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661
Discovery of MicroRNAs and Their Target Genes Related to Drought in Paulownia “Yuza 1” by High-Throughput Sequencing
Published 2017-01-01“…Furthermore, the expression levels of seven miRNAs (ptf-miR157b, ptf-miR159b, ptf-miR398a, ptf-miR9726a, ptf-M2153, ptf-M2218, and ptf-M24a) and their corresponding target genes were validated by quantitative real-time PCR. …”
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662
Improved Therapeutic Effect of Puerarin-Encapsulated PEG-PLGA Nanoparticle on an In Vitro Cerebral Infarction Model
Published 2020-01-01“…The BCEC/TF cell model was identified by immunofluorescence; the protein expression was detected by western blotting; the expression level of miR-424 in cells was measured by RT-qPCR; the targeting relationship between miR-424 and PDCD4 was confirmed by dual-luciferase reporter assay. …”
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663
Study on the Correlation between Interleukin-27 and CXCL10 in Pulmonary Tuberculosis
Published 2022-01-01“…Key molecules such as has-let-7b-5p, has-miR-30a-3p, and has-miR-320b were screened out. …”
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664
Triptolide Inhibits Th17 Response by Upregulating microRNA-204-5p and Suppressing STAT3 Phosphorylation in Psoriasis
Published 2022-01-01“…Moreover, miR-204-5p directly targeted STAT3 in HaCaT cells. …”
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665
Magnetic Nanoparticle Based Nonviral MicroRNA Delivery into Freshly Isolated CD105+ hMSCs
Published 2014-01-01“…Therefore, we aimed to develop a nonviral miR carrier based on polyethylenimine (PEI) bound to magnetic nanoparticles (MNPs) for efficient miR delivery in freshly isolated hMSCs. …”
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666
Circulating miRNA-125b Is a Potential Biomarker Predicting Response to Rituximab in Rheumatoid Arthritis
Published 2014-01-01“…Our results identify circulating miR-125b as a novel miRNA over expressed in RA and suggest that serum level of miR-125b is potential predictive biomarker of response to rituximab treatment.…”
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667
The MicroRNA-106a/20b Strongly Enhances the Antitumour Immune Responses of Dendritic Cells Pulsed with Glioma Stem Cells by Targeting STAT3
Published 2022-01-01“…We found that the levels of miR-106a/20b were downregulated, but the expression of STAT3 was significantly upregulated. …”
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668
Total Glucosides of Paeony Alleviate Cell Apoptosis and Inflammation by Targeting the Long Noncoding RNA XIST/MicroRNA-124-3p/ITGB1 Axis in Renal Ischemia/Reperfusion Injury
Published 2020-01-01“…Moreover, XIST was competitively bound to miR-124-3p, and ITGB1 was a target of miR-124-3p. miR-124-3p overexpression or ITGB1 inhibition rescued the reduction effect on viability and mitigated the promoting effects on cell apoptosis and inflammation caused by XIST overexpression in H/R-treated renal cells. …”
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669
Improved Predictability of Diagnosis and Prognosis Using Serum‐ and Tissue‐Derived Extracellular Vesicles From Bulk mRNA Sequencing in Pancreatic Ductal Adenocarcinoma
Published 2025-01-01“…Results The combination of miR142‐3p, miR148a‐3p, and CA199 showed a higher AUC (0.747) compared to CA199 alone (0.716) in ROC curve analysis. …”
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670
RETRACTED: Long non‐coding RNA Sox2OT promotes coronary microembolization‐induced myocardial injury by mediating pyroptosis
Published 2022-06-01“…In addition, miR‐23b overexpression could supplement the cytosolic miR‐23b reserves to target TLR‐4 and partially reverse Sox2OT‐mediated pyroptosis in LPS‐treated H9C2 cells. …”
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671
Different expression of circulating microRNA profile in tibetan OSAHS with metabolic syndrome patients
Published 2025-01-01“…We identified IKBKB, PIK3R1, and MAP2K1 as the target genes most associated with Mets pathogenesis in OSAHS, regulated by miR-503-5p, miR-497-5p, and miR-497-5p, respectively. …”
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672
Genome-Wide Expression of MicroRNAs Is Regulated by DNA Methylation in Hepatocarcinogenesis
Published 2015-01-01“…These data suggest that the expressions of miR-125b and miR-199a are dramatically regulated by DNA hypermethylation that plays a key role in hepatocarcinogenesis.…”
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673
Regulation of UCP1 in the Browning of Epididymal Adipose Tissue by β3-Adrenergic Agonist: A Role for MicroRNAs
Published 2014-01-01“…Furthermore, potential UCP1-targeting miR-9 and miR-338-3p in epididymal adipose tissue were significantly decreased in CL316243 group. …”
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674
Analyzing the cancer mortality-to-incidence ratios and health expenditures in the aging population: a 20-year comparative study across high-income countries
Published 2025-01-01“…A generalized linear model was employed to examine the association between MIR, and health expenditures and health development index score.ResultsIncluded countries showed a statistically significant negative association between MIR and both HE, and HE, indicating that higher HDI and HE are associated with decreased MIR with the highest decrease was for China, the coefficient for HDI is −1.29 (95% CI: –1.35 to −1.24, p < 0.0001), the coefficient for HE is −0.103 (95% CI: –0.17 to −0.03, p < 0.0001). …”
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675
Computational identification and experimental validation of novel Saccharum officinarum microRNAs along with their targets through RT-PCR approach
Published 2025-12-01“…Similarly, the sof-miR7768b and sof-miR6249b monitor the pathogenesis-related protein and zinc finger, C2H2 type protein, which assist as transcription factors. …”
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676
Tissue-specific effects of benzo[a]pyrene and DDT on microRNA expression profile in female rats
Published 2018-04-01“…Using in silico methods, an analysis of the rat genome was carried out to find microRNAs putatively regulated by AhR (aryl hydrocarbon receptor) and CAR (constitutive androstane receptor), activated by BP and DDT, respectively. In particular, miR-3577 and -193b were selected as potentially regulated CAR, miR-207 was selected as a candidate for miR under AhR regulation. …”
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677
MicroRNA-1 Inhibits the Growth of Breast Cancer Cells MDA-MB-231 and MCF-7 Treated with Hydatid Cyst Fluid
Published 2024-01-01“…In addition, the expression level of miR-1 in HCF-treated and untreated breast cancer cells was analyzed using qRT-PCR. …”
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678
Research on Correlations of lncRNA ST7-AS1 with Progression and Therapeutic Targets of Esophageal Cancer
Published 2025-02-01“…Mechanistically, ST7-AS1 acted as a sponge for miR-4262, affecting the progression of esophageal cancer. …”
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679
Isolation and study of biological properties of <i>Bordetella bronchiseptica</i>-specific bacteriophages
Published 2022-09-01Get full text
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680
Determining the Potential Roles of Branched-Chain Amino Acids in the Regulation of Muscle Growth in Common Carp (Cyprinus carpio) Based on Transcriptome and MicroRNA Sequencing
Published 2023-01-01“…Our findings revealed the role of atg5, map1lc3c, ctsl, cdc53, psma6, psme2, myl9, and mylk in skeletal muscle growth, protein synthesis, and catabolic metabolism. Furthermore, miR-135c, miR-192, miR-194, and miR-203a may play key roles in maintaining the normal activities of the organism by regulating genes related to muscle growth, protein synthesis, and catabolism. …”
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