Knowledge, attitude, and perception of Pakistani populations toward monkeypox: a cross-section study by Humayun Yousaf, Abdul Qadeer, Muhammad Sohail, Maqbool Khan, Muhammad Farooq, Zakir Khan, Dalia Fouad, Yu-Chia Liu, Chien-Chin Chen, Chien-Chin Chen, Chien-Chin Chen, Chien-Chin Chen

“…We conducted this study to evaluate the general population’s knowledge, attitude, and perceptions of Mpox in Pakistan.MethodsFrom August 15 to August 30, 2022, 3465 participants in this cross-sectional study provided information via an online survey. …”
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Deciphering hub genes and immune landscapes related to neutrophil extracellular traps in rheumatoid arthritis: insights from integrated bioinformatics analyses and experiments by Yang Li, Yang Li, Jian Liu, Jian Liu, Yue Sun, Yue Sun, Yuedi Hu, Yuedi Hu, Qiao Zhou, Qiao Zhou, Chengzhi Cong, Chengzhi Cong, Yiming Chen, Yiming Chen

“…However, the underlying molecular mechanisms and key genes involved in NET formation in RA remain largely unknown.MethodsWe obtained single-cell RNA sequencing data of synovial tissues from the Gene Expression Omnibus (GEO) database and performed cellular annotation and intercellular communication analyses. …”
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Application of a new type of mesh density basket in cleaning and disinfection of small dental equipment (新型密纹篮筐在牙科小器械清洗消毒中的应用) by DENG Yanli (邓艳莉), TU Chengyun (徒成云), LI Yanyan (李严严)

“…Objective To investigate the application value of a new type of mesh density basket in cleaning and disinfection of small dental equipment. Methods Totally 120 root canal files were randomly divided into the observation group and control group, with 120 files in each group. …”
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Immunomodulatory Effects of Combination Therapy with Bushen Formula plus Entecavir for Chronic Hepatitis B Patients by Long-Shan Ji, Qiu-Tian Gao, Ruo-Wen Guo, Xin Zhang, Zhen-Hua Zhou, Zhuo Yu, Xiao-Jun Zhu, Ya-Ting Gao, Xue-Hua Sun, Yue-Qiu Gao, Man Li

“…To compare the clinical efficacy of the combination therapy with Bushen formula (BSF) plus entecavir (ETV) in naïve chronic hepatitis B (CHB) patients and that in CHB patients with partial virological response to ETV and explore the relevant immunoregulatory mechanism. Materials and Methods. Two hundred and twenty CHB patients were enrolled in the historical prospective cohort study. …”
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Etelcalcetide: What we know eight years since its approval by Pedro Freitas, Luciano Pereira

“…This narrative review aims to summarize the published data about etelcalcetide, focusing on biochemical, cardiovascular (CV) and bone endpoints, as well as adverse effects and all-cause mortality. Materials and methods: A literature review of the use of etelcalcetide in hemodialysis patients with SHPT was conducted. …”
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Immunomodulatory and growth-promoting effects of Rauwolfia serpentina root powder in broiler chicks challenged with Salmonella Gallinarum by Yingyu Zhang, Hiba Rehman, Farina Khattak, Maryam Tariq, Bushra Nisar Khan, Sadia Chaman, Ayaesha Riaz, Muhammad Ovais Omer, Aqib Ali, Qamar un Nisa, Muhammad Muddassir Ali, Gulbeena Saleem

“…Benth. ex Kurz) powder (RSP) on three key immune-related genes; Suppressor of cytokine signaling 3 (SOCS3), the quiescence-related gene P20K (P20K), and the major histocompatibility complex Class IIβ (MHC class IIβ), gut morphology and growth performance of broiler chicks infected with Salmonella Gallinarum.MethodsTwo hundred and forty day-old Hubbard classic chickens were randomly assigned to four groups: non-challenged control (NC), and Salmonella Gallinarum challenge group (SGC), and two treatment groups fed a basic diet supplemented with 1.5% Rauwolfia serpentina powder (RSP) with SGC (RSP-1) and 3% RSP with SGC (RSP-2), respectively, from day 3 till 28 days of age. …”
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Pharmacokinetic Analysis of an Isoniazid Suspension Among Spanish Children Under 6 Years of Age by Antoni Noguera-Julian, Emma Wilhelmi, Maria Cussó, Rob Aarnoutse, Angela Colbers, Loreto Martorell, Maria Goretti López-Ramos, Joan Vinent, Rosa Farré, Dolors Soy, Sílvia Simó-Nebot, Clàudia Fortuny

“…Currently, there are no INH suspensions available in Europe. <b>Methods</b>: We aimed to characterize the pharmacokinetics of a licensed INH suspension (10 mg/mL, Pharmascience Inc., Montreal, QC, Canada) in children receiving INH daily at 10 mg/kg in a single-center, open-label, non-randomized, phase IIa clinical trial (EudraCT Number: 2016-002000-31) in Barcelona (Spain). …”
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Intensified conditioning containing decitabine versus standard myeloablative conditioning for adult patients with KMT2A-rearranged leukemia: a multicenter retrospective study by Zhongli Hu, Zinan Feng, Shiqi Liu, Hai He, Ying Dong, Zhiping Fan, Yiqing Li, Fen Huang, Na Xu, Can Liu, Yunxin Zeng, Ping Zhu, Ren Lin, Hua Jin, Xiong Zhang, Ruijuan Sun, Qifa Liu, Li Xuan

“…We aimed to determine whether intensified conditioning containing decitabine (Dec) could reduce relapse compared with standard myeloablative conditioning in adult patients with KMT2A-r leukemia. Methods We performed a multicenter retrospective study at seven institutions in China. …”
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HDAC and MEK inhibition synergistically suppresses HOXC6 and enhances PD-1 blockade efficacy in BRAFV600E-mutant microsatellite stable colorectal cancer by Xin Li, Peng Yang, Jin Gu, Nan Chen, Dengbo Ji, Jinhong Xia, Jinying Jia, Zhuang Sun, Mengyuan Shi, Hanyang Wang, Zhaoya Gao

“…This study aims to identify a novel therapeutic strategy for this challenging subgroup.Methods We first performed a large-scale drug screening using patient-derived organoid models and cell lines to pinpoint potential therapies. …”
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Hospital and physician-based mental healthcare during 12 months of opioid agonist treatment for opioid use disorder: Exploring costs and factors associated with acute care. by Tea Rosic, Glenda Babe, Myanca Rodrigues, Brittany B Dennis, Richard Perez, Claire de Oliveira, Andrew Worster, Lehana Thabane, Zainab Samaan

“…We also explored individual-level characteristics associated with mental health care service use and estimated the costs of this care.<h4>Methods</h4>We linked observational cohort data collected from 3,430 individuals receiving treatment for OUD in Ontario, Canada, with health administrative records available for all individuals enrolled in Ontario's public health insurance program. …”
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Correlation between discharge readiness and uncertainty in illness among parents with preterm infants hospitalized in NICU (NICU早产儿父母出院准备度与疾病不确定感的相关性分析)... by TAN Jilei (谭继磊), WEI Qin (韦琴), LIANG Jie (梁洁), LIANG Hua (梁华), TENG Xiaoyun (滕小芸), TANG Lihua (唐利华), SONG Jingwen (宋静雯), HE Ting (何婷)

“…Objective To investigate the correlation between discharge readiness and uncertainty in illness among parents with preterm infants hospitalized in NICU, so as to provide a reference for clinical training. Methods Totally 75 parents with preterm infants were investigated using Readiness for Hospital Discharge Scale-Parent Form (RHDS-FM) and Parents’ Perception of Uncertainty Scale-Family Member(PPUS-FM). …”
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Impact of Nutritional Support for Tuberculosis on Intermediate and Terminal Undernutrition and Treatment Outcomes (INSTITUT) study: a protocol for a quasi-experimental study to ass... by Dissou Affolabi, Chelsie Cintron, Madolyn Dauphinais, Attannon Arnauld Fiogbe, Mohammed Fall Dogo, Safiou Ate, Christine Adjonou, Kokou Agossou, Susie Jiaxing Pan, Marius Esse, Benjamin Ade, Komi Séraphin Adjoh, Pranay Sinha, Kobto G Koura

“…Comparing treatment outcomes of PWTB treated in Benin and Togo can help us understand the impact of nutritional support for PWTB.Methods and analysis We designed a programmatic, prospective cohort study to assess the treatment outcomes among persons with pulmonary tuberculosis under programmatic conditions. …”
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CBCT Analysis of Mandibular Ramus as a Donor Site for Cortical Bone Graft: A Retrospective Analytical Study by Pallabi Das, Samiran Ghosh, Kaushik Dutta, Richi Burman, Amit Ray, Debolina Pramanick, Siddhartha Chatterjee, Somak Saha

“…Aim: To evaluate the maximum extent and different dimensions of cortical bone graft that can be harvested from the ascending ramus of the mandible while maintaining a safe zone from anatomical vital structures by using Cone Beam Computed Tomography (CBCT). Materials and Methods: A retrospective analytical study was carried out in the Department of Oral and Maxillofacial Surgery, Guru Nanak Institute of Dental Sciences and Research, Kolkata, West Bengal, India from February 2021 to September 2022. …”
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Effect of Physical Activity on Physical and Mental Health in Young Cancer Patients and Survivors: A Systematic Review of RCTs and CCTs by Ann Christin Schneider, Sofia Anzeneder, Lars Rehbein, Eva Katharina Brack, Mirko Schmidt, Valentin Benzing

“…This systematic review aimed to summarize findings from randomized controlled trials (RCTs) and clinical control trials (CCTs) evaluating the impact of PA interventions on physical and mental health outcomes in YCP and survivors. Methods A systematic search was conducted in APA PsycINFO, PubMed, SPORTDiscus, Web of Science, Embase, and Scopus. …”
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Effect of narrative nursing combined with Traditional Chinese Medicine foot soaking and auricular acupoint pressing in the treatment of post-stroke sleep disorder (叙事护理联合中药泡足和耳穴贴压治... by CHAI Jingjing (柴晶晶), MENG Xiangnan (孟祥楠)

“…Objective To investigate the effect of narrative nursing combined with Traditional Chinese Medicine foot soaking and auricular acupoint pressing in the treatment of post-stroke sleep disorder. Methods From June 2022 to December 2022, 80 patients with sleep disorder after stroke admitted to the Rehabilitation Department of Beijing Longfu Hospital were selected and randomly divided into a control group and a study group, with 40 patients in each group. …”
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Identification of Three Significant Genes Associated with Immune Cells Infiltration in Dysfunctional Adipose Tissue-Induced Insulin-Resistance of Obese Patients via Comprehensive B... by Ming Zhai, Peipei Luan, Yefei Shi, Bo Li, Jianhua Kang, Fan Hu, Mingjie Li, Lei Du, Donglei Zhou, Weixia Jian, Wenhui Peng

“…In this study, we would like to explore the correlation of genes and immune cells infiltration in adipose tissue via comprehensive bioinformatics analyses and experimental validation in mice and human adipose tissue. Methods. Gene Expression Omnibus (GEO) datasets (GSE27951, GSE55200, and GSE26637) of insulin-resistant individuals or type 2 diabetes patients and normal controls were downloaded to get differently expressed genes (DEGs), and GO and KEGG pathway analyses were performed. …”
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Cognitive function differs across healthy lifestyle behavior profiles: a 10-year population-based prospective cohort study by Huixiu Hu, Yajie Zhao, Di Guo, Ying Deng, Huanhuan Luo, Yuqing Hao, Chao Sun, Kang Yu

“…This study aimed to identify distinct profiles of individuals based on healthy lifestyle behaviors and to examine associations between these profiles and cognitive function in older Chinese adults. Methods: We used a prospective cohort, including 5381 participants of the Chinese Longitudinal Healthy Longevity Survey (CLHLS) between 2008 and 2018, aged 65 years and older with normal cognition at baseline. …”
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Therapeutic Potential of <i>Cajanus cajan</i> (L.) <i>Millsp</i>. Leaf Extract in Modulating Gut Microbiota and Immune Response for the Treatment of Inflammatory Bowel Disease by Mingzhang Lin, Linghua Piao, Zhendong Zhao, Li Liao, Dayong Wang, Haiwen Zhang, Xiande Liu

“…However, its effects on IBD remain largely unexplored. <b>Methods:</b> In this study, the major compounds from <i>Cajanus cajan</i> leaf extract (CCLE) were initially characterized by LCMS-IT-TOF. …”
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Platelet-rich plasma combined with gypenosides for the treatment of psoriasis-like inflammation in mice by LI Dandan, WANG Bing, GE Yu, CHENG Hong, LI Mengxue, WANG Zhicheng, XIA Rong

“…[Objective] To investigate the therapeutic effect of platelet-rich plasma (PRP) subcutaneous injection combined with gypenosides (GPs) oral administration on BALB/c mouse psoriatic inflammation and explore its mechanism of action. [Methods] The 6-8 week-old female SPF BALB/c mice were randomly divided into five groups: control, model, PRP, GPs and PRP+GPs group, with 5 mice in each group. …”
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Peripheral endothelial dysfunction in myalgic encephalomyelitis/chronic fatigue syndrome by Nadja Scherbakov, Marvin Szklarski, Jelka Hartwig, Franziska Sotzny, Sebastian Lorenz, Antje Meyer, Patricia Grabowski, Wolfram Doehner, Carmen Scheibenbogen

“…The aim of the present study was to examine peripheral endothelial function in patients with ME/CFS. Methods and results Thirty‐five patients [median age 40 (range 18–70) years, mean body mass index 23.8 ± 4.2 kg/m2, 31% male] with ME/CFS were studied for peripheral endothelial function assessed by peripheral arterial tonometry (EndoPAT2000). …”
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