The Effect of P-Cymene on Glucose, Insulin, Antioxidant Power, and the Level of AKT Gene mRNA in Streptozotocin-Induced Diabetes Model in Male Wistar Rats by Maryam Arabloei Sani, Zahra Hajebrahimi, Parichehreh Yaghmaei, Nasim Hayati Roodbari

“…Background and Aim: Diabetes is a main metabolic disorder in middle-aged and older people. Oxidative stress can interfere with insulin signaling and are directly relevant to the incidence of diabetes. …”
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THE CULTURAL AND RELIGIOUS DIMENSION OF THE FOREIGN POLICY OF RUSSIA AT THE TURN OF 17TH AND 18TH CENTURIES by A. V. Skizhenok

“…The author of this article aims to examine the role and place of the Russian Orthodox Church in Russia's transition from the regional state of the Middle Ages to an absolutist state of Modern history. …”
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Female Farmers’ Agricultural Information Needs and Food Production: A Case Study of Imbulpe ds Division in Sri Lanka by S.D. Dilini Rathnachandra, S.H. Pushpa Malkanthi

“…The result revealed that the majority (62.6%) of respondents were middle aged (40-59 years), married, and belonged to families with 4-5 members. …”
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Historiography in Vilnius University from 1803 to 1832: between education and romanticizm by Mečislovas Jučas

“…Lelevel divided universal history into the following epochs: Ancient Orient, Roman and Greek, and the Middle Ages (VI-XV). He stressed Christianization and feudalization (of different Western and Eastern models), and, in the New Ages (XVI-XIX century), absolutism and revolutions. …”
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Health economics assessment of statin therapy initiation thresholds for atherosclerosis prevention in China: a cost-effectiveness analysis by Tianyu Feng, Xiaolin Zhang, Jiaying Xu, Shang Gao, Xihe Yu

“…The model utilized the China-PAR prediction tool for ASCVD risk and incorporated data from a nationally representative survey and published meta-analyses of middle-aged and elderly Chinese populations. Four strategies were evaluated: a 7.5% 10-year risk threshold, the current guideline strategy, and a 15% threshold. …”
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SOCIO-ECONOMIC CONSEQUENCES OF IMMIGRATION IN ITALY by E. J. Tsareva

“…The increasing number of migrants has created a certain imbalance in different spheres of life and society. The middle-aged population in Italy is ever growing, thus migrants play an important role in filling the workforce depletion as well as flooding the labor market. …”
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Diagnosis and Management of Acquired Hemophilia A: Case Reports and a Literature Review by Ikhwan Rinaldi, Findy Prasetyawaty, Siti Fazlines, Kevin Winston, Yusuf Aji Samudera Nurrobi, Jessica Leoni, Ilham Hidayat Restu Tulus Maha, Satrio Wicaksono, Abdillah Yasir Wicaksono, Averina Octaxena Aslani, Rizkania Ikhsani

“…The first patient was a young female, while the second and third patients were middle-aged and elderly males, respectively. All patients presented with a chief complaint of bruises without hemarthrosis and a history of bleeding. …”
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Auditory steady state response can predict declining EF in healthy elderly individuals by Xiaopeng Mao, Xiaopeng Mao, Nelly Shenton, Sadasivan Puthusserypady, Martin Johannes Lauritzen, Krisztina Benedek

“…The ViTs trained and cross-validated on time-frequency-transformed Electroencephalograms (EEGs) achieved an average cross-subject accuracy of 51.8% in identifying cognitive decline.ConclusionGamma-band ASSR characteristics are linked to early cognitive decline in middle-aged individuals, offering potential as biomarkers. …”
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Medieval Overexploitation of Peat Triggered Large-Scale Drowning and Permanent Land Loss in Coastal North Frisia (Wadden Sea Region, Germany) by Hanna Hadler, Antonia Reiß, Timo Willershäuser, Dennis Wilken, Ruth Blankenfeldt, Bente Majchczack, Stefanie Klooß, Ulf Ickerodt, Andreas Vött

“…Along the southern North Sea coast from the Netherlands to Denmark, human cultivation efforts have created a unique cultural landscape. Since the Middle Ages, these interactions between humans and natural forces have induced major coastal changes. …”
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Impact of Mediterranean Diet Adherence on the Incidence of New‐Onset Hypertension in Adults With Obesity in Korea: A Nationwide Cohort Study by Jung‐Hwan Kim, Ji‐Won Lee, Yaeji Lee, Chung‐Mo Nam, Yu‐Jin Kwon

“…ABSTRACT This study investigated the association between adherence to the Mediterranean diet (MD) and new‐onset hypertension (HTN) in a cohort of community‐dwelling, middle‐aged, older Korean individuals with obesity. …”
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Long-Term Intracranial Progression-Free Survival in Lung Cancer Brain Metastases Extended Beyond 50 Months with Gubenxiaoyi Formula (GBXY): A Groundbreaking Case Study by Zhengzheng Yang, Haiming Li, Lei Chen, Shujiao Li, Dong Chen, Taicheng Lu, Tongjing Ding, Ruiyang Han, Peiyu Cheng, Xiaomin Wang

“…Case presentation Here, we present a case of a middle-aged female with lung cancer BM, whose condition was assessed as progressive post-standard treatment including two local surgeries (both involving resection of cerebellar space-occupying lesions), stereotactic radiotherapy, chemotherapy and EGFR-TKIs. …”
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What a women desire: Application of conjoint analysis for analysing the choice of menstrual hygiene products and factors influencing their consummatory behaviour by Tiwari Abhay Kumar, Patel Vaishali, Saroj Chitra

“…Background/Aim: Middle-aged adolescent girls and women experience menstruation, a normal and physiologic occurrence. …”
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A Multimodal Approach to Analgesia in Anorectal Surgery by T. N. Garmanova, D. R. Markaryan, E. A. Kazachenko, A. M. Lukianov, M. A. Kazachenko, M. A. Agapov

“…Mainly anorectal disorders affect middle-aged people reducing their life quality. At the same time many articles aimed at studying only postoperative anesthesia. 2 researchers independently searched for articles published in Medline, Scopus, Cochrane, Web of Science, E-library databases using keywords. …”
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Efficacy of Neoadjuvant Chemotherapy DOX and XELOX Regimens for Patients with Resectable Gastric or Gastroesophageal Junction Adenocarcinoma by Yuan Tian, Qun Zhao, Yong Li, Liqiao Fan, Zhidong Zhang, Xuefeng Zhao, Bibo Tan, Dong Wang, Peigang Yang

“…Neoadjuvant DOX is an effective and feasible regimen and might represent an option for young and middle-aged patients with locally advanced, resectable gastric or gastroesophageal junction adenocarcinoma.…”
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Diverse clinical manifestations and prognosis in a couple’s mercury poisoning caused by skin-lightening creams: two case reports and literature review by Huixia Ji, Ye Chen, Dandan Liu, Tongzhou Zhou, Yuhua Tang

“…Skin exposure to mercury-containing creams occurs most commonly in young and middle-aged women and, in a few cases, in men. This article presents the symptoms and prognosis of a couple who developed mercury poisoning after cosmetic use of similar duration and dosage. …”
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The Unforeseen Diagnosis: Hyperparathyroidism-Jaw Tumour Syndrome Case Report and Review of the Literature by Maxim Barnett, Farhan Ahmed, Radu Mihai, Asha Rattan, Malik Asif Humayun

“…Primary hyperparathyroidism, a frequent cause of hypercalcaemia, is often seen among middle-aged female patients, typically resulting from an underlying single-gland adenoma. …”
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Risk of adverse cardiovascular events based on common genetic variants in 8-year follow-up of the LIPIDOGEN2015 population using the polygenic risk score (PRS): study design and me... by Maciej Banach, Martyna Fronczek, Tadeusz Osadnik, Agnieszka Gach, Dominik Strapagiel, Marcin Słomka, Mateusz Lejawa, Anna Goc, Ewa Boniewska-Bernacka, Anna Pańczyszyn, Gregory Y.H. Lip, Dimitri P. Mikhailidis, Peter P. Toth, Peter E. Penson, Jacek Jóźwiak

“…Polygenic risk scores (PRS) can be effective in predicting adverse coronary events in younger and middle-aged patients. Our main aim is to assess the utility of a new PRS created for the Polish population in predicting mortality during an 8-year follow-up in the nationwide LIPIDOGEN2015 population. …”
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Clinical Characteristics and Visual Outcomes of Patients Hospitalized for Ocular Trauma in Shandong Province, China by Fangnan Duan, Xiunian Chen, Sai Zhang, Xiaolin Qi, Weiyun Shi, Hua Gao

“…Ocular trauma usually occurs in young and middle-aged men and in the workplace in Shandong Province. …”
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Disparity of serum uric acid threshold for CKD among hypertensive and non-hypertensive individuals by Bowen Zhu, Fang Li, Weidong Zhang, Shuan Zhao, Nana Song, Shi Jin, Ziyan Shen, Yufei Lu, Yang Li, Hong Liu

“…In the propensity score matched (PSM) population, the result remained roughly constant.Conclusion Therefore, even moderate levels of sUA was associated with a higher risk of CKD in middle-aged hypertensive patients, who warrant stricter sUA control.…”
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Global burden of osteoarthritis from 1990 to 2019 attributable to high body mass index by Siming Yang, Licheng Zhou, Wanchen Gong, Bin Guo, Linfeng Wang

“…In particular, this burden was higher in women than in men; primarily affected middle-aged and older adults; and was generally greater in high-SDI regions than in low-SDI regions.…”
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