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6301
Advanced progress in the genetic modification of the oncolytic HSV-1 virus
Published 2025-01-01“…The HSV-1 genome can be modified through genetic engineering in two main ways: first, by reducing infectivity and toxicity to normal cells via limited replication and assembly, altered protein-virus receptor binding, and minimized immune evasion; second, by enhancing anticancer activity through disruption of tumor cell metabolism, induction of autophagy, improved immune recognition, and modification of the tumor microenvironment. …”
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6302
Sample Tracking Tool: A Comprehensive Approach Based on OpenArray Technology and R Scripting for Genomic Sample Monitoring
Published 2025-01-01“…In conclusion, this method represents a valuable example for promoting laboratory centralization and minimizing the risks related to different laboratory procedures and the management of a high number of samples.…”
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6303
Enhancing decay resistance and maintaining quality of stored apples (Malus domestica ‘Golden Delicious’) through essential oil-enriched edible coatings
Published 2025-03-01“…Therefore, it is critical to develop strategies that minimize weight loss while maintaining quality. Research method: Golden Delicious apples were coated with an edible mixture of Aloe vera gel (ALV) with or without Zataria multiflora essential oil (ZMO). …”
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6304
Influence of Physicochemical Properties of Oil Sludge on Syngas Production for Energy Applications
Published 2024-12-01“…OS is a persistent waste requiring gasification treatment, offering a promising solution that converts these residues into valuable syngas for energy conversion with minimal environmental impact.…”
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6305
Integrated omics revealed the altered colonic microenvironment after inhibition of peripheral serotonin synthesis by LP533401
Published 2024-12-01“…Metagenome profiling revealed an upregulation in the microbial two‐component system (ko02020) and tyrosine metabolism (ko00350), with minimal effects on taxa abundances. Transcriptome profiling analysis indicated the discriminant expression of genes enriched in pathogen infection‐responsive signaling (e.g., Salmonella and Yersinia infection) and the Wnt signaling pathway that affected stem cell proliferation. …”
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6306
Charge-on-the-move solutions for future mobility: A review of current and future prospects
Published 2025-01-01“…Dynamic charging enables EVs to recharge while in motion, presenting opportunities to minimize battery sizes, reduce emissions, and optimize operational efficiency. …”
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6307
Focusing on the mechanism of glycinin-soybean lipophilic protein hybrid gels: Effect of ultrasonic, subunit interactions, and formation process analysis
Published 2025-02-01“…Addition of the A- and B-subunits before and after ultrasonic minimally affected SLP secondary structure. A-subunit addition before ultrasonic negligibly affected SLP tertiary structure. …”
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6308
Towards fiscal sustainable practices in Mexico: The quality of municipal tax regulation and tiered tariffs improve income from solid waste management services
Published 2025-04-01“…The results demonstrate that municipalities with higher levels of tax regulation achieve significantly greater per capita income from SWM services compared to those with minimal or no regulation. Differentiated tariffs based on socioeconomic status were found to be particularly effective, generating income levels 3.29 times higher than uniform tariffs. …”
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6309
Nonlocal Huygens’ meta-lens for high-quality-factor spin-multiplexing imaging
Published 2025-01-01“…Enhanced polarization conversion efficiency of 65% is achieved, accompanied by a minimal unconverted value, surpassing the theoretical limit of traditional thin nonlocal metasurfaces. …”
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6310
Comparing Open and Robotic Unilateral Transversus Abdominis Release in Incisional Hernias With a Lateral Component: A Single Center Retrospective Study
Published 2025-02-01“…With the insurgence of robot assisted abdominal wall surgery, these defects have been found more manageable through a minimal invasive repair. In this study, we aim to present our short-term results of incisional hernia repair with a lateral component requiring a unilateral transversus abdominis release, through open surgery versus robot assisted.MethodsA retrospective analysis was performed of our robotic and open abdominal wall repairs of lateral hernias, where a unilateral transversus abdominis release was performed, between January 2017 and December 2023. …”
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6311
Coloration and functionalization of organic cotton fabric using Chinese fringe leaf extraction: A greener approach
Published 2025-03-01“…The dyed OCF also demonstrated superior UV protection, with an Ultraviolet Protection Factor (UPF) value of 59.19 ± 1.82, and minimal UV transmission in the UV−A and UV−B regions. …”
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6312
Quantitative Analysis of Energy Storage Demand in Northeast China Using Gaussian Mixture Clustering Model
Published 2025-01-01“…A joint optimization model for energy storage and thermal power is developed to optimize power allocation for peak shaving and frequency regulation at minimal cost. The empirical distribution method quantifies the relationship between storage power, capacity, and confidence levels, providing insights into the region’s future energy storage demands. …”
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6313
Toward Integrating ChatGPT Into Satellite Image Annotation Workflows: A Comparison of Label Quality and Costs of Human and Automated Annotators
Published 2025-01-01“…Routing low-certainty images to human annotators can cut total annotation costs by over 50% with minimal impact on label quality. We discuss implications regarding the economic competitiveness of annotation strategies, prompt engineering, and the task-specificity of expertise.…”
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6314
A Stochastic Programming Approach for Scheduling Extra Metro Trains to Serve Passengers from Uncertain Delayed High-Speed Railway Trains
Published 2020-01-01“…The problem is complex because (i) the arrival of delayed HSR trains is usually uncertain, and (ii) the operator has to minimize operating costs (i.e., number of additional trains and operation-ending time) but maximize the number of served passengers, which are two conflicting objectives. …”
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6315
Treatment Effects of Upper Limb Action Observation Therapy and Mirror Therapy on Rehabilitation Outcomes after Subacute Stroke: A Pilot Study
Published 2020-01-01“…Descriptive analyses and the number of patients whose change score achieved minimal clinically important difference were reported. …”
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6316
Nowcasting of a Warm‐Sector Rainfall Event in Southern China With the TRAMS Model: Sensitivity to Different Radar Reflectivity Retrieval Methods and Incremental Updating Strategies...
Published 2025-01-01“…However, the impact of different retrieval methods is minimal without corresponding adjustments to the dynamic field. …”
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6317
Optimization of microprobe analysis of cementitious materials incorporating glass powder under electron beam to avoid alkali migration
Published 2025-03-01“…Due to the lack of a tailored protocol for EPMA analysis of alkali-rich SCMs, this study established analytical conditions to minimize errors in quantifying pozzolanic GP. Mixed glass culets and GP particles embedded in 7-year-old ternary concrete made with GP and silica fume were analyzed using ten different current densities by varying beam size, current, and the sub-counting method. …”
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6318
Multimodal treatments and the risk of breast cancer-related lymphedema: insights from a nationally representative cohort in South Korea
Published 2025-01-01“…Our findings suggest that multidisciplinary strategies are required to minimize the risk of BCRL development in patients with breast cancer.…”
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6319
Vaginal hysterectomy versus vaginal assisted NOTES hysterectomy (VANH): a protocol for a randomised controlled trial
Published 2022-07-01“…Introduction Natural Orifice Transluminal Endoscopic Surgery is a minimal invasive technique using natural body orifices like the vagina. …”
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6320
Improving dexamethasone drug loading and efficacy in treating rheumatoid arthritis via liposome: Focusing on inflammation and molecular mechanisms
Published 2025-01-01“…Liposomal delivery of DEX, particularly when liposomes are surface‐modified with targeting ligands like peptides or sialic acid, can improve drug efficacy by enhancing its distribution to inflamed joints and minimizing toxicity. This study investigates the potential of liposomal drug delivery systems to enhance the efficacy and targeting of DEX in the treatment of RA. …”
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