Analysis on the demand and influencing factors of virtual simulation training for Traditional Chinese Medicine nursing technology (中医护理技术虚拟仿真培训需求现状及影响因素分析)... by CHEN Yumei (陈玉梅), ZHANG Gai (张改), LI Shufang (李淑芳), KANG Yuwen (康玉闻), LI Qingwei (黎庆卫)

“…Objective To explore the current status of nursing staff's demand for virtual simulation training of Traditional Chinese Medicine (TCM) nursing technology, and analyze its influencing factors, in order to lay a theoretical foundation for the targeted development and application of TCM nursing simulation training system. Methods From July to October 2019, 320 nursing staff from three tertiary first-class TCM hospitals in Guangdong Province were selected. …”
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Utilization of patient-reported outcomes to assess adherence to relugolix when combined with stereotactic body radiation therapy for intermediate to high-risk prostate cancer by Kelly Gaudian, Min Jung Koh, Min Ji Koh, Ryan R. Collins, Shaine Eden, Zoya Zwart, Malika Danner, Alan Zwart, Mark Fallick, Deepak Kumar, Paul Leger, Nancy A. Dawson, Simeng Suy, Sean P. Collins

“…This study focuses on the use of the Simplified Medication Adherence Questionnaire (SMAQ) as a tool to assess relugolix adherence.MethodsRelugolix was initiated at least 2 months prior to questionnaire administration. …”
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Risk Factors of Portal Vein Thrombosis in Patients with Different Child-Pugh Classes Liver Cirrhosis by M. Yu. Nadinskaia, Kh. B. Kodzoeva, K. A. Gulyaeva, M.-D. E. Khen, D. I. Koroleva, M. A. Privalov, A. Kh. Tekaeva, V. R. Fedorov, S. G. Prokofev

“…Aim: to evaluate the frequency of portal vein thrombosis (PVT) and build predictive models of the development of PVT for patients with liver cirrhosis (LC) of A and B/C classes by Child-Pugh.Materials and methods. Research design is a case-control. The Case group included 130 patients with newly diagnosed PVT not caused by invasive hepatocellular carcinoma (HCC); 29 patients were assigned to class A, 101 patients were assigned to class B/C. …”
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Diversity in the medical research ecosystem: a descriptive scientometric analysis of over 49 000 studies and 150 000 authors published in high-impact medical journals between 2007... by Leo Anthony Celi, Jonathan Shaffer, Marie-Laure Charpignon, Liam G McCoy, Luis Filipe Nakayama, Jack Gallifant, Urvish Jain, Joao Matos, Pia Gabrielle I Alfonso, Marisa Cobanaj, Amelia Morel Fiske, Alexander J Gates, Frances Dominique V Ho, Mohammad Kashkooli, Naira Link

“…To evaluate disparities in gender and geographical representation among authors who have published in any of five top general medical journals, we conducted scientometric analyses using a large-scale dataset extracted from the New England Journal of Medicine, Journal of the American Medical Association, The BMJ, The Lancet and Nature Medicine.Methods Author metadata from all articles published in the selected journals between 2007 and 2022 were collected using the DimensionsAI platform. …”
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Prevalence and determinants of post-neonatal mortality in East Africa: a multilevel analysis of the recent demographic and health survey by Alebachew Ferede Zegeye, Desale Bihonegn Asmamaw, Wubshet D. Negash, Wubshet D. Negash, Tadele Biresaw Belachew, Elsa Awoke Fentie, Atitegeb Abera Kidie, Tsegaw Amare Baykeda, Samrawit Mihret Fetene, Banchlay Addis, Sisay Maru Wubante, Abel Endawkie, Tadesse Tarik Tamir

“…Thus, the aim of this study was to identify the prevalence of post-neonatal mortality in East African countries and the factors that are associated with it.MethodsSecondary data analysis was conducted using data from the most recent Demographic and Health Surveys, which included 11 East African countries between 2014 and 2022. …”
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A human visual cognitive mechanism based network for surface defect detection(基于人类视觉认知机制的表面缺陷检测) by 崔丽莎(CUI Lisha), 代润鹏(DAI Runpeng), 姜晓恒(JIANG Xiaoheng), 李飞蝶(LI Feidie), 陈恩庆(CHEN Enqing), 徐明亮(XU Mingliang)

“…HVCM-Net achieves superior detection performance on defect datasets GB-DET, NEU-DET, and DAGM2007 compared to other algorithms, demonstrating the effectiveness of the proposed method.(进行表面缺陷检测是确保产品性能、质量、美观度以及生产效率的重要手段。尽管人工智能在视觉检测领域取得了飞速发展，但基于生物视觉认知指导机器视觉学习的方法，仍是研究难点。…”
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Temporal trends in characteristics and outcome of heart failure patients with and without significant coronary artery disease by Entela Bollano, Björn Redfors, Araz Rawshani, Dimitrios Venetsanos, Sebastian Völz, Oskar Angerås, Charlotta Ljungman, Joakim Alfredsson, Tomas Jernberg, Truls Råmunddal, Petur Petursson, J. Gustav Smith, Oscar Braun, Henrik Hagström, Ole Fröbert, David Erlinge, Elmir Omerovic

“…Our objective was to assess temporal trends in CAG utilization, patient characteristics, and prognosis in HF patients undergoing CAG at a national level. Methods and results We used data from the Swedish Coronary Angiography and Angioplasty Registry. …”
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Efficacy and safety of Jianpi Qinghua granules for non-erosive reflux disease with spleen deficiency and damp-heat syndrome: a multicenter, randomized, double-blind, placebo-contro... by Tai Zhang, Tai Zhang, Tai Zhang, Tai Zhang, Guang Bai, Wei Wang, Lin Liu, Zhenghua Zhou, Haijie Ji, Beihua Zhang, Beihua Zhang, Beihua Zhang, Xudong Tang, Xudong Tang

“…Jianpi Qinghua (JQ) granules, a traditional Chinese medicine, have shown promise in treating NERD by targeting symptoms of spleen deficiency and damp-heat syndrome.PurposeThis study aims to evaluate the efficacy and safety of JQ granules in treating patients with NERD characterized by spleen deficiency and damp-heat syndrome.Study designA multicenter, randomized, double-blind, placebo-controlled clinical trial was conducted with a total of 78 NERD patients randomly assigned to receive either JQ granules or placebo for 4 weeks, followed by a 4-week follow-up period.MethodsSeventy-eight NERD patients with spleen deficiency and damp-heat syndrome were recruited and randomly assigned to receive either JQ granules (n = 39) or placebo (n = 39). …”
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Effect of Traditional Chinese Medicine Baduanjin exercise combined with remote ischemic conditioning on mild cognitive impairment after stroke (中医传统功法八段锦联合远隔缺血适应治疗脑卒中后轻度认知障碍的效果研究)... by XUE CHAO (薛超), LI Juan (李娟), FANG Qian (方茜), CHEN Lihua (陈丽华), HAO Mingqing (郝明青), CHEN Zuoxiu (陈作秀)

“…Objective To investigate the intervention effect of Traditional Chinese Medicine(TCM) Baduanjin exercise combined with remote ischemic conditioning therapy for patients with mild cognitive impairment in stroke. Methods Seventy patients with mild cognitive impairment after stroke were recruited as study subjects and randomly divided into control group(n=35) and intervention group(n=35). …”
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Iodine activates NLRP3 inflammasomes in PBMCs of patients with autoimmune thyroiditis and regulates Th1 and Th17 cell differentiation by Ying Wu, Qingling Guo, Yongping Liu, Xun Gong, Wei Sun, Yushu Li, Chenling Fan, Weiping Teng, Zhongyan Shan

“…Furthermore, we examined the effect of iodine on inflammasomes containing NLR family pyrin domain-containing 3 (NLRP3) and inflammasome activation of helper T (Th) cell differentiation regulation in cultured PBMCs. Methods: We collected PBMCs and serum samples from 50 patients with AIT with normal thyroid function and 50 controls matched for age and sex. …”
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Local and distant response to intratumoral immunotherapy assessed by immunoPET in mice by Aurélien Marabelle, Louis Meyblum, Lambros Tselikas, Thierry de Baere, Sandrine Susini, Fréderic Deschamps, Baptiste Bonnet, Céline Chevaleyre, Benoit Jego, Dimitri Kereselidze, Vincent Lebon, Charles Truillet

“…However, a comprehensive understanding of the local and systemic distribution of ICBs following intratumoral administration, as well as their impact on distant tumors, remains crucial for optimizing their therapeutic potential.To comprehensively investigate the distribution patterns following the intratumoral and intravenous administration of radiolabeled anti-cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) and to assess its corresponding efficacy in both injected and non-injected tumors, we conducted an immunoPET imaging study.Methods CT26 and MC38 syngeneic colorectal tumor cells were implanted subcutaneously on both flanks of Balb/c and C57Bl/6 mice, respectively. …”
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EZH2/miR-142-3p/HMGB1 axis mediates chondrocyte pyroptosis by regulating endoplasmic reticulum stress in knee osteoarthritis by Yang Chen, Shanshan Dong, Xin Zeng, Qing Xu, Mingwei Liang, Guangneng Liao, Lan Li, Bin Shen, Yanrong Lu, Haibo Si, Peifang Wei

“…This study aims to investigate the effect of ER stress on chondrocyte pyroptosis and the upstream regulatory mechanisms, which have rarely been reported. Methods:. The expression of the histone methyltransferase enhancer of zeste homolog 2 (EZH2), microRNA-142-3p (miR-142-3p), and high mobility group box 1 (HMGB1) and the levels of ER stress, pyroptosis, and metabolic markers in normal and OA chondrocytes were investigated by western blotting, quantitative polymerase chain reaction, immunohistochemistry, fluorescence in situ hybridization, fluorescein amidite-tyrosine-valine-alanine-aspartic acid-fluoromethyl ketone (FAM-YVAD-FMK)/Hoechst 33342/propidium iodide (PI) staining, lactate dehydrogenase (LDH) release assays, and cell viability assessments. …”
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Effect of extended care APPs based on the transtheoretical model of behavior change on self-management abilities in young and middle-aged patients with newly diagnosed diabetes mel... by YANG Yongfang (杨永芳), YAN Wei (严娓)

“…Objective To investigate the effect of extended care APPs based on the transtheoretical model of behavior change on indexes of glucose metabolism and self-management abilities in young and middle-aged patients with newly diagnosed diabetes mellitus. Methods Totally 76 young and middle-aged patients with newly diagnosed diabetes mellitus were divided into the control group (n=38, hospital admission between June and September, 2023) and the study group (n=38, hospital admission between October and December, 2023). …”
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The first experience with brolucizumab for neovascular age-related macular degeneration by A.N. Kulikov, D.S. Maltsev, A.Yu. Malafeeva, S.M. Perminova, V.R. Zhalimova, A.S. Vasiliev, A.A. Kazak

“…</i> </p> <p> <i><b>Patients and Methods:</b> this study enrolled 47 patients with nAMD divided into two groups. …”
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FGF21 and APOA1 mRNA-based therapies for the treatment of experimental acute pancreatitis by Amaya Lopez-Pascual, Eva Santamaria, Nuria Ardaiz, Iker Uriarte, Tiffany Palmer, Anne-Renee Graham, Celia Gomar, Roberto C. Barbero, M. Ujue Latasa, Maria Arechederra, Jesus M. Urman, Carmen Berasain, Antonio Fontanellas, Carlos L. del Rio, Maite G. Fernandez-Barrena, Paolo G.V. Martini, Joshua R. Schultz, Pedro Berraondo, Matias A. Avila

“…This study explores mRNA-based therapies delivering fibroblast growth factor 21 (FGF21) and apolipoprotein A1 (APOA1), alone and in combination, for treating experimental AP. Methods Liver-targeted lipid nanoparticles (LNP)-mRNA formulations encoding FGF21, APOA1, and a chimeric APOA1-FGF21, were first tested for protein expression and bioavailability in vitro and in mice fed a high-fat diet. …”
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Application of five-tone music therapy combined Wu Qin Xi exercise in nursing of patients with cervical spondylosis (五音疗法联合五禽戏锻炼在颈椎病护理中的应用)... by WANG Jitao (王稷陶), SUN Yanrong (孙艳荣), WANG Jiating (王佳婷), LIU Ying (刘营), ZHENG Mengqi (郑梦绮)

“…Objective To investigate the effect of Traditional Chinese Medicine (TCM) five-tone music therapy and Wu Qin Xi exercise in nursing of patients with cervical spondylosis. Methods Totally 82 patients with cervical spondylosis were randomly divided into the observation group and control group, with 41 cases in each group. …”
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New design paradigm for federated edge learning towards 6G:task-oriented resource management strategies by Zhiqin WANG, Jiamo JIANG, Peixi LIU, Xiaowen CAO, Yang LI, Kaifeng HAN, Ying DU, Guangxu ZHU

“…The rich data at the edge enables it to serve artificial intelligence model training, and design wireless resource management strategies with the goal of optimizing learning performance (such as optimizing model training time, learning convergence, etc.). Methods: Using the federated learning network architecture, this paper analyzes the resource allocation and user scheduling schemes: 1. …”
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Definitional differences in “outpatient” surgery can influence study outcomes related to total shoulder arthroplasty by Junho Song, MD, Jennifer Yu, BS, Avanish Yendluri, BS, William A. Ranson, MD, Nikan K. Namiri, MD, John J. Corvi, MD, David E. Kantrowitz, MD, Thomas Boucher, MD, Leesa M. Galatz, MD, Paul J. Cagle, MD, Bradford O. Parsons, MD, Robert L. Parisien, MD

“…The objectives of this study were (1) to characterize the differences in definition of “outpatient” surgery (hospital-defined outpatient [HDO] vs. same-day discharge [SDD]), and (2) to study the effect of different definitions on 30-day outcomes following TSA. Methods: The American College of Surgeons National Surgical Quality Improvement Program database was queried for patients who underwent TSA between 2011 and 2021. …”
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Prognostic value of intraductal carcinoma subtypes and postoperative radiotherapy for localized prostate cancer by Fang Cao, Qing Li, Tianyu Xiong, Yingjie Zheng, Tian Zhang, Mulan Jin, Liming Song, Nianzeng Xing, Yinong Niu

“…The purpose of the study is to identify the impact of IDC-P and its subtypes on the prognosis of patients undergoing post-operative radiotherapy (PORT) after radical prostatectomy (RP) due to localized prostate cancer(PCa). Methods We performed a retrospective study of patients with localized PCa treated by RP followed by PORT or not. …”
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Association between penicillin allergy labels and serious adverse events in hospitalized patients: a systematic review and meta-analysis by Shipeng Zhang, Shipeng Zhang, Tianyi Dong, Jiawen Xian, Jiawen Xian, Xinyue Xiao, Xinyue Xiao, Jiaqing Yuan, Jiaqing Yuan, Tong Zeng, Tong Zeng, Kuan Deng, Kuan Deng, Rui Fu, Hanyu Wang, Hanyu Wang, Yanjie Jiang, Xueying Li, Xueying Li

“…Therefore, to systematically evaluate these effects and investigate the association between adverse clinical outcomes and the Penicillin label, we conducted this meta-analysis.MethodSearches were conducted in the PubMed, Embase, Cochrane Library, and Web of Science databases from inception to 13 July 2024. …”
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