Investigation and analysis of the demand for smart home automation in patients with ischemic stroke and functional impairment (脑梗死伴功能障碍患者对智慧居家模块需求的调查分析)... by FEI Cailian (费才莲), XIE Juan (谢娟), ZHANG Jingyi (张静怡), WANG Yu (王瑜), GAO Liandi (高连娣)

“…Objective To establish a comprehensive, scientific, and reasonable smart home automation system for patients with ischemic stroke and functional impairment by conducting a questionnaire survey on the requirements of a smart home automation system. Methods The researchers developed a questionnaire titled "Requirements of a smart home automation system for patients with ischemic stroke and functional impairment" to assess the specific needs of patients who suffered from ischemic stroke and were unable to live independently. …”
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Analysis of compliance with wearing hospital gowns and its influencing factors among inpatients in a certain third-grade class-A hospital in Changsha (长沙市某三甲医院住院患者病服穿着依从性及影响因素分析)... by HUANG Siting (黄思婷), HAN Huiwu (韩辉武), LI Bingfa (李兵发), ZHANG Jinghui (张京慧)

“…Objective To investigate the compliance with wearing hospital gown and its influencing factors among inpatients in a certain third-grade class-A hospital in Changsha, and provide reference for improving the quality of basic nursing. Methods Totally 3741 inpatients in a certain third-grade class-A hospital were selected as the research objects. …”
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Protective Mechanism of Alisol A 24-Acetate on Brain Microvascular Endothelial Cells in Mice with Cerebral Ischemia-Reperfusion Injury by TRPM2/Akt/GSK3β Pathway by LI Huihong, DENG Yunfei, WEI Wei, ZHAN Zengtu, LIN Libin, XUE Xiehua

“…ObjectiveTo explore the mechanism of Alisol A 24-acetate (24A) on improving brain microvascular endothelial cells (BMECs) injury after cerebral ischemia reperfusion in mice.MethodsA total of 45 10-week-old male C57BL/6 mice were randomly divided into sham surgery group, model group and 24A group, with 15 cases in each group. …”
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Modified Bloom's Taxonomy: Perspective of a Doctor of Philosophy Scholar by Wafa Omer

“…Integrative frameworks known as practice-based systems place a strong emphasis on converting theoretical knowledge into practical abilities for use in both professional and real-world settings.3 This method guarantees that learning is not only profound and long-lasting, but also immediately applicable and significant. …”
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Ophthalmological monitoring in patients with hypertension and coronary heart disease by L.K. Moshetova, I.V. Vorobyeva, A. Dgebuadze, O.D. Ostroumova, A.V. Arablinskiy, E.P. Delver, A.A. Belogurov

“…</i> </p> <p> <i><b>Patients and Methods:</b> 30 patients (58 eyes) with hypertension and CHD with coronary artery stenosis (group A) and 30 healthy controls (60 eyes, group B) were examined. …”
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Performance evaluation of four cascade impactors for airborne ultrafine-particle (UFP) collection: the influence of particle type, concentration, mass, and chemical nature by E. Eckenberger, A. Mittereder, N. Gawlitta, N. Gawlitta, J. Schnelle-Kreis, J. Schnelle-Kreis, M. Sklorz, D. Brüggemann, R. Zimmermann, R. Zimmermann, A. C. Nölscher

“…However, their small mass presents challenges for sampling and chemical characterization methods. Therefore, we conducted a comprehensive characterization and comparison of four cascade impactors suitable for separating and collecting UFPs – namely, the 120R Micro-Orifice Uniform Deposit Impactor (120R MOUDI-II), ultraMOUDI, electrical low-pressure impactor (ELPI), and personal nanoparticle sampler (PENS) – under controlled laboratory conditions and in a field application.…”
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Effect of auricular acupoint sticking and pressing therapy on preventing postoperative nausea and vomiting in patients undergoing thoracolumbar surgery under general anesthesia (耳穴... by CHEN Ying (陈英), XIE Wei (谢薇), YANG Mei (杨梅), REN Liwen (任丽雯), ZHANG Yating (张雅婷), YANG Ji (杨吉), REN Xiuya (任秀亚)

“…Objective To observe the effect of auricular acupoint sticking and pressing therapy on preventing postoperative nausea and vomiting in patients undergoing thoracolumbar surgery under general anesthesia. Methods To retrospectively analysis the clinical data of 126 patients who underwent posterior thoracolumbar surgery under general anesthesia, including 37 patients who underwent auricular point sticking and pressing 24 hours before surgery (group A), 48 patients who underwent auricular point sticking and pressing after surgery(group B) and 41 patients without auricular acupoint sticking and pressing therapy after operation (group C). …”
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Meta-analysis: p16INK4α (Cyclin Dependent Kinase Inhibitor 2A) is one of the major causes of nasopharyngeal cancer by Lao Đức Thuận, Nguyễn Thị Ngọc Thảo, Thiều Hồng Huệ, Nguyễn Trung Hiếu, Phạm Thị Thúy Ngọc, Trần Bích Thư, Lê Huyền Ái Thúy

“…Therefore, this article aims to provide further scientific evidence on the enhanced methylation status in the promoter region of CpG islands of NPC patients based on the analysis of the p16INK4α gene using statistical synthesis methods. The research results demonstrated an uneven expression frequency of the p16INK4α gene between the two patient groups and the control group. …”
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Key experimental technologies and their development directions for the exploration and production of deep coalbed methane by Xia YAN, Fengyin XU, Xianyue XIONG, Feng WANG, Chunhu LI, Jiyuan ZHANG, Borui XU, Qianhui CHENG, Xiong HU, Xueguang ZHU, Wei LIANG, Pu YUAN, Yanqing FENG, Zhenji WEI

“…However, the exploration and production of deep CBM are still confronted with many technical challenges, and there is a lack of studies on key experimental technologies related to the geological characteristics and engineering assessment of deep CBM reservoirs, the occurrence characteristics and production mechanisms of gas and water, the formulation of production systems, and methods for enhanced CBM recovery. Advances in ResearchGiven the characteristics of deep coal seams and CBM, this study identifies four challenges in the exploration and exploitation of deep coal seams: the collection of large coal samples, the high-temperature, high-pressure, and high-stress in-situ conditions, high-precision characterization and desorption of sub-nano- to nano-scale micropores, and the accurate determination of gas content. …”
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In vitro functional validation of anti-CD19 chimeric antigen receptor T cells expressing lysine-specific demethylase 1 short hairpin RNA for the treatment of diffuse large B cell l... by Zhi Guo, Zhi Guo, Mingxin He, Ning Liu, Yiqing Yang, Rui Sun, Jianxun Wang, Qiang Wang

“…Epigenetic modifications can regulate T cell activation, maturation and depletion; they can be applied to reduce T cell depletion, improve infiltration, and promote memory phenotype formation to reduce relapse after CAR-T cell therapy.PurposeWe propose to develop and validate in vitro the function of novel CAR-T cells for the treatment of DLBCL, which simultaneously express an anti-CD19 CAR with lysine-specific demethylase 1 (LSD1) short hairpin (sh)RNA to prevent depletion and prolong the survival of CAR-T cells.MethodsWe designed an shRNA sequence targeting LSD1 mRNA, and created a vector with the following elements: the U6 promoter driving expression of the LSD1 shRNA sequence, the EF1a promoter driving a second-generation anti-CD19 CAR sequence encoding an anti-CD19 single-chain variable fragment (FMC63), the CD8 hinge and transmembrane structural domains, the CD28 co-stimulatory structural domain, and the CD3ζ-activating structural domain. …”
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A phase 2, double-blind, placebo-controlled trial of a valproate/lithium combination in ALS patients by M.-C. Boll, M. Alcaraz-Zubeldia, C. Rios, D. González-Esquivel, S. Montes

“…A combination of lithium carbonate and valproic acid (VPA-Li) was shown to inhibit motor neuron death and delay disease progression. Methods: Outpatients with a typical ALS presentation were enrolled in a randomized, placebo-controlled trial to assess the efficacy of orally administered VPA-Li. …”
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Associations of sedentary time, sleep duration and physical exercise with multimorbidity among older adults in Shanghai, China: a cross-sectional study based on national physical f... by Kai Li, Jingjing Wang, Yuqin Rao, Fanhui Zheng, Ying Chen, Bo Zhai, Jintao Hong, Dao Wang, Chen Wang, Bao Liu

“…This study aims to examine the associations between key determinants of lifestyle behavior and various multimorbidity patterns. Methods In a cross-sectional sample of older adults (aged 60–79) from the Fifth National Physical Fitness Surveillance in Shanghai, latent class analysis (LCA) was used to identify multimorbidity patterns among 9 chronic diseases. …”
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Application of Zhuang medicine ironing therapy and external application in early functional rehabilitation of patients after anterior cruciate ligament reconstruction (壮医药熨联合壮医敷贴治疗... by HUANG Biqiu (黄碧秋), MO Lilu (莫理璐), LAN Yanglu (蓝阳露), ZHAO Xiangyue (赵香越)

“…Objective To explore the effect of Zhuang medicine ironing therapy combined with Zhuang medicine external application in the early rehabilitation of patients after anterior cruciate ligament reconstruction. Methods Totally100 patients who underwent arthroscopic anterior cruciate ligament reconstruction were selected as the study subjects. …”
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Association of tea consumption with all-cause/cardiovascular disease mortality in the chronic kidney disease population: an assessment of participation in the national cohort by Jin Li, Xing-Ling Chen, Xiao-Lu Ou-Yang, Xiao-Jiao Zhang, Yue Li, Shu-Ning Sun, Ling-Jun Wang, Zhong-Qi Yang, Shi-Hao Ni, Lu Lu

“…Background While there are numerous benefits to tea consumption, its long-term impact on patients with chronic kidney disease (CKD) remains unclear.Method Our analysis included 17,575 individuals with CKD from an initial 45,019 participants in the National Health and Nutrition Examination Survey (NHANES) (1999–2018). …”
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Tratamiento quirúrgico de las fracturas bifocales ipsilaterales de tibia: un reto para el cirujano by A. Ortega-Yago, M. Barrés-Carsí, A. Balfagón-Ferrer

“…Currently there is no gold standard regarding the ideal surgical treatment.The objective of this study is to analyze the surgical treatment and the radiographic and functional results, as well as the associated complication rate of ipsilateral bifocal tibia fractures. Material and methods: Retrospective observational study in our hospital from 2010 to 2022 of 24 patients who underwent bifocal fracture of the ipsilateral tibia. …”
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The role of teachers and administrators in supporting the adaptation of students with special needs in mainstream high schools by Amir Mahmood, Xiao Huang, Nadia Rehman

“…., 2017). This sampling method helps provide a more accurate and comprehensive understanding of the population under study. …”
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Understanding limb necrotizing infections: A comprehensive approach by A. Garrido-Hidalgo, J. García-Coiradas, M. Echevarría-Marín, S. Llanos, J.A. Valle-Cruz, F. Marco

“…This study analyzes the characteristics, demographics, complications, and treatment of NSTI in a hospital in Madrid, Spain. Methods: A retrospective observational study was conducted, including all surgically treated NSTI patients at our center from January 2016 to December 2022, examining epidemiological and clinical data. …”
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Ovarian stimulation alternatives for in vitro production of embryos in water buffaloes by Alexis Bandeo, José Luis Konrad, Natalia Vallejos, Pablo Ponce, Marina J. Sansinena, Gustavo Crudeli, Pablo Maldonado-Vargas

“…The aspirated oocytes or COCs (cumulus-oocyte complexes) were classified into grades (1 to 4) based on the number of cumulus layers present, according to the International Embryo Transfer Society method (IETS Manual). In vitro fertilization (IVF) was performed after 24 hours of oocyte in vitro maturation using cryopreserved semen from buffalo bulls of proven fertility. …”
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Estimación de Erosión Hidrica de Suelos para plan de Manejo del Campo Forestal Aguas Frías, Patagonia Argentina by Ana Cecilia Dufilho, María Cristina Frugoni, Pablo Macchi, Alan Thot

“…The classification of actual erosion was obtained from the method of the Bureau of Land Management (USDI) by visual inspection of seven aspects of erosion in surface. …”
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Current situation of central nervous system tumour survivors in a spanish hospital by Ivonne Marcela Rincón-Mantilla, Blanca Herrero, Elena Herranz Valero, Fernando Robles-Bermejo, Alba Herrera-Olivares, Felisa Vázquez-Gómez, Álvaro Lassaletta

“…The aim of our study was to evaluate late morbidity, health-related quality of life (HRQoL), self-esteem, functional status, adaptive behaviour, physical activity and social outcomes such as education, employment, relationship status and possession of a driver’s license, in addition to the role of LT effects of radiotherapy (RTx) on these outcomes. Methods: The study included 111 CNS tumour survivors with a minimum of 10 years of follow-up. …”
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