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621
Plasma miRNAs in polycystic ovary syndrome drive endometrial cancer progression: insights into molecular pathways and therapeutic targets
Published 2025-02-01“…Twelve of these miRNAs were associated with UCEC overall survival, with miR-142, miR-424, and miR-331 acting as protective factors, while the remaining 9 miRNAs were identified as risk factors. …”
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622
Metastatic melanoma: An integrated analysis to identify critical regulators associated with prognosis, pathogenesis and targeted therapies.
Published 2025-01-01“…MiRNAs analysis revealed hsa-miR-181c-5p, hsa-miR-30b-3p, hsa-miR-3680-3P, hsa-miR-4659a-3p, hsa-miR-4687-3P, and hsa-miR-6808-3P could regulate the hub genes, whereas RP11-553K8.5 and SRP14-AS1 were identified as the top significant lncRNA. …”
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623
Deciphering the Regulatory Network of Some Key Drought-responsive Genes and microRNAs in Canola
Published 2024-02-01“…The hub genes were regulated by vital drought-responsive miRNAs such as miR9558, miR854, miR172, miR834, miR390, and miR167. …”
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624
Genetic Variants of Neurotransmitter-Related Genes and miRNAs in Egyptian Autistic Patients
Published 2013-01-01“…The study also analyzed sequence variations of miR-431 and miR-21. MAOA uVNTR was genotyped by PCR, MAOB and DRD2 polymorphisms were analyzed by PCR-based RFLP, and miR-431 and miR-21 were sequenced. …”
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625
MicroRNA Deregulation in Anaplastic Thyroid Cancer Biology
Published 2014-01-01“…Upregulation of miRNAs, such as miR-146b, miR-221, and miR-222, is observed in ATC and also in differentiated thyroid cancer (papillary and follicular), indicating that these miRNAs’ overexpression is essential in maintaining tumorigenesis. …”
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626
The Search of miRNA Related to Invasive Growth of Nonfunctioning Gonadotropic Pituitary Tumors
Published 2020-01-01“…When miRNA profiles of invasive and noninvasive tumors were compared, 29 miRNAs were found differentially expressed. Hsa-miR-184, hsa-miR-181a-2-3p, hsa-miR-93-3p, hsa-miR-574-5p, hsa-miR-185-5p, and hsa-miR-3200-5p showed a potential clinical value according to ROC curve analysis. …”
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627
Comparison of glimepiride and linagliptin in the treatment of non-alcoholic hepatic disease with type 2 diabetes mellitus
Published 2023-02-01“…This study aimed to determine whether miR-210 can predict the effects of glimepiride and linagliptin on NAFLD with T2DM. …”
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628
MicroRNA-3145 as a potential therapeutic target for hepatitis B virus: inhibition of viral replication via downregulation of HBS and HBX
Published 2025-01-01“…The expression of its precursor, pri-miR-3145, increased in response to the the virus infection, and miR-3145 downregulated the hepatitis B virus S (HBS) antigen and hepatitis B virus X (HBX), thereby inhibiting viral replication. …”
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629
Clinical Evaluation of the Diagnostic Role of MicroRNA-155 in Breast Cancer
Published 2020-01-01“…Biochemical markers, including microRNAs (miRs), may facilitate the diagnosis and prognosis of breast cancer. …”
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630
Mechanism of TGIF1 on glycolipid metabolism disorders in mice with type 2 diabetes
Published 2025-01-01“…TGIF1 was enriched on the miR-106b-5p promoter and promoted miR-106b-5p expression. miR-106b-5p inhibited EGR2 expression. miR-106b-5p inhibition or EGR2 overexpression partially reversed the alleviative effect of TGIF1 overexpression on glycolipid metabolism disorders.Conclusion TGIF1 reduces glycolipid metabolism disorders in mice with T2D through the miR-106b-5p/EGR2 axis.…”
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631
Integrated microRNA and mRNA signatures associated with overall survival in epithelial ovarian cancer.
Published 2021-01-01“…Several interaction pairs between 6 miRNAs (hsa-miR-126-3p, hsa-miR-223-3p, hsa-miR-23a-5p, hsa-miR-27a-5p, hsa-miR-486-5p, and hsa-miR-506-3p) and 8 mRNAs (ATF3, CH25H, EMP1, HBB, HBEGF, NAMPT, POSTN, and PROCR) were identified and the findings appear to be well supported by the literature. …”
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632
Three-dimensional Middle Infrared Spectroscopy Study on Crystalline and Amorphous Structures and Thermostability of Corn, Wheat, and Pea Starch
Published 2025-01-01“…The structure and thermal denaturation of three types of starch, including corn starch, wheat starch, and pea starch, were studied using one-dimensional mid infrared (MIR) spectroscopy, temperature dependent one-dimensional MIR spectroscopy and two-dimensional MIR spectroscopy. …”
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633
Effects of Ginsenoside Biopolymer Nanoparticles on the Malignant Behavior of Non-Small-Cell Lung Cancer
Published 2020-01-01“…Thirdly, the knockdown of miR-192 significantly inhibited H125 cell proliferation, invasion, and migration and also enhanced H125 cell apoptosis. …”
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634
Synthesis and Characterization of Green Zinc Oxide Nanoparticles with Antiproliferative Effects through Apoptosis Induction and MicroRNA Modulation in Breast Cancer Cells
Published 2020-01-01“…In this study, the expression of miR-155-5p, miR-203a-3p, and miR-223-3p in the MCF7 cancer cell line was studied when exposed to ZnO nanoparticles synthesized through a green route. …”
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635
What Is in the Field for Genetics and Epigenetics of Diabetic Neuropathy: The Role of MicroRNAs
Published 2021-01-01“…It summarized the findings of animal and human studies that associate miRNAs with diabetic neuropathy and explored the possible pathogenetic meanings of these associations, in particular regarding miR-128a, miR-155a, and miR-499a, as well as their application for diabetic neuropathy screening. …”
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636
T Cell Subsets and the Expression of Related MicroRNAs in Patients with Recurrent Early Pregnancy Loss
Published 2023-01-01“…In the EPL group, the expression of mir-106b, mir-93, and mir-25 was upregulated (1.51±0.129, 1.43±0.132, and 1.73±0.156, respectively) in regulatory T (Treg) cell-related T cell subsets, whereas the expression of miR-146a and miR-155 was downregulated (P<0.05). …”
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637
Effects of Ubiquinol-10 on MicroRNA-146a Expression In Vitro and In Vivo
Published 2009-01-01“…MicroRNAs (miRs) are involved in key biological processes via suppression of gene expression at posttranscriptional levels. …”
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638
Evaluation of microRNAs as liquid biopsy markers in adrenocortical tumors
Published 2025-01-01“…This study aims to validate the diagnostic performance of selected circulating microRNAs, (miR-483-5p, miR-210, miR-335 and miR-22-3p), identified through microRNA profiling studies, as markers of malignancy or cortisol hypersecretion in a cohort of patients with ATs.MethodsWe collected serum samples from 75 patients with ATs, including 50 cases of adrenocortical adenomas (ACA) and 25 cases of adrenocortical carcinomas (ACC), along with 15 controls. …”
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639
miRNAs and Hematological Markers in Non-Alcoholic Fatty Liver Disease—A New Diagnostic Path?
Published 2025-01-01“…Serological concentrations of miR-126-3p, miR-197-3p, and miR-1-3p were measured in all participants. …”
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640
Extracellular viral microRNAs as biomarkers of virus infection in human cells
Published 2025-03-01“…Viral exmiR profiling of spent media from EBV- and HHV-8-reactivated B cell models revealed specific signatures of elevated EBV miR-BHRF1-2-3p and HHV-8 miR-K12-10a-3p, miR-K12-10b, and miR-K12-12-3p, respectively, during virus reactivation. …”
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