Efficacy of Olmesartan/Amlodipine Single‐Pill Combination on 24‐h Mean Systolic Blood Pressure Measured by Ambulatory Monitoring in Non‐Responders to Valsartan or Candesartan Monot... by Woo‐Baek Chung, Sang‐Hyun Ihm, Yun‐Seok Choi, Ho‐Joong Youn

“…Isolated systolic hypertension (ISH) is the most prevalent form of hypertension in middle‐aged and elderly individuals. Patients aged over 55 years who did not achieve the target systolic blood pressure (SBP < 140 mmHg) with valsartan 80 mg or candesartan 8 mg for at least 4 weeks were included. …”
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A Digital Behavior Change Intervention for Health Promotion for Adults in Midlife: Protocol for a Multidimensional Assessment Study by Dagmar Soleymani, Dominique Pougheon-Bertrand, Rémi Gagnayre

“… BackgroundTo support lifelong health promotion and disease prevention, Santé publique France studied the methodology for building a social marketing scheme with a digital intervention targeting middle-aged adults, specifically socioeconomically disadvantaged groups. …”
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Walking for transport and all-cause mortality: a prospective cohort study of Australian community-dwelling older adults by Rory Wolfe, Neville Owen, Ben Beck, Yang Chen, David W Dunstan, Alice Owen, Robyn L Woods, Danijela Gasevic, Joanne Ryan, Shivangi Shah, Carlene Britt

“…Background Walking for transport may prolong survival in younger and middle-aged adults; however, evidence for older adults is scarce. …”
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Time-series forest age estimation in Xinjiang based on forest disturbance and recovery detection by Lili Zhai, Mei Zan, Mao Ye, Jia Zhou, Cong Xue, Shunfa Yang, Yuntong Liu

“…From 1992 to 2022, Xinjiang experienced a net increase in forest area of 28580.69 km2; (3) the forest age distribution from 1991 to 2022 indicates a predominance of young and middle-aged forests, with the proportion of old forests remaining between 30 % and 40 %, showing a gradual annual increase. …”
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Characteristics, clinical manifestations and management of leprosy in KwaZulu-Natal, South Africa: A 20-year retrospective study by J S Sons, Z N Mkhize, N C Dlova, C Aldous, P R Bhat, A V Chateau

“…The majority of patients were male and middle aged, with a disproportionate representation of black South Africans. …”
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EVOLUTION OF THE PHENOMENON OF CITIZENSHIP IN THE CONTEXT OF HISTORICAL DEVELOPMENT OF THE WESTERN EUROPE by L. Y. Maximova

“…As a result, Roman citizenship was unified, that led to the formation of the legal status of “subject of the Roman Empire,” for which no longer required property and which did not involve political participation. In the Middle Ages and Early Modern Period, for which characteristic subjection and vassalage was a type of relationship between the supreme power and the population, the phenomenon of citizenship existed only in cities. …”
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Therapeutic alliance impact on analgesic outcomes in a real-world clinical setting: An observational study by Barrachina Jordi, Margarit César, Andreu Blanca, Zandonai Thomas, Ballester Pura, Muriel Javier, Cutillas Esperanza, Peiró Ana M.

“…Patients were predominantly middle-aged (75 % women, 72 % retired), experiencing moderate pain (VAS 40–70 mm) on average, and under a high morphine equianalgesic dosage (95 ± 88 mg per day, mainly tapentadol or fentanyl). …”
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Association of lung health and cardiovascular health (Life’s Essential 8) by Wanjia Zhang, Menglong Zou, Junyao Liang, Dexu Zhang, Man Zhou, Hui Feng, Chusen Tang, Jie Xiao, Zhan Yi, Yin Xu

“…Regarding lung function, each 10-point increase in LE8 was associated with an increase of 50 ml in FEV1 (Beta = 50; 95% CI = 32, 67) and 56 ml in FVC (Beta = 56; 95% CI = 32, 79). Among middle-aged and older adults (age &gt; 40), the high LE8 group had significantly lower odds of respiratory symptoms, including cough (OR = 0.23; 95% CI = 0.12, 0.46), phlegm (OR = 0.42; 95% CI = 0.19, 0.90), and wheezing (OR = 0.29; 95% CI = 0.15, 0.54). …”
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Evaluation of the Therapeutic Effect of Traditional Chinese Medicine on Osteoarthritis: A Systematic Review and Meta-Analysis by Lin Wang, Xiao-Fei Zhang, Xue Zhang, Dong-Yan Guo, Yu-Wei Duan, Zhi-Chao Wang, Li-Shan Pei, Han Ru, Jiang-Xue Cheng, Ya-Jun Shi, Jun-Bo Zou

“…Osteoarthritis (OA) is a common degenerative disease of bone and joint characterized by the damage of articular cartilage and hypertonia, which often occurs in the middle-aged and elderly. Traditional Chinese medicine (TCM) therapy, including acupuncture (ACU), oral administration, and external use of traditional Chinese medicines (TCMs), can significantly improve the therapeutic effect on OA and reduce the occurrence of side effects. …”
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A cohort study of serum 25-hydroxyvitamin D levels and the risk of hyperlipidaemia in adults by Zi-yue Liu, Sha Liu, Xue Yao, Chun-yang Wang, Yunhao Song, Yan-ming Bi, Jin-Xiu Wang, Yang Li, Ta-la Shi, Wei Mi, Caiyun Chen, Zhi-Yong Hu

“…Vitamin D deficiency and insufficiency were prevalent among the middle-aged and elderly population (78.24%). Significant differences were found between the two groups in multiple sociodemographic variables, behavioral factors, and metabolic risk factors (p &lt; 0.05). …”
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The Potential Role of sPD-L1 as a Predictive Biomarker in EGFR-Positive Non-Small-Cell Lung Cancer by Vesna Ćeriman Krstić, Dragana Jovanović, Natalija Samardžić, Milija Gajić, Jelena Kotur Stevuljević, Aleksandra Klisic, Ivan Soldatović, Damir Radončić, Marina Roksandić Milenković, Biljana Šeha, Nikola Čolić, Katarina Lukić, Milan Savić

“…We analyzed sPD-L1 concentrations in 30 healthy middle-aged subjects, as a control population, to determine the reference range. …”
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Short-Term Effect of Air Pollution on Daily Hospital Visits for Anxiety Disorders in Southern China with Low Pollution Concentrations by Xinyuan Zhong, Tingting Guo, Jianghui Zhang, Qiong Wang, Rong Yin, Kunpeng Wu, Qing Zou, Meng Zheng, Brian J. Hall, Andre M. N. Renzaho, Kangning Huang, Wen Chen

“…The effects of NO₂ and CO remained robust across subgroup analyses and sensitivity analyses. Females and middle-aged individuals showed stronger associations than other subgroups. …”
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Le port antique de Chelles (Seine-et-Marne) : une course après la rivière by Yann Le Jeune, Corinne Charamond, Christian Charamond

“…The dating of the displacement is yet to be specified, but would appear to be later than or contemporary to the Roman period and was already in place in the Middle Ages.…”
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Assessment of Asthma Control and Quality of Life among Asthmatic Patients Attending Armed Forces Referral and Teaching Hospital, Addis Ababa, Ethiopia by Tesfalidet Gebremeskel Zeru, Ephrem Engidawork, Alemseged Beyene Berha

“…Uncontrolled asthma was associated with middle-aged adults (adjusted odds ratio AOR=6.31; 95% CI: 2.06, 19.3; P=0.001), male gender (AOR=0.38; 95% CI: 0.15, 0.98; P=0.044), married (AOR=0.24; 95% CI: 0.08, 0.78; P=0.017), comorbidities (AOR=0.23; 95% CI: 0.09, 0.61; P=0.003), and oral SABA use (AOR=0.22; 95% CI: 0.09, 0.59; P=0.003). …”
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Země Koruny české a Svatá říše římská v raném novověku by Petr Vorel

“…It was not until the turn of the 17th and 18th centuries, when the Habsburgs' diplomacy strove to enhance its influence among the Electors at the Imperial Diet (which was crowned with success in 1708), that we can see the special-purpose historical interpretation stating that the affiliation of the Bohemian Lands to the Empire had never been interrupted from the Middle Ages and the absence of the King of Bohemia at the Electors' sessions was explained as a consequence of the fact the king also held the office of the emperor. …”
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Les zones de production du fer en Bourgogne-Franche-Comté : une approche sur la longue durée par le radiocarbone by Marion Berranger, Marc Leroy, Hervé Laurent

“…They were, however, active again during the early Middle Ages and other areas that had not previously existed appeared in the data (Morvan-Auxois, Mâconnais, the Berthelange area). …”
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Path model explaining the association between fear of falling and health-related quality of life in (pre-)frail older adults by Tjard Sattler, Sophie Gottschalk, Hans-Helmut König, Tobias Braun, Gisela Büchele, Michael Denkinger, Tim Fleiner, Corinna Nerz, Kilian Rapp, Martina Schäufele, Christian Werner, Judith Dams

“…The model included potential explanatory pathways through physical activity (German Physical Activity Questionnaire for middle-aged and older adults), physical capacity (Short Physical Performance Battery), physical performance (Late-Life Function and Disability Instrument [LLFDI] function component), disability (LLFDI disability component – short form), and affect (visual analogue scales on ‘happiness’, ‘sadness’, ‘calmness’ and ‘tension’). …”
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Socio-economic assessment of drought impacts in Lesotho: implications for early action by Relebohile Agnes Mojaki, Makoala Vitalis Marake, Evan Easton-Calabria, Joalane Rethabile Marunye, Erin Coughlan de Perez

“…Overall, this paper conducted 48 community consultations where genderized focus group discussions (mixed elderly, mixed youth, middled aged men and women) and nine key informants (local authorities, schoolteachers, wisemen and women in the community) interviews were conducted. …”
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Balneotherapy for the treatment of post-COVID syndrome: a randomized controlled trial by Diana Ovejero, Anna Ribes, Judit Villar-García, Marta Trenchs-Rodriguez, Daniel Lopez, Xavier Nogués, Robert Güerri-Fernandez, Natalia Garcia-Giralt

“…The majority of participants were middle-aged women (> 84%; mean age 48 years), and the most prevalent symptoms were fatigue, musculoskeletal pain, and neurocognitive impairment (> 88%). …”
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L’infanticide féminin en question chez les Gaulois du Midi : l’apport des analyses ADN sur les nouveau-nés enterrés dans les habitats de l’âge du Fer by Bernard Dedet, Henri Duday, Philippe Gruat, Mélanie Pruvost

“…It is also attested to by ancient texts, notably in Greece and Rome, as well as within the considered region during late Antiquity and the Middle Ages. It will of course be necessary to extend paleogenetic analyses to other assemblages of perinatal subjects to confirm or refute this hypothesis, and to determine whether this very particular “recruitment” according to sex is the result of a widespread phenomenon, whether from a geographical or chronological point of view, or whether it is specific to a few sites, perhaps related to a localized occurrence of economic or social crisis. …”
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