Choosing a starting professional trajectory: job-education mismatch effect by A. D. Melnik, A. E. Sudakova, N. L. Antonova

“…This information was further supplemented by semi-structured interviews with middle-aged workers conducted 7 to 10 years after graduation (n = 10) and by monitoring the effectiveness of Russian universities based on the number of enterprises serving as practical training bases under agreements established with universities from 2020 to 2022. …”
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A comparative analysis of global and Chinese trends in the burden of kidney cancer from 1990 to 2021 by Zhongli Qiao, Jun Xiong, Shenyu Zhang, Lin Chen, Jialin Wang, Runze Chen

“…Additionally, the age-standardized rate of kidney cancer in males was notably higher than in females, particularly among middle-aged males. The (1-MIR) of renal cancer increased from 0.36 to 0.62 in China and from 0.49 to 0.58 globally. …”
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Systemic nitric oxide metabolites and the chance of pre-diabetes regression to normoglycemia: A 9-year cohort study by Zahra Bahadoran, Parvin Mirmiran, Fereidoun Azizi, Asghar Ghasemi

“…Methods: This cohort study included 541 middle-aged Iranian men and women with Pre-DM, recruited in 2006-2008 and followed up to 2015-2017. …”
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Global, regional, and national burden of ischemic heart disease attributable to secondhand smoke from 1990 to 2019 by Xinyue Yang, Zhiqiang Zhang, Jiayi Sun, Wenjuan Zhang

“…Despite a declining trend in ASMR and ASDR, regional disparities persist. The elderly and middle-aged populations bore the most significant burden. …”
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The manor estate economy ofthe Republic of Two Nations (the Polish-Lithuanian Commonwealth) in the 16th-18th centuries from the Marxist and neo-institutionalist perspectives by Darius Žiemelis

“…Arguments are put forward for the thesis that the manor economy of the 16th-18th centuries in the RTN, affected by Western Europe's developing capitalist relationships, can be qualified neither as a typical feudal economy (which the Western European manor of the Middle Ages should properly be considered) nor as a typical capitalist enterprise. …”
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Sarcomatous tumor with external iliac vein aneurysm: a rare entity by Tushar Kalekar, Neeha Amit Jhala, Reetika Kapoor, Eshan Chetan Durgi, Karishma Krishnani

“…Case presentation A middle-aged male in his fifties presented to the emergency department with continuous bleeding from a wound over a right inguinal swelling that had been ongoing for four hours. …”
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IUENNA – openIng the soUthErn jauNtal as a micro-regioN for future Archaeology: A «para-description» by Hagmann, Dominik, Reiner, Franziska

“…This landscape spans from prehistoric times to the early Middle Ages and encapsulates the diverse Jauntal Valley. …”
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HISTORICAL-PHILOSOPHICAL-LEGAL RESEARCH OF THE PHENOMENON OF THE GENDER AS THE FACTOR OF THE SOCIAL STATUS OF THE UKRAINIAN WOMAN by H. F. Moskalyk, M. Y. Baranovska, M. O. Bulach

“…This trend found its continuation in the Roman Empire, significantly increased in the Middle Ages and left an imprint in the philosophy of modern times and German classical philosophy. …”
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Atherogenic index of plasma and cardiovascular disease risk in cardiovascular-kidney-metabolic syndrome stage 1 to 3: a longitudinal study by Yu Zhang, Yue Song, Yinfei Lu, Tao Liu, Ping Yin

“…Restricted cubic spline regression indicated the relationship between cumulative AIP and CVD risk is linear (P for nonlinear = 0.3377).ConclusionsIn middle-aged and elderly individuals with CKM syndrome, higher cumulative AIP and poorer AIP control were associated with an elevated incidence of CVD. …”
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Gender characteristics, social determinants, and seasonal patterns of malaria incidence, relapse, and mortality in Sistan and Baluchistan province and other province of Iran: A sys... by Maryam Khazaee-Pool, Mahmood Moosazadeh, Mehran Asadi-Aliabadi, Fereshteh Yazdani, Koen Ponnet

“…The findings highlight the need for health care and the importance of targeted malaria control interventions, especially for men, rural areas, hot weather conditions, and young to middle-aged age groups, particularly in the S&B province.…”
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A preliminary study on the reference intervals of vitamin K in some areas of Beijing with normal physical examination population by Lin Chen, Meiqi Chen, Shi Cheng, Jiaxin Fei, Dan Xu, Xueyun Hou, Nannan Li, Yuliang Yuan, Guijian Liu, Cheng An

“…Finally, preliminary clinical validation was conducted on 60 apparent healthy individuals undergoing physical examination. In the young, middle-aged, and elderly groups, the reference intervals of VK1 were 0.180 ng/mL ∼ 1.494 ng/mL, 0.247 ng/mL ∼ 1.446 ng/mL, and 0.167 ng/mL ∼ 1.445 ng/mL, respectively. …”
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Associations between oxidation balance score and abdominal aortic calcification, and the mediating role of glycohemoglobin: a nationally representative cross-sectional study from N... by Heqian Liu, Yifei Wu, Zhenyu Liu, Hongzhi Ren, Ya Wu, Ya Wu, Yong Liu, Yong Liu, Yong Liu

“…BackgroundAbdominal aortic calcification (AAC) is prevalent among middle-aged and elderly populations, elevating the risk of cardiovascular and cerebrovascular events. …”
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The association between hair cortisol and burnout is moderated by age, psychosocial, and immunological markers by Patrick D. Gajewski, Peter Bröde, Maren Claus, Klaus Golka, Jan G. Hengstler, Carsten Watzl, Edmund Wascher, Stephan Getzmann

“…These interactions were moderated by age showing the largest impact in middle-aged to older individuals. Conclusions: The present findings shed light on the complex interaction between burnout symptoms and work ability, chronic stress, personality, and the endocrinological and immunological responses across the working lifespan. …”
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Changes in Alcohol Consumption During and After the Covid-19 Pandemic From 2020 to 2023 in a Prospective Cohort of Italian Adults by Sonia Cerrai, Giulia Carreras, Filippo Monti, Chiara Stival, Alessandra Lugo, Cristina Bosetti, Silvia Biagioni, Tiziana Fanucchi, Giuseppe Gorini, Andrea Amerio, Luisa Mastrobattista, Claudia Mortali, Anna Odone, Sabrina Molinaro, Luc Smits, Silvano Gallus, the “Lost in Italy” and “Lost in Toscana” Study Investigators

“…Being at-risk alcohol consumers decreased with decreasing economic status (P for trend <0.001), was less frequent among middle-aged compared to younger (OR 0.73; 95% CI, 0.60–0.89) and among divorced/separated (OR 0.77; 95% CI, 0.60–0.99) or single (OR 0.75; 95% CI, 0.64–0.89) compared to married individuals. …”
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Association between red cell distribution width—albumin ratio and all-cause mortality in intensive care unit patients with heart failure by Ni Li, Junling Li, Kai Wang

“…Subsequent analysis revealed that the inclusion of RAR significantly improved the prognostic value on the basis of SOFA and APACHE Ⅱ, and the concordance index increased from 0.636 to 0.658 for SOFA, from 0.682 to 0.695 for APACHE Ⅱ (p &lt; 0.001 for both).ConclusionThe study found that high level of RAR was independently associated with an increased risk of 1-year all-cause mortality in ICU patients with heart failure, with a stronger effect in young and middle-aged patients and a threshold effect, which could potentially serve as an early warning indicator for high-risk populations.…”
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Gender-specific dual effects of physical activity on depression and mortality: a nine-year cohort study in Chinese adults aged 45 and above by Dan Shan, Dan Shan, Meina Yang, Meina Yang, Kunyan Zhou, Kunyan Zhou

“…Specific relationships between PA, depression, and mortality were then investigated by applying multivariate logistic regression and Cox proportional hazards models.ResultsHighest quantile levels of PA were correlated with a 37% increase in the risk of new-onset depression in middle-aged (45–59 years) and older adults (&gt;60 years). …”
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Clinical and endoscopical and morphofunctional scores in evaluation of development of gastroesophageal reflux disease in various age groups by M. A. Osadchuk, A. M. Zolotovitskaya, N. V. Kireyeva, S. N. Nikolenko, I. M. Kvetnoy

“…The catarrhal form of GERD at middle-aged patients develops on a background of gastritis with signs of atrophy, associated to H. pylori infection, contaminations of distal esophagus by H. pylori and foci of gastric metaplasia, dysfunction of motility of upper regions of the gut on a background of hyperplasia of NO-synthase and endothelin-1-producing cells of the esophagus and the stomach. …”
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Fatigue in living kidney donors compared to a German general population sample: an exploratory study by Dilek Akkus, Adrian Westenberger, Gunilla Einecke, Gunilla Einecke, Wilfried Gwinner, Uwe Tegtbur, Mariel Nöhre, Martina de Zwaan

“…However, higher fatigue in donors was associated with more donation regret, a more negative relationship with the recipient, a more negatively perceived recipient health, less perceived family support, and more financial burden.ConclusionFatigue is less prevalent particularly in older donors and predictors of fatigue presented in the general population sample seem to have little importance in the donors. However, middle-aged female donors might be more prone to develop fatigue. …”
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Age-stratified analysis of the BMI-kidney stone relationship: findings from a national cross-sectional study by Liuliu Zhou, Wei Gu, Yufeng Jiang, Haimin Zhang

“…This non-linear relationship suggests that the impact of BMI on kidney stone risk varies by age and should be considered in clinical strategies.ConclusionHigh BMI is significantly associated with an increased risk of kidney stones, particularly among middle-aged and older adults. The relationship between BMI and kidney stones is non-linear, highlighting the need to develop age-specific BMI management strategies to reduce the occurrence of kidney stones.…”
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Carbon sequestration effects of the typical restored vegetation types in Eastern Qinling Mountains by XU Xiaoming, YAN Shanshan, PENG Xiaobang

“…The carbon density of forest ecosystems was higher in the middle- aged forest stage and near-mature forest stage. …”
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