Association between serum uric acid levels and left ventricular hypertrophy based on electrocardiographic findings: a sex-specific analysis across cardiometabolic diseases by Anwar Ahmed Salim, Shin Kawasoe, Takuro Kubozono, Satoko Ojima, Satoshi Yamaguchi, Koji Higuchi, Yoshiyuki Ikeda, Hironori Miyahara, Koichi Tokushige, Mitsuru Ohishi

“…Serum UA levels are associated with LVH in middle-aged women and men without cardiovascular disease risk, suggesting the potential role of UA as an LVH marker. …”
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Clinical Characteristics, Intraoperative Findings, and Surgical Outcomes of Canalicular Laceration Repair with Monocanalicular Stent in Asia by Chun-Hsien Lin, Chun-Yuan Wang, Ying-Cheng Shen, Li-Chen Wei

“…Affected patients tended to be middle-aged, and deep laceration accounted for 64.6% of patients. …”
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Short-term effects of empagliflozin on preventing contrast induced acute kidney injury in patients undergoing percutaneous coronary intervention, a randomised trial by Zeinab Sadat Hosseini, Mohammad Javad Jamili, Behzad Ensan, Ghazaleh Donyadideh, Bahram Shahri, Hamid Eshraghi, Susan Darroudi, Mohsen Moohebati

“…These benefits were observed across various age groups, particularly in middle-aged and elderly, and those with varying renal function levels.…”
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Causal linkage between adult height and kidney function: An integrated population-scale observational analysis and Mendelian randomization study. by Sehoon Park, Soojin Lee, Yaerim Kim, Yeonhee Lee, Min Woo Kang, Kwangsoo Kim, Yong Chul Kim, Seung Seok Han, Hajeong Lee, Jung Pyo Lee, Kwon Wook Joo, Chun Soo Lim, Yon Su Kim, Dong Ki Kim

“…In conclusion, the results of this study suggest that a taller adult height is causally linked to worse kidney function in middle-aged to elderly individuals, independent of the effect of body mass index.…”
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Acupuncture for Chronic Prostatitis or Chronic Pelvic Pain Syndrome: An Updated Systematic Review and Meta-Analysis by Juanhong Pan, Song Jin, Quan Xie, Ying Wang, Zhipeng Wu, Jianfeng Sun, Tai Pin Guo, Di Zhang

“…Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a complex male dysfunction, mostly seen in young and middle-aged men with a history of more than 3 months. …”
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Adiponectin Gene Polymorphisms and Possible Susceptibility to Metabolic Syndrome among the Sudanese Population: A Case-Control Study by Altaf S. Mosad, Ghada A. Elfadil, Alsadig Gassoum, Khanssa M. Elamin, Nazik Elmalaika Obaid Seid Ahmed Husain

“…Four hundred and twenty middle-aged adults participated in this community-based case-control research. …”
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The effect of a barley-based food product in alleviating knee osteoarthritis discomfort symptoms in Egyptian female patients by Suzanne Fouad, Rasha Monir, Fatma A. Ibrahim, Ahmed M.S. Hussein, Heba F. Shafei, Aliaa El Gendy

“…Patients and methods The present study enrolled 51 Egyptian middle age females patients with a mean age of 51±8.37 years, diagnosed with bilateral grade two to three knee osteoarthritis were recruited from the National Research Centre rheumatology and rehabilitation clinic. …”
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Educating patients about health helps slow the progression of chronic kidney disease in the eastern region of India by Supriya Dasgupta, Reeti Debnath

“…Results: In this study, several factors were linked to elevated creatinine levels among CKD patients, including being in the middle-age range, male gender, living predominantly in urban areas, and working in business or service occupations. …”
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The impact of chronic disease diagnoses on smoking behavior change and maintenance: Evidence from China by Xinxin Chi, Xihua Liu, Cong Li, Wen Jiao

“…Conclusions Efforts to enhance smoking cessation in middle-aged and elderly patients with chronic diseases are crucial to improving health outcomes. …”
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An analysis of the burden of migraine and tension-type headache across the global, China, the United States, India and Japan by Rongjiang Xu, Ruonan Zhang, Liang Dong, Xiaonuo Xu, Xiaoping Fan, Jiying Zhou

“…Migraines are becoming more common in young and middle-aged women, so headache treatment professionals should invest more in patient education to raise awareness and improve self-management to reduce disease burden and medical costs.…”
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A comparative longitudinal study between bilateral and unilateral totally extraperitoneal repair among patients with unilateral inguinal hernia at a tertiary care hospital in easte... by Bikash Kumar Sah, Jatin Goel, Vijay Pratap Sah, Bhawani Khanal, Abhijeet Kumar, Rakesh Kumar Gupta

“…CONCLUSION: There is no significant difference in pain, complications, and recurrence between both groups, with one-fourth of patients having OCH. Young to middle-aged patients can easily tolerate the longer operative time at the cost of slightly more blood loss. …”
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A comprehensive analysis of percutaneous liver biopsy characteristics and pathological manifestations in a large patient cohort (2009–2024) by Minling Cao, Jiayi Zeng, Jiayu Wang, Junmin Jiang

“…Patients with hepatitis B complicated by MASLD exhibited disease exacerbation in middle age, with both liver inflammation and fibrosis grading worsening as age advanced. …”
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Does Pre-existing Diabetes Correlate with Long COVID-19 in Europe? Evidence from the Analysis of the Survey of Health, Ageing and Retirement in Europe’s Corona Surveys by Sarah Cuschieri, Piotr Wilk

“…To investigate whether having pre-existing diabetes increases the risk of developing long COVID-19 in the population of middle-aged and older adults (≥50 years old) in Europe, while assessing if this relationship can be accounted for or is modified by the known long COVID-19 and diabetes risk factors (age, sex, hospitalization, pre-existing hypertension, and weight status). …”
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BMI gain and dietary characteristics are risk factors of MASLD in non-obese individuals by Hirokazu Taniguchi, Miho Ueda, Yukiko Kobayashi, Takatomo Shima

“…A total of 4,100 non-obese middle-aged and older participants (1,636 men and 2,464 women) were followed up for an average of 6.44 ± 4.16 years. …”
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The effects and durability of an 8-week dynamic neuromuscular stabilization program on balance and coordination in adult males with intellectual disabilities: a randomized controll... by Hamed Babagoltabar-Samakoush, Behnoosh Aminikhah, Saeid Bahiraei

“…Conclusion This study provides robust evidence that DNS exercises can significantly enhance balance and neuromuscular coordination in middle-aged males with IDs, with improvements maintained over two months post-training. …”
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Which Occupations Did People Engage in during Lockdown? A European Cross-Sectional Descriptive Survey by Generation by Cynthia Engels, Lauriane Segaux, Amandine Ibanez, Florence Canouï-Poitrine, Charlotte Lafont

“…We conducted an online, cross-sectional survey of young adults (YAs, aged 18-39), middle-aged adults (MAs, aged 40-59), and older adults (OAs, aged 60 or over). …”
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Web-Based Exercise and Nutrition Intervention to Improve Leg Muscle Strength and Physical Functioning in Older Adults: Pre-Post Pilot Study by Berber Gijsbertha Dorhout, Nick Wezenbeek, Lisette C P G M de Groot, Pol Grootswagers

“…The 1 repetition maximum knee extension strength and repeated chair rise test improved significantly during the 24-week intervention with a mean difference of 7.0 kg (95% CI 4.8-9.3; PPP ConclusionsThe results of the web-based exercise and nutrition intervention Uni2Move indicate potential improvements of muscle strength and physical functioning in healthy middle-aged and older adults. Providing such lifestyle interventions on the internet could reach an increased number of older adults, providing the opportunity to contribute to the health and independence of the rapidly growing aging population.…”
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Carbon Budget Assessment and Influencing Factors for Forest Enterprises in the Key State-Owned Forest Area of the Greater Khingan Range, Northeast China by Hui Wang, Wenshu Lin, Jinzhuo Wu, Zhaoping Luan

“…The interaction between paired factors enhances the explanatory power of their impact, and the effects of different influencing factors exhibit both positive and negative variations across forest enterprises. In addition, the middle-aged forest tending area and average annual precipitation positively influenced forest area and soil pH, indirectly enhancing the carbon budget through multifactor interactions. …”
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Trends in incidence, mortality, and DALYs of cystic echinococcosis in Central Asia from 1992 to 2021: an age-period-cohort analysis by Wulan Talafuhan, Kaibinuer Tuoheti, Ye Lixia, Qi Shuang, Mieyier Yeerjiang, Guzalinuer Aizezi, Wei Jingjing, Peierdun Mijiti, Peierdun Mijiti

“…The highest incidence rates were among middle-aged and older adult populations. Although mortality and DALY rates decreased across all age groups, the decline was less than the global trend. …”
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Serum choline, leptin and interleukin-6 levels in fibromyalgia syndrome-induced pain: a case–control study by Elif Baris, Izel Topaloglu, Elif Akalin, Emre Hamurtekin, Seray Kabaran, Ayse Gelal, Reyhan Ucku, Mualla Aylin Arici

“…Abstract Background Fibromyalgia Syndrome (FMS) predominantly affects middle-aged women, characterized by musculoskeletal pain, fatigue, and cognitive issues. …”
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