Improved Outcomes following the Establishment of a Neurocritical Care Unit in Saudi Arabia by Ibrahim Soliman, Waleed Tharwat Aletreby, Fahad Faqihi, Nasir Nasim Mahmood, Omar E. Ramadan, Ahmad Fouad Mady, Babar Kahlon, Abdulrahman Alharthy, Peter Brindley, Dimitrios Karakitsos

“…This is the first study in the Middle East to evaluate the clinical impact of a neurocritical care unit (NCCU) launched within the diverse clinical setting of a polyvalent intensive care unit (ICU). …”
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Harmful impacts of microplastic pollution on poultry and biodegradation techniques using microorganisms for consumer health protection: A review by Mohamed E. Abd El-Hack, Elwy A. Ashour, Fatemah AlMalki, Asmaa F. Khafaga, Mahmoud Moustafa, Mohammed O. Alshaharni, Islam M. Youssef, Ahmed A. Elolimy, Sylwester Świątkiewicz

“…Microplastics have been detected in various animal species, including poultry, fish, mammals, and invertebrates, indicating widespread exposure and potential bioaccumulation. In the Middle East, MPs contamination was discovered in chicken purchased from food shops, chain supermarkets, and open markets. …”
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Contextual adaptation of digital wellbeing interventions for young people: insights from a project in Saudi Arabia by Dahlia Aljuboori, Laura K. Clary, Saud Abdulaziz Alomairah, Saud Abdulaziz Alomairah, Michelle Colder Carras, Nazmus Saquib, Juliann Saquib, Fahad Albeyahi, Antonius J. Van Rooij, Anouk Tuijnman, Vincent G. Van der Rijst, Michelle R. Kaufman, Michelle R. Kaufman, Johannes Thrul, Johannes Thrul, Johannes Thrul

“…However, these interventions are lacking in the Middle East and North Africa, and specifically in Saudi Arabia, where digital media use is highly prevalent and frequent. …”
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Stability of compact stars in a uniform density background cloud by Ksh. Newton Singh, S. K. Maurya, A. Errehymy, O. Donmez, K. Myrzakulov, T. T. Smitha

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Patient experience and burden of haemolytic disease of the foetus and newborn: a systematic review by P. Maurice, J. McCallion, M. Fitzgibbon, J. N. Barthelmes, W. Karmous, E. J. Hardy, S. A. Mitchell, C. R. Mitchell, J. Lee, W. Noel, Andras Borsi, J. M. Jouannic

“…Methods Electronic database searches supplemented by handsearching of grey literature, were conducted to identify studies that reported the clinical patient burden/experience, and economic burden of HDFN in Europe, the Middle East, and Africa (EMEA). Data from eligible studies were summarised in a narrative synthesis due to heterogeneity between studies. …”
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Spectroscopic and Thermooxidative Analysis of Organic Okra Oil and Seeds from Abelmoschus esculentus by Geórgia de Sousa Ferreira Soares, Vinicius de Morais Gomes, Anderson dos Reis Albuquerque, Manoel Barbosa Dantas, Raul Rosenhain, Antônio Gouveia de Souza, Darlene Camati Persunh, Carlos Alberto de Almeida Gadelha, Maria José de Carvalho Costa, Tatiane Santi Gadelha

“…Similar to Okra varieties from the Middle East and Central America, Brazilian Okra has significant amounts of protein (22.14%), lipids (14.01%), and high amounts of unsaturated lipids (66.32%), especially the oleic (20.38%) and linoleic acids (44.48%). …”
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Waste heat recovery cycles integration into a net-Zero emission solar-thermal multi-generation system; Techno-economic analysis and ANN-MOPSO optimization by Pradeep Kumar Singh, Ali Basem, Rebwar Nasir Dara, Mohamed Shaban, Sarminah Samad, Raymond Ghandour, Ahmad Almadhor, Samah G. Babiker, Iskandar Shernazarov, Ibrahim A. Alsayer

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Phytochemical, Cytotoxic, and Antimicrobial Evaluation of the Fruits of Miswak Plant, Salvadora persica L. by Mohammed Al Bratty, Hafiz A. Makeen, Hassan A. Alhazmi, Sohier M. Syame, Ashraf N. Abdalla, Husham E. Homeida, Shahnaz Sultana, Waquar Ahsan, Asaad Khalid

“…(Salvadoraceae) is an evergreen shrub growing in the Middle East, Africa, and Southern Asia. It is traditionally known as “miswak” and used as toothbrushes and for the treatment of toothache, gum diseases, boils, chest infection, gonorrhea, headache, spleen troubles, stomachache, and ulcers. …”
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Conflict-associated wounds and burns infected with GLASS pathogens in the Eastern Mediterranean Region: A systematic review by Amelia Wild, Clare Shortall, Omar Dewachi, Carine Naim, Alex Green, Sarah Hussain, Aula Abbara

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Co-Optimization of Operational and Intelligent Completion Parameters of CO₂ Water-Alternating-Gas Injection Processes in Carbonate Reservoirs by Xili Deng, Jingxuan Wang, Xiangguo Zhao, Liangyu Rao, Yongbin Zhao, Xiaofei Sun

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Long COVID and its risk factors in migrants: a nationwide register study from Sweden by Agneta Cederström, George Frederick Mkoma, Thomas Benfield, Charles Agyemang, Marie Nørredam, Mikael Rostila

“…Compared with residents born in Sweden, we found higher risks of long COVID among migrants from East Europe (IRR: 1.44 CI: 1.29–1.60), Finland (IRR: 1.36 CI: 1.15–1.61), South Asia (IRR: 1.28 CI: 1.03–1.59), Other Asia (IRR: 1.35 CI: 1.13–1.62), Other Africa (IRR: 1.48 CI: 1.17–1.87), and the Middle East (IRR: 1.43 CI: 1.27–1.63) in models adjusted for age and sex. …”
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Modelling of structural, mechanical, electronic, and optical properties of Rb2TlXF6 (X = Ir, Rh) double perovskite compounds through density functional theory by Wasi Ullah, Nasir Rahman, Mudasser Husain, Wafa Mohammed Almalki, Khamael M. Abualnaja, Ghaida Alosaimi, Soufyane Belhachi, Bashar.M. Al-Khamiseh, Vineet Tirth, Ahmed Azzouz-Rached, Hanan A. Althobaiti, Farooq Ali

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Changes in Uterine Cancer Incidence Rates in Egypt by Saad Alshahrani, Amr S. Soliman, Ahmed Hablas, Mohamed Ramadan, Jane L. Meza, Steven Remmenga, Ibrahim A. Seifeldein, Robert M. Chamberlain

“…Egypt has significantly lower incidence of uterine cancer than other countries in the Middle East. This study aimed at verifying the incidence rate of uterine cancer and characterizing the demographic and clinical profiles of patients residing in the Gharbiah province in the Nile delta region of Egypt. …”
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Agronomic characteristics, mineral nutrient content, antioxidant capacity, biochemical composition, and fatty acid profile of Iranian pistachio (Pistacia vera L.) cultivars by Ali Khadivi, Mohammadali Nikoogoftar-Sedghi, Yazgan Tunç

“…The pistachio cultivars are tolerant to both drought and salinity, which is why they are extensively grown in the arid, saline, and hot regions of the Middle East, Mediterranean countries, and the United States. …”
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Traditional and Non-Traditional Risk Factors of Acute Coronary Syndrome in Young Women: Evidence from the ANCORS-YW Study by Ibdah R, Al-Nusair M, Abuhalimeh R, Mahmoud SA, Laswi B, Rawashdeh S, Hamoudeh A, Kheirallah KA

“…The current study aimed to describe traditional and non-traditional risk factors of ACS in young women from the Middle East.Patients and Methods: The present study used data from the Jordanian, nationwide, multicenter, case-control study, ANCORS-YW. …”
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Evaluation of musculoskeletal complaints, treatment approaches, and patient perceptions in family medicine clinics in a tertiary center in Jordan: a cross-sectional study by Moh’d S. Dawod, Mohammad N. Alswerki, Ahmad F. Alelaumi, Jehad Feras AlSamhori, Rana J. Rahhal, Lina Khraisat, Eman Mohammad Arabas, Hussein M. Bdair, Reem M. Alhyari, Mohammad Shahin, Mohammad Abu Hilal, Alaa Y. Akel, Aws Khanfar

“…Family medicine clinics serve as the first point of care, requiring providers to manage diverse MSK issues and address gender-specific differences, especially in regions with limited resources, like the Middle East. This study evaluates MSK management, gender differences, and patient perceptions in Jordanian family medicine clinics, aiming to improve care strategies and outcomes in similar settings. …”
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Fetal cardiac function in pregnancy affected by congenital heart disease: protocol for a multicentre prospective cohort study by Anna Erenbourg, Tracie Barber, Vera Cecotti, Stefano Faiola, Ilaria Fantasia, Tamara Stampaljia, Hagai Avnet, Beata Radzymińska-Chruściel, Neama Meriki, Alec Welsh

“…Methods A multicenter cohort study will be carried out in eight teaching hospitals across Europe, Australia, and Middle East. Based on a previous observed standard deviation, a total sample of 381 pregnancies is required to achieve 80% power to detect a difference of 0.03 in mean myocardial performance index (MPI) with a two-sided type I error rate of 5%. …”
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Absence of Standard Modifiable Risk Factors in Middle Eastern Patients with Atherosclerotic Cardiovascular Disease. The Jordan Absence of Standard Modifiable Risk Factors (SMuRF-Le... by Hammoudeh AJ, Aldalal’ah M, Smadi EA, Alrishoud D, Alomari A, Alkhawaldeh M, Rizik A, Okour MF, Araydah M

“…Prevalence of SMuRF-less patients in the Middle East has not been studied. This study investigates the prevalence, clinical profiles and outcomes of SMuRF-less patients compared with those who have SMuRFs.Methods: We analyzed data from 6 published registries and from the Jordan SMuRF-less patients study, including baseline demographic features, cardiovascular risk factors, comorbid diseases, utilization of secondary prevention pharmacotherapy and one year outcome in SMuRF-less patients, those with 1– 2 SMuRFs and with 3– 4 SMuRFs. …”
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29 m6A-RNA Methylation (Epitranscriptomic) Regulators Are Regulated in 41 Diseases including Atherosclerosis and Tumors Potentially via ROS Regulation – 102 Transcriptomic Dataset... by Ming Liu, Keman Xu, Fatma Saaoud, Ying Shao, Ruijing Zhang, Yifan Lu, Yu Sun, Charles Drummer, Li Li, Sheng Wu, Satya P. Kunapuli, Gerard J. Criner, Jianxin Sun, Huimin Shan, Xiaohua Jiang, Hong Wang, Xiaofeng Yang

“…We performed a database mining on 102 transcriptomic datasets for the expressions of 29 m6A-RNA methylation (epitranscriptomic) regulators (m6A-RMRs) in 41 diseases and cancers and made significant findings: (1) a few m6A-RMRs were upregulated; and most m6A-RMRs were downregulated in sepsis, acute respiratory distress syndrome, shock, and trauma; (2) half of 29 m6A-RMRs were downregulated in atherosclerosis; (3) inflammatory bowel disease and rheumatoid arthritis modulated m6A-RMRs more than lupus and psoriasis; (4) some organ failures shared eight upregulated m6A-RMRs; end-stage renal failure (ESRF) downregulated 85% of m6A-RMRs; (5) Middle-East respiratory syndrome coronavirus infections modulated m6A-RMRs the most among viral infections; (6) proinflammatory oxPAPC modulated m6A-RMRs more than DAMP stimulation including LPS and oxLDL; (7) upregulated m6A-RMRs were more than downregulated m6A-RMRs in cancer types; five types of cancers upregulated ≥10 m6A-RMRs; (8) proinflammatory M1 macrophages upregulated seven m6A-RMRs; (9) 86% of m6A-RMRs were differentially expressed in the six clusters of CD4+Foxp3+ immunosuppressive Treg, and 8 out of 12 Treg signatures regulated m6A-RMRs; (10) immune checkpoint receptors TIM3, TIGIT, PD-L2, and CTLA4 modulated m6A-RMRs, and inhibition of CD40 upregulated m6A-RMRs; (11) cytokines and interferons modulated m6A-RMRs; (12) NF-κB and JAK/STAT pathways upregulated more than downregulated m6A-RMRs whereas TP53, PTEN, and APC did the opposite; (13) methionine-homocysteine-methyl cycle enzyme Mthfd1 downregulated more than upregulated m6A-RMRs; (14) m6A writer RBM15 and one m6A eraser FTO, H3K4 methyltransferase MLL1, and DNA methyltransferase, DNMT1, regulated m6A-RMRs; and (15) 40 out of 165 ROS regulators were modulated by m6A eraser FTO and two m6A writers METTL3 and WTAP. …”
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Toward accurate prediction of carbon dioxide (CO2) compressibility factor using tree-based intelligent schemes (XGBoost and LightGBM) and equations of state by Behnam Amiri-Ramsheh, Aydin Larestani, Saeid Atashrouz, Elnaz Nasirzadeh, Meriem Essakhraoui, Ali Abedi, Mehdi Ostadhassan, Ahmad Mohaddespour, Abdolhossein Hemmati-Sarapardeh

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