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119881
Association between METTL14 gene polymorphisms and risk of ovarian endometriosis
Published 2025-01-01“…The possibility that single nucleotide polymorphisms (SNPs) in the METTL14 gene contribute to susceptibility of endometriosis has not been thoroughly investigated.MethodsWe assessed the genotype frequencies of five potential functional METTL14 SNPs (rs298982 G>A, rs62328061A>G, rs9884978G>A, rs4834698C>T, and rs1064034A>T) in a Chinese population consisting of 458 patients with ovarian endometriosis and 462 healthy controls. …”
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119882
KDM6A facilitates Xist upregulation at the onset of X inactivation
Published 2025-01-01“…KDM6A mutations have been implicated in congenital disorders such as Kabuki Syndrome, as well as in sex differences in development and cancer. Methods Kdm6a was knocked out (KO) using CRISPR/Cas9 gene editing in hybrid female mouse embryonic stem (ES) cells derived either from a 129 × Mus castaneus (cast) cross or a BL6 x cast cross. …”
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119883
High prevalence of resistance to macrolides and fluoroquinolones in Mycoplasma genitalium isolated from patients in two Russian megalopolises – Moscow and St. Petersburg in 2021– 2...
Published 2024-09-01“…Petersburg in 2021–2024. Materials and Methods. A total of 530 M. genitalium DNA-positive specimens (urethral and cervical swabs) obtained from men and women from the STD clinic in St. …”
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119884
Comparison of Perioperative Outcomes of Holmium Laser Enucleation of the Prostate for Standard (≤149 ml) Versus Very Large (≥150 ml) Prostate Glands: Retrospective Analysis of a Pr...
Published 2025-01-01“…Background and objective: Our objective was to evaluate whether a very large prostate volume significantly affects the incidence of perioperative complications and compromises outcomes among patients undergoing holmium laser enucleation of the prostate (HoLEP). Methods: We retrospectively analyzed data for 1815 adult patients who underwent HoLEP at Evangelisches Krankenhaus Königin Elisabeth Herzberge, Berlin, between January 2019 and May 2024. …”
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119885
Impact of antiviral prophylaxis on EBV viremia and posttransplant lymphoproliferative disorders in solid organ transplant recipients: a systematic review and meta-analysis
Published 2025-01-01“…This study aimed to conduct a systematic review and meta-analysis to investigate this issue. Method A comprehensive search was conducted up to December 31, 2023, in databases including PubMed, Embase, and the Cochrane Library for retrospective and prospective studies comparing antiviral prophylaxis effects on EVB viremia and PTLD incidence in SOT recipients. …”
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119886
Effects of taurine on growth performance, body composition and physiological responses of western white shrimp, Litopenaeus vannamei broodstock
Published 2024-06-01“…Tau has been also implicated in osmoregulation, modulation of neurotransmitters, hormone release, and antioxidation. Materials and Methods: A 30-day feeding study was conducted to determine the effects of supplementing the Tau in the diet of broodstock western white shrimp. …”
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119887
Impact of remnant cholesterol on short-term and long-term prognosis in patients with prediabetes or diabetes undergoing coronary artery bypass grafting: a large-scale cohort study
Published 2025-01-01“…However, the role of remnant-C in this population has not yet been investigated. Methods Adult patients with prediabetes or diabetes undergoing isolated CABG were consecutively enrolled in a longitudinal cohort between 2013 and 2018. …”
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119888
The impact of preliminary patient hydration on physiological [18F]PSMA-1007 uptake in the urinary bladder on PET/CT
Published 2024-06-01“…The purpose of this study was to assess the impact of preliminary hydration of patients on [18F]PSMA‑1007 uptake in the urinary bladder.Materials and methods. Prospective, multicenter, randomized controlled study included 180 patients with PCa who underwent [18F]PSMA‑1007 PET/CT. …”
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119889
Construct validation of a complete postpartum health and well-being patient reported outcome measure: prospective cohort studyAJOG Global Reports at a Glance
Published 2025-02-01“…They were combined to achieve coverage of all important aspects of postpartum well-being outlined by the International Consortium of Health Outcomes (ICHOM). Methods: Recruitment took place in a tertiary university maternity hospital between April 3rd 2023, and October 28th 2023, with final responses collected in January 2024. …”
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119890
Relationship between changes in the triglyceride glucose-body mass index and frail development trajectory and incidence in middle-aged and elderly individuals: a national cohort st...
Published 2024-08-01“…This relationship is investigated in this study. Methods Data from 9135 participants in the China Health and Retirement Longitudinal Study (2011–2020) were analysed. …”
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119891
Clinical Characteristics of Fulminant Type 1 Diabetes Compared with Typical Type 1 Diabetes: One-Year Follow-Up Study from the Guangdong T1DM Translational Medicine Study
Published 2020-01-01“…This study was aimed at exploring the clinical features through one-year follow-up. Methods and Materials. Patients with T1DM finishing at least one-year follow-up from June 2011 to July 2018 were enrolled from Guangdong Type 1 Diabetes Translational Medicine Study. …”
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119892
Investigating the Effect of Different Levels of Butyric Acid Glycerides and Clove Oil on Growth Performance, Blood Parameters and Tibia Bone Characteristics of Broiler Chickens
Published 2024-09-01“…Therefore, the present study was designed to investigate the effect of different levels of butyric acid glycerides and clove oil on growth performance, blood parameters and tibia bone characteristics of broiler chickens. Material and Methods: A total of 300 male and female broilers (Ross 308) with a completely randomized design with a 2 × 3 factorial arrangement, two levels of butyric acid glycerides (0 and 0.2 %) and three levels of clove oil (0, 500 and 1000 mg/kg) were used. …”
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119893
The Impact of the COVID-19 Pandemic on Health and Health Care Experience in Those With Polycystic Ovary Syndrome
Published 2025-02-01“…The aim of this study was to assess the impact of the pandemic on the health and health care experience of those affected by PCOS.Patients and Methods: An online survey was conducted January 2021 to July 2022 in Canada, open to anyone who identified as having PCOS. …”
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119894
High SUVs Have More Robust Repeatability in Patients with Metastatic Prostate Cancer: Results from a Prospective Test-Retest Cohort Imaged with 18F-DCFPyL
Published 2022-01-01“…As such, we aimed to evaluate the test-retest repeatability of lesion uptake in a large cohort of patients imaged with 18F-DCFPyL. Methods. In this prospective, IRB-approved trial (NCT03793543), 21 patients with history of histologically proven PC underwent two 18F-DCFPyL PET/CTs within 7 days (mean 3.7, range 1 to 7 days). …”
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119895
The HFA‐PEFF score identifies ‘early‐HFpEF’ phenogroups associated with distinct biomarker profiles
Published 2022-06-01“…The aims of this pilot study are to (i) identify distinct phenogroups by cluster analysis of HFA‐PEFF domain scores in subjects that present with HF‐like symptoms and (ii) study whether these phenogroups may be associated with distinct blood proteome profiles. Methods and results Subjects referred to the Cardiology Centers of the Netherlands, location Utrecht, with non‐acute possibly cardiac‐related symptoms (such as dyspnoea or fatigue) were prospectively enrolled in the HELPFul cohort (N = 507) and were included in the current analysis. …”
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119896
[Translated article] Preoperative instillation of epinephrine and lidocaine can reduce surgical time in the endoscopic treatment of GTPS
Published 2025-01-01“…Hypothesis: An instillation of vasoconstrictors and local anaesthetics before endoscopy will cause less intraoperative bleeding, which will translate into shorter surgical time. Materials and methods: A prospective cohort was retrospectively divided based on the use or absence of a preoperative instillation of physiological saline solution with epinephrine and lidocaine. …”
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119897
Design and validation of a questionnaire on habits, health and exercise in the use of baby carriers
Published 2025-01-01“…The aim of our study was to design and validate the first self-administered questionnaire to assess babywearing habits and their impact on health and physical activity as a means to monitor musculoskeletal complaints in caregivers. Material and methods: 350 individuals who currently used or had used baby carrying systems in the last 10 years completed the questionnaire, which was previously subject to a pilot study in a panel of experts. …”
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119898
The effects of self-management intervention based on Information-Motivation-Behavioral model in patients receiving targeted therapy for lung cancer (基于IMB模型的自我管理干预在肺癌靶向治疗患者中的应用)...
Published 2024-11-01“…Objective To investigate the effect of self-management intervention based on Information-Motivation-Behavioral (IMB) model in the patients with advanced lung cancer receiving targeted therapy. Methods A total of 102 patients with advanced lung cancer receiving targeted therapy in a tertiary grade A hospital were divided into study group (n=51) and control group (n=51) according to the sequence of hospital admission. …”
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119899
Urine kidney injury molecule-1 predicts subclinical kidney disease among persons living with HIV initiating tenofovir disoproxil fumarate-based ART in Zambia
Published 2025-01-01“…This study aimed to determine whether the change from baseline in urine KIM-1 (δKIM-1) and NGAL (δNGAL) following 2 weeks of TDF use could predict subclinical TDF-associated nephrotoxicity before the overt manifestation as acute kidney disease after 3 months.MethodsA prospective cohort study of 205 PLWH was conducted at the Adult Center for Infectious Disease Research (AIDC) in Lusaka, Zambia. …”
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119900
A meta-analysis of randomized controlled trials: evaluating the efficacy of isokinetic muscle strengthening training in improving knee osteoarthritis outcomes
Published 2025-01-01“…We aimed to utilize a meta-analysis to evaluate the efficacy of isokinetic muscle strengthening training (IMST) as a rehabilitation treatment for KOA in lowland areas. Methods The study conducted a comprehensive search of the CNKI, WanFang Data, VIP Database, PubMed, Ovid MEDLINE (1946–), Cochrane Library, Embase, and CBM databases. …”
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