Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia (DIPNECH): A Case of Indolent Pulmonary Nodules Diagnosed with Robotic-Assisted Navigational Bronchoscopy by Adam Purdy, Firas Ido, Deborah Stahlnecker

“…This disease is mainly diagnosed in middle-aged, nonsmoking females, and it is now accepted as a precursor lesion to pulmonary carcinoid tumors. …”
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Five-Month Observation of Persistent Diabetic Macular Edema after Intravitreal Injection of Ozurdex Implant by Dominik Zalewski, Dorota Raczyńska, Krystyna Raczyńska

“…However, reinjections involve a high risk of developing poststeroid cataracts, which is not without significance in middle-aged patients.…”
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Diabetic Ketoacidosis in Klinefelter Syndrome Sans Malignancy with Unusually Elevated Levels of CEA: A Case Report by Wo X, Yu X, Miao L, Mao Y, Tang K

“…This study reports the case of Diabetic ketoacidosis (DKA) concurrently with a significant increase in CEA levels (reaching 40.8 ng/mL) in patients with KS.Methods: This middle-aged KS patient was immediately treated for DKA upon admission. …”
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Gender Conditioning and Socio-economical Condition: its Association with Some Risk Factors for Atherosclerosis by Ana Mary Fernández Milán, Daysi Antonia Navarro Despaigne, Jorge Bacallao Gallestey

“…<strong><br />Objective:</strong> to determine the association between gender conditioning and socio-economical condition and some atherosclerosis risk factors in middle aged women. <strong><br />Method:</strong> a cross observational study was carried out in two doctors’ offices with socio-economical characteristics supposedly different belonging to the Polyclinic 19 de Abril at the municipality of Plaza de la Revolution, from January 2012 to June 2013. …”
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Overlap of Functional Gastrointestinal Disorders: Common Mechanisms of Pathogenesis as a Key to Rational Therapy by S. N. Mekhdiyev, O. A. Mekhdieva, O. M. Berko

“…FGID occurs in more than 40 % of people globally, mainly affecting the working-age population in young and middle-aged subjects. At the same time, more than 30 % of patients have a combination of 2 or more functional gastrointestinal (GI) disorders i.e. overlap syndrome. …”
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The Obesity Paradox and Cardiorespiratory Fitness by Paul A. McAuley, Nancy S. Smith, Brian T. Emerson, Jonathan N. Myers

“…We evaluated independent and joint associations of cardiorespiratory fitness and adiposity with all-cause mortality in 811 middle-aged (age, 53.3±7.2 years) male never smokers without documented cardiopulmonary disease or diabetes from the Veterans Exercise Testing Study (VETS). …”
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Monomorphic Ventricular Tachycardia as a Presentation of Giant Cell Myocarditis by Michael H. Chiu, Cvetan Trpkov, Saman Rezazedeh, Derek S. Chew

“…Idiopathic giant cell myocarditis (GCM) has a fulminant course and typically presents in middle-aged adults with acute heart failure or ventricular arrhythmia. …”
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Effects of housing conditions on health and gut microbiome of female cynomolgus monkeys and improvement of welfare by checking menstruation under socially housed condition by Yunpeng Yang, Yong Lu, Changshan Gao, Yanhong Nie, Hongfei Wang, Yufei Huang, Haiyan Dong, Qiang Sun

“…Specifically, grouping the single-caged young monkeys to socially housed condition could decrease the relative abundance of Firmicutes and increase the relative abundance of Bacteroidetes, while separating the socially housed middle-aged monkeys into single cages showed the opposite trend. …”
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Neurobehavioral plasticity in the rodent gustatory system induced by regular consumption of a low-calorie sweetener during adolescence by Clare M. Mathes, Sarah J. Terrill, Juan P. Taborda-Bejarano, Sandrine Chometton, Mallory J. Witt, Gaurikka Mendiratta, Emily G. Gilman, Delenn R. Hartswick, Bo M. Anderson, Lindsey A. Schier

“…Results revealed that early-life LCS intake not only enhanced the avidity for a caloric sugar (fructose) when rats were in a state of caloric need, it increased acceptance of a bitterant (quinine) in Ace-K-exposed rats tested when middle-aged. These behavior shifts, which endured months after the end of Ace-K exposure, were accompanied by widespread changes in the peripheral taste system. …”
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Dietary Pattern and Metabolic Syndrome in Thai Adults by W. Aekplakorn, W. Satheannoppakao, P. Putwatana, S. Taneepanichskul, P. Kessomboon, V. Chongsuvivatwong, S. Chariyalertsak

“…To determine the dietary patterns of middle-aged Thais and their association with metabolic syndrome (MetS). …”
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Polymers for the treatment of Alzheimer’s disease by Yunfeng Zhu, Haibin Xu, Chaoyan Yu, Wenting Jiang, Xiaowen Hou, Mingyue Ma, Ji Wu

“…Alzheimer’s disease (AD) is one of the most common diseases of the central nervous system in the middle-aged and elderly population. It is a neurodegenerative disorder, and its main clinical symptoms include the loss of established memories, a decline in learning capacity, and the buildup of β-amyloid peptides. …”
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Outdoor activity time and depression risk among adults aged 40 years and older: a cross-sectional analysis of NHANES 2011–2018 data by Kai Liu, Cheng Guo, Juan Xie, Liming Cheng

“…Subgroup analysis revealed that this association was particularly pronounced among adults aged 40 and older, as well as non-Hispanic whites and non-Hispanic blacks.ConclusionEncouraging outdoor activities may represent an effective public health strategy to reduce depression risk, particularly among middle-aged and older adults and specific ethnic populations. …”
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Impact of diffuse idiopathic skeletal hyperostosis on quality of life and locomotive syndrome in community-dwelling older adults: the Yakumo study by Kazuma Ohshima, Hiroaki Nakashima, Naoki Segi, Sadayuki Ito, Jun Ouchida, Yasuhiko Takegami, Shinya Ishizuka, Ippei Yamauchi, Yukiharu Hasegawa, Kenta Murotani, Shiro Imagama

“…Thus, we aimed to evaluate the DISH effect on QOL and LS in community-dwelling middle-aged and older adults. Data of community volunteers who attended a health checkup in 2018–2019 were assessed. …”
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Effects of forest age and stand density on the growth, soil moisture content, and soil carbon content of Populus simoni plantations in the sandy area of western Liaoning, Northeast... by Hao Chen, Zhaowei Zhang, Xiangyu Yang, Xin Ai, Yutao Wang, Ping Liu

“…We found that DBH and TH increase with increasing stand density in young and middle-aged forests, but the opposite is true at near-maturity, maturity, and over-maturity, where DBH and TH decrease with increasing stand density. …”
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Low Serum Magnesium Level Is Associated with Microalbuminuria in Chinese Diabetic Patients by Baihui Xu, Jichao Sun, Xinru Deng, Xiaolin Huang, Wanwan Sun, Yu Xu, Min Xu, Jieli Lu, Yufang Bi

“…We concluded that low serum magnesium level was significantly associated with the prevalence of microalbuminuria in middle-aged and elderly Chinese.…”
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ENDOCRINE DISORDERS IN DOGS: EPIDEMIOLOGY, CLINICAL PRESENTATION, AND DIAGNOSTIC METHODS by Daniela Neagu, Vlad-Emil Luca, Răzvan Codea, Cristian Popovici, Anca Bărbos, Ștefania Dandea, Dragoș Hodor, Alexandra Biriș

“…Diabetes mellitus (55%) and hyperadrenocorticism (22%) were the most common, with seasonal trends noted for diabetes in spring and hyperadrenocorticism in winter. Middle-aged or geriatric dogs showed higher incidences, and overweight dogs frequently had Cushing's syndrome. …”
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Literature review of spontaneous subarachnoid haemorrhage: risk factors, diagnostic features, and complications (Part I) by J. Grigaitė, G. Rutkauskaitė, L. Piliponis, J. Ščerbak, D. Jatužis, J. Valaikienė

“… Ruptured cerebral aneurysm-induced subarachnoid haemorrhage (SAH) is a common cause of disability and death in middle-aged people. SAH is more common in females than males, among non-white ethnicity, and is most commonly diagnosed in Finland and Japan. …”
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An Immunocompetent HIV-Negative Elderly Patient with Low-Grade Fever, Generalized Lymphadenopathy, Splenomegaly, and Acute Phase Response: Do Not Forget Castleman Disease by Kalliopi Azariadis, Maria Ioannou, Kalliopi Zachou, George N. Dalekos

“…Multicentric Castleman disease (MCD) is a rare lymphoproliferative disorder that mainly affects middle-aged patients with human immunodeficiency virus (HIV) infection. …”
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Association of anti-phospholipid antibodies and hepatitis B virus infection in Najaf Governorate by Ameer Mohammed Kadhim, Hawraa Ameer Mubark, Dhefaf Hameed Al-Mudhafar, Zainab Hayder Abdulmajeed

“…Conclusion: HBV may lead to the production of APLA in some patients without any other risk factors, especially in middle-aged patients.…”
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Driving Fatigue Prediction Model considering Schedule and Circadian Rhythm by Qi Zhang, Chaozhong Wu, Hui Zhang

“…With the cooperation of one commercial transportation company, a Naturalistic Driving Study (NDS) was conducted, and NDS data from thirty-four middle-aged drivers were selected for analysis. With regard to the circadian rhythms, commercial drivers operated the vehicle and started driving at around 09:00, 14:00, and 21:00, respectively. …”
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