Universal conditional networks (UniCoN) for multi-age embryonic cartilage segmentation with Sparsely annotated data by Nishchal Sapkota, Yejia Zhang, Zihao Zhao, Maria Jose Gomez, Yuhan Hsi, Jordan A. Wilson, Kazuhiko Kawasaki, Greg Holmes, Meng Wu, Ethylin Wang Jabs, Joan T. Richtsmeier, Susan M. Motch Perrine, Danny Z. Chen

“…On average, we achieve a 1.7% Dice score increase with minimal computational overhead and a 7.5% improvement on unseen data. …”
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Identification of robust and abundant reference transcripts for EV mRNA cargo normalization by Antje M. Zickler, Radosław Grochowski, André Görgens, Erik Bäcklin, Maximilian Kordes, J.-Matthias Löhr, Joel Z. Nordin, Samir EL Andaloussi, Daniel W. Hagey

“…To judge the applicability of these genes as reference transcripts for biomarker studies, we performed RNA-sequencing on EVs isolated from plasma by differential ultracentrifugation, and four other minimally processed biofluids. These findings confirm the applicability of these genes as molecular standards for EV-mRNA analysis and will aid in the standardization of EV research by establishing molecular reference genes that can be employed in diverse contexts.…”
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Structural performance of lightweight fibre-reinforced oil palm shell concrete subjected to impact loadings under varying boundary conditions by Idris Ahmed Ja'e, Zakaria Che Muda, Agusril Syamsir, Chiemela Victor Amaechi, Hamad Almujibah, Ali.E.A. Elshekh, Maaz Osman Bashir, Abdulrazak H. Almaliki

“…However, these only had a minimal influence on controlling crack length and width, and did not result in reasonable improvement of the residual strength. …”
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Maternal Hepatitis B Infection Burden, Comorbidity and Pregnancy Outcome in a Low-Income Population on the Myanmar-Thailand Border: A Retrospective Cohort Study by Marieke Bierhoff, Chaisiri Angkurawaranon, Aung Myat Min, Mary Ellen Gilder, Nay Win Tun, Arunrot Keereevijitt, Aye Kyi Win, Elsi Win, Verena Ilona Carrara, Tobias Brummaier, Cindy S. Chu, Laurence Thielemans, Kanlaya Sriprawat, Borimas Hanboonkunupakarn, Marcus Rijken, François Nosten, Michele van Vugt, Rose McGready

“…Hepatitis B virus (HBV) was believed to have minimal impact on pregnancy outcomes apart from the risk of perinatal transmission. …”
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Examining future spatiotemporal changes in blue and green water using an enhanced SWAT model: A Jialing River basin case study by Mingyan Wu, Fuquan Ni, Yu Deng, Nan Jiang, Mengyu Zhu, Huazhun Ren, Ziying Yue, Yuxuan Wang

“…The findings indicate that: (1) The enhanced CO2-SWAT model minimizes uncertainty in future projections and details alterations in blue and green water within these projections. (2) In the future, higher precipitation and temperature indicate a trend towards warmer and wetter conditions. …”
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Incidence of constrained condylar and hinged knee implants and mid- to long-term survivorship: a register-based study from the Nordic Arthroplasty Register Association (NARA) by Jake von Hintze, Ville Ponkilainen, Annette W-Dahl, Nils P Hailer, Ove Furnes, Anne M Fenstad, Mona Badawy, Alma B Pedersen, Martin Lindberg-Larsen, Mika J Niemeläinen, Keijo Mäkelä, Antti Eskelinen

“…Kaplan–Meier (K–M) survival and flexible parametric survival model (FPSM) analyses were performed to estimate revision risk, expressed as hazard ratio (HR) with 95% confidence intervals (CI), with minimally stabilized (MS) TKA acting as the control group (n = 456,137). …”
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Shaping Ability of XP Endo Shaper File in Curved Root Canal Models by Abdulmohsen Alfadley, Abdalrhman Alrajhi, Hamad Alissa, Faisal Alzeghaibi, Lubna Hamadah, Khalid Alfouzan, Ahmed Jamleh

“…In short, XPS and WOG files can be used in shaping severely curved canals as they showed the ability to maintain the original shape with minimal transportation. Both file systems showed signs of deformation after use with a lower number of deformed files observed in WOG throughout the experiment.…”
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Reducing the dietary starch:protein ratios in low-protein diets enhanced the growth performance of goslings from 1 to 28 days of age by Xucheng Zheng, Qian Lu, Chunhui Huang, Usman Nazir, Zhi Yang, Haiming Yang, Zhiyue Wang

“…Protein at 18% level, minimized serum total cholesterol (TC) in goslings. …”
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Circulating tumor DNA for surveillance in high-risk melanoma patients: a study protocol by Magnús P.B. Obinah, Sarah A. Al-Halafi, Karin Dreisig, Tim S. Poulsen, Christoffer Johansen, Thomas Litman, Stig E. Bojesen, Estrid Høgdall, Annette H. Chakera, Lisbet R. Hölmich

“…This study examines ctDNA detection in blood as a minimally invasive method for early identification of progression following primary treatment of melanoma. …”
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Human soft tissue sarcomas harbor an intratumoral viral microbiome which is linked with natural killer cell infiltrate and prognosis by William J Murphy, Robert J Canter, Nikhil Joshi, Sean J Judge, Morgan A Darrow, Steve W Thorpe, Alicia A Gingrich, Lauren M Perry, Sylvia M Cruz, Kara T Kleber, Louis B Jones, Ugur N Basmaci, Matthew L Settles, Blythe P Durbin-Johnson, Arta Monir Monjazeb, Janai Carr-Ascher, Jonathan A Eisen

“…We sought to characterize the intratumoral microbiome in patients with STS undergoing preoperative radiotherapy and surgery, hypothesizing the presence of a distinct intratumoral microbiome with potentially clinically significant microbial signatures.Methods We prospectively obtained tumor and stool samples from adult patients with non-metastatic STS using a strict sterile collection protocol to minimize contamination. Metagenomic classification was used to estimate abundance using genus and species taxonomic levels across all classified organisms, and data were analyzed with respect to clinicopathologic factors.Results Fifteen patients were enrolled. …”
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Global, regional and national burdens of cardiovascular disease attributable to secondhand smoke from 1990–2019: an age-period-cohort analysis by Hong Jiang, Xiang-Bin Pan, Xiaofei Li, Shouzheng Wang, Zeye Liu, Peijian Wei, Fengwen Zhang, Wen-Bin Ou-yang

“…Notably, a higher Sociodemographic Index (SDI) correlated with a greater reduction in mortality, exhibiting a significant 39.1% decrease in high SDI areas (95% UI: 35.6%–42.3%), in stark contrast to the minimal change observed in low SDI areas (0.1%, 95% UI: −52.4%–62.2%).Conclusions This study highlights the importance of considering secondhand smoke as a modifiable CVD risk. …”
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Study on Roof-Coal Caving Characteristics with Complicated Structure by Fully Mechanized Caving Mining by Yunpei Liang, Lei Li, Xuelong Li, Kequan Wang, Jinhua Chen, Zhongguang Sun, Xuelin Yang

“…The probability of coal arch formation with an extraction-caving ratio of 3 is minimal, about 0.4, which is due to that the arch span is large and the curvature is small, so it is difficult to form a stable arch structure. …”
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Robotic Versus Laparoscopic Liver Resection: A Nationwide Propensity Score Matched Analysis by Gabriela Pilz da Cunha, MD, Jasper P. Sijberden, MD, PhD, Susan van Dieren, PhD, Paul Gobardhan, MD, PhD, Daan J. Lips, MD, PhD, Türkan Terkivatan, MD, PhD, Hendrik A. Marsman, MD, PhD, Gijs A. Patijn, MD, PhD, Wouter K. G. Leclercq, MD, PhD, Koop Bosscha, MD, PhD, J. Sven D. Mieog, MD, PhD, Peter B. van den Boezem, MD, PhD, Maarten Vermaas, MD, PhD, Niels F. M. Kok, MD, PhD, Eric J. T. Belt, MD, PhD, Marieke T. de Boer, MD, PhD, Wouter J. M. Derksen, MD, PhD, Hans Torrenga, MD, PhD, Paul M. Verheijen, MD, PhD, Steven J. Oosterling, MD, PhD, Arjen M. Rijken, MD, PhD, Marielle M. E. Coolsen, MD, PhD, Mike S. L. Liem, MD, PhD, T.C. Khé Tran, MD, PhD, Michael F. Gerhards, MD, PhD, Vincent Nieuwenhuijs, MD, PhD, Mohammad Abu Hilal, MD, PhD, Marc G. Besselink, MD, PhD, Ronald M. van Dam, MD, PhD, Jeroen Hagendoorn, MD, PhD, Rutger-Jan Swijnenburg, MD, PhD, for the Dutch Hepatobiliary Audit Group

“…To compare nationwide outcomes of robotic liver resection (RLR) with laparoscopic liver resection (LLR). Background:. Minimally invasive liver resection is increasingly performed using the robotic approach as this could help overcome inherent technical limitations of laparoscopy. …”
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Electronic Playback Devices to Reduce Ungulates’ Attendance in an Olive Grove Farm in the Province of Florence (Italy) by Leonardo Conti, Giulia Angeloni, Piernicola Masella, Caterina Sottili, Ferdinando Corti, Stefano Camiciottoli, Veronica Racanelli, Agnese Spadi, Francesco Garbati Pegna, Alessandro Parenti

“…Balancing human and wildlife needs is crucial for minimizing damage and ensuring coexistence. (2) Methods: This study tested innovative electronic playback devices using long-range radio technology (LoRa) to deter wild ungulates and prevent crop damage. …”
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Optimization, characterization and biosafety of oregano, rosemary and mint oil mixture against Penicillium digitatum in citrus using L-optimal mixture design by Rahaf Khaled, Sara Mohamed, Amira Mohamed, Aya Khairy, Hesham Elhariry, Ashraf Bakry, Neima K. Elsenosy, Naglaa Ebeed, Salem S. Salem, Thanaa ElNoby, Samah H. Abu-Hussien

“…However, the optimized mixture did not induce significant chromosomal aberrations compared to the control, suggesting minimal genotoxic effects. In vivo, evaluation on oranges revealed 60% inhibition of green mold by the 1% (v/v) optimized mixture for 7 days. …”
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Design and Construction of an Aquaponics System: A Sustainable Approach to Enhancing Local Food Security in Offa, Nigeria by Rofiat Bunmi Mudashiru, Maryam Yusuf-Olawuyi, Aliyu Tijani, Lateef Umar, Francis Okeke, Oluwabunmi Adeyemi, Ismaila Amototo, Fatai Salaudeen

“…Aquaponics provides a conservative technique that integrates both hydroponics and aquaculture in regions with minimal arable land. This current study aims to design and build an aquaponics system that is suitable and beneficial to its environment. …”
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Investigating the feasibility of developing a collective action for biological control of fall armyworm among smallholder farmers in rural communities of Zambia by Léna Durocher-Granger, Sara Fiorito, Sibajene Kambanja Mudenda, Milimo Mildred Chiboola, Monica K. Kansiime, David Ludwig, Cees Leeuwis

“…Results Our results showed that some conditions are already in place to support a collective action to manage fall armyworm such as matching rules to local conditions, collective-choice arrangement, conflict-resolution mechanism and minimal recognition of rights to organize which are supported by traditional leadership of the communities. …”
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Depth-Dependent Cellular Response from Dental Bulk-Fill Resins in Human Dental Pulp Stem Cells by Su-Min Lee, Soo-Youn Kim, Jae-Heon Kim, Soo-Kyung Jun, Hae-Won Kim, Jung-Hwan Lee, Hae-Hyoung Lee

“…The proper choice of dental composite resins is necessary based on the minimal cytotoxicity and antiodontogenesis on human dental pulp stem cells for dental pulp-dentin tissue repair and regeneration. …”
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Postoperative Complications of Laparoscopic Total Gastrectomy versus Open Total Gastrectomy for Gastric Cancer in a Meta-Analysis of High-Quality Case-Controlled Studies by Mikito Inokuchi, Sho Otsuki, Norihito Ogawa, Toshiro Tanioka, Keisuke Okuno, Kentaro Gokita, Tatsuyuki Kawano, Kazuyuki Kojima

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A novel 2D nickel coordination polymer based on Trimesic acid with glyphosate coordination capabilities by João M. R. Gonçalves, Ademar Wong, Pedro H. O. Santiago, Guilherme Arroyos, Augusto H. Piva, Javier A. Ellena, Benedito S. Lima-Neto, Regina C. G. Frem

“…This new structure was characterized using Single Crystal X-ray Diffraction (SCXRD), exhibiting a MOF (metal–organic framework) structure, with a minimal formula of {[Ni(HBTC)(DMF)₂]·xDMF}. The structure exhibits a 2D network expanding in the equatorial direction, where the Ni(II) center is hexacoordinated and N,N'-dimethylformamide (DMF) solvent molecules are coordinated along the axial axis. …”
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