Mixoid Liposarcoma by Azamris Azamris, Peri Handayani, Muhammad Rifki

“…Liposarcoma is malignant tumor or cancer at fatty tissue, characterized by abortif differentiated cells to lipocyte and the common type of soft tissue sarcoma, appearing slowly, enlarged, painless, nonulceratif mass submucosal at the middle age. If the early detected the cure rate can be better. …”
Get full text

Expression Profile of Brain Aging and Metabolic Function are Altered by Resveratrol or α-Ketoglutarate Supplementation in Rats Fed a High-Fat Diet by Paulina Szczurek-Janicka, Katarzyna Ropka-Molik, Maria Oczkowicz, Sylwia Orczewska-Dudek, Mariusz Pietras, Marek Pieszka

“…The aim of this study was to examine the impact of different dietary interventions started at middle age on the metabolic phenotype and gene expression profiling in the hypothalamus. …”
Get full text

The effect of a barley-based food product in alleviating knee osteoarthritis discomfort symptoms in Egyptian female patients by Suzanne Fouad, Rasha Monir, Fatma A. Ibrahim, Ahmed M.S. Hussein, Heba F. Shafei, Aliaa El Gendy

“…Patients and methods The present study enrolled 51 Egyptian middle age females patients with a mean age of 51±8.37 years, diagnosed with bilateral grade two to three knee osteoarthritis were recruited from the National Research Centre rheumatology and rehabilitation clinic. …”
Get full text

Educating patients about health helps slow the progression of chronic kidney disease in the eastern region of India by Supriya Dasgupta, Reeti Debnath

“…Results: In this study, several factors were linked to elevated creatinine levels among CKD patients, including being in the middle-age range, male gender, living predominantly in urban areas, and working in business or service occupations. …”
Get full text

Cardiometabolic deaths in black and white men: Tracing the risks from early- to mid-adulthood by Rebecca Arden Harris, Sameed Ahmed M. Khatana, Judith A. Long

“…Black and White men during the transition from early adulthood to middle age. Methods: Using 2022 National Vital Statistics System data and standard period life table methods, we estimated the risk of CMD death in hypothetical cohorts of Black and White men from age 25 to 45 years. …”
Get full text

A comprehensive analysis of percutaneous liver biopsy characteristics and pathological manifestations in a large patient cohort (2009–2024) by Minling Cao, Jiayi Zeng, Jiayu Wang, Junmin Jiang

“…Patients with hepatitis B complicated by MASLD exhibited disease exacerbation in middle age, with both liver inflammation and fibrosis grading worsening as age advanced. …”
Get full text

Assessing the Relationship Between the Type of Internet Use and Internet Addiction in Early and Middle Adolescents: Cross-Sectional Study From Qatar by Khansa Chemnad, Maryam Aziz, Sanaa Al- Harahsheh, Azza Abdelmoneium, Ahmed Baghdady, Diana Alsayed Hassan, Raian Ali

“…To explore age-specific associations, participants were categorized into early (age 11-13 years) and middle (age 14-17 years) adolescents. Factorial analysis, multiple regression, and logistic regression were used for statistical analysis. …”
Get full text

GDF11 restores the impaired function of EPCs-MA by promoting autophagy: GDF11 ameliorates endothelial progenitor cell aging by promoting autophagy by Liu Donghua, Zhang Yang, Liu Xin, Huang Qihe, Zhang Xiaofang, Yang Rui, Zhao Yue, Li Penghui, He Jiayi, Zhang Kexiao, Pan Zhenwei, Liu Huiwen, Yang Baofeng

“…Our study aimed to assess the effects of Growth and differentiation factor 11 (GDF11) on the function of endothelial progenitor cells in middle-age individuals (EPCs-MA) isolated from mouse bone marrow and to explore the mechanistic relationship between GDF11 and age-related ALP impairment.…”
Get full text

Relation of Follicular Fluid Soluble Receptor for Advanced Glycation End-Products Concentration and Anti Mullerian Hormone in Polycystic Ovary Syndrome and Non-PCOS Women Referring... by Neda Emami, Ashraf Moini, Samira Vesali

“…The results show that the levels of these receptors (sRAGE)show their specific effects in young women and women over 40 years old and not in middle age and target the ovarianreserve. It seems to act as a defensive shield in older women and increase fertility in young women.…”
Get full text

A Rare Case of Arteriovenous Hemangioma Clinically Mimicking Pigmented Nevus by Sri Lestari, Tofrizal ., Yenny Raflis

“…Arteriovenous hemangioma is a tumor of middle-age to elderly adults with a peak incidence in the fourth and fifth decades of life. …”
Get full text

Association between spasticity and neuropathic pain in patients with multiple sclerosis by B. Afanasjeva, R. Balnytė

“…The examined patients were diagnosed with MS at the middle age, the majority of subjects had the relapsing-remitting disease, and disability was higher in the patients with progressive forms. …”
Get full text

Body weight gain and development of reproductive tract in crossbred Murrah × Mediterranean water buffalo heifers by Oswaldo J. González, Amílcar Acuña, Solaine Bradley, Ysis Cañizalez, Jorge Espinoza, Cindy Paniagua, María Virginia Suárez, Mónica Fuentes

“…The buffalo heifers (middle age: 710 days old and middleweight: 237 Kg) were randomly assigned to one of two treatments for 174 days. …”
Get full text

What are parents' preferences for Human Papillomavirus vaccination promotion messages and communication? Application of a discrete choice experiment to a French Caribbean setting by Frédérique G. E. Dorleans, Jonathan Sicsic, Valérie Henry, Isabelle Bonmarin, Gwladys Nadia Gbaguidi, Lucie Leon, Jocelyn Raude, Jacques Rosine, Judith E. Mueller

“…Methods We conducted a cross-sectional survey in public and private middle age schools in Guadeloupe in June 2023 using an online questionnaire. …”
Get full text

Heatstroke characteristics and meteorological conditions in Hefei, China: thresholds and driving factors by Xueliang Deng, Liang Zhao, Changchun Xiao, Rui Dai, Qianqian Xu, Yeqing Yao, Caimeng Liang, Lei Yao, Dongyan He

“…The highest frequency of heatstroke occurrence was found to be concentrated in the middle age group (40–59 years old). According to the statistical analysis, air temperature and relative humidity were the most important meteorological factors that influenced the occurrence of heatstroke. …”
Get full text

Clinical Profile and Outcome in Patients with Coronary Slow Flow Phenomenon by Xiaogang Zhu, Hua Shen, Fei Gao, Sijing Wu, Qian Ma, Shuo Jia, Ziwei Zhao, Shan Tong, Zhihao Zhang, Yujie Zhou

“…CSFP affects predominantly patients at middle age and above but can occur in any age group; CSFP should be more concerned, particularly in patients >50 years old with hypertension and dyslipidemia.…”
Get full text

Validation Indicator Identification and Customer Ranking in Microloans: A Study at Middle East Bank in Iran by Azadeh Ahmadi Kousha, Faegh Ahmadi, Mohammad Hossein Ranjbar, Hamidreza Kordlouie

“…Fourth, the person's age is above middle age. Fifth, the person's degree is not a bachelor's degree, diploma, or sub-diploma. …”
Get full text

Age-related changes in brain signal variability in autism spectrum disorder by Priyanka Sigar, Nicholas Kathrein, Elijah Gragas, Lauren Kupis, Lucina Q. Uddin, Jason S. Nomi

“…The group × quadratic age interaction showed significant differences in the brain regions included in DMN, with an inverted U-shaped rMSSD-age relationship in ASD (higher rMSSD in younger individuals that slightly increased into middle age before decreasing) and a U-shaped rMSSD-age relationship in TD (higher rMSSD in younger and older individuals compared with middle-aged individuals). …”
Get full text

Age-related effects on dynamic postural stability and prefrontal cortex activation during precision fitting tasks by Jiahao Pan, Hui Tang

“…Additionally, the older group had greater PFC activation at all PFC subregions than the young group (p < .05), while had greater activation at left dorsolateral and ventrolateral PFC than the middle-aged group (p < .05). The middle-aged group presented greater activation at left dorsomedial PFC than the young group (p < .05). …”
Get full text

L’entreprise de Giotto by Daphné de Luca

“…The comparative study of several big wooden crosses painted by Giotto allowed to deepen the work organization in the Middle Ages’ workshop. This analysis found several analogies of execution between the works, by demonstrating that the production of these masterpieces was subordinated to certain codified rules, pre-established by the workshop’s master, a really skilful business manager of the Middle Ages.…”
Get full text

PHILOSOPHY OF CULTURE M.M. BAKHTIN: HISTORICAL AND ANTHROPOLOGICAL DIMENSION by Spartak Sh. Aytov

“…Bakhtin as a carnival, folk culture, culture of humor, doubleworld, concept social-cultural projection material and cultural bottom and its impact on the culture of laughter European Middle Ages and Renaissance. Methodological approaches Bakhtin recreated for historical and anthropological reconstruction mentality and socio-cultural realities of the high Middle Ages and the Renaissance. …”
Get full text