Effects of PM2.5 exposure and air temperature on risk of cardiovascular disease: evidence from a prospective cohort study by Zhihang Zhang, Ran An, Haoyan Guo, Xuanru Yang

“…This study aimed to examine the long-term effects of PM2.5 exposure and air temperature on CVD based on a cohort study of middle-aged and older populations in China.MethodsA total of 9,316 non-CVD adults (≥40 years old) who joined the China Health and Retirement Longitudinal Study between 2011 and 2018 were included in our analysis. …”
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A comparative longitudinal study between bilateral and unilateral totally extraperitoneal repair among patients with unilateral inguinal hernia at a tertiary care hospital in easte... by Bikash Kumar Sah, Jatin Goel, Vijay Pratap Sah, Bhawani Khanal, Abhijeet Kumar, Rakesh Kumar Gupta

“…CONCLUSION: There is no significant difference in pain, complications, and recurrence between both groups, with one-fourth of patients having OCH. Young to middle-aged patients can easily tolerate the longer operative time at the cost of slightly more blood loss. …”
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A comprehensive analysis of percutaneous liver biopsy characteristics and pathological manifestations in a large patient cohort (2009–2024) by Minling Cao, Jiayi Zeng, Jiayu Wang, Junmin Jiang

“…Patients with hepatitis B complicated by MASLD exhibited disease exacerbation in middle age, with both liver inflammation and fibrosis grading worsening as age advanced. …”
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The effect of court surfaces on physiological responses and game activities of recreational senior tennis players by Bulent Kilit, Ersan Arslan, Yusuf Soylu

“…This study contributes to the understanding of how the court surface impacts middle-aged recreational players, indicating that training and preparation should be adapted to meet the unique demands of different court surfaces.…”
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Does Pre-existing Diabetes Correlate with Long COVID-19 in Europe? Evidence from the Analysis of the Survey of Health, Ageing and Retirement in Europe’s Corona Surveys by Sarah Cuschieri, Piotr Wilk

“…To investigate whether having pre-existing diabetes increases the risk of developing long COVID-19 in the population of middle-aged and older adults (≥50 years old) in Europe, while assessing if this relationship can be accounted for or is modified by the known long COVID-19 and diabetes risk factors (age, sex, hospitalization, pre-existing hypertension, and weight status). …”
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Predictors of New Onset Dysglycemia Post COVID-19 by Jonita Fernandes, Alphonsa Mary, Aanchal Sebastian, Franciosalgeo George, Jyothi Idiculla

“…Conclusion: A high incidence of dysglycemia over 6 months post-COVID-19 infection, especially in those with higher BMI, comorbidities, and in those in the middle age group warrants serial long-term monitoring of glucose levels in view of the high background risk of diabetes in the Asian population.…”
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BMI gain and dietary characteristics are risk factors of MASLD in non-obese individuals by Hirokazu Taniguchi, Miho Ueda, Yukiko Kobayashi, Takatomo Shima

“…A total of 4,100 non-obese middle-aged and older participants (1,636 men and 2,464 women) were followed up for an average of 6.44 ± 4.16 years. …”
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The effects and durability of an 8-week dynamic neuromuscular stabilization program on balance and coordination in adult males with intellectual disabilities: a randomized controll... by Hamed Babagoltabar-Samakoush, Behnoosh Aminikhah, Saeid Bahiraei

“…Conclusion This study provides robust evidence that DNS exercises can significantly enhance balance and neuromuscular coordination in middle-aged males with IDs, with improvements maintained over two months post-training. …”
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Genome-wide analysis in northern Chinese twins identifies twelve new susceptibility loci for pulmonary function by Tong Wang, Weijing Wang, Chunsheng Xu, Xiaocao Tian, Dongfeng Zhang

“…Therefore, we conducted an GWAS to explore relationships between genetic variants and pulmonary function among middle-aged Chinese dizygotic twins and further validated the top variants using data from the UK Biobank (UKB). …”
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Which Occupations Did People Engage in during Lockdown? A European Cross-Sectional Descriptive Survey by Generation by Cynthia Engels, Lauriane Segaux, Amandine Ibanez, Florence Canouï-Poitrine, Charlotte Lafont

“…We conducted an online, cross-sectional survey of young adults (YAs, aged 18-39), middle-aged adults (MAs, aged 40-59), and older adults (OAs, aged 60 or over). …”
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Diet quality, psychological factors and their associations with risk factors of cardiovascular disease: a cross-sectional pilot study by Anneli Peolsson, Sanna Nybacka, Mireille Ryden, Per Leanderson

“…This pilot study aims to investigate the relationship between adherence to a healthy diet, CVD risk factors, psychological factors and sociodemographic variables among middle-aged adults in Sweden.Methods Data were collected from March to December 2012 in the SCAPIS diet sub-study, where a total of 200 participants aged 50–64 years were enrolled. …”
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Web-Based Exercise and Nutrition Intervention to Improve Leg Muscle Strength and Physical Functioning in Older Adults: Pre-Post Pilot Study by Berber Gijsbertha Dorhout, Nick Wezenbeek, Lisette C P G M de Groot, Pol Grootswagers

“…The 1 repetition maximum knee extension strength and repeated chair rise test improved significantly during the 24-week intervention with a mean difference of 7.0 kg (95% CI 4.8-9.3; PPP ConclusionsThe results of the web-based exercise and nutrition intervention Uni2Move indicate potential improvements of muscle strength and physical functioning in healthy middle-aged and older adults. Providing such lifestyle interventions on the internet could reach an increased number of older adults, providing the opportunity to contribute to the health and independence of the rapidly growing aging population.…”
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Carbon Budget Assessment and Influencing Factors for Forest Enterprises in the Key State-Owned Forest Area of the Greater Khingan Range, Northeast China by Hui Wang, Wenshu Lin, Jinzhuo Wu, Zhaoping Luan

“…The interaction between paired factors enhances the explanatory power of their impact, and the effects of different influencing factors exhibit both positive and negative variations across forest enterprises. In addition, the middle-aged forest tending area and average annual precipitation positively influenced forest area and soil pH, indirectly enhancing the carbon budget through multifactor interactions. …”
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Case report: Atypical young case of MV1 Creutzfeldt-Jakob disease with unusually long survival by Lucie Yeongran Ahn, Mark L. Cohen, Mark L. Cohen, Ignazio Cali, Ignazio Cali, Tia Russell, Jessica Ludwig, Xun Jia, Alberto Bizzi, Lawrence B. Schonberger, Ryan A. Maddox, Rohini Paul, Tania C. Ghazarian, Jaspreet Garcha, Mostafa Hammoudi, Brian Stephen Appleby, Brian Stephen Appleby, Brian Stephen Appleby, Brian Stephen Appleby

“…Though the median age at onset and disease duration vary depending on the subtype of sporadic CJD (sCJD), the disease typically affects middle-aged to elderly individuals with a median survival of 4–6 months. sCJD in younger individuals is extremely rare. …”
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Trends in incidence, mortality, and DALYs of cystic echinococcosis in Central Asia from 1992 to 2021: an age-period-cohort analysis by Wulan Talafuhan, Kaibinuer Tuoheti, Ye Lixia, Qi Shuang, Mieyier Yeerjiang, Guzalinuer Aizezi, Wei Jingjing, Peierdun Mijiti, Peierdun Mijiti

“…The highest incidence rates were among middle-aged and older adult populations. Although mortality and DALY rates decreased across all age groups, the decline was less than the global trend. …”
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Serum choline, leptin and interleukin-6 levels in fibromyalgia syndrome-induced pain: a case–control study by Elif Baris, Izel Topaloglu, Elif Akalin, Emre Hamurtekin, Seray Kabaran, Ayse Gelal, Reyhan Ucku, Mualla Aylin Arici

“…Abstract Background Fibromyalgia Syndrome (FMS) predominantly affects middle-aged women, characterized by musculoskeletal pain, fatigue, and cognitive issues. …”
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The trend of DALY of breast, colorectal, oral, and cervical cancers in Taiwan in 2005–2017 by Chun-Hui Lin, Cheng-Chieh Hsieh, Si-Yu Chen, Hong-Ru Chen, Szu-Chieh Chen

“…The highest DALYs consistently occurred in the 50–69 age group across all cancer types, highlighting the significant burden on middle-aged populations.…”
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Relation of Follicular Fluid Soluble Receptor for Advanced Glycation End-Products Concentration and Anti Mullerian Hormone in Polycystic Ovary Syndrome and Non-PCOS Women Referring... by Neda Emami, Ashraf Moini, Samira Vesali

“…The results show that the levels of these receptors (sRAGE)show their specific effects in young women and women over 40 years old and not in middle age and target the ovarianreserve. It seems to act as a defensive shield in older women and increase fertility in young women.…”
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Two rare cases of primary clear cell adenocarcinoma of the urethra: clinical experience, case report and literature review by Bohao Jiang, Jiyuan Hu, Benqiao Wang, Xujia Liu, Ling Tong, Yitong Xu, Hao Zhang

“…Primary symptoms include hematuria and changes in voiding habits. Middle-aged and elderly females are more susceptible to primary clear-cell adenocarcinoma of the urethra. …”
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Clinical Profile and Outcome in Patients with Coronary Slow Flow Phenomenon by Xiaogang Zhu, Hua Shen, Fei Gao, Sijing Wu, Qian Ma, Shuo Jia, Ziwei Zhao, Shan Tong, Zhihao Zhang, Yujie Zhou

“…CSFP affects predominantly patients at middle age and above but can occur in any age group; CSFP should be more concerned, particularly in patients >50 years old with hypertension and dyslipidemia.…”
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