Application of deep learning model based on unenhanced chest CT for opportunistic screening of osteoporosis: a multicenter retrospective cohort study by Chengbin Huang, Dengying Wu, Bingzhang Wang, Chenxuan Hong, Jiasen Hu, Zijian Yan, Jianpeng Chen, Yaping Jin, Yingze Zhang

“…Abstract Introduction A large number of middle-aged and elderly patients have an insufficient understanding of osteoporosis and its harm. …”
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What are parents' preferences for Human Papillomavirus vaccination promotion messages and communication? Application of a discrete choice experiment to a French Caribbean setting by Frédérique G. E. Dorleans, Jonathan Sicsic, Valérie Henry, Isabelle Bonmarin, Gwladys Nadia Gbaguidi, Lucie Leon, Jocelyn Raude, Jacques Rosine, Judith E. Mueller

“…Methods We conducted a cross-sectional survey in public and private middle age schools in Guadeloupe in June 2023 using an online questionnaire. …”
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Association between red cell distribution width—albumin ratio and all-cause mortality in intensive care unit patients with heart failure by Ni Li, Junling Li, Kai Wang

“…Subsequent analysis revealed that the inclusion of RAR significantly improved the prognostic value on the basis of SOFA and APACHE Ⅱ, and the concordance index increased from 0.636 to 0.658 for SOFA, from 0.682 to 0.695 for APACHE Ⅱ (p < 0.001 for both).ConclusionThe study found that high level of RAR was independently associated with an increased risk of 1-year all-cause mortality in ICU patients with heart failure, with a stronger effect in young and middle-aged patients and a threshold effect, which could potentially serve as an early warning indicator for high-risk populations.…”
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The relationship between non-HDL-C/HDL-C ratio and bone mineral density: an NHANES study by Shuo Qi, Biao Peng, Zhanwang Xu, Daodi Qiu, Guoqing Tan

“…In the age subgroup, the negative correlation between NHHR and BMD is strongest in the younger group (18–30 years), gradually weakening in the middle-aged (31–44 years) and older groups (45–59 years). …”
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Heatstroke characteristics and meteorological conditions in Hefei, China: thresholds and driving factors by Xueliang Deng, Liang Zhao, Changchun Xiao, Rui Dai, Qianqian Xu, Yeqing Yao, Caimeng Liang, Lei Yao, Dongyan He

“…The highest frequency of heatstroke occurrence was found to be concentrated in the middle age group (40–59 years old). According to the statistical analysis, air temperature and relative humidity were the most important meteorological factors that influenced the occurrence of heatstroke. …”
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Gender-specific dual effects of physical activity on depression and mortality: a nine-year cohort study in Chinese adults aged 45 and above by Dan Shan, Dan Shan, Meina Yang, Meina Yang, Kunyan Zhou, Kunyan Zhou

“…Specific relationships between PA, depression, and mortality were then investigated by applying multivariate logistic regression and Cox proportional hazards models.ResultsHighest quantile levels of PA were correlated with a 37% increase in the risk of new-onset depression in middle-aged (45–59 years) and older adults (>60 years). …”
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Clinical and endoscopical and morphofunctional scores in evaluation of development of gastroesophageal reflux disease in various age groups by M. A. Osadchuk, A. M. Zolotovitskaya, N. V. Kireyeva, S. N. Nikolenko, I. M. Kvetnoy

“…The catarrhal form of GERD at middle-aged patients develops on a background of gastritis with signs of atrophy, associated to H. pylori infection, contaminations of distal esophagus by H. pylori and foci of gastric metaplasia, dysfunction of motility of upper regions of the gut on a background of hyperplasia of NO-synthase and endothelin-1-producing cells of the esophagus and the stomach. …”
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Fatigue in living kidney donors compared to a German general population sample: an exploratory study by Dilek Akkus, Adrian Westenberger, Gunilla Einecke, Gunilla Einecke, Wilfried Gwinner, Uwe Tegtbur, Mariel Nöhre, Martina de Zwaan

“…However, higher fatigue in donors was associated with more donation regret, a more negative relationship with the recipient, a more negatively perceived recipient health, less perceived family support, and more financial burden.ConclusionFatigue is less prevalent particularly in older donors and predictors of fatigue presented in the general population sample seem to have little importance in the donors. However, middle-aged female donors might be more prone to develop fatigue. …”
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Age-stratified analysis of the BMI-kidney stone relationship: findings from a national cross-sectional study by Liuliu Zhou, Wei Gu, Yufeng Jiang, Haimin Zhang

“…This non-linear relationship suggests that the impact of BMI on kidney stone risk varies by age and should be considered in clinical strategies.ConclusionHigh BMI is significantly associated with an increased risk of kidney stones, particularly among middle-aged and older adults. The relationship between BMI and kidney stones is non-linear, highlighting the need to develop age-specific BMI management strategies to reduce the occurrence of kidney stones.…”
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The association between frailty and falls among individuals aged 60 years and older residing in community settings and experiencing hip fractures in China: a cross-sectional study by Lan Jiang, Shulong Ding, Juxia Wang

“…Objectives Previous studies have established a correlation between frailty and an increased risk of falls among middle-aged and elderly individuals within community settings. …”
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Carbon sequestration effects of the typical restored vegetation types in Eastern Qinling Mountains by XU Xiaoming, YAN Shanshan, PENG Xiaobang

“…The carbon density of forest ecosystems was higher in the middle- aged forest stage and near-mature forest stage. …”
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Clinical analysis of 1,038 cases of odontogenic jawbone cysts by Chongli Du, Zeyu Wang, Duoduo Lan, Ruikun Zhu, Dong Wang, Hanying Wang, Chengao Wan, Tingyi Gao, Rui Han, Liang Liu, Kai Zhang

“…The age distribution of patients was between 4 and 89 years, and the high incidence age group was youth and middle age, accounting for 66.67% of the total number of cases. …”
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Efficacy of Olmesartan/Amlodipine Single‐Pill Combination on 24‐h Mean Systolic Blood Pressure Measured by Ambulatory Monitoring in Non‐Responders to Valsartan or Candesartan Monot... by Woo‐Baek Chung, Sang‐Hyun Ihm, Yun‐Seok Choi, Ho‐Joong Youn

“…Isolated systolic hypertension (ISH) is the most prevalent form of hypertension in middle‐aged and elderly individuals. Patients aged over 55 years who did not achieve the target systolic blood pressure (SBP < 140 mmHg) with valsartan 80 mg or candesartan 8 mg for at least 4 weeks were included. …”
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A Digital Behavior Change Intervention for Health Promotion for Adults in Midlife: Protocol for a Multidimensional Assessment Study by Dagmar Soleymani, Dominique Pougheon-Bertrand, Rémi Gagnayre

“… BackgroundTo support lifelong health promotion and disease prevention, Santé publique France studied the methodology for building a social marketing scheme with a digital intervention targeting middle-aged adults, specifically socioeconomically disadvantaged groups. …”
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Walking for transport and all-cause mortality: a prospective cohort study of Australian community-dwelling older adults by Rory Wolfe, Neville Owen, Ben Beck, Yang Chen, David W Dunstan, Alice Owen, Robyn L Woods, Danijela Gasevic, Joanne Ryan, Shivangi Shah, Carlene Britt

“…Background Walking for transport may prolong survival in younger and middle-aged adults; however, evidence for older adults is scarce. …”
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Time-series forest age estimation in Xinjiang based on forest disturbance and recovery detection by Lili Zhai, Mei Zan, Mao Ye, Jia Zhou, Cong Xue, Shunfa Yang, Yuntong Liu

“…From 1992 to 2022, Xinjiang experienced a net increase in forest area of 28580.69 km2; (3) the forest age distribution from 1991 to 2022 indicates a predominance of young and middle-aged forests, with the proportion of old forests remaining between 30 % and 40 %, showing a gradual annual increase. …”
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Characteristics, clinical manifestations and management of leprosy in KwaZulu-Natal, South Africa: A 20-year retrospective study by J S Sons, Z N Mkhize, N C Dlova, C Aldous, P R Bhat, A V Chateau

“…The majority of patients were male and middle aged, with a disproportionate representation of black South Africans. …”
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Efficacy of small-diameter core decompression with platelet-rich plasma in early osteonecrosis of the femoral head: a retrospective study by Haiwei Tang, Yahao Lai, Enze Zhao, Kai Zhou, Gang Chen, Zongke Zhou

“…Abstract Background Osteonecrosis of the femoral head (ONFH) is a challenging condition, primarily affecting young and middle-aged individuals, which results in hip dysfunction and, ultimately, femoral head collapse. …”
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Therapeutic alliance impact on analgesic outcomes in a real-world clinical setting: An observational study by Barrachina Jordi, Margarit César, Andreu Blanca, Zandonai Thomas, Ballester Pura, Muriel Javier, Cutillas Esperanza, Peiró Ana M.

“…Patients were predominantly middle-aged (75 % women, 72 % retired), experiencing moderate pain (VAS 40–70 mm) on average, and under a high morphine equianalgesic dosage (95 ± 88 mg per day, mainly tapentadol or fentanyl). …”
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Efficacy of MCU-based and 3D-FEA for Improving Cervical Spondylosis by Meigui KE, Ruixu XU, Ningying HUANG, Hai GUO, Xinghui YAN, Nanxi WU, Sidong DOU

“…After 12 weeks of treatment, VAS scores were lower in the experimental group and in all subgroups than in the control group(<italic>P</italic>&lt;0.05 and <italic>P</italic>&lt;0.017, respectively);and there was a statistical difference in the degree of pain relief in each age subgroup(<italic>P</italic>&lt;0.05), suggesting that young patients had better pain relief than middle-aged and elderly patients. Patients in both groups showed varying degrees of increase in cervical mobility and muscle strength in all directions(<italic>P</italic>&lt;0.05), 12 weeks of treatment with significant differences between the experimental and control groups and between subgroups(<italic>P</italic>&lt;0.05 and <italic>P</italic>&lt;0.017, respectively);the C₄-C₇disc stress and C₄-C₇crotal joint capsule stress were reduced to varying degrees between age subgroups compared to the pre-treatment period in this group. …”
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