High-risk human papillomavirus: prevalence, association with clinical and morphological characteristics of invasive cervical cancer by L. S. Mkrtchian, V. I. Kiseleva, B. V. Boyko, L. I. Krikunova, V. A. Petrov, V. R. Gusarova, S. A. Ivanov, A. D. Kaprin, I. A. Zamulaeva

“…Analysis of contemporary literature sources dedicated to the study of characteristics of high oncogenic risk human papillomavirus (HPV), associative links of the virus’s molecular-genetic parameters with the clinical and morphological characteristics of invasive cervical cancer (ICC).Materials and methods. A literature search was conducted in electronic databases including the National Center for Biotechnology Information Search database (PubMed/Medline), ResearchGate, Scopus, Web of Science, Cancer Tomorrow, Global cancer observatory, Cochrane Library, eLIBRARY, DisserCat. …”
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Analysis of factors causing delays in seeking medical attention and its relationship with short-term prognosis in patient with acute ischemic stroke (急性缺血性脑卒中患者延迟就医原因与短期预后相关性分析)... by PENG Hong (彭红), CHEN Xiangyang (陈向阳), ZHANG Xiuliang (张修亮)

“…Objective To investigate the factors causing delays in seeking medical attention and its relationship with short-term prognosis in patient with acute ischemic stroke, and provide reference for the interventions on seeking timely medical attention. Methods Totally 131 patients with acute ischemic stroke who attended the hospital between September 2021 and August 2022 were included. …”
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Alcohol use and HIV suppression after completion of financial incentives for alcohol abstinence and isoniazid adherence: a randomized controlled trialResearch in context by Winnie R. Muyindike, Robin Fatch, Sara Lodi, Nneka I. Emenyonu, Allen Kekibiina, Julian Adong, Brian Beesiga, Kara Marson, Harsha Thirumurthy, Michael G. McDonell, Moses R. Kamya, Gabriel Chamie, Judith A. Hahn

“…Whether the short-term incentives influence long-term alcohol use and HIV viral suppression post-intervention is unknown. Methods: We analyzed twelve-month HIV viral suppression and alcohol use in the Drinkers’ Intervention to Prevent Tuberculosis study, a randomized controlled trial among PWH with latent TB and unhealthy alcohol use in south-western Uganda. …”
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Association of accelerated phenotypic aging, genetic risk, and lifestyle with progression of type 2 diabetes: a prospective study using multi-state model by Lulu Pan, Yahang Liu, Chen Huang, Yifang Huang, Ruilang Lin, Kecheng Wei, Ye Yao, Guoyou Qin, Yongfu Yu

“…We aimed to assess these associations and examine whether these associations varied by genetic risk and lifestyle. Methods We conducted a prospective cohort study that included 376,083 adults free of T2D and diabetes-related events at baseline in UK Biobank. …”
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Las brechas laborales que afectan a las mujeres desde la perspectiva de las ciencias económicas: un análisis de la producción científica en la base de datos Scopus - Labor market g... by Emanuel José Maldonado, Denis González-Argote, Rolando Eslava-Zapata, Alfredo Javier Pérez-Gamboa

“…Methodology: A mixed-methods approach was applied, combining a bibliometric study with qualitative thematic analysis. …”
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Evaluation of oral health status in patients with type 2 diabetes by Tahmineh Khoshbakhti, Vajehallah Raeesi, Gholamreza Sharifzadeh, Leili Alizadeh

“…So, the purpose of this study was to compare the oral health indicators of type 2 diabetic patients with non-diabetic controls. Methods: In this case-control study, A total of 306 individuals included in the study (103 T2DM cases and 203 non-diabetic controls) in the age range of 40 to 60 years old. …”
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Fixed-dose combination treatment regimen to control intraocular pressure in glaucoma by V.N. Alekseev, I.R. Gazizova, A.M. Gadzhiev

“…</i> </p> <p> <i><b>Patients and Methods:</b> 54 patients (93 eyes) with POAG were enrolled in this 4-week study. …”
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Significance of changes in levels of neutrophil extracellular traps during development of silicosis in mice by Lu HAN, Ruru CHEN, Yulu XIONG, Ziye GUO, Hailan HE, Xiaohui HAO, Heliang LIU, Lingli GUO

“…ObjectiveTo observe the levels of NETs and pathological changes in the lungs of silicotic mice after different duration of SiO2 exposure, and to confirm the possible role and significance of NETsin the development of SiO2-induced pulmonary fibrosis. MethodsA total of 28 SPF male C57BL/6J mice were randomly divided into a control group, and a model group, and the model group was subdivided into, a 2 d model group, a 7 d model group, and a 28 d model group, with 7 mice in each group. …”
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Comprehensive analysis of Pan-Immune Inflammation and all-cause mortality in rheumatoid arthritis: a database-driven approach, 1999-2018 by Muradil· Mardan, Huoliang Zheng, Qingyin Xu, Shaokuan Song, Zeyu Lu, Hui Deng, Hao Cai, Qizhu Chen, Bingyi Yang, Kudelaiti· Abuduwufuer, Pengbo Chen, Bo Li, Shengdan Jiang, Leisheng Jiang, Xin-feng Zheng

“…However, its role in predicting outcomes in RA patients remains largely unexplored.ObjectivesThis study aimed to evaluate the association between PIV and all-cause mortality in RA patients, investigate nonlinear relationships, and identify threshold effects.MethodsData from the 1999–2018 National Health and Nutrition Examination Survey (NHANES) were used, including 1,882 RA patients. …”
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Enhanced fibrotic potential of COL1A1hiNR4A1low fibroblasts in ischemic heart revealed by transcriptional dynamics heterogeneity analysis at both bulk and single-cell levels by Cheng Luo, Cheng Luo, Cheng Luo, Baoping Tan, Luoxiang Chu, Liqiang Chen, Xinglong Zhong, Yangyang Jiang, Yuluan Yan, Fanrui Mo, Hong Wang, Fan Yang, Fan Yang

“…Our aim is to identify the heart fibroblast (FB) subsets that most significantly promote fibrosis and the related critical genes as biomarkers for ischemic heart disease.MethodsThe single nuclei RNA sequencing (snRNA-seq) and bulk RNA sequencing datasets used in this study were obtained from the Gene Expression Omnibus (GEO). …”
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Tax Exemptions and R;D Expenditures in Iran Saeed Dorokhshi Moghaddam by Saeed Dorokhshi Moghaddam, Bahram Sahabi, Hassan Heydari, Sajad Barkhordari

“…In particular, the usual use of linear models is not a very accurate and correct method because it does not guarantee that the values predicted by these estimates are in the range of 0 and 1. …”
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A key technology for synergistic backfilling of coal-based solid waste and high-salinity wastewater by Shuning DONG, Shujiang YU, Xingling DONG, Buqin ZHANG, Xiaoming GUO, Xiaodong WANG, Kai WANG, Shibin ZHU, Boqiang WU, Lei LIU

“…However, existing technologies for high-salinity wastewater treatment are generally confronted with issues such as great initial investment and high operation costs of the treatment engineering. Methods This study developed a technology for the synergistic treatment of coal-based solid waste and high-salinity wastewater (also referred to as solid-liquid synergistic waste backfilling). …”
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Exploration of rituximab treatment strategies for membranous nephropathy adapted to the Chinese healthcare environment by Xiaolong Wang, Xueying Cao, Jie Wu, Shuang Liang, Jian Yang, Hong Wang

“…Abstract Purpose This study aimed to explore the specific efficacy of rituximab (RTX) in the treatment of membranous nephropathy (MN) and compare and analyze the differences in effectiveness among various treatment regimens, with the objective of identifying the optimal treatment protocol suitable for the medical environment in China. Patients and methods This retrospective study focused on patients with MN who were treated with RTX and hospitalized at the First Medical Center of PLA General Hospital between January 1, 2019, and December 30, 2022. …”
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High risk of asthma among early teens is associated with quantitative differences in mite and cat allergen specific IgE and IgG4: a modified Th2 related antibody response revisited... by Thomas A. Platts-Mills, Behnam Keshavarz, Jeffrey M. Wilson, Sheryl L. Rifas-Shiman, Samuel M. Ailsworth, Joanne E. Sordillo, Lisa Workman, Martin Chapman, Jonas Lidholm, Emily Oken, Diane R. Gold

“…However, this phenomenon is still poorly understood. Methods: We studied serum antibodies among 616 individuals in the Viva unselected birth cohort recruited at their early teen visit (mean age 13.1 SD 0.8). …”
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Mesenchymal stem cells from perinatal tissues promote diabetic wound healing via PI3K/AKT activation by Jiawei Huang, Qingwen Deng, Lai Ling Tsang, Guozhu Chang, Jinghui Guo, Ye Chun Ruan, Chi Chiu Wang, Gang Li, Hon Fai Chan, Xiaohu Zhang, Xiaohua Jiang

“…This study evaluates and compares the therapeutic potential of MSCs derived from perinatal tissues—human umbilical cord MSCs (hUCMSCs), human chorionic villi MSCs (hCVMSCs), and human decidua basalis MSCs (hDCMSCs)—in a diabetic wound healing model. Methods We performed in vitro and in vivo studies to compare the efficacy of hUCMSCs, hCVMSCs, and hDCMSCs. …”
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Health literacy assessment and analysis of influencing factors in pregnant women with gestational diabetes mellitus in Southwest China by Fangmei Tang, Fangmei Tang, Li Gu, Li Gu, Xiujing Guo, Xiujing Guo, Wenjing Fu, Wenjing Fu, Benyi He, Yuqing Song, Yuqing Song, Dehua Li, Dehua Li

“…Given that the HLS-14 has not been used in GDM previously, its reliability and validity testing was included as a secondary objective.MethodIt was a cross-sectional survey with 565 GDM pregnancies. …”
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Epidemiology, Controversies, and Dilemmas of Perioperative Nutritional Risk/Malnutrition: A Narrative Literature Review by He M, Long Y, Peng R, He P, Luo Y, Zhang Y, Wang W, Yu X, Deng L, Zhu Z

“…Current controversies and dilemmas in this field include the low rates of nutrition screening and medical nutrition therapy, numerous nutrition screening tools and malnutrition diagnostic criteria, no consensus on optimal assessment method, low level of evidence-based clinical nutrition research and lack of in-depth mechanistic studies, inconsistent timing of nutrition assessment, lack of reports for community hospitals, small hospitals, and low/middle-income countries or regions, and under-recognition of micronutrient malnutrition. …”
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PREVALENCE OF WORK-RELATED MUSCULOSKELETAL DISORDERS AMONG IRANIAN ORTHOTISTS AND PROSTHETISTS: A STUDY ON WORK-RELATED QUALITY OF LIFE by Sarina Azizi, Vahideh Moradi, Behnam Hajiaghaei, Taher Babaee

“…A group of 263 orthotists and prosthetists were invited to complete the questionnaires using a simple random sampling method. The data from 188 respondents were analyzed. …”
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Research Reports on Assessment of Handwriting Ability in Children Aged 6-12 Years by Using Smart Handwriting Analysis Recognition Platform by HAN Ping, YANG Wenyi, XIE Yiyang, XIE Qiurong, WANG Jiawei, YANG Caihong, ZHAN Shiqi, YAN Zhaoshan, ZHANG Yu

“…ObjectiveBy computerized analysis of writing ability assessment data, to accurately assess the quality and proficiency of writing among primary school students, and to provide data support for accurate screening and assessment of those with writing difficulties.MethodsA cross-sectional study was conducted to evaluate the writing ability of 1 085 students from grade 1 to grade 6 in the Experimental Primary School Affiliated to Minjiang Teachers College, Fuzhou, Fujian Province, using the smart handwriting analysis recognition platform (SHARP). …”
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Transcriptomic profiles of monocyte-derived macrophages exposed to SARS-CoV-2 VOCs reveal immune-evasion escape driven by delta by Alessia Gallo, Josè Camilla Sammartino, Roberta Vazzana, Roberto Giambruno, Claudia Carcione, Nicola Cuscino, Salvatore Castelbuono, Vitale Miceli, Matteo Bulati, Daniele Lilleri, Irene Cassaniti, Pier Giulio Conaldi, Fausto Baldanti

“…The success of each VOC, as well as the virus fitness, were enabled by altered intrinsic functional properties and, reasonably, to virus antigenicity changes, conferring the ability to evade a primed immune response. Methods We analysed the gene expression profiles of monocyte-derived macrophages (MDM) isolated from whole blood of healthy participants exposed to the 5 different SARS-CoV-2 VOC: D614G, Alpha (B.1.1.7), Gamma (P1), Delta (B.1.617.2), and Omicron BA.1 (B.1.1.529), and to the HCoV-OC43 strain, a coronavirus already present in the population before the SARS-CoV-2 pandemic. …”
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