原发性肝癌术后早期复发密切相关microRNA的筛选及应用 by 区应亮, 侯宝华, 简志祥

“…mir-451?mir-486-5p?mir-602?mir-551b?mir-96?mir-502-3p与原发性肝癌术后早期复发密切相关?…”
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Managing cardiovascular events, hyperglycemia, and obesity in type 2 diabetes through microRNA regulation linked to glucagon-like peptide-1 receptor agonists by Xiaolei Miao, Maryam Davoudi, Zahra Alitotonchi, Ensieh Sadat Ahmadi, Fatemeh Amraee, Ashraf Alemi, Reza Afrisham

“…Results GLP-1RAs modify the expression of miRNAs involved in endothelial function, sugar metabolism, and adipogenesis, including but not limited to miR-27b, miR-130a, and miR-210. Baseline miR-15a-5p predict weight loss, while higher miR-378-3p and miR-126-3p levels are related to better glycemic control and lower HbA1c and FPG at one year post-treatment. miR-375-5p was also reported as a predictor of HbA1c levels. …”
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MicroRNA-147a Targets SLC40A1 to Induce Ferroptosis in Human Glioblastoma by Peng Xu, Fei-Hang Ge, Wen-Xin Li, Zhen Xu, Xue-Li Wang, Jing-Lan Shen, Ai-Bo Xu, Rong-Rong Hao

“…This study aims to determine the involvement of microRNA (miR)-147a in regulating ferroptosis of glioblastoma in vitro. …”
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Left ventricle function and post-transcriptional events with exercise training in pigs. by Stephanie L Samani, Shayne C Barlow, Lisa A Freeburg, Traci L Jones, Marlee Poole, Mark A Sarzynski, Michael R Zile, Tarek Shazly, Francis G Spinale

“…LV KC fell by approximately 50% and rKm by 30% following exercise (both p < 0.05). Using an 84 miR array, 34 (40%) miRs changed with exercise, whereby 8 of the changed miRs (miR-19a, miR-22, miR-30e, miR-99a, miR-142, miR-144, miR-199a, and miR-497) were correlated to the change in KC (r ≥ 0.5 p < 0.05) and mapped to matrix and calcium handling processes. …”
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Association of functional variants in miRNA genes with the risk of coronary heart disease by Taqweem Ul Haq, Muhammad Riaz Khan, Sajjad Ali, Tariq Aziz, Thamer H. Albekairi, Aftab Ali Shah

“…In this study, we investigated the associations of miRNA genes MIR222, MIR423, MIR4274, and MIR3117 with the pathogenesis of CHD. …”
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MicroRNA-101-3p Suppresses mTOR and Causes Mitochondrial Fragmentation and Cell Degeneration in COPD by Lei Fang, Xinggang Wang, Ming Zhang, Petra Khan, Michael Tamm, Michael Roth

“…It also modifies mTOR activity, microRNA (miR)-101-3p expression, and mitochondria function. …”
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Diagnostic Test to Identify Parkinson’s Disease from the Blood Sera of Chinese Population: A Cross-Sectional Study by Guangan Tong, Pingping Zhang, Wenbin Hu, Kun Zhang, Xianwen Chen

“…Five common miRNAs viz. miR-151a-5p, miR-24, mir-485-5p, mir-331-5p, and mir-214 were found to be upregulated with statistical significance in both the serum exosome and CSF exosomes. …”
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Pilot study on the impact of HIFU treatment on miRNA profiles in vaginal secretions of uterine fibroids and adenomyosis patients by Wei-Chun Chen, Ting-Chang Chang, Lynn Perera, Mei-Hsiu Cheng, Jun-Jie Hong, Chao-Min Cheng

“…Notably, hsa-miR-7977, hsa-miR-155-5p, hsa-miR-191-5p, and hsa-miR-223-3p showed significant changes in fibroid cases, except in low-energy treatments. hsa-miR-7977 consistently decreased post-treatment, while hsa-miR-155-5p decreased in the least efficient cases. …”
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MicroRNA-21-5p Reduces Hypoxia/Reoxygenation-Induced Neuronal Cell Damage through Negative Regulation of CPEB3 by Bin Wang, Ping Yu, Wei Lin, Zhaohui Zhai

“…To explore the role of microRNA-21-5p (miR-21-5p) in hypoxia/reoxygenation- (H/R-) induced HT22 cell damage. …”
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Clinical Role of Epigenetics and Network Analysis in Eye Diseases: A Translational Science Review by Michele Lanza, Giuditta Benincasa, Dario Costa, Claudio Napoli

“…A large panel of upregulated micro-RNAs (miRNAs), including hsa-hsa-miR-494, hsa-let-7e, hsa-miR-513-1, hsa-miR-513-2, hsa-miR-518c, hsa-miR-129-1, hsa-miR-129-2, hsa-miR-198, hsa-miR-492, hsa-miR-498, hsa-miR-320, hsa-miR-503, and hsa-miR-373,∗ may have a putative role in the development of retinoblastoma. …”
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调控microRNA-99b表达对宫颈癌SiHa细胞增殖和凋亡的作用

“…[目的] 探讨上调microRNA-99b(miR-99b)表达对宫颈癌SiHa细胞增殖和凋亡的作用及可能的机制。[方法] 宫颈癌SiHa细胞分正常对照组、阴性对照组和miR-99b调控组。…”
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MicroRNA Regulation for Inflammasomes in High Glucose-Treated ARPE-19 Cells by Ji Hong Kim, Hyoseon Yu, Ji Hye Kang, Eun Hee Hong, Min Ho Kang, Mincheol Seong, Heeyoon Cho, Yong Un Shin

“…The expression levels of five miRNAs (miR-185, miR-17, miR-20a, miR-15a, and miR-15b) were measured in high glucose-treated ARPE-19 cells using real-time quantitative polymerase chain reaction. …”
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MicroRNA-155: Regulation of Immune Cells in Sepsis by Ming Chen, Fuquan Wang, Haifa Xia, Shanglong Yao

“…MicroRNAs are small noncoding RNAs which regulate gene expression at the posttranscriptional level. miR-155 is encoded by the miR-155 host gene (miR155HG), also known as the noncoding B cell integration cluster (BIC). …”
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Profil Ekspresi MikroRNA Kanker Payudara di Purwokerto by Ari Dwi Nurasih, Indah Sulistiyawati, Muhammad Falah

“…Hasil:  Biomarker kanker payudara di Purwokerto adalah MikroRNA yang mengalami upregulation adalah hsa-miR-543 (sebanyak 1612,28 kali), hsa-miR-495-3p (1797,95 kali), hsa-miR-382-5p (8780,32 kali), hsa-miR-155-5p (8552,18 kali) dan hsa-miR-154-5p (2339,41 kali). mikroRNA yang mengalami downregulation adalah hsa-miR-590-5p (sebanyak 4,70 kali), hsa-miR-33a-5p (sebanyak 74,29 kali), hsa-miR-100-5p (sebanyak 23,09 kali), hsa-miR-19b-3p (sebanyak 11,71 kali) dan hsa-miR-144-3p (sebanyak 25,30 kali) (p < 0,05). …”
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Identification of urothelial cancer-associated 1 (UCA1) as a diagnostic biomarker of pre-eclampsia via regulating microRNA-16 and its downstream signaling pathway by Ye-Hong Xv, Wei Gao, Liao-Jv Wang

“…Introduction In this study, we investigated the clinical value of using urothelial cancer-associated 1 (UCA1) and microRNA-16 (miR-16) as biomarkers for the diagnosis of pre-eclampsia (PE). …”
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Propofol Ameliorates Microglia Activation by Targeting MicroRNA-221/222-IRF2 Axis by Xi Xiao, Yuanyuan Hou, Wei Yu, Sihua Qi

“…Gain- and loss-of-function studies revealed that miR-221 and miR-222 were profoundly implicated in microglia activation. …”
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MicroRNA and Putative Target Discoveries in Chrysanthemum Polyploidy Breeding by Fengjiao Zhang, Jingya Zhao, Sujuan Xu, Weimin Fang, Fadi Chen, Nianjun Teng

“…As a result, a total of 170 miRNAs were identified and there are 41 special miRNAs in cross of paternal chromosome doubling, such as miR169b, miR440, and miR528-5p. miR164c and miR159a were highly expressed in a normal embryo at 18 days after pollination, suggesting the regulatory role at the late stage of embryonic development. miR172c was only detected in the normal embryo at 18 days after pollination, which means that miR172c mainly mediates gene expression in postembryonic development and these genes may promote embryo maturation. …”
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MicroRNA-4735-3p Facilitates Ferroptosis in Clear Cell Renal Cell Carcinoma by Targeting SLC40A1 by Cairong Zhu, Zhiquan Song, Zhen Chen, Tianqi Lin, Haili Lin, Zhenqiang Xu, Fen Ai, Shijiao Zheng

“…The present study was aimed at investigating the role and underlying mechanisms of microRNA-4735-3p (miR-4735-3p) in ccRCC. Methods. Human ccRCC cell lines were transfected with the miR-4735-3p mimic or inhibitor to manipulate the expression of miR-4735-3p. …”
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LOC389023 在难治性颞叶癫痫中分子海绵机制的预测 by 温跃桃, 姜维, 吴昆仑, 石全红

“…【结果】免疫组织化学染色和western blot 分析结果显示，DPP10 在癫痫组中高表达（P < 0.05）， Kv4.3 则低表达（P < 0.05）；DPP10 与Kv4.3 共表达于神经元的细胞膜且两者有相互作用；通过软件预测得到5 个候选 microRNA（miR-32-5p，miR-140-5p，miR-367-3p，miR-25-3p和miR-4325）；qPCR检测结果显示：在癫痫组中，LOC389023 和miR-140-5p表达水平均低于对照组（P＜0.05），miR-25-3p和miR-367-3p表达水平均高于对照组（P < 0.05），而miR-32-5p 和miR-4325无明显变化（P > 0.05）。…”
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MicroRNA-150-3p enhances the antitumour effects of CGP57380 and is associated with a favourable prognosis in non-small cell lung cancer by Hongmei Zheng, Songqing Fan, Jiadi Luo, Qiuyuan Wen, Hongjing Zang

“…These results were validated in the TCGA and revealed that miR-150-3p was expressed at low levels in NSCLC tissues (P < 0.0001) and that patients with high miR-150-3p expression had a better prognosis (P = 0.042). …”
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