The Possibility of Conducting Experiments on Animals. Moral Theologian’s Reflections by Krzysztof Smykowski

“…Also, the number of used animals should be limited and the pain and stress the animals feel ought to be minimized. The right balance should be maintained between those factors. …”
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A Discrete Mathematical Modeling and Optimal Control of the Electoral Behavior with regard to a Political Party by Omar Balatif, Abderrahim Labzai, Mostafa Rachik

“…Also, we propose an optimal strategy for an awareness program or an election campaign that helps politicians to distinguish between different categories of voters in order to increase the participation rate in the electoral process and obtain the greatest possible number of votes with a minimal effort. Pontryagin’s Maximum Principle, in discrete time, is used to characterize the optimal controls and the optimality system is solved by an iterative method. …”
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Optimal Demand Response of Smart Home with PV Generators by Chao-Rong Chen, Ming-Jen Lan

“…The work proposes a users’ load model and the interior point method for optimal scheduling with elastic power utilization to minimize power price. The interior point method has the advantages of rapid convergence and robustness. …”
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Si1−xGex nanowire based metal‐semiconductor‐metal Schottky biristor: Design and sensitivity analysis by Shaleen Nr, Sangeeta Singh, Pankaj Kumar

“…The device performance is investigated with respect to channel doping, electrode work function, channel length, temperature and mole fraction (x) to maximize the latching window size and minimize the latch‐up voltage. The detailed sensitivity analysis is also carried for the proposed device with parametric sweep method.…”
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Biphenotypic Acute Leukemia versus Myeloid Antigen-Positive ALL: Clinical Relevance of WHO Criteria for Mixed Phenotype Acute Leukemia by William A. Hammond, Pooja Advani, Rhett P. Ketterling, Daniel Van Dyke, James M. Foran, Liuyan Jiang

“…The changes in diagnostic criteria influence management by assigning weight to aberrantly expressed markers and minimizing expression of myeloid markers other than myeloperoxidase (MPO), potentially foregoing consolidative allogeneic transplant for an otherwise “favorable” lymphoid phenotypic leukemia. …”
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Laparoscopic Dismembered Pyeloplasty in a Solitary Kidney with Intrarenal Pelvis: Two Challenges in One Case by Akin Soner Amasyali, Erhan Ates, Hakan Görkem Kazici, Alper Nesip Manav, Haluk Erol

“…Laparoscopic pyeloplasty (LP) for ureteropelvic junction obstruction (UPJO) is one of the most appropriate surgical techniques to achieve the optimal goal of minimally invasive surgery. However, urologists hesitate to use the laparoscopic approach in UPJO with solitary kidney or intrarenal pelvis. …”
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CAR-T therapy toxicities: the importance of macrophages in their development and possible targets for their management by Joseph Norton, Patrick Stiff

“…In particular, we discuss the emerging role of the MPS in both the toxicity and efficacy of CAR-T therapy, and possible avenues for the modulation of the MPS to optimize efficacy while minimizing toxicity.…”
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Spatio-temporal patterns with hyperchaotic dynamics in diffusively coupled biochemical oscillators by Gerold Baier, Sven Sahle

“…The systems involved are: (a) a two-variable oscillator with two consecutive autocatalytic reactions derived from the Lotka–Volterra scheme; (b) a minimal two-variable oscillator with one first-order autocatalytic reaction; (c) a three-variable oscillator with first-order feedback lacking autocatalysis. …”
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A Compact Wideband Stacked Antenna for the Tri-Band GPS Applications by Maher M. Abd Elrazzak, M. F. Alsharekh

“…High permittivity dielectric materials are used to minimize the antenna dimensions. The obtained antenna is of dimensions 32×18×2.117 mm. …”
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Vibration Analysis for Monitoring of Ancient Tie-Rods by L. Collini, R. Garziera, K. Riabova

“…The weighed differences between experimentally and numerically determined frequencies are minimized with respect to the parameters of the model, the main being the axial load and the stiffness at the tie-rod/wall interface. …”
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Optimal Impact Isolation for Injury Prevention Evaluated by the Head Injury Criterion by D.V. Balandin, N.N. Bolotnik, J.R. Crandall, W.D. Pilkey, S.V. Purtsezov

“…The deceleration distance is minimized subject to a constraint on the Head Injury Criterion functional. …”
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A Cosmological Scaling Relation for Describing the Late Time Dynamics by Gerardo Cristofano, Orlando Luongo

“…A scaling relation between mass and minimal information of a given system is inferred from primordial black holes. …”
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Defects in castings during high‑pressure casting and measures to prevent their formation by V. I. Chechukha, M. A. Sadokha

“…To ensure high quality of produced castings, it is necessary to minimize the influence of the human factor during the casting process. …”
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Multistep Hybrid Iterations for Systems of Generalized Equilibria with Constraints of Several Problems by Lu-Chuan Ceng, Cheng-Wen Liao, Chin-Tzong Pang, Ching-Feng Wen

“…We first introduce and analyze one multistep iterative algorithm by hybrid shrinking projection method for finding a solution of the system of generalized equilibria with constraints of several problems: the generalized mixed equilibrium problem, finitely many variational inclusions, the minimization problem for a convex and continuously Fréchet differentiable functional, and the fixed-point problem of an asymptotically strict pseudocontractive mapping in the intermediate sense in a real Hilbert space. …”
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Mathematical modeling of glioma therapy using oncolytic viruses by Baba Issa Camara, Houda Mokrani, Evans K. Afenya

“…Based on such approaches and existing work, a spatio-temporal model that describes interaction between tumor cells and oncolytic viruses is developed.Conditions that lead to optimal therapy in minimizing cancer cell proliferation and otherwise areanalytically demonstrated. …”
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Case report: Complete response of recurrent locally advanced basal cell carcinoma following addition of vismodegib to neoadjuvant cemiplimab therapy by Chalette Lambert-Swainston, Wolfram Samlowski, Wolfram Samlowski, Wolfram Samlowski, Brandon Reynolds, Amin Hedayat, Amin Hedayat

“…This patient was treated with neoadjuvant cemiplimab with minimal response. Cautious addition of vismodegib with ongoing cemiplimab treatment was well tolerated and resulted in significant tumor regression. …”
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Research on Optimization of Customized Bus Routes Based on Uncertainty Theory by Zi Sang, Bing Zhang, Yunqiang Xue, Hongzhi Guan

“…In this study, the uncertainty theory is introduced into the optimization problem of a customized bus route, and an uncertain customized bus route optimization model is established, which aims at the minimizing the total mileage of vehicle operation. An improved genetic algorithm is used to solve the model, whose feasibility is verified by a case study. …”
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Les élections locales 2013 en Côte d’Ivoire : des malentendus subsistent sur l’exercice de la démocratie by Christian Bouquet, Irène Kassi-Djodjo

“…Fortunately, the issues were minimal due the fact that the decentralization is still largely virtual.…”
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Complications Using Bioabsorbable Cross-Pin Femoral Fixation: A Case Report and Review of the Literature by Saqib Hasan, Samir Nayyar, Ikemefuna Onyekwelu, Kunal Kalra, Soterios Gyftopoulos, Laith M. Jazrawi

“…Although numerous biomechanical studies have demonstrated high fixation strength and minimal slippage with use of this method of fixation, there have been increasing reports of a variety of clinical complications associated with these implants. …”
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Intracavitary Irradiation as a Safe Alternative for Cystic Craniopharyngiomas: Case Report and Review of the Literature by Alejandro Enriquez-Marulanda, Melibea Sierra-Ruiz, Luz Maritza Pabón, Javier Lobato-Polo

“…There are many treatment alternatives; however one of them (intracavitary irradiation) seeks to control this type of benign brain tumor using minimally invasive techniques, with the specific aim of avoiding causing significant damage to important structures surrounding the sellar/suprasellar region. …”
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