Emerging role of exosomes in cancer therapy: progress and challenges by Jiale Li, Jiachong Wang, Zigui Chen

“…As small extracellular vesicles, exosomes exhibit high biocompatibility and low immunogenicity, making them ideal drug delivery vehicles capable of efficiently targeting cancer cells, minimizing off-target damage and side effects. This review aims to explore the potential of exosomes in cancer therapy, with a focus on applications in chemotherapy, gene therapy, and immunomodulation. …”
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Speed-up Technique in Time-Varying Shortest Path Problems with Arbitrary Waiting Times by Gholamhasan Shirdel, Hasan Rezapour

“…The problem is to find the shortest paths from a specific vertex (which is called a source) to other vertices, so that the total cost of the path is minimized and the total travel times and waiting times reach a maximum value of T, where T is a given positive integer. …”
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Collaborative Exploration with a Micro Aerial Vehicle: A Novel Interaction Method for Controlling a MAV with a Hand-Held Device by David Pitman, Mary L. Cummings

“…To this end, we developed the Micro Aerial Vehicle Exploration of an Unknown Environment (MAV-VUE) interface, which allows operators with minimal training the ability to remotely explore their environment with a MAV. …”
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Methodology for the Automatic Generation of Optimization Models of Systems of Flexible Energy Resources by Lukas Peter Wagner, Felix Gehlhoff, Lasse Matthias Reinpold, Georg Frey, Julian Jepsen, Alexander Fay

“…The efficacy of this methodology is demonstrated in two case studies, highlighting its relevance and ability to significantly streamline the optimization modeling process by minimizing the need for manual intervention.…”
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Information-theoretic bounds for accuracy of letter encoding and pattern recognition via ensembles of datasets M.M. Lange 1, A.M. Lange 1 by M.M. Lange, A.M. Lange

“…For these models, the minimal values of the average mutual information between a given ensemble of datasets and the corresponding set of possible decisions are constructed as the appropriate monotonic decreasing functions of a given admissible error probability. …”
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Research on Loading and Unloading Resource Scheduling and Optimization of Rail–Road Transportation in Container Terminal Based on “Internet +” —for Ghana Container Port Development... by Qi Zhang, Adjei Courage Kwabla, Yanhui Zhuang, Mingjun Ling, Yuguang Wei, Hao Yang

“…Under the premise of the scheduled arrival time and quantity of the truck, this paper aims at minimizing the working time of the loading and unloading equipment and the stay time of the train and truck in the station, and develops a scheduling optimization of loading and unloading model combing equilibrium assignment and flexible scheduling to realize the seamless transfer between rail and road transportation in container terminal. …”
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A New In Vivo Model System to Assess the Toxicity of Semiconductor Nanocrystals by Angela Tino, Alfredo Ambrosone, Lucia Mattera, Valentina Marchesano, Andrei Susha, Andrey Rogach, Claudia Tortiglione

“…In the emerging area of nanotechnology, a key issue is related to the potential impacts of the novel nanomaterials on the environment and human health, so that this technology can be used with minimal risk. Specifically designed to combine on a single structure multipurpose tags and properties, smart nanomaterials need a comprehensive characterization of both chemicophysical properties and adequate toxicological evaluation, which is a challenging endeavour; the in vitro toxicity assays that are often employed for nanotoxicity assessments do not accurately predict in vivo response. …”
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Cognitive Code-Division Channelization with Admission Control by Kanke Gao, Onur Ozdemir, Dimitris A. Pados, Stella N. Batalama, Tommaso Melodia, Andrew L. Drozd

“…Our objective is to find the maximum number of admitted secondary links and then find the optimal transmitting powers and code sequences of those secondary links such that the total energy consumption of the secondary network is minimized subject to the conditions that primary interference temperature constraints, secondary signal-to-interference-plus-noise ratio (SINR) constraints and secondary peak power constraints are all satisfied. …”
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Implant-Prosthetic Rehabilitation in Bilateral Agenesis of Maxillary Lateral Incisors with a Mini Split Crest by M. M. Figliuzzi, A. Giudice, S. Pileggi, D. Pacifico, M. Marrelli, M. Tatullo, L. Fortunato

“…In the case we reported, because of the poor bone thicknesses, we performed a minimally invasive split crest which allowed a correct insertion of the fixtures. …”
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Flapless Cone Beam Computed Tomography-Guided Implant Surgery with Contextual Transcrestal Sinus Lift Augmentation Using New Bone Compactor Tools by Ferdinando Attanasio, Sergio Bortolini, Daniele Carbone, Andrea Pacifici

“…The proposed surgical procedure is minimally invasive, very simple, and fast and ensures good comfort for the patient by avoiding the elevation of mucoperiosteal flaps and uncomfortable malleting maneuvers. …”
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THE IMPACT OF MEDIA COVERAGE ON THE COURSE OF CRIMINAL PROCEEDINGS AND THE RIGHTS OF PARTICIPANTS by А.Ж. Муратова, И.С. Сактаганова, А.Б. Сактаганова, А.Е. Есеналиев, Р. Токанова

“…The purpose of the study is to analyze both legal and social aspects of interactions between media coverage and judicial system and make recommendations to minimize its negative influence. This work draws from a content analysis of media publications, comparative legal approach, and study of Kazakh and international judicial practice. …”
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Development of Real-Time Maneuver Library Generation Technique for Implementing Tactical Maneuvers of Fixed-Wing Aircraft by Do hyeon Lee, Chang-Joo Kim, Man Jung Heo, Joo Wan Hwang, Hee Gyeong Lyu, Jun Yeop Lee

“…The attitude command attitude hold (ACAH) system, the rate command rate hold (RCRH) system, and the speed command speed hold (SCSH) system using the proportional-integral-derivative (PID) control technique are designed to minimize the complexity of the flight control system (FCS) and to reduce the weight and volume of the payload. …”
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Acute Myeloid Leukemia Presenting as Myeloid Sarcoma with a Predisposition to the Gynecologic Tract by Ryan M. Kahn, Sushmita Gordhandas, Eloise Chapman-Davis, Elizabeth Margolskee, Cathleen Matrai, Amy Chadburn, Ellen Ritchie

“…MS of the gynecologic tract is exceedingly rare; however, it is hypothesized that it is likely more prevalent than previously understood given postmortem findings and persistence in preserved ovarian tissue. There is minimal literature surrounding MS and extramedullary relapse with no clear guidelines. …”
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From health inequalities to equitable health equality: ethical governance in healthcare empowers equity as social justice by Charles Biradzem Dine, Rondeau Dany

“…Thus, the objective of this research is to illustratively demonstrate an innovative healthcare intervention framework to subdue health inequalities amidst diversity, that is, how ethical governance in healthcare empowers equitable intervention against diversity with the impetus of social justice to minimize health inequalities and attain equitable health equality. …”
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A Cable-Passive Damper System for Sway and Skew Motion Control of a Crane Spreader by La Duc Viet, Youngjin Park

“…Moreover, the optimal damping coefficient can be found analytically by minimizing the time integral of system energy. The numerical simulations show that the proposed passive system can assist the input shaping control of the trolley motion in reducing both sway and skew responses.…”
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Optimization of Integrated Impeller Mixer via Radiotracer Experiments by N. Othman, S. K. Kamarudin, M. S. Takriff, M. I. Rosli, E. M. F. Engku Chik, M. A. K. Adnan

“…Thus, in this study, a 4-factor 3-level Taguchi L9 orthogonal array was introduced to obtain an accurate optimization of mixing efficiency with minimal number of experiments. This paper describes the optimal conditions of four process parameters, namely, impeller speed, impeller clearance, type of impeller, and sampling time, in obtaining MRT and Vdead (%) using radiotracer experiments. …”
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Model Predictive Control for Load Frequency Control with Wind Turbines by Yi Zhang, Xiangjie Liu, Yujia Yan

“…The proposed algorithm solves a series of local optimization problems to minimize a performance objective for each control area. …”
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Solution processable perovskite-hybrid heterojunction silicon 4T tandem solar cells by Mohammad Adil Afroz, Bhavna Sharma, Ruchi K. Sharma, Ritesh Kumar Gupta, Ankita Sengupta, Sanjay K. Srivastava, Soumitra Satapathi

“…The proposed 4-terminal tandem architecture exploits light management through the bandgap matching of the perovskite cell with silicon to minimize thermalization and absorption losses. This has led to a significant 41 % enhancement in the PCE of the HHSC. …”
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Multi-Objective Genetic Algorithm for Task Assignment on Heterogeneous Nodes by Carolina Blanch Perez del Notario, Rogier Baert, Maja D'Hondt

“…Specifically, we maximize task execution quality while minimizing energy and bandwidth consumption. Moreover, in our video processing scenario; we consider transcoding to lower spatial/temporal resolutions to tradeoff between video quality; processing, and bandwidth demands. …”
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Effect of Annealing on Microstructure and Mechanical Properties of Magnetron Sputtered Cu Thin Films by Shiwen Du, Yongtang Li

“…The surface morphology, roughness, and grain size of the Cu films were characterized by AFM. The minimization of energy including surface energy, interface energy, and strain energy (elastic strain energy and plastic strain energy) controlled the microstructural evolution. …”
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