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601
Vitamin D Potentiates the Inhibitory Effect of MicroRNA-130a in Hepatitis C Virus Replication Independent of Type I Interferon Signaling Pathway
Published 2015-01-01“…Intriguingly, this potentiating effect of calcitriol on miR-130a was not through upregulating the expression of cellular miR-130a or through increasing the miR-130a-mediated IFNα/β production. …”
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602
The combined effect of metformin and mirabegron on diet‐induced obesity
Published 2023-04-01“…Metformin (Met) and mirabegron (Mir) cause weight loss by targeting EI and EE, respectively. …”
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603
Metformin Exhibits Anti‐Inflammatory Effects by Regulating microRNA‐451/CXCL16 and B Cell Leukemia/Lymphoma 2 in Patients With Osteoarthritis
Published 2025-01-01“…In this study, we evaluated the ability of metformin to regulate microRNAs, such as miR‐451 and miR‐15b, and their target proteins, CXCL16 and B cell leukemia/lymphoma 2 (BCL‐2), involved in inflammation and apoptosis. …”
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604
Regulation of miRNAs in obesity and diabetes
Published 2023-12-01“…Results: The expression of miR-A, miR-221, miR-222, miR-21, miR-146 and miR-133 were significantly dysregulated in obese and diabetic patients compared to controls. …”
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605
Clinical Effect of Apatinib Mesylate Tablets Combined with Paclitaxel Concurrent Radiotherapy and Chemotherapy in the First-Line Treatment of Locally Advanced Nasopharyngeal Carcin...
Published 2022-01-01“…After treatment, miR-655 in serum increased in both the groups and miR-655 in the research group was higher than that in the control group (P<0.05). …”
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606
Analysis of a mouse germ cell tumor model establishes pluripotency-associated miRNAs as conserved serum biomarkers for germ cell cancer detection
Published 2025-02-01“…Here, we report that miRNAs in the mouse miR-290-295 cluster, homologs of the human miR-371-373 cluster, were detectable in serum from mice with malignant TGCTs but not from tumor-free control mice or mice with benign teratomas. miR-291-293 were expressed and secreted specifically by pluripotent EC cells, and expression was lost following differentiation induced by the drug thioridazine. …”
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607
Analysis of the lncRNA-Associated Competing Endogenous RNA (ceRNA) Network for Tendinopathy
Published 2022-01-01“…Downregulated lncRNA MIR133A1HG could competitively bind with hsa-miR-659-3p and hsa-miR-218-1-3p to regulate the TPM3. …”
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608
Expression and characterization of exosomal miRNAs in healthy, sub-clinical mastitis and pasteurized milk of buffaloes
Published 2025-01-01“…The positive correlation between SCC and miR-148a and miR-186 expression indicates their potential as robust biomarkers for sub-clinical mastitis in buffaloes. …”
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609
Extracellular Vesicles Derived from Human Umbilical Cord Mesenchymal Stem Cells Promote Trophoblast Cell Proliferation and Migration by Targeting TFPI2 in Preeclampsia
Published 2023-01-01“…It has been reported that microRNA-195 (miR-195) is associated with preeclampsia. In this study, we discovered the target of miR-195 in regulating human extravillous cytotrophoblast-derived transformed cell proliferation and migration. …”
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610
An Ex Vivo Study on Release, Uptake, and miRNA Profile of Exosomes in Rat Lens
Published 2022-01-01“…The most abundant miRNAs included miR-184, let-7c-5p, let-7a-5p, let-7b-5p, let-7f-5p, miR-125a-5p, miR-204-5p, miR-125b-5p, miR-1b, and miR-23a-3p. …”
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611
Histone Methyltransferase SETDB1 Promotes Immune Evasion in Colorectal Cancer via FOSB-Mediated Downregulation of MicroRNA-22 through BATF3/PD-L1 Pathway
Published 2022-01-01“…SETDB1 negatively regulated miR-22 expression by downregulating FOSB expression, while miR-22 downregulated PD-L1 expression via targeting BATF3. …”
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612
MicroRNA-32-5p promotes the proliferation and metastasis of gastric cancer cells
Published 2025-01-01“…Clonal formation, MTT, caspase-3 activity, sperm DNA fragmentation, flow cytometry assay, cell adhesion, transwell assays were performed to detect the functions of miR-32-5p or anti-miR-32-5p on the growth and metastasis of GC cells. …”
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613
Harnessing the power of proteins in modulation of miRNAs for targeting Iron deficiency Anemia: Opinion for future implications and strategies
Published 2025-01-01“…Emerging evidence underscores the pivotal role of miRNAs—such as miR-15a, miR-24, miR-150, and miR-223—in regulating erythropoiesis, with dysregulation linked to hematologic and systemic diseases. …”
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614
Potential Value of Circular RNA circTBC1D4 in Gastrointestinal Stromal Tumors
Published 2022-01-01“…The target of TBC1D4 is miR-590-5p, and miR-590-5p increased after knocking down TBC1D4. …”
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615
miRNA Expression Profile and Effect of Wenxin Granule in Rats with Ligation-Induced Myocardial Infarction
Published 2017-01-01“…And, pathway analysis was performed by using the DIANA-miRPath v3.0 online tool. The expressions of miR-1, miR-133, Cx43, and Cx45 were detected by quantitative real-time PCR. …”
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616
Polymorphic Single‐Nucleotide Variants in miRNA Genes and the Susceptibility to Colorectal Cancer: Combined Evaluation by Pairwise and Network Meta‐Analysis, Thakkinstian's Algorit...
Published 2025-01-01“…Additionally, the miR‐196a2 (rs11614913), miR‐143/145 (rs41291957), and miR‐34b/c (rs4938723), with the dominant, recessive, and recessive models identified as the optimal, might confer protective effects against CRC among Asians.…”
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617
Identification of Potential lncRNAs and miRNAs as Diagnostic Biomarkers for Papillary Thyroid Carcinoma Based on Machine Learning
Published 2021-01-01“…The epigenetic modifications via the above diagnostic lncRNAs and miRNAs were identified, including MIR181A2HG-FOXP2-hsa-miR-146b-3p, BLACAT1/ST7-AS1-RPS6KA5-hsa-miR-34a-5p, LBX2-AS1/MIR100HG-CDHR3-hsa-miR-34a-5p, ADD3-AS1-PTPRE-hsa-miR-9-5p, ADD3-AS1-TGFBR1-hsa-miR-214-3p, LINC00506-MMRN1-hsa-miR-4709-3p, and LOC339059-STK32A-hsa-miR-199b-5p. …”
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618
Salivary Biomarkers: Noninvasive Ways for Diagnosis of Parkinson’s Disease
Published 2023-01-01“…Although salivary flow rate is decreased in PD patients, high levels of heme oxygenase and acetylcholinesterase might be used as noninvasive biomarkers. Salivary miRNAs (miR-153, miR-223, miR-874, and miR-145-3p) are novel diagnostic biomarkers that should be given more attention.…”
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619
The Diagnosis Value of a Novel Model with 5 Circulating miRNAs for Liver Fibrosis in Patients with Chronic Hepatitis B
Published 2021-01-01“…Differential expression of five selected miRNAs (hsa-mir-1225-3p, hsa-mir-1238, hsa-miR-3162-3P, hsa-miR-4721, and hsa-miR-H7) was verified by qRT-PCR in the plasma of 83 patients and 20 healthy controls. …”
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620
MicroRNA-208a Dysregulates Apoptosis Genes Expression and Promotes Cardiomyocyte Apoptosis during Ischemia and Its Silencing Improves Cardiac Function after Myocardial Infarction
Published 2015-01-01“…Aims. miR-208a is associated with adverse outcomes in several cardiac pathologies known to have increased apoptosis, including myocardial infarction (MI). …”
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