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761
Socioeconomic indicators related to the global burden of breast cancer in women in 2020: an analysis of WHO data
Published 2024-11-01“…The breast cancer mortality to incidence ratio (MIR), a quantitative indicator of the burden of breast cancer, was calculated. …”
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762
The Kat in the HAT: The Histone Acetyl Transferase Kat6b (MYST4) Is Downregulated in Murine Macrophages in Response to LPS
Published 2018-01-01“…This is despite the observation that miR-487b, a putative regulator of Kat6B expression, is mildly stimulated by LPS, but strongly suppressed by LPS/NECA. …”
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763
Improvement in Analytical Methods for Determination of Sugars in Fermented Alcoholic Beverages
Published 2018-01-01“…The MIR-PLS method was found to give good prediction of individual sugars: glucose, fructose, sucrose, and maltose in the alcoholic beverages with less than 4% error. …”
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764
Senescence-related circRNA circHIF-1α is associated with pancreatic cancer progression
Published 2025-01-01“…Mechanistically, circHIF-1α inhibited senescence and accelerated the progression of PC cells through miR-375 sponging, thereby promoting HIF-1α expression levels. …”
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765
MicroRNA as a Potential Diagnostic and Prognostic Biomarker in Diffuse Large B‐Cell Lymphoma: A Systematic Review and Meta‐Analysis
Published 2025-01-01“…The pooled OS and PFS HRs (< 1) were 0.4965 (95% CI: 0.3576–0.6894, p < 0.0001) and 2.4883 (95% CI: 1.7367–3.5650, p < 0.0001). MiR‐155 diagnostic values had a sensitivity of 0.710 (p > 0.1) and a specificity of 0.725 (p < 0.05), with an AUC of 0.776. miR‐21 diagnostic values had an AUC of 0.8468 (p < 0.0001) and OS HR of 2.8938. …”
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766
KLF12 Aggravates Angiotensin II‐Induced Cardiac Remodeling in Male Mice by Transcriptionally Inhibiting SMAD7
Published 2025-02-01“…Hence, we generated adult mice with cardiac fibroblast‐specific overexpression of KLF12 using lentivirus or miRNA (miR‐1/133TS) technology. Compared with control mice, KLF12‐miR1/133TS transfected mice exhibited exacerbated cardiac remodeling and function. …”
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767
Synaptotagmin-1 attenuates myocardial programmed necrosis and ischemia/reperfusion injury through the mitochondrial pathway
Published 2025-01-01“…We further found that Syt1 expression was negatively regulated by miR-193b-3p. MiR-193b-3p regulated cardiomyocyte necrosis and mPTP opening by targeting Syt1. …”
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768
HIF-1α and VEGF Immunophenotypes as Potential Biomarkers in the Prognosis and Evaluation of Treatment Efficacy of Atherosclerosis: A Systematic Review of the Literature
Published 2025-01-01“…Increased HIF-1α in vascular smooth muscle cells, macrophages, or endothelial cells, under hypoxia, chronic loss of nitric oxide (NO), or reduced micro ribonucleic acid (miRNA)-17 and miR-20, is associated with the upregulation of pro-inflammatory molecules, such as interleukin-1 beta (IL-1β) or tumor necrosis factor-alpha (TNF-α), increased migration inhibitory factor of macrophages, glycolytic flux, lipid accumulation, necroptosis via miR-383, and adverse effects in atherosclerosis and plaque vulnerability. …”
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769
A comparative analysis of global and Chinese trends in the burden of kidney cancer from 1990 to 2021
Published 2025-02-01“…Additionally, the age-standardized rate of kidney cancer in males was notably higher than in females, particularly among middle-aged males. The (1-MIR) of renal cancer increased from 0.36 to 0.62 in China and from 0.49 to 0.58 globally. …”
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770
An Integrating Approach for Genome-Wide Screening of MicroRNA Polymorphisms Mediated Drug Response Alterations
Published 2017-01-01“…We developed a user-friendly online database of this approach named Mir2Drug.…”
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771
Predicting the Progress of Tuberculosis by Inflammatory Response-Related Genes Based on Multiple Machine Learning Comprehensive Analysis
Published 2023-01-01“…The results of the miRNA–genes network analysis suggested a potential role of hsa-miR-3163 in the molecular mechanism of LTBI progressing into ATB. …”
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772
Comparative analysis of the whole transcriptome landscapes of muscle and adipose tissue in Qinchuan beef cattle
Published 2025-01-01“…Among them, 55 ceRNA axes were involved, including circRNA12990 - bta-miR-133a_L-1R + 1 - MYO6/ZEB2, circRNA2893/MSTRG.28538.1/MSTRG.11613.4 - pma-miR-145-5p_R + 2 - EYA4 and MSTRG.26982.1 - bta-let-7e_R + 1 - RBM40. …”
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773
To Develop Biomarkers for Diabetic Nephropathy Based on Genes Related to Fibrosis and Propionate Metabolism and Their Functional Validation
Published 2024-01-01“…Moreover, 8 TFs, 60 miRNAs, and 7 mRNAs formed the TF–miRNA–mRNA regulatory network, including USF1-hsa-mir-1296-5p-AGT and HIF1A-hsa-mir-449a-5p-ACE2. …”
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774
Efficacy of Shenqi Pollen Capsules for High-Altitude Deacclimatization Syndrome via Suppression of the Reoxygenation Injury and Inflammatory Response
Published 2019-01-01“…SPC therapy also reduced the serum levels of CK, CK-MB, LDH, IL-17A, TNF-α, and miR-155 and elevated IL-10 and miR-21 levels. We thus demonstrate that SPCs effectively ameliorated HADAS symptoms in these subjects via suppression of the hypoxia-reoxygenation injury and inflammatory response.…”
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775
Circulating MicroRNAs in Patients with Psoriasis Treated with Anti-IL-23: A Cohort Study
Published 2025-01-01“…Conclusions This study identifies specific circulating miRNAs, including miR-200a-3p, as potential biomarkers for monitoring treatment responses in psoriasis patients. …”
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776
Identifying a Serum Exosomal-Associated lncRNA/circRNA-miRNA-mRNA Network in Coronary Heart Disease
Published 2021-01-01“…The LncRNA/circRNA-miRNA-mRNA interaction axes (RPL7AP11/hsa-miR-17-5p/UBC and RPL7AP11/hsa-miR-20b-5p/UBC) were obtained from the network. …”
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777
TET1 is a Tumor Suppressor That Inhibits Papillary Thyroid Carcinoma Cell Migration and Invasion
Published 2020-01-01“…The knockdown of the TET1 gene promoted cell migration and invasion in BCPAP cells. The expression of miR-7, miR-15/16 cluster, and let-7 family was downregulated, while the expression of let-7e was upregulated after siRNA-TET1 treatment in BCPAP cells. …”
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778
New bitongling regulates gut microbiota to predict angiogenesis in rheumatoid arthritis via the gut-joint axis: a deep neural network approach
Published 2025-02-01“…Additionally, NBTL upregulated miR-20a-5p and miR-223-3p, contributing to its anti-angiogenic effects.ConclusionNBTL exhibits significant therapeutic potential in RA by modulating gut microbiota and inhibiting the VEGF signaling pathway. …”
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779
MEL-IRIS: An Online Tool for Audio Analysis and Music Indexing
Published 2009-01-01“…Especially in Music Information Retrieval (MIR), the visualization of the chromatic analysis can be used for comparison, pattern recognition, melodic sequence prediction, and color-based searching. …”
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780
The anti-cancerous mechanism of licochalcone A on human hepatoma cell HepG2 based on the miRNA omics
Published 2023-07-01“…Afterwards, the miRNA-target networks were established to screen key dysregulated miRNAs. Two key miRNAs (hsa-miR-133b and hsa-miR-145-5p) were filtered. Finally, the miRNA-target-transcription factor networks were constructed for these key miRNAs. …”
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