-1296-5p-AGT and HIF1A-hsa-mir-449a-5p-ACE2. …”
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1067
Development of novel nucleic acid therapy aimed at directly controlling liver fibrosis
Published 2025-03-01“…Previously, we have shown that treatment with miR-29a-3p improved liver fibrosis in a mouse model. …”
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1068
Efficacy of Shenqi Pollen Capsules for High-Altitude Deacclimatization Syndrome via Suppression of the Reoxygenation Injury and Inflammatory Response
Published 2019-01-01“…SPC therapy also reduced the serum levels of CK, CK-MB, LDH, IL-17A, TNF-α, and miR-155 and elevated IL-10 and miR-21 levels. We thus demonstrate that SPCs effectively ameliorated HADAS symptoms in these subjects via suppression of the hypoxia-reoxygenation injury and inflammatory response.…”
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1069
红景天苷调控<italic>miRNA-1343-3p/MAP3K6/MMP24</italic>信号分子抑制胃癌细胞的增殖和侵袭
Published 2023-07-01“…目的本研究旨在探讨红景天苷调控<italic>miR-1343-3p</italic>/<italic>MAP3K6</italic>(丝裂原激活激酶激酶激酶6)/<italic>MMP24</italic>(膜型基质金属蛋白酶24)信号分子,在抑制胃癌细胞增殖和迁移中的作用。…”
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1070
Circulating MicroRNAs in Patients with Psoriasis Treated with Anti-IL-23: A Cohort Study
Published 2025-01-01“…Conclusions This study identifies specific circulating miRNAs, including miR-200a-3p, as potential biomarkers for monitoring treatment responses in psoriasis patients. …”
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1071
Integrating Genomic Selection and a Genome-Wide Association Study to Improve Days Open in Thai Dairy Holstein Cattle: A Comprehensive Genetic Analysis
Published 2024-12-01“…For the GWAS, we found 12 potential candidate genes (<i>DYRK1A</i>, <i>CALCR</i>, <i>MIR489</i>, <i>MIR653</i>, <i>SLC36A1</i>, <i>GNA14</i>, <i>GNAQ</i>, <i>TRNAC-GCA</i>, <i>XYLB</i>, <i>ACVR2B</i>, <i>SLC22A14</i>, and <i>EXOC2</i>) that are believed to have a significant influence on days open. …”
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1072
Identifying a Serum Exosomal-Associated lncRNA/circRNA-miRNA-mRNA Network in Coronary Heart Disease
Published 2021-01-01“…The LncRNA/circRNA-miRNA-mRNA interaction axes (RPL7AP11/hsa-miR-17-5p/UBC and RPL7AP11/hsa-miR-20b-5p/UBC) were obtained from the network. …”
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1073
TET1 is a Tumor Suppressor That Inhibits Papillary Thyroid Carcinoma Cell Migration and Invasion
Published 2020-01-01“…The knockdown of the TET1 gene promoted cell migration and invasion in BCPAP cells. The expression of miR-7, miR-15/16 cluster, and let-7 family was downregulated, while the expression of let-7e was upregulated after siRNA-TET1 treatment in BCPAP cells. …”
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1074
New bitongling regulates gut microbiota to predict angiogenesis in rheumatoid arthritis via the gut-joint axis: a deep neural network approach
Published 2025-02-01“…Additionally, NBTL upregulated miR-20a-5p and miR-223-3p, contributing to its anti-angiogenic effects.ConclusionNBTL exhibits significant therapeutic potential in RA by modulating gut microbiota and inhibiting the VEGF signaling pathway. …”
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1075
MEL-IRIS: An Online Tool for Audio Analysis and Music Indexing
Published 2009-01-01“…Especially in Music Information Retrieval (MIR), the visualization of the chromatic analysis can be used for comparison, pattern recognition, melodic sequence prediction, and color-based searching. …”
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1076
The anti-cancerous mechanism of licochalcone A on human hepatoma cell HepG2 based on the miRNA omics
Published 2023-07-01“…Afterwards, the miRNA-target networks were established to screen key dysregulated miRNAs. Two key miRNAs (hsa-miR-133b and hsa-miR-145-5p) were filtered. Finally, the miRNA-target-transcription factor networks were constructed for these key miRNAs. …”
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1077
A Circulating miRNA-Based Scoring System Established by WGCNA to Predict Colon Cancer
Published 2019-01-01“…Among all these hub genes, hsa-miR-23a-3p (OR=2.6391, p=6.23×10‐5) and hsa-miR-663a (OR=1.4220, p=0.0069) were identified as an independent risk factor of colon cancer by multivariate regression. …”
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1078
A Novel Type of Non-coding RNA, nc886, Implicated in Tumor Sensing and Suppression
Published 2015-06-01“…nc886 (=vtRNA2-1, pre-miR-886, or CBL3) is a newly identified non-coding RNA (ncRNA) that represses the activity of protein kinase R (PKR). nc886 is transcribed by RNA polymerase III (Pol III) and is intriguingly the first case of a Pol III gene whose expression is silenced by CpG DNA hypermethylation in several types of cancer. …”
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1079
Age Discrimination of Chinese Baijiu Based on Midinfrared Spectroscopy and Chemometrics
Published 2021-01-01“…In this paper, the raw and mellow Baijiu samples from different storage time are discriminated accurately throughout midinfrared (MIR) spectroscopy and chemometrics. Firstly, changing regularities of the substances in Chinese Baijiu are discussed by gas chromatography-mass spectrometry (GC-MS) during the aging process. …”
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1080
Experimental Studies on the Changes in Resistivity and Its Anisotropy Using Electrical Resistivity Tomography
Published 2012-01-01“…Apparent resistivity data were acquired by MIR-2007 resistivity meter when samples were under uniaxial compression of servocontrol YAW-5000F loadingmachine in laboratory. …”
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