A Circulating miRNA-Based Scoring System Established by WGCNA to Predict Colon Cancer by Da Qin, Rui Wei, Si Liu, Shengtao Zhu, Shutian Zhang, Li Min

“…Among all these hub genes, hsa-miR-23a-3p (OR=2.6391, p=6.23×10‐5) and hsa-miR-663a (OR=1.4220, p=0.0069) were identified as an independent risk factor of colon cancer by multivariate regression. …”
Get full text

A Novel Type of Non-coding RNA, nc886, Implicated in Tumor Sensing and Suppression by Yong Sun Lee

“…nc886 (=vtRNA2-1, pre-miR-886, or CBL3) is a newly identified non-coding RNA (ncRNA) that represses the activity of protein kinase R (PKR). nc886 is transcribed by RNA polymerase III (Pol III) and is intriguingly the first case of a Pol III gene whose expression is silenced by CpG DNA hypermethylation in several types of cancer. …”
Get full text

Age Discrimination of Chinese Baijiu Based on Midinfrared Spectroscopy and Chemometrics by Shiqi Hu, Le Wang

“…In this paper, the raw and mellow Baijiu samples from different storage time are discriminated accurately throughout midinfrared (MIR) spectroscopy and chemometrics. Firstly, changing regularities of the substances in Chinese Baijiu are discussed by gas chromatography-mass spectrometry (GC-MS) during the aging process. …”
Get full text

Experimental Studies on the Changes in Resistivity and Its Anisotropy Using Electrical Resistivity Tomography by Tao Zhu, Jian-Guo Zhou, Jin-Qi Hao

“…Apparent resistivity data were acquired by MIR-2007 resistivity meter when samples were under uniaxial compression of servocontrol YAW-5000F loadingmachine in laboratory. …”
Get full text

Management at the enterprise on the basis of ESG principles in the conditions of sanctions pressure by S. A. Bannikov, A. P. Tsypin, P. G. Lakirev

Get full text

Neospora caninum infection specifically suppresses the expression of a host lncRNA XR_001919077.1 to facilitate parasite propagation by modulating host cell mitochondrial function... by Shan-Shan Zhao, De-Liang Tao, Jin-Ming Chen, Ming-Yi Zhang, Xin Yang, Jun-Ke Song, Qun Liu, Guang-Hui Zhao

“…Further study suggested that XR_001919077.1 acted as a sponge of Chi-miR-93-5p to promote the expression of sirt1, and the XR_001919077.1/Chi-miR-93-5p/sirt1 axis significantly delayed the in vitro growth of N. caninum in caprine EECs by regulating host cell mitochondrial function and autophagy. …”
Get full text

A Unique Case of Cardiac Arrest following K2 Abuse by Saif Ibrahim, Farah Al-Saffar, Thomas Wannenburg

“…To our knowledge, there are no previously documented cases of sudden cardiac death associated with synthetic cannabinoids although they have been linked to myocardial infarction in teenagers despite normal coronary angiography (Mir et al. (2011)).…”
Get full text

ncRNA-Mediated High Expression of LPCAT1 Correlates with Poor Prognosis and Tumor Immune Infiltration of Liver Hepatocellular Carcinoma by Qiu Sun, Xudong Liu, Qunlong Peng, Lei Hu, Xiaochun Jiang

“…SNHG3 was observed to be the most promising upstream lncRNA for the hsa-miR-139-5p/LPCAT1 axis in LIHC. In addition, the LPCAT1 level was significantly positively associated with tumor immune cell infiltration, biomarkers of immune cells, and immune checkpoint expression in LIHC. …”
Get full text

CircUCK2(2,3) promotes cancer progression and enhances synergistic cytotoxicity of lenvatinib with EGFR inhibitors via activating CNIH4–TGFα–EGFR signaling by Xindong Wei, Anfeng Si, Shuai Zhao, Yi Fu, Jilei Li, Kedeerya Aishanjiang, Yujie Ma, Chang Yu, Bo Yu, Chunhong Cui, Hui Wang, Xianming Kong, Shibo Li, Xiaoni Kong, Ying Tong, Hailong Wu

“…Conclusions CircUCK2(2,3) regulates a novel oncogenic pathway, miR-149-5p–CNIH4–TGFα–EGFR, in HCC, presenting a viable therapeutic target and biomarker for the precision treatment of HCC. …”
Get full text

Abnormal Expression of DICER1 Leads to Dysregulation of Inflammatory Effectors in Human Synoviocytes by Congshan Jiang, Jing Xu, Wenhua Zhu, Yongsong Cai, Si Wang, Yuanxu Guo, Ke Xu, Manman Geng, Nazim Hussain, Yan Han, Fujun Zhang, Qilan Ning, Liesu Meng, Shemin Lu

“…And then, gain or loss of miR-155 function could regulate the protein levels of MMP3 and MMP13. …”
Get full text

Computational identification of promising genetic markers associated with molecular mechanisms of reduced rice resistance to <i>Rhizoctonia solani</i> under excess nitrogen fertili... by E. A. Antropova, A. R. Volyanskaya, A. V. Adamovskaya, P. S. Demenkov, I. V. Yatsyk, T. V. Ivanisenko, Y. L. Orlov, Ch. Haoyu, M. Chen, V. A. Ivanisenko

“…Non-coding RNA analysis revealed 30 miRNAs targeting genes of the reconstructed gene network. For two miRNAs (Osa-miR396 and Osa-miR7695), about 7,400 unique long non-coding RNAs (lncRNAs) with various co-expression indices were found. …”
Get full text

“Spontaneous epidural hematoma in a pediatric patient following pansinusitis: a case report and review of the literature” by Shahin Nazarpour, Farid Qoorchi Moheb Seraj, Seyed Morteza Sharifzadeh Khavari, Mehran Seadghat, Mohammad Ali Abouei Mehrizi

Get full text

Comparison of Machine Learning Classification Methods for Determining the Geographical Origin of Raw Milk Using Vibrational Spectroscopy by Aimen El Orche, Amine Mamad, Omar Elhamdaoui, Amine Cheikh, Miloud El Karbane, Mustapha Bouatia

“…These findings demonstrate that FT-MIR spectroscopy, combined with machine learning methods, is an efficient and suitable approach to classify the geographical origins of raw milk.…”
Get full text

Evolving techniques in sentiment analysis: a comprehensive review by Mahander Kumar, Lal Khan, Hsien-Tsung Chang

Get full text

Fast Query-by-Singing/Humming System That Combines Linear Scaling and Quantized Dynamic Time Warping Algorithm by Gi Pyo Nam, Kang Ryoung Park

“…The experimental results with the 2009 MIR-QbSH corpus and the AFA MIDI 100 databases showed that the proposed method reduced the total searching time of reference data while obtaining the higher accuracy compared to the QDTW.…”
Get full text

GRAĐANSKI RAT KAO OBLIK UGROŽAVANJA KAPACITETA SISTEMA BEZBEDNOSTI DRŽAVE by Radoslav Gacinovic

“…Građanski ratovi se nikada ne završavaju kompromisom, tj. oni traju dok jedna od zaraćenih strana ne pobedi ili dok se silom od strane neke moćne države – država ili OUN silom nametne mir.…”
Get full text

Cannabidiol Modulates Neuroinflammatory and Estrogen-Related Pathways in a Sex-Specific Manner in a Chronic Stress Model of Depression by Uri Bright, Irit Akirav

“…In males, CBD restored the UCMS-induced downregulation of VS estrogen receptor genes ERα and ERβ. UCMS also altered miR-146a-5p expression, downregulating it in females (VS) and upregulating it in males (CA1), with no CBD effect. …”
Get full text

Unmasking The Hidden Clues: Shedding Light On The Potential Of Novel Biomarkers In Endometrial Cancer, Comparing RT-Qpcr And Immunohistochemical Analysis In Clinical Specimens by Sampana Fatima, Ayman Sabora, Iqra Anwar, Seher Naeem, Muhammad Abrar

“…Conclusions: RT-qPCR promises a highly sensitive and specific method for screening patients with endometrial carcinoma with expression of HE4, L1CAM, miR-200c, ARID1A, and PI3K. Keywords: Endometrial cancer, Immunohistochemical, biomarkers, radiotherapy. …”
Get full text

First Mid-infrared Detection and Modeling of a Flare from Sgr A* by Sebastiano D. von Fellenberg, Tamojeet Roychowdhury, Joseph M. Michail, Zach Sumners, Grace Sanger-Johnson, Giovanni G. Fazio, Daryl Haggard, Joseph L. Hora, Alexander Philippov, Bart Ripperda, Howard A. Smith, S. P. Willner, Gunther Witzel, Shuo Zhang, Eric E. Becklin, Geoffrey C. Bower, Sunil Chandra, Tuan Do, Macarena Garcia Marin, Mark A. Gurwell, Nicole M. Ford, Kazuhiro Hada, Sera Markoff, Mark R. Morris, Joey Neilsen, Nadeen B. Sabha, Braden Seefeldt-Gail

“…However, until now, sensitivity and angular resolution have been insufficient in the crucial mid-infrared (MIR) regime. The MIRI instrument on JWST has changed that, and we report the first MIR detection of Sgr A*. …”
Get full text

Open Soil Spectral Library (OSSL): Building reproducible soil calibration models through open development and community engagement. by José L Safanelli, Tomislav Hengl, Leandro L Parente, Robert Minarik, Dellena E Bloom, Katherine Todd-Brown, Asa Gholizadeh, Wanderson de Sousa Mendes, Jonathan Sanderman

“…The results of 10-fold cross-validation with refitting show that, in general, mid-infrared (MIR)-based models are significantly more accurate than visible and near-infrared (VisNIR) or near-infrared (NIR) models. …”
Get full text