Altered expression profile of plasma exosomal microRNAs in exclusive electronic cigarette adult users by Dongmei Li, Zidian Xie, Sadiya Bi Shaikh, Irfan Rahman

“…We identified four miRNAs that were upregulated in exclusive e-cigarette users compared to non-users: hsa-miR-100-5p, hsa-miR-125a-5p, hsa-miR-125b-5p, and hsa-miR-99a-5p, after adjusting for the confounding effects of race. …”
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MicroRNAs as Haematopoiesis Regulators by Ram Babu Undi, Ravinder Kandi, Ravi Kumar Gutti

“…Evidence shows that miRNAs play an important role in haematopoiesis; for example, myeloid and erythroid differentiation is blocked by the overexpression of miR-15a. miR-221, miR-222, and miR-24 inhibit the erythropoiesis, whereas miR-150 plays a role in B and T cell differentiation. miR-146 and miR-10a are downregulated in megakaryopoiesis. …”
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Dexmedetomidine Mitigates Microglial Activation Associated with Postoperative Cognitive Dysfunction by Modulating the MicroRNA-103a-3p/VAMP1 Axis by Zhichao Wu, Han Wang, Zuan Shi, Yalan Li

“…In this model, dexmedetomidine reversed miR-103a-3p and VAMP1 expression; this effect was abolished by miR-103a-3p overexpression. …”
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Plasma-derived extracellular vesicles prime alveolar macrophages for autophagy and ferroptosis in sepsis-induced acute lung injury by Rongzong Ye, Yating Wei, Jingwen Li, Yu Zhong, Xiukai Chen, Chaoqian Li

“…Notably, EV-based panels (miR-122-5p, miR-125b-5p, miR-223-3p, OLFM4, and LCN2) have been found to be associated with the severity or prognosis of sepsis, with promising AUC values. …”
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MicroRNA-129-3p Suppresses Tumor Progression and Chemoradioresistance in Head and Neck Squamous Cell Carcinoma by Tae Mi Yoon, Sun-Ae Kim, Eun Kyung Jung, Young-Kook Kim, Kyung-Hwa Lee, Sang Chul Lim

“…(1) Background: MicroRNA-129 (miR-129) participates in tumor progression and chemoresistance in various cancer types. …”
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MicroRNA-132 Interact with p250GAP/Cdc42 Pathway in the Hippocampal Neuronal Culture Model of Acquired Epilepsy and Associated with Epileptogenesis Process by Jinxian Yuan, Hao Huang, Xin Zhou, Xi Liu, Shu Ou, Tao Xu, Ruohan Li, Limin Ma, Yangmei Chen

“…Generally, silencing miR-132 may suppress spontaneous seizure activity through the miR-132/p250GAP/Cdc42 pathway by regulating the morphology and electrophysiology of dendritic spines; therefore, miR-132 may serve as a potential target for the development of antiepileptic drugs.…”
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Cardiac‐peripheral transvenous gradients of microRNA expression in systolic heart failure patients by Inbar Ben‐Zvi, Natalia Volinsky, Liza Grosman‐Rimon, Izhak Haviv, Guy Rozen, Nizar Andria, Nofar Asulin, Nufar Margalit, Ibrahim Marai, Offer Amir

“…The levels of four cardiac specified miRNAs (miR‐21‐5p, miR‐92b‐3p, miR‐125b‐5p, and miR‐133a‐3p) were compared between the peripheral samples of HF and controls and between peripheral venous in CS in the HF groups. …”
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Urinary exosomal miRNA-451a can be used as a potential noninvasive biomarker for diagnosis, reflecting tubulointerstitial damage and therapeutic response in IgA nephropathy by Qiong Zhang, Yan Zhao, Yankun Luo, Songjia Guo, Haizhu Hou, Xiaoli Han, Yun Zhou

“…The expression of miR-451a within exosomes was examined by reverse transcription-quantitative polymerase chain reaction (RT-qPCR). uE miR-451a was significantly upregulated in patients with IgAN compared to non-IgAN and HCs. …”
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MicroRNA-140-5p inhibits cellular proliferation, migration and invasion by downregulating AKT/STAT3/NF-κB pathway in breast carcinoma cells by Hou Lingli, Liu Qi, Zhao Ying, Yang Hongwei, Meng Qingying, Yu Fei

“…MicroRNA-140-5p (miR-140-5p) plays a pivotal role in human cancers. …”
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Identification of Potential miRNA-mRNA Regulatory Network Contributing to Parkinson’s Disease by Xi Yin, Miao Wang, Wei Wang, Tong Chen, Ge Song, Yixuan Niu, Ziying Jiang, Zhongbao Gao, Zhenfu Wang

“…A miRNA-mRNA regulatory network was then constructed with 10 hub genes, and their interacting miRNAs overlapped with DEmis, including miR-30e-5p, miR-142-3p, miR-101-3p, miR-32-3p, miR-508-5p, miR-642a-5p, miR-19a-3p, and miR-21-5p. …”
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Deficiency of MicroRNA-23-27-24 Clusters Exhibits the Impairment of Myelination in the Central Nervous System by Yuji Tsuchikawa, Naosuke Kamei, Yohei Sanada, Toshio Nakamae, Takahiro Harada, Kazunori Imaizumi, Takayuki Akimoto, Shigeru Miyaki, Nobuo Adachi

“…Several microRNAs (miRNAs), including miR-23 and miR-27a have been reportedly involved in regulating myelination in the central nervous system. …”
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Circulating microRNA panels for multi-cancer detection and gastric cancer screening: leveraging a network biology approach by Leila Kamkar, Samaneh Saberi, Mehdi Totonchi, Kaveh Kavousi

“…Results The first panel (hsa-miR-8073, hsa-miR-614, hsa-miR-548ah-5p, hsa-miR-1258) achieved 96.1% accuracy, 96% specificity, and 98.6% sensitivity in multi-cancer screening. …”
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MiRNAs as major players in brain health and disease: current knowledge and future perspectives by Sarika V. Kapplingattu, Sujata Bhattacharya, Yogita K. Adlakha

“…In this review, by performing in silico analysis of molecular targets of miR-135, we reveal the significant pathways and processes modulated by miR-135. …”
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Exosomes Derived from Mesenchymal Stem Cells Ameliorate Hypoxia/Reoxygenation-Injured ECs via Transferring MicroRNA-126 by Qunwen Pan, Yan Wang, Qing Lan, Weiquan Wu, Zhenxuan Li, Xiaotang Ma, Liming Yu

“…In this study, we determined whether EXs released from MSC-EXs provided beneficial effects on hypoxia/reoxygenation- (H/R-) injured ECs by transferring miR-126. MSCs were transfected with a miR-126 mimic or miR-126 short hairpin RNA to obtain miR-126-overexpressing MSC-EXs (MSC-EXsmiR-126) and miR-126 knockdown MSC-EXs (MSC-EXsSimiR-126). …”
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Altered expression of miRNA profile in peripheral blood mononuclear cells following the third dose of inactivated COVID-19 vaccine by Guanguan Qiu, Ruoyang Zhang, Huifeng Qian, Ruoqiong Huang, Jie Xia, Ruoxi Zang, Zhenkai Le, Qiang Shu, Jianguo Xu, Guoping Zheng, Jiangmei Wang

“…Bioinformatic analysis suggested that miR-25-5p, miR-34c-3p, and miR-206 may target multiple pathways involved in immune regulation and inflammation. …”
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Bioinformatics Analysis of miRNAs Targeting TRAF5 in DLBCL Involving in NF-κB Signaling Pathway and Affecting the Apoptosis and Signal Transduction by Chunyao Li, Lanshan Huang, Yongqin Wen, Muhua Yi, Min Gao

“…DEGs were significantly concentrated in the NF-κB signaling pathway and cytokine-cytokine receptor interaction, and involved in the process of immune response and protein binding. MiR-15a-5p, miR-147a, miR-192-5p, miR-197-3p, miR-532-5p, and miR-650 were revealed to be targeting TRAF5 and participating in NF-κB signaling pathway and might impact the apoptosis and signal transduction of DLBCL. …”
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Insight of microRNA role in Colorectal Cancer by Kwan-Liang Lye, Loh Teng-Hern Tan, Hui-Min Yap

“…While miRNAs including miR-17-92 cluster, miR-21, miR-34, miR-135 and miR-196a also exhibited high association with colorectal cancer. …”
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MicroRNA-451a is a candidate biomarker and therapeutic target for major depressive disorder by Yan Chen, Yun Liu, Ming Xiao, Chun Wang, Panpan Hu, Qiuchen Cao, Hu Feng, Jingfan Xu, Weixi Feng, Huaiqing Sun, Huachen Ding, Junying Gao

“…Background Increasing evidence supports the role of microRNAs (miRNAs) in major depressive disorder (MDD), but the pathophysiological mechanism remains elusive.Aims To explore the mechanism of microRNA-451a (miR-451a) in the pathology and behaviours of depression.Methods Abnormal miRNAs such as miR-451a reported previously in the serum of patients with MDD were screened and then confirmed in a mouse model of depression induced by chronic restraint stress (CRS). …”
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Endothelial Cell-Derived Extracellular Vesicles Target TLR4 via miRNA-326-3p to Regulate Skin Fibroblasts Senescence by Xinni Yang, Jiyong Tan, Jiqing Shen, Xin Zhang, Gaoxiang Huang, Xiaoxue Su, Jing Li

“…The target gene of miRNA were identified using a double luciferase reporter assay. miR-326-3p mimic/inhibitor and siRNA-TLR4 can demonstrate a nonnegligible link between miR-326-3p-TLR4 and skin aging. …”
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MicroRNA-223 Expression Is Upregulated in Insulin Resistant Human Adipose Tissue by Tung-Yueh Chuang, Hsiao-Li Wu, Chen-Chun Chen, Gloria Mabel Gamboa, Lawrence C. Layman, Michael P. Diamond, Ricardo Azziz, Yen-Hao Chen

“…Our data indicates that miR-223 is significantly overexpressed in the AT of IR women, regardless of whether they had PCOS or not. miR-223 expression in AT was positively correlated with HOMA-IR. …”
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