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1001
Polarization conversion in soft glass fluoride and chalcogenide fibers for mid-infrared applications
Published 2025-01-01“…Mid-infrared (MIR) technologies are crucial for applications from chemical sensing to precision medical surgery. …”
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1002
Construction and Investigation of MicroRNA-mRNA Regulatory Network of Gastric Cancer with Helicobacter pylori Infection
Published 2020-01-01“…Patients with higher expression of hsa-miR-196b-3p, CALML4, or SMAD6 or lower expression of PITX2 or TGFB2 had better outcomes than those with lower expression of hsa-miR-196b-3p, CALML4, or SMAD6 or higher expression of PITX2 or TGFB2 (P<0.05). …”
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1003
Matrix Metalloproteinase‐Responsive Controlled Release of Self‐Assembly Nanoparticles Accelerates Heart Valve Regeneration In Situ by Orchestrating Immunomodulation
Published 2025-01-01“…Specifically, galactose‐modified human serum albumin nanoparticles (miR‐93@HSA NPs) to deliver microRNA‐93 mimics are utilized, which target macrophages and induce their differentiation into the anti‐inflammatory M2 subtype, fostering a conducive immune microenvironment. …”
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1004
Impact of 17-alpha ethinyl estradiol (EE2) and diethyl phthalate (DEP) exposure on microRNAs expression and their target genes in differentiated SH-SY5Y cells
Published 2025-01-01“…Our results show that both EDCs downregulated specific miRNAs—miR-18b-5p, miR-200a-3p, and miR-653-5p—affecting key processes such as cell proliferation, survival, and apoptosis. …”
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1005
Integrated analysis of transcriptome, sRNAome, and degradome involved in the drought-response of maize Zhengdan958
Published 2025-01-01“…Tissue-specific expression profile and regulatory network analysis revealed that miR528a/b-Zm00001d021850, miR408a/b-Zm00001d020794, and miR164e-Zm00001d003414 might be essential in root-specific drought stress response of maize Zhengdan958 seedlings. …”
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1006
Role of B7H4 and Fas in regulation of trophoblast cells and development of pre-eclampsia: a cross-sectional study
Published 2025-12-01“…Overexpression of B7H4 alleviated the inhibitory effects of miR-4319, which were reversed by Fas knockdown (p < 0.05).Conclusions miR-4319 mediates the progression of trophoblast progression by negatively regulating the expression of B7H4 and Fas. …”
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1007
Urinary Proteome and Exosome Analysis Protocol for the Discovery of Respiratory Diseases Biomarkers
Published 2025-01-01“…We could confirm the expression of miRNAs previously connected to respiratory diseases (i.e., miR-16-5p, miR-21-5p, miR-146a-5p, and miR-215-5p) in urine exosomes by RTqPCR. …”
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1008
Inhibition of Glycogen Synthase Kinase and the Neuroprotective Function of Conjugated ZnO-Osthol Nanoparticles in Alzheimer’s Disease
Published 2022-01-01“…The key reason was that by upregulating miR-132, osthol could inhibit APP expression to prevent AD from occurring.…”
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1009
hsa_circWDR37_016 Regulates Hypoxia-Induced Proliferation of Pulmonary Arterial Smooth Muscle Cells
Published 2022-01-01“…Furthermore, bioinformatics and Luciferase assay showed that circWDR37 directly sponged hsa-miR-138-5p (miR-138) and was involved in the immunoregulatory and inflammatory processes of PAH. …”
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1010
Inferring single-cell and spatial microRNA activity from transcriptomics data
Published 2025-01-01“…We also show miR-519a-3p differential activity in specific cell populations.…”
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1011
Liver Expression of Sulphotransferase 2A1 Enzyme Is Impaired in Patients with Primary Sclerosing Cholangitis: Lack of the Response to Enhanced Expression of PXR
Published 2015-01-01“…Transcription of SULT2A1 gene is induced by pregnane-X-receptor (PXR) and can be repressed by miR-378a-5p. We studied the PXR/SULT2A1 axis in chronic cholestatic conditions: primary sclerosing cholangitis (PSC) and primary biliary cirrhosis (PBC). …”
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1012
Identification of HOXA9 methylation as an epigenetic biomarker predicting prognosis and guiding treatment choice in acute myeloid leukemia
Published 2025-02-01“…Bioinformatics analysis demonstrated the association of HOXA9 expression with diverse leukemia-related genes (HOXAs, SOSTDC1, MEG3, miR-10a, miR-381 and miR-193b) and signaling pathways (PI3K-Akt signaling) in AML. …”
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1013
Transcriptome, miRNA, and degradome sequencing reveal the leaf stripe (Pyrenophora graminea) resistance genes in Tibetan hulless barley
Published 2025-01-01“…Using RNA-seq, small RNA sequencing (miRNA-seq) combined with degradome sequencing (degradome-seq), four pairs associated with leaf-stripe miRNAs and target genes were obtained, namely Hvu-miR168-5p and Argonaute1 (HvAGO1), Hvu-novel-52 and growth-regulating factor 6 (HvGRF6), Hvu-miR6195 and chemocyanin-like protein (CLP), and Hvu-miR159b and gibberellin-dependent MYB (GAMYB). …”
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1014
miRNAs in Extracellular Vesicles from iPS-Derived Cardiac Progenitor Cells Effectively Reduce Fibrosis and Promote Angiogenesis in Infarcted Heart
Published 2019-01-01“…Amongst the highly enriched miRNAs, miR-373 was strongly antifibrotic, targeting 2 key fibrogenic genes, GDF-11 and ROCK-2. miR-373 mimic itself was highly efficacious in preventing scar formation in the infarcted myocardium. …”
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1015
Antioxidant, antimicrobial, and anticancer effects of Achillea filipendulina L. against colon cancer
Published 2024-12-01“…A significant increase in miR-519d expression was observed in HT29 cells, while a decrease in Dvl-1 expression was noted. …”
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1016
Comecon as the «Core» of Alternative Globalization
Published 2021-06-01“…Book review: «The World System of Socialism» and the Global Economy in the mid-1950s – mid-1970s/ ed. by M.A. Lipkin. Moscow: Ves’ mir, 2019.…”
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1017
Macrophage Notch1 signaling modulates regulatory T cells via the TGFB axis in early MASLD
Published 2025-01-01“…Consistently, HFD-fed Notch1M-KO mice exhibited reduced miR-142a-3p levels, elevated TGFBR1 expression on T cells, and increased Treg frequency in the liver. …”
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1018
Associations between milk infrared-predicted plasma biomarkers of stress resilience and fertility in dairy cattle: Insights for enhancing breeding programs and herd management
Published 2025-02-01“…The 2 databases were merged according to the milk test day (and thus, the MIR spectrum) closest to the date of insemination. …”
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1019
Diagnostic Role of Plasma MicroRNA-21 in Stable and Unstable Angina Patients and Association with Aging
Published 2020-01-01“…Total RNA was extracted from plasma by using miRNA-based TRIzol reagent. Plasma miR-21 expression levels were determined by real-time polymerase chain reaction. …”
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1020
MiRNA target enrichment analysis of co-expression network modules reveals important miRNAs and their roles in breast cancer progression
Published 2024-12-01“…Also, we use negative correlation between miRNA expression and modules as the second filter to ensure choosing the right candidate miRNAs regarding to important modules. We found hsa-mir-23b, hsa-let-7b and hsa-mir-30a are important miRNAs in breast cancer and also investigated their roles in breast cancer progression.…”
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