Radiotherapy-induced Hypothalamic-Pituitary axis dysfunction in adult Brain, head and neck and skull base tumor patients – A systematic review and Meta-Analysis by J.M.J. Paulissen, C.M.L. Zegers, R.M. Houben, D. Hofstede, M. Kars, H.M. van Santen, F.J.P. Hoebers, D.K.M. De Ruysscher, D.B.P. Eekers

“…The purpose of this systematic review and meta-analysis is to investigate literature on HP dysfunction after radiation for non-pituitary brain, HN, or SB tumors at adult age, aiming to give insight in the prevalence of HP dysfunction related to radiation dose. Materials and methods: Literature search of the PubMed database was performed for HP dysfunction after radiotherapy in adult patients. …”
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Electroacupuncture Relieves Suppression of Autophagy in Interstitial Cells of Cajal of Diabetic Gastroparesis Rats by Xing Wei, Yaping Lin, Dongfeng Zhao, Xiaojuan Xiao, Qiao Chen, Siyi Chen, Yan Peng

“…In this study, we aimed to figure out the relationship between DGP and autophagy of ICCs. Methods. Sixty Sprague-Dawley (SD) rats were randomly divided into normal control group (NC, 10) and modeling group (50). …”
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Design and application of path-based health education form for inpatients in rheumatology and immunology department (风湿免疫科住院患者健康教育路径表单的设计与应用)... by ZHONG Yingying (仲莹莹), XU Renju (徐任菊), ZHU Yuxuan (朱昱璇), ZHANG Qiong (张琼)

“…Objective To explore the design and application effect of path-based health education form for inpatients in the Department of Rheumatology and Immunology. Methods A health education group in the Department of Rheumatology and Immunology was established. …”
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NL-Augmenter: A Framework for Task-Sensitive Natural Language Augmentation by Kaustubh Dhole, Varun Gangal, Sebastian Gehrmann, Aadesh Gupta, Zhenhao Li, Saad Mahamood, Abinaya Mahadiran, Simon Mille, Ashish Shrivastava, Samson Tan, Tongshang Wu, Jascha Sohl-Dickstein, Jinho Choi, Eduard Hovy, Ondřej Dušek, Sebastian Ruder, Sajant Anand, Nagender Aneja, Rabin Banjade, Lisa Barthe, Hanna Behnke, Ian Berlot-Attwell, Connor Boyle, Caroline Brun, Marco Antonio Sobrevilla Cabezudo, Samuel Cahyawijaya, Emile Chapuis, Wanxiang Che, Mukund Choudhary, Christian Clauss, Pierre Colombo, Filip Cornell, Gautier Dagan, Mayukh Das, Tanay Dixit, Thomas Dopierre, Paul-Alexis Dray, Suchitra Dubey, Tatiana Ekeinhor, Marco Di Giovanni, Tanya Goyal, Rishabh Gupta, Louanes Hamla, Sang Han, Fabrice Harel-Canada, Antoine Honoré, Ishan Jindal, Przemysław Joniak, Denis Kleyko, Venelin Kovatchev, Kalpesh Krishna, Ashutosh Kumar, Stefan Langer, Seungjae Ryan Lee, Corey James Levinson, Hualou Liang, Kaizhao Liang, Zhexiong Liu, Andrey Lukyanenko, Vukosi Marivate, Gerard de Melo, Simon Meoni, Maxine Meyer, Afnan Mir, Nafise Sadat Moosavi, Niklas Meunnighoff, Timothy Sum Hon Mun, Kenton Murray, Marcin Namysl, Maria Obedkova, Priti Oli, Nivranshu Pasricha, Jan Pfister, Richard Plant, Vinay Prabhu, Vasile Pais, Libo Qin, Shahab Raji, Pawan Kumar Rajpoot, Vikas Raunak, Roy Rinberg, Nicholas Roberts, Juan Diego Rodriguez, Claude Roux, Vasconcellos Samus, Ananya Sai, Robin Schmidt, Thomas Scialom, Tshephisho Sefara, Saqib Shamsi, Xudong Shen, Yiwen Shi, Haoyue Shi, Anna Shvets, Nick Siegel, Damien Sileo, Jamie Simon, Chandan Singh, Roman Sitelew, Priyank Soni, Taylor Sorensen, William Soto, Aman Srivastava, Aditya Srivatsa, Tony Sun, Mukund Varma, A Tabassum, Fiona Tan, Ryan Teehan, Mo Tiwari, Marie Tolkiehn, Athena Wang, Zijian Wang, Zijie Wang, Gloria Wang, Fuxuan Wei, Bryan Wilie, Genta Indra Winata, Xinyu Wu, Witold Wydmanski, Tianbao Xie, Usama Yaseen, Michael Yee, Jing Zhang, Yue Zhang

“… Data augmentation is an important method for evaluating the robustness of and enhancing the diversity of training data for natural language processing (NLP) models. …”
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Tumor mutational burden and survival on immune checkpoint inhibition in >8000 patients across 24 cancer types by Vivek Subbiah, Samuel J Klempner, Neeraj Agarwal, David P Carbone, Amit Mahipal, Shilpa Gupta, David Fabrizio, Jeffrey S Ross, Gerald Li, David R Gandara, Miles C Andrews, Jonathan W Riess, Ramez N Eskander, Ryon P Graf, Geoffrey R Oxnard, Sarah Sammons, Jeremy Snider, Lilia Bouzit, Cheryl Cho-Phan, Megan Price, Julia C F Quintanilha, Richard Sheng Poe Huang

“…Using a large real-world dataset with validated survival endpoint data, we evaluated clinical validity of TMB measurement by the test in over 8000 patients across 24 cancer types who received single-agent immune checkpoint inhibitor (ICI).Methods Patients with advanced-stage cancers from 24 cancer types treated with single-agent anti-PD(L)1 therapy in standard-of-care settings were included. …”
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Effect of gender on the ocular surface after trabeculectomy by A.V. Antonova, V.P. Nikolaenko, V.V. Brzheskiy, A.Ya. Vuks

“…</p> <p> <b>Patients and Methods: </b>this study enrolled 443 patients (168 men and 275 women) who underwent surgical interventions for uncontrolled primary open-angle glaucoma (POAG) in 2016–2020 and were followed up for 6–24 months. …”
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Diagnostics and treatment of gastroesophageal reflux disease: clinical guidelines of the Russian gastroenterological association by V. T. Ivashkin, I. V. Mayev, I. . A.s. Trukhmanov, Ye. K. Baranskaya, O. B. Dronova, O. V. Zayratyants, R. G. Sayfutdinov, A. A. Sheptulin, T. L. Lapina, S. S. Pirogov, Yu. A. Kucheryavy, O. A. Storonova, D. N. Andreyev

“…To present the latest data on adequate diagnostic methods, treatment approaches and features of rational pharmacotherapy of gastroesophageal reflux disease (GERD) based on the principles of evidence­based medicine to general practitioners. …”
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Torrefaction of bamboo pellets using a fixed counterflow multibaffle reactor for renewable energy applications by W. Hidayat, B.A. Wijaya, B. Saputra, I.T. Rani, S. Kim, S. Lee, J. Yoo, B.B. Park, L. Suryanegara, M.A.R. Lubis

“…This study aims to investigate the properties and viability of torrefied G. pseudoarundinacea pellets for solid fuel applications to fill existing knowledge gaps about this technology’s potential.METHODS: A fixed counter-flow multi-baffle reactor was used to torrefy G. pseudoarundinacea bamboo pellets. …”
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Effect of Sunflower (Helianthus annus L.) Hulls with Different Particle Sizes on Growth Performance and Physiological Responses of Broiler Chickens Fed Different Levels of Protein by Najibeh Beigzadeh, Smayyeh Salari, Faegheh Zaefarian, Shima Hosseinifar

“…This study investigates the performance of broilers fed on low-density crude protein diets with increasing particle size of sunflower (Helianthus annus L.) hulls.Materials and Methods: This experiment aimed to examine the effect of sunflower hull particle size on the performance and physiological response of broiler chickens fed with different protein levels. …”
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Lesion Location and Possible Etiology of Acute Unilateral Vestibulopathy by Zhang M, Wang J, Xue S, Liu S, Li K, Zhao T, Feng Y, Sui R, Yang B, Yang X

“…The study aimed to explore the lesion site and possible etiology of AUVP.Methods: This study is a retrospective study. Twenty-three AUVP patients who attended the neurology outpatient clinics of our hospital from January 2020 to March 2022 were included. …”
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Comparison of cardiovascular risk prediction models developed using machine learning based on data from a Sri Lankan cohort with World Health Organization risk charts for predictin... by Anuradhani Kasturiratne, Hithanadura Janaka de Silva, Chamila Mettananda, Anuradha Supun Dassanayake, Norihiro Kato, Rajitha Wickremasinghe, Maheeka Solangaarachchige, Prasanna Haddela

“…Patients aged 40–74 years admitted to CNTH during the study period with incident CV events or a disease other than an acute CV event (CVE) with complete data for CVD risk calculation were used for external validation of the model.Methods Using the follow-up data of the cohort, we developed two ML models for predicting 10-year CV risk using six conventional CV risk variables (age, gender, smoking status, systolic blood pressure, history of diabetes, and total cholesterol level) and all available variables (n=75). …”
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Clinical and molecular outcomes from the 5-Year natural history study of SSADH Deficiency, a model metabolic neurodevelopmental disorder by Itay Tokatly Latzer, Jean-Baptiste Roullet, Wardiya Afshar-Saber, Henry H. C. Lee, Mariarita Bertoldi, Gabrielle E. McGinty, Melissa L. DiBacco, Erland Arning, Melissa Tsuboyama, Alexander Rotenberg, Thomas Opladen, Kathrin Jeltsch, Àngels García-Cazorla, Natalia Juliá-Palacios, K. Michael Gibson, Mustafa Sahin, Phillip L. Pearl

“…Abstract Background Succinic semialdehyde dehydrogenase deficiency (SSADHD) represents a model neurometabolic disease at the fulcrum of translational research within the Boston Children’s Hospital Intellectual and Developmental Disabilities Research Centers (IDDRC), including the NIH-sponsored natural history study of clinical, neurophysiological, neuroimaging, and molecular markers, patient-derived induced pluripotent stem cells (iPSC) characterization, and development of a murine model for tightly regulated, cell-specific gene therapy. Methods SSADHD subjects underwent clinical evaluations, neuropsychological assessments, biochemical quantification of γ-aminobutyrate (GABA) and related metabolites, electroencephalography (standard and high density), magnetoencephalography, transcranial magnetic stimulation, magnetic resonance imaging and spectroscopy, and genetic tests. …”
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Lightweight Daylily Grading and Detection Model Based on Improved YOLOv10 by JIN Xuemeng, LIANG Xiyin, DENG Pengfei

“…The model aims to enhance detection accuracy by optimizing the network structure and loss functions while reducing parameters and computational costs, making it more suitable for deployment in resource-constrained agricultural production environments.[Methods]The dried daylilies selected from the Qingyang region of Gansu province as the research subject. …”
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Clinicopathological and molecular characterization of astrocytoma by Xiaoyan Wu, Wenfeng Peng, Xu Zhang, Tao Tang, Ling Deng, Yuxia Xu, Xiaoyun Liu, Fang Wang, Wujian Peng, Jianrong Huang, Xiaoni Zhong

“…Identifying mutant genes can aid in reliable and early diagnosis, as well as provide insights for the development of targeted therapies.MethodsThis study aims to investigate the clinicopathologic and molecular characteristics of astroblastoma. …”
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Newborn Screening Program for Cystic Fibrosis in Türkiye: Experiences from False-Negative Tests and Requirement for Optimization by Fevziye Çoksüer, Gökçen Kartal Öztürk, Handan Duman Şenol, Meral Barlık, Mehmet Mustafa Özaslan, Bahar Girgin Dindar, Ece Ocak, Ece Halis, Şükrü Atacan Öğütcü, Figen Gülen, Esen Demir

“…Study Design: A retrospective cohort study. Methods: Screening for CF was conducted in accordance with the national CF-NBS program within 48-72 hours of birth by collecting a few drops of heel blood on Guthrie paper. …”
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Impact of Ketogenic and Mediterranean Diets on Gut Microbiota Profile and Clinical Outcomes in Drug-Naïve Patients with Diabesity: A 12-Month Pilot Study by Vanessa Palmas, Andrea Deledda, Vitor Heidrich, Giuseppina Sanna, Giulia Cambarau, Michele Fosci, Lorenzo Puglia, Enrico Antonio Cappai, Alessio Lai, Andrea Loviselli, Aldo Manzin, Fernanda Velluzzi

“…This study extends previously published results evaluating the short-term (three months) impact of these NIs on the same patients. <b>Methods</b>: At baseline, patients were randomly assigned to either a VLCKD (KETO group) or a Mediterranean diet (MEDI group). …”
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Effect of ERAS-based sputum drainage nursing model on improving postoperative pulmonary function recovery in elderly patients with aneurysmal subarachnoid hemorrhage (基于ERAS模式的排痰护理... by CAO Shuonan (曹硕楠), YUAN Qiaoling (袁巧玲), LIU Ranran (刘冉冉)

“…Objective　Methods 120 elderly patients suffering from aneurysmal subarachnoid hemorrhage and receiving craniotomy from June 2019 to June 2021 were enrolled. …”
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Blinking characteristics analyzed by a deep learning model and the relationship with tear film stability in children with long-term use of orthokeratology by Yue Wu, Siyuan Wu, Yinghai Yu, Yinghai Yu, Xiaojun Hu, Ting Zhao, Yan Jiang, Bilian Ke

“…PurposeUsing deep learning model to observe the blinking characteristics and evaluate the changes and their correlation with tear film characteristics in children with long-term use of orthokeratology (ortho-K).Methods31 children (58 eyes) who had used ortho-K for more than 1 year and 31 age and gender-matched controls were selected for follow-up in our ophthalmology clinic from 2021/09 to 2023/10 in this retrospective case-control study. …”
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Investigating novel Streptomyces bacteriophage endolysins as potential antimicrobial agents by Jindanuch Maneekul, Amanda Chiaha, Rachel Hughes, Faith Labry, Joshua Saito, Matthew Almendares, Brenda N. Banda, Leslie Lopez, Nyeomi McGaskey, Melizza Miranda, Jenil Rana, Brandon R. Zadeh, Lee E. Hughes

“…From 250 putative endolysins, bioinformatic methods were used to select three putative endolysins for cloning and study: LL35lys, Nb26lys, and Tb42lys. …”
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Post-acute sequelae of hospitalised COVID-19 re-infection compared with hospitalised first-time infection: a population-based retrospective cohort study in Hong Kong by Yin Zhang, Francisco T T Lai, Shirley Chiu Wai Chan, Chak Sing Lau, Xue Li, Eric Yuk Fai Wan, Lung Yi Mak, Celine S L Chui, Ivan F N Hung, Esther Wai Yin Chan, Vincent Ka Chun Yan, Deliang Yang, Carlos Wong, Ian Chi-Kei Wong

“…Although preliminary studies have suggested that COVID-19 re-infection may have a cumulative effect on long-term outcome, differential effects of COVID-19 re-infection severe enough to be hospitalised on post-acute sequelae compared with hospitalised first-time infection have not been explored.Methods Retrospective cohort study using territory-wide electronic medical records databases in Hong Kong. …”
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