Impact of frequent ARID1A mutations on protein stability provides insights into cancer pathogenesis by Rajen K. Goutam, Gangtong Huang, Exequiel Medina, Feng Ding, William J. Edenfield, Hugo Sanabria

“…By combining computational stability from web server tools, the structural dynamics from replica exchange discrete molecular simulation (rexDMD), and thermal and chemical denaturation experiments, we found that the R1020S mutation severely decreases structural stability, making it the most impactful, while M1022K has minimal effect, and others lie in between. These findings enhance our understanding of the structural-functional relationship of ARID1A missense mutations at the molecular levels and their role in cancer pathogenesis. …”
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AI Can Be a Powerful Social Innovation for Public Health if Community Engagement Is at the Core by Alessandra N Bazzano, Andrea Mantsios, Nicholas Mattei, Michael R Kosorok, Aron Culotta

“…These actions will support the application of AI to varied public health domains through a framework for more transparent, responsive, and equitable use of this evolving technology, augmenting the work of public health practitioners and researchers to improve health outcomes while minimizing risks and unintended consequences.…”
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Detection of Prunus Necrotic Ringspot Virus (PNRSV) and Apple Mosaic Virus (ApMV) in Rose (Rosa spp.) Plants in Konya Province by Adile Tuğçe Orhan, Serkan Yeşil

“…These results will serve as an important source of information for rose producers and agricultural engineers in the region and will allow the development of strategies to control the spread of viruses and minimize infections.…”
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Effectiveness Model of Coastal Forest in Pananjung Nature Reserve, Pangandaran as Tsunami Buffer by Denni Susanto, Lies Rahayu Wijayanti Faida, Sunarto Sunarto

“…The presence of coastal forest in the Pananjung Nature Reserve reduced the force of the tsunami so that the destructive effect of the tsunami can be minimized. This research aimed to model and assess the effectiveness of coastal forest in Pananjung Nature Reserve as a tsunami buffer. …”
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An Optimization Method for the Train Service Network Design Problem by Jie Xiao, Yi Xie, Haowei Yu, Hongying Yan

“…The objective of the model is to optimize the transportation of all the shipments with minimal costs. The costs consist of accumulation costs, classification coststrain operation costs, and train travel costs. …”
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A feasibility study on bamboo – PLA composite lamina using the mechanics of composite materials by B. Vishwash, K.B. Sachidananda, N.D. Shivakumar

“…We found that there was a critical fibre volume percentage of 8.2 % and a minimal fibre volume fraction of 7.3 %. We discuss the BF-PLA lamina and the applicability in designing facesheets for sandwich composite construction. …”
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Use of Healthcare Claims Data to Generate Real-World Evidence on Patients With Drug-Resistant Epilepsy: Practical Considerations for Research by Nicole Stamas, Tom Vincent, Kathryn Evans, Qian Li, Vanessa Danielson, Reginald Lassagne, Ariel Berger

“…However, as real-world data sources used to generate RWE are typically generated for reasons other than research, rigorous methodology is required to minimize bias and fully unlock their value.…”
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Evaluating Metabolic Profiling of Human Milk Using Biocrates MxP^® QUANT 500 Assay by Daniela Hampel, Setareh Shahab-Ferdows, Gilberto Kac, Lindsay H. Allen

“…<b>Conclusions:</b> The MxP Quant^® 500 assay is a useful tool for HM metabolic profiling, minimizing analytical bias between matrices, and enhancing our ability to study milk as a biological system.…”
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Optimizing humidification–dehumidification desalination systems: Impact of nozzle position and geometric configuration on performance and efficiency by Mohammad Alrbai, Ahmad Al Masri, Dareen Makawii, Ali Alahmer

“…The humidification-dehumidification (HDH) desalination system is an effective solution for sustainable water production due to its low energy consumption and minimal environmental impact. This study explores the performance optimization of HDH systems by analyzing nozzle positioning, geometric configurations, and thermodynamic efficiency. …”
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A Day Ahead Electrical Appliance Planning of Residential Units in a Smart Home Network Using ITS-BF Algorithm by Amir Ali Dashtaki, Morteza Khaki, Mohammad Zand, Mostafa Azimi Nasab, P. Sanjeevikumar, Tina Samavat, Morteza Azimi Nasab, Baseem Khan

“…Accordingly, this article proposes a user-oriented multi-objective approach, which minimizes energy costs and maximizes consumer privacy. …”
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Flexible, Front-Facing Luminescent Solar Concentrators Fabricated from Lumogen F Red 305 and Polydimethylsiloxane by Ian A. Carbone, Katelynn R. Frawley, Melissa K. McCann

“…Light collection was minimally impacted by moderate bending in both LSC designs, suggesting that flexible, front-facing devices could be effectively deployed on curved and uneven surfaces. …”
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Effect of the B chromosome-located long non-coding RNAs on gene expression in maize by Xin Liu, Wenjie Yue, Shiqi Lin, Yuxian Yang, Tong Chen, Xiaowen Shi

“…The maize B chromosome, which is dispensable and highly heterochromatic, has minimal impact on phenotypes at low copy numbers, making it a promising platform for engineering artificial chromosomes. …”
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Development and laboratory evaluation of a novel IoT-based electric-driven metering system for high precision garlic planter. by Abdallah Elshawadfy Elwakeel, Ahmed Elbeltagi, Ahmed Z Dewidar, Ali Salem, Mohamed Anwer Abdeen

“…Additionally, the EDMS minimized the MR up to 3.77% at the same operating velocity, with standard division and standard error of 1.65325 and 0.73936, respectively. …”
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Food recalls: An unnecessary and preventable factor in food waste by Rubén Morawicki

“…Recalls take place after the products have left the processing facility and are no longer under the processor’s control, and their primary goal is to minimize harm by retrieving as much product as possible from the market. …”
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Impact of type 2 diabetes mellitus on results in the animal naming test in patients with and without liver cirrhosis. by Eva Maria Schleicher, Julia Tuchscher, Matthias Weber, Peter Robert Galle, Marcus-Alexander Wörns, Simon Johannes Gairing, Christian Labenz

“…The simplified Animal Naming Test (S-ANT1) has been established for detecting minimal HE (MHE). It is currently unknown whether S-ANT1 results are affected by diabetes mellitus in patients with and without cirrhosis.…”
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Mixed fungal strains challenge host resistance: insights into Magnaporthiopsis maydis pathogenicity in maize by Galia Shofman, Galia Shofman, Ofir Degani, Ofir Degani

“…In contrast, resistant cultivars were minimally affected, except when exposed to a highly aggressive isolate, resulting in a 5% growth suppression and 11% mortality at harvest. …”
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Exclusive displaced hadronic signatures in the LHC forward region by Xabier Cid Vidal, Yuhsin Tsai, Jose Zurita

“…We also apply this projected bound to two scenarios with Higgs portal couplings, where the scalar mediator S either couples to a) the SM quarks only, or b) to both quarks and leptons in the minimal flavor violation paradigm. In both scenarios we compare the reach of our proposed search with the expected constraints from ATLAS and CMS on the invisible Higgs width and with the constraints from rare B-decays studies at LHCb. …”
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A Universal Analysis Pipeline for Hybrid Capture-Based Targeted Sequencing Data with Unique Molecular Indexes by Min-Jung Kim, Si-Cho Kim, Young-Joon Kim

“…Unique molecular index (UMI) technology has recently been developed and helps to increase the accuracy of variant calling by minimizing polymerase chain reaction biases and sequencing errors. …”
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Sandwich structures with TPMS core and printed circuit board faces by Gustavo Ferreira Malta, Pedro Henrique dos Santos Alves, Manuel Barcelos Júnior

“…However, new geometric core configurations, as well as alternative materials and manufacturing processes, are being studied for space applications. Triply Periodic Minimal Surfaces (TPMS) are lattice structures composed of periodic surface structures in three independent directions. …”
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Robotic Subtotal Cholecystectomy in a Geriatric Acute Care Surgery Patient with Super Obesity by Diane Bronikowski, Dominic Lombardo, Connie DeLa’O, Nova Szoka

“…In this case, robotic assisted cholecystectomy console improved surgeon ergonomics and provided support for proper instrumentation. Robotic, minimally invasive cholecystectomy approaches may reduce perioperative morbidity in patients with super obesity. …”
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