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721
Reconstruction and computational analysis of the microRNA regulation gene network in wheat drought response mechanisms
Published 2025-01-01“…These proteins are associated with phytohormone signaling pathways and calcium-dependent protein kinases significant in plant water deficit adaptation. Several miRNAs (MIR7757, MIR9653a, MIR9671 and MIR9672b) were identified that had not been previously discussed in wheat drought adaptation. …”
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722
LANCL1 as the Key Immune Marker in Neuropathic Pain
Published 2022-01-01“…In this study, we found that LANCL1 may be a protective factor for NeuP, and the miR-6325/LANCL1 axis may be involved in the occurrence and development of NeuP. …”
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723
The Potential of MicroRNAs as Novel Biomarkers for Transplant Rejection
Published 2017-01-01“…The control of gene expression by microRNAs (miRNAs, miR) influences many cellular functions, including cellular differentiation, cell proliferation, cell development, and functional regulation of the immune system. …”
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724
Polarization conversion in soft glass fluoride and chalcogenide fibers for mid-infrared applications
Published 2025-01-01“…Mid-infrared (MIR) technologies are crucial for applications from chemical sensing to precision medical surgery. …”
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725
Construction and Investigation of MicroRNA-mRNA Regulatory Network of Gastric Cancer with Helicobacter pylori Infection
Published 2020-01-01“…Patients with higher expression of hsa-miR-196b-3p, CALML4, or SMAD6 or lower expression of PITX2 or TGFB2 had better outcomes than those with lower expression of hsa-miR-196b-3p, CALML4, or SMAD6 or higher expression of PITX2 or TGFB2 (P<0.05). …”
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726
Impact of 17-alpha ethinyl estradiol (EE2) and diethyl phthalate (DEP) exposure on microRNAs expression and their target genes in differentiated SH-SY5Y cells
Published 2025-01-01“…Our results show that both EDCs downregulated specific miRNAs—miR-18b-5p, miR-200a-3p, and miR-653-5p—affecting key processes such as cell proliferation, survival, and apoptosis. …”
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727
Integrated analysis of transcriptome, sRNAome, and degradome involved in the drought-response of maize Zhengdan958
Published 2025-01-01“…Tissue-specific expression profile and regulatory network analysis revealed that miR528a/b-Zm00001d021850, miR408a/b-Zm00001d020794, and miR164e-Zm00001d003414 might be essential in root-specific drought stress response of maize Zhengdan958 seedlings. …”
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728
Role of B7H4 and Fas in regulation of trophoblast cells and development of pre-eclampsia: a cross-sectional study
Published 2025-12-01“…Overexpression of B7H4 alleviated the inhibitory effects of miR-4319, which were reversed by Fas knockdown (p < 0.05).Conclusions miR-4319 mediates the progression of trophoblast progression by negatively regulating the expression of B7H4 and Fas. …”
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729
Urinary Proteome and Exosome Analysis Protocol for the Discovery of Respiratory Diseases Biomarkers
Published 2025-01-01“…We could confirm the expression of miRNAs previously connected to respiratory diseases (i.e., miR-16-5p, miR-21-5p, miR-146a-5p, and miR-215-5p) in urine exosomes by RTqPCR. …”
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730
Inhibition of Glycogen Synthase Kinase and the Neuroprotective Function of Conjugated ZnO-Osthol Nanoparticles in Alzheimer’s Disease
Published 2022-01-01“…The key reason was that by upregulating miR-132, osthol could inhibit APP expression to prevent AD from occurring.…”
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731
hsa_circWDR37_016 Regulates Hypoxia-Induced Proliferation of Pulmonary Arterial Smooth Muscle Cells
Published 2022-01-01“…Furthermore, bioinformatics and Luciferase assay showed that circWDR37 directly sponged hsa-miR-138-5p (miR-138) and was involved in the immunoregulatory and inflammatory processes of PAH. …”
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732
Inferring single-cell and spatial microRNA activity from transcriptomics data
Published 2025-01-01“…We also show miR-519a-3p differential activity in specific cell populations.…”
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733
Liver Expression of Sulphotransferase 2A1 Enzyme Is Impaired in Patients with Primary Sclerosing Cholangitis: Lack of the Response to Enhanced Expression of PXR
Published 2015-01-01“…Transcription of SULT2A1 gene is induced by pregnane-X-receptor (PXR) and can be repressed by miR-378a-5p. We studied the PXR/SULT2A1 axis in chronic cholestatic conditions: primary sclerosing cholangitis (PSC) and primary biliary cirrhosis (PBC). …”
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734
Identification of HOXA9 methylation as an epigenetic biomarker predicting prognosis and guiding treatment choice in acute myeloid leukemia
Published 2025-02-01“…Bioinformatics analysis demonstrated the association of HOXA9 expression with diverse leukemia-related genes (HOXAs, SOSTDC1, MEG3, miR-10a, miR-381 and miR-193b) and signaling pathways (PI3K-Akt signaling) in AML. …”
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735
Transcriptome, miRNA, and degradome sequencing reveal the leaf stripe (Pyrenophora graminea) resistance genes in Tibetan hulless barley
Published 2025-01-01“…Using RNA-seq, small RNA sequencing (miRNA-seq) combined with degradome sequencing (degradome-seq), four pairs associated with leaf-stripe miRNAs and target genes were obtained, namely Hvu-miR168-5p and Argonaute1 (HvAGO1), Hvu-novel-52 and growth-regulating factor 6 (HvGRF6), Hvu-miR6195 and chemocyanin-like protein (CLP), and Hvu-miR159b and gibberellin-dependent MYB (GAMYB). …”
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736
miRNAs in Extracellular Vesicles from iPS-Derived Cardiac Progenitor Cells Effectively Reduce Fibrosis and Promote Angiogenesis in Infarcted Heart
Published 2019-01-01“…Amongst the highly enriched miRNAs, miR-373 was strongly antifibrotic, targeting 2 key fibrogenic genes, GDF-11 and ROCK-2. miR-373 mimic itself was highly efficacious in preventing scar formation in the infarcted myocardium. …”
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737
Associations between milk infrared-predicted plasma biomarkers of stress resilience and fertility in dairy cattle: Insights for enhancing breeding programs and herd management
Published 2025-02-01“…The 2 databases were merged according to the milk test day (and thus, the MIR spectrum) closest to the date of insemination. …”
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738
Comecon as the «Core» of Alternative Globalization
Published 2021-06-01“…Book review: «The World System of Socialism» and the Global Economy in the mid-1950s – mid-1970s/ ed. by M.A. Lipkin. Moscow: Ves’ mir, 2019.…”
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739
Diagnostic Role of Plasma MicroRNA-21 in Stable and Unstable Angina Patients and Association with Aging
Published 2020-01-01“…Total RNA was extracted from plasma by using miRNA-based TRIzol reagent. Plasma miR-21 expression levels were determined by real-time polymerase chain reaction. …”
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740
Geographical origin discrimination of Chenpi using machine learning and enhanced mid-level data fusion
Published 2025-02-01“…Thirty-nine samples from eight regions in Xinhui district (Guangdong, China) are analyzed by gas chromatography (GC) and mid-infrared (MIR) technique. Four machine learning methods are employed to establish discrimination models based on GC and MIR data, with two mid-level data fusion strategies to combine the data. …”
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