Application and Evaluation of [Tc]-Labeled Peptide Nucleic Acid Targeting in Breast Cancer Imaging by Yaqun Jiang MD, Yongkang Gai PhD, Yu Long MD, Qingyao Liu PhD, Chunbao Liu MD, PhD, Yongxue Zhang MD, Xiaoli Lan MD, PhD

“…In this study, a PNA sequence that undergoes complementary binding to miR-155 was labeled with 99m Tc to evaluate whether the tracer could visualize the expression of miR-155 in breast cancer. …”
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Moxibustion Regulates the BRG1/Nrf2/HO-1 Pathway by Inhibiting MicroRNA-222-3p to Prevent Oxidative Stress in Intestinal Epithelial Cells in Ulcerative Colitis and Colitis-Associat... by Xuejun Wang, Haiyang Ji, Yanting Yang, Dan Zhang, Xiehe Kong, Xiaoying Li, Hongna Li, Yunqiong Lu, Guang Yang, Jie Liu, Huangan Wu, Jue Hong, Xiaopeng Ma

“…The effect of HPM was inhibited in miR-222-3p overexpression mice, further demonstrating that the protective effect of HPM on UC and CAC mice was through inhibiting miR-222-3p. …”
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Plasma microRNA-145-5p as a diagnostic biomarker for acute deep vein thrombosis by Christopher Antoun, Vårin Eiriksdatter Wikan, Øyvind Øverli, Thor Ueland, Gholamreza Jafari Yeganeh, Sigrid Kufaas Brækkan, Ellen Brodin, John-Bjarne Hansen

“…Objectives: The aim of this study was to assess the diagnostic performance of miR-145 for the diagnosis of acute lower extremity DVT. …”
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乳腺癌差异表达的MicroRNA的筛选研究

“…【结果】 对芯片数据进行SAM分析,结果筛选获得16个乳腺癌相关miRNAs, 相对于癌旁组织,在乳腺癌组织中9个miRNAs表达上调,7个miRNAs表达下调。其中显著上调的有miR-21,miR-365,显著下调的有miR-497,miR-31。【结论】 筛选得到乳腺癌miRNA差异表达谱,其可能与乳腺癌的发生发展有关。…”
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Extracellular vesicles derived from creeping fat stem cells promote lymphatic function and restrain inflammation of Crohn's disease by Weigang Shu, Yongheng Wang, Mengfan Chen, Xiaoli Zhu, Fangtao Wang, Chunqiu Chen, Peng Du, Alexandra Bartolomucci, Xin Su, Xiaolei Wang

“…Moreover, serum miR‐132‐3p demonstrated a positive correlation with disease activity. …”
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Pediatric and adolescent cancer disparities in the Middle East and North Africa (MENA) region: incidence, mortality, and survival across socioeconomic strata by Ankita Shukla, Rouba Karen Zeidan, Basema Saddik

“…A negative correlation was observed between a country’s SDI and MIR (-0.797) and SDI and mortality rates (-0.547) indicating that higher SDI corresponds to lower MIR and lower mortality rates. …”
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MicroRNA-19a Targets Fibroblast Growth Factor-Inducible Molecule 14 and Prevents Tubular Damage in Septic AKI by Jun Hong, Bang-Chuan Hu, Liang Xu, Yang Zheng, Zi-Qiang Shao, Run Zhang, Xiang-Hong Yang, Ren-Hua Sun, Shi-Jing Mo

“…We identify Fn14 as a bona fide target of miR-19a, which directly binds to 3′ UTR of Fn14 for repression independent of cylindromatosis (CYLD), the deubiquitinase (DUB) downstream of miR-19a, and thereby antagonizes the LPS-induced tubular cell apoptosis. …”
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Optimizing therapeutic outcomes: preconditioning strategies for MSC-derived extracellular vesicles by Yuqi Song, Fengrui Liang, Weikun Tian, Erin Rayhill, Liping Ye, Xinghan Tian

“…Such conditioning is shown to optimize their therapeutic potential. Key miRNAs including miR-21, miR-146, miR-125a, miR-126, and miR-181a are particularly noted for their roles in facilitating tissue repair and modulating inflammatory responses. …”
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A Cross-Sectional Trait Versus State Biomarker Analysis of Inflammatory Cytokines and miRNAs in Patients with Major Depressive Disorder by Christopher Rockson, Chandrashekaran Girish, Harivenkatesh Natarajan, Vikas Menon

“…We quantified the gene expressions of plasma miR-16, miR-132, and miR-1202 using Quantitative Real Time-Polymerase Chain Reaction (qRT-PCR). …”
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miRNA-375 a Sensor of Glucotoxicity Is Altered in the Serum of Children with Newly Diagnosed Type 1 Diabetes by Lucien Marchand, Audrey Jalabert, Emmanuelle Meugnier, Kathleen Van den Hende, Nicole Fabien, Marc Nicolino, Anne-Marie Madec, Charles Thivolet, Sophie Rome

“…Downregulated miRNAs, including miR-375, were involved in pancreas secretion and protein turnover. …”
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血浆外泌体miRNAs与妊娠期糖尿病的关系 by 叶志鑫, 陈渡波, 陈培松, 林穗雯, 黄晓晴, 李诗琪, 刘斌

“…实时定量RT-PCR结果表明与NGT组相比，妊娠早期GDM孕妇血浆外泌体中hsa-miR-188-5p、hsa-miR-663a、hsa-miR-135a-5p和hsa-miR-4707-5p表达上调，4种miRNAs联合预测GDM的曲线下面积（AUC）为0.839（95% CI 0.724~0.954）。…”
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Analysis of Argonaute Complex Bound mRNAs in DU145 Prostate Carcinoma Cells Reveals New miRNA Target Genes by Jaroslaw Szczyrba, Volker Jung, Michaela Beitzinger, Elke Nolte, Sven Wach, Martin Hart, Sandra Sapich, Marc Wiesehöfer, Helge Taubert, Gunther Wennemuth, Norbert Eichner, Thomas Stempfl, Bernd Wullich, Gunter Meister, Friedrich A. Grässer

“…Surprisingly, overexpression of miR-24 induced focus formation and proliferation of DU145 cells, while miR-29b reduced proliferation. …”
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Discovery of MicroRNAs and Their Target Genes Related to Drought in Paulownia “Yuza 1” by High-Throughput Sequencing by Minjie Deng, Yabing Cao, Zhenli Zhao, Lu Yang, Yanfang Zhang, Yanpeng Dong, Guoqiang Fan

“…Furthermore, the expression levels of seven miRNAs (ptf-miR157b, ptf-miR159b, ptf-miR398a, ptf-miR9726a, ptf-M2153, ptf-M2218, and ptf-M24a) and their corresponding target genes were validated by quantitative real-time PCR. …”
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Macrophage to neuron communication via extracellular vesicles in neuropathic pain conditions by Francesca Picco, Lynda Zeboudj, Silvia Oggero, Vincenzo Prato, Thomas Burgoyne, Nikita Gamper, Marzia Malcangio

“…EV-mediated transfer of miR-155 suppresses phosphatase Ship1 expression and increases cytokine interleukin-6 (IL-6) contents. …”
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Improved Therapeutic Effect of Puerarin-Encapsulated PEG-PLGA Nanoparticle on an In Vitro Cerebral Infarction Model by Lei Li, Yan Li, Cheng Miao, Rui Liu

“…The BCEC/TF cell model was identified by immunofluorescence; the protein expression was detected by western blotting; the expression level of miR-424 in cells was measured by RT-qPCR; the targeting relationship between miR-424 and PDCD4 was confirmed by dual-luciferase reporter assay. …”
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Study on the Correlation between Interleukin-27 and CXCL10 in Pulmonary Tuberculosis by Jiahui Fan, Yefeng Yang, Liang Wang, Xiaoqian Shang, Li Zhang, Hu Sun, Yujie Ma, Ying Li, Jing Wang, Xiumin Ma

“…Key molecules such as has-let-7b-5p, has-miR-30a-3p, and has-miR-320b were screened out. …”
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Triptolide Inhibits Th17 Response by Upregulating microRNA-204-5p and Suppressing STAT3 Phosphorylation in Psoriasis by Qi He, Xingyue Wu, Quan Shi

“…Moreover, miR-204-5p directly targeted STAT3 in HaCaT cells. …”
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Magnetic Nanoparticle Based Nonviral MicroRNA Delivery into Freshly Isolated CD105+ hMSCs by Anna Schade, Paula Müller, Evgenya Delyagina, Natalia Voronina, Anna Skorska, Cornelia Lux, Gustav Steinhoff, Robert David

“…Therefore, we aimed to develop a nonviral miR carrier based on polyethylenimine (PEI) bound to magnetic nanoparticles (MNPs) for efficient miR delivery in freshly isolated hMSCs. …”
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Circulating miRNA-125b Is a Potential Biomarker Predicting Response to Rituximab in Rheumatoid Arthritis by Isabelle Duroux-Richard, Yves-Marie Pers, Sylvie Fabre, Meryem Ammari, Dominique Baeten, Guillaume Cartron, Isabelle Touitou, Christian Jorgensen, Florence Apparailly

“…Our results identify circulating miR-125b as a novel miRNA over expressed in RA and suggest that serum level of miR-125b is potential predictive biomarker of response to rituximab treatment.…”
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The MicroRNA-106a/20b Strongly Enhances the Antitumour Immune Responses of Dendritic Cells Pulsed with Glioma Stem Cells by Targeting STAT3 by Hui Zhou, Chengmei Sun, Cong Li, Shiting Hua, Feng Li, Ruichun Li, Dongpeng Cai, Yuxi Zou, Yingqian Cai, Xiaodan Jiang

“…We found that the levels of miR-106a/20b were downregulated, but the expression of STAT3 was significantly upregulated. …”
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