Health economics assessment of statin therapy initiation thresholds for atherosclerosis prevention in China: a cost-effectiveness analysis by Tianyu Feng, Xiaolin Zhang, Jiaying Xu, Shang Gao, Xihe Yu

“…The model utilized the China-PAR prediction tool for ASCVD risk and incorporated data from a nationally representative survey and published meta-analyses of middle-aged and elderly Chinese populations. Four strategies were evaluated: a 7.5% 10-year risk threshold, the current guideline strategy, and a 15% threshold. …”
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SOCIO-ECONOMIC CONSEQUENCES OF IMMIGRATION IN ITALY by E. J. Tsareva

“…The increasing number of migrants has created a certain imbalance in different spheres of life and society. The middle-aged population in Italy is ever growing, thus migrants play an important role in filling the workforce depletion as well as flooding the labor market. …”
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Evaluation of the Proximity of Root Apices of Maxillary Posterior Teeth to the Maxillary Sinus Floor using CBCT among Different Age Groups: A Retrospective Study by Nadia Rasool, S. Vidhyadhara Shetty, Sajad A. Buch, Prathap MS Nair, S Kalaichelvan, Nishi Jayasheelan

“…Methods: CBCT scans of 150 patients were obtained from the institute’s database based on strict inclusion and exclusion criteria; such that an equal number of samples were obtained in the following three age groups: Group 1 – Young group (20–44 years), Group 2 – Middle age (45–59 years), Group 3 – Elderly (60–70 years). …”
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Diagnosis and Management of Acquired Hemophilia A: Case Reports and a Literature Review by Ikhwan Rinaldi, Findy Prasetyawaty, Siti Fazlines, Kevin Winston, Yusuf Aji Samudera Nurrobi, Jessica Leoni, Ilham Hidayat Restu Tulus Maha, Satrio Wicaksono, Abdillah Yasir Wicaksono, Averina Octaxena Aslani, Rizkania Ikhsani

“…The first patient was a young female, while the second and third patients were middle-aged and elderly males, respectively. All patients presented with a chief complaint of bruises without hemarthrosis and a history of bleeding. …”
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Auditory steady state response can predict declining EF in healthy elderly individuals by Xiaopeng Mao, Xiaopeng Mao, Nelly Shenton, Sadasivan Puthusserypady, Martin Johannes Lauritzen, Krisztina Benedek

“…The ViTs trained and cross-validated on time-frequency-transformed Electroencephalograms (EEGs) achieved an average cross-subject accuracy of 51.8% in identifying cognitive decline.ConclusionGamma-band ASSR characteristics are linked to early cognitive decline in middle-aged individuals, offering potential as biomarkers. …”
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Evaluation of machine learning-based regression techniques for prediction of diabetes levels fluctuations by Badriah Alkalifah, Muhammad Tariq Shaheen, Johrah Alotibi, Tahani Alsubait, Hosam Alhakami

“…Middle-Aged and Elderly people today face a variety of health problems as a result of their modern lifestyle, which includes increased work stress, less physical activity, and altered food habits. …”
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Impact of Mediterranean Diet Adherence on the Incidence of New‐Onset Hypertension in Adults With Obesity in Korea: A Nationwide Cohort Study by Jung‐Hwan Kim, Ji‐Won Lee, Yaeji Lee, Chung‐Mo Nam, Yu‐Jin Kwon

“…ABSTRACT This study investigated the association between adherence to the Mediterranean diet (MD) and new‐onset hypertension (HTN) in a cohort of community‐dwelling, middle‐aged, older Korean individuals with obesity. …”
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Long-Term Intracranial Progression-Free Survival in Lung Cancer Brain Metastases Extended Beyond 50 Months with Gubenxiaoyi Formula (GBXY): A Groundbreaking Case Study by Zhengzheng Yang, Haiming Li, Lei Chen, Shujiao Li, Dong Chen, Taicheng Lu, Tongjing Ding, Ruiyang Han, Peiyu Cheng, Xiaomin Wang

“…Case presentation Here, we present a case of a middle-aged female with lung cancer BM, whose condition was assessed as progressive post-standard treatment including two local surgeries (both involving resection of cerebellar space-occupying lesions), stereotactic radiotherapy, chemotherapy and EGFR-TKIs. …”
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Informal caregiving and mental health: results from the Belgian health interview survey 2013 and 2018 by Filip Van Droogenbroeck, Bram Spruyt, Pierre Gérain, Laura Van den Borre, Pierre Smith, Robby De Pauw, Sarah Dury

“…Informal caregivers were predominantly female, middle-aged, and often had no paid job. High-intensity caregivers (over 20 h/week) experienced significantly higher psychological distress compared to non-caregivers, whereas lower-intensity caregivers did not. …”
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What a women desire: Application of conjoint analysis for analysing the choice of menstrual hygiene products and factors influencing their consummatory behaviour by Tiwari Abhay Kumar, Patel Vaishali, Saroj Chitra

“…Background/Aim: Middle-aged adolescent girls and women experience menstruation, a normal and physiologic occurrence. …”
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Satisfaction with Nighttime Outdoor Activity Environment Among Elderly Residents in Old Gated Communities by Fang Wen, Liang Peng, Bo Zhang, Yan Zhang, Yuyang Zhang

“…“Aging in place” is the most popular choice for older people in China, with more than 90% of urban older people living in the same residential areas they did in middle age. Nighttime outdoor activity (NOA) is popular among the elderly and has a positive impact on both their physical and mental health. …”
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A Multimodal Approach to Analgesia in Anorectal Surgery by T. N. Garmanova, D. R. Markaryan, E. A. Kazachenko, A. M. Lukianov, M. A. Kazachenko, M. A. Agapov

“…Mainly anorectal disorders affect middle-aged people reducing their life quality. At the same time many articles aimed at studying only postoperative anesthesia. 2 researchers independently searched for articles published in Medline, Scopus, Cochrane, Web of Science, E-library databases using keywords. …”
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Depression among Tibetan residents in the Southeastern region of Qinghai-Tibet plateau: a cross-sectional study by Yuji Chen, Ga Long, Qing Huang, Ping Zhang, Nie Xu

“…Logistic regression analysis showed that middle-aged (OR 2.86, 95% CI 1.69–4.82, P < 0.01) and elderly people (OR 2.27, 95% CI 1.30–3.98, P < 0.01), living in ultra-high altitude areas (OR 3.48, 95% CI 1.35–2.91, P < 0.01) and low BMI (OR   4.31, 95% CI 1.33–13.93) are high-risk factors for depression. …”
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Efficacy of Neoadjuvant Chemotherapy DOX and XELOX Regimens for Patients with Resectable Gastric or Gastroesophageal Junction Adenocarcinoma by Yuan Tian, Qun Zhao, Yong Li, Liqiao Fan, Zhidong Zhang, Xuefeng Zhao, Bibo Tan, Dong Wang, Peigang Yang

“…Neoadjuvant DOX is an effective and feasible regimen and might represent an option for young and middle-aged patients with locally advanced, resectable gastric or gastroesophageal junction adenocarcinoma.…”
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Global burden of chronic kidney disease due to dietary factors by Lingtao Yin, Mengni Kuai, Zhuo Liu, Binbin Zou, Ping Wu

“…Furthermore, the burden of CKD was notably higher among middle-aged and elderly individuals, especially men aged 65 and above.ConclusionThe global disease burden attributed to dietary risk factors for CKD is increasing. …”
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Cardiometabolic deaths in black and white men: Tracing the risks from early- to mid-adulthood by Rebecca Arden Harris, Sameed Ahmed M. Khatana, Judith A. Long

“…Black and White men during the transition from early adulthood to middle age. Methods: Using 2022 National Vital Statistics System data and standard period life table methods, we estimated the risk of CMD death in hypothetical cohorts of Black and White men from age 25 to 45 years. …”
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The effects of age and other individual factors on radiation induced ESR signals from fingernails by Samayeh Azariasl, Samayeh Azariasl, Samayeh Azariasl, Hiroshi Yasuda, Hiroshi Yasuda

“…Interestingly, the fingernals of middle-aged donors who regularly took vitamin supplements showed significantly higher ESR signal intensities than those of similar-age donors who did not take supplements. …”
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Diverse clinical manifestations and prognosis in a couple’s mercury poisoning caused by skin-lightening creams: two case reports and literature review by Huixia Ji, Ye Chen, Dandan Liu, Tongzhou Zhou, Yuhua Tang

“…Skin exposure to mercury-containing creams occurs most commonly in young and middle-aged women and, in a few cases, in men. This article presents the symptoms and prognosis of a couple who developed mercury poisoning after cosmetic use of similar duration and dosage. …”
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The Unforeseen Diagnosis: Hyperparathyroidism-Jaw Tumour Syndrome Case Report and Review of the Literature by Maxim Barnett, Farhan Ahmed, Radu Mihai, Asha Rattan, Malik Asif Humayun

“…Primary hyperparathyroidism, a frequent cause of hypercalcaemia, is often seen among middle-aged female patients, typically resulting from an underlying single-gland adenoma. …”
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Risk of adverse cardiovascular events based on common genetic variants in 8-year follow-up of the LIPIDOGEN2015 population using the polygenic risk score (PRS): study design and me... by Maciej Banach, Martyna Fronczek, Tadeusz Osadnik, Agnieszka Gach, Dominik Strapagiel, Marcin Słomka, Mateusz Lejawa, Anna Goc, Ewa Boniewska-Bernacka, Anna Pańczyszyn, Gregory Y.H. Lip, Dimitri P. Mikhailidis, Peter P. Toth, Peter E. Penson, Jacek Jóźwiak

“…Polygenic risk scores (PRS) can be effective in predicting adverse coronary events in younger and middle-aged patients. Our main aim is to assess the utility of a new PRS created for the Polish population in predicting mortality during an 8-year follow-up in the nationwide LIPIDOGEN2015 population. …”
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