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Huntington Disease Health Related Quality of Life, Function and Well Being: The Patient’s Perspective
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Formal guidelines from an expert panel: intensive care unit medical staffing, organisation and working hours to improve quality of life at work in France
Published 2025-01-01“…The French Intensive Care Society (FICS) and the French National Council of Intensive Care Medicine (CNP MIR, Conseil National Professionel de Médecine Intensive Réanimation) have established a technical committee of experts, the purposes of which were to draft recommendations regarding staffing needs in ICUs and to propose optimal organisation of work hours, a key objective being improved workplace quality of life. …”
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Carotid Artery Stenting Outcomes by Neurointerventional Surgeons (CASONI)
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NL-Augmenter: A Framework for Task-Sensitive Natural Language Augmentation
Published 2023-04-01Get full text
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miRNA-21和miRNA-134在乳腺癌患者血清中表达情况及其临床意义
Published 2016-01-01“…[方法] 收集47例乳腺癌及50例正常体检人群血清,通过实时荧光定量PCR(RT-PCR)检测各组miR-630、miR-21、miR-195、miR-134 、miR-200a、miR-381、miR-1228的表达情况。…”
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The Role of Autophagy and Related MicroRNAs in Inflammatory Bowel Disease
Published 2018-01-01“…Related studies have shown that miR-142-3p, miR-320, miR-192, and miR-122 target NOD2, an IBD-relevant autophagy gene, to modulate autophagy in IBD. miR-142-3p, miR-93, miR-106B, miR-30C, miR-130a, miR-346, and miR-20a regulate autophagy by targeting ATG16L1 through several different pathways. miR-196 can downregulate IRGM and suppress autophagy by inhibiting the accumulation of LC3II. …”
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miRNA表达谱改变与儿童急性淋巴细胞白血病复发的相关性
Published 2014-01-01“…【方法】 采用基因芯片技术检测10例初发-缓解配对的ALL患儿骨髓细胞的miRNA表达谱(基因芯片组),定量RT-PCR(qRT-PCR)方法验证异常miRNA在ALL患儿骨髓细胞内的表达(qRT-PCR组),结合患儿临床资料分析异常表达的miRNA与ALL预后的关系?【结果】 基因芯片结果显示:初发患儿miR-708?miR-181b?miR-199a-3p?miR-320a和miR-145表达上调最为明显,而miR-223?…”
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MicroRNA Expression in Cutaneous Lupus: A New Window to Understand Its Pathogenesis
Published 2019-01-01“…HD. miR-150, miR-1246, and miR-21 levels were downregulated in DLE vs. …”
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Circulating miRNAs as Biomarkers for Prostate Cancer Diagnosis in Subjects with Benign Prostatic Hyperplasia
Published 2020-01-01“…RT-qPCR was used to quantify the levels of 10 miRNAs, which included miR-18a, miR-34a, miR-106b, miR-183, miR-200a, miR-301a, miR-141, miR-182, miR-200b, and miR-375 in serum. …”
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Aberrant Expression of MicroRNA-15a and MicroRNA-16 Synergistically Associates with Tumor Progression and Prognosis in Patients with Colorectal Cancer
Published 2014-01-01“…The aim of this study was to reveal the associations of microRNA miR-15a and miR-16 dysregulation with clinicopathological characteristics and prognosis in patients with colorectal cancer. …”
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鼻咽癌差异表达miRNAs筛选研究
Published 2007-01-01“…运用靶基因预测软件并结合全基因组表达谱芯片结果预测差异表达miRNAs可能调控的靶基因,并利用westernblot技术检测预测的靶基因在原代培养的鼻咽癌细胞中的表达。【结果】miRNAs芯片结果显示,鼻咽癌中miR-203、miR-503、miR-424、miR-141和miR-148a表达下调,而miR-25、miR-195和miR-15a表达上调,其差异表达均在2倍以上;荧光定量RTPCR结果与miRNAs芯片的结果较符合;其中miR-203的预测靶基因为CCNG1和SPARC,Western blot结果显示,其在原代培养的鼻咽癌细胞亦高表达。…”
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The Effects of MicroRNAs on Cardiomyopathy in a Rat Model of Streptozotocin-induced Diabetes Mellitus
Published 2025-01-01“…Methods: Therefore, miRNAs obtained from rat heart tissue were analyzed by microarray, and twelve miRNAs (rno-miR-200c-3p, rno-miR-129-5p, rno-miR-150-3p, rno-miR-3584-5p, rno-miR-34c-3p, rno-miR-342-3p, rno-miR-466b-3p, rno-miR-466c-3p, rno-miR-31a-3p, rno-miR-15b-5p, rno-miR-196b-3p, and rno-miR-208a-5p) with changed expression levels were validated by real-time polymerase chain reaction analysis. …”
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Six MicroRNA Prognostic Models for Overall Survival of Lung Adenocarcinoma
Published 2022-01-01“…The prognostic models of six miRNA genes were obtained: miR-195-3p, miR-5571-5p, miR-584-3p, miR-494-3p, miR-4664-3p, and miR-1293. …”
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儿童急性白血病耐药相关microRNA的筛选
Published 2012-01-01“…治疗后骨髓完全缓解及早期复发的儿童急性白血病的骨髓样本,提取RNA检测筛查的白血病细胞耐药相关的microRNA的表达,进一步验证体外实验的结果?【结果】 ①在K562/DOX耐药细胞株,miR-20a?miR-188-3p?miR-214等microRNA表达上调,而miR-331-5p?…”
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